Alogliptin and Pioglitazone is known under the brand name Oseni in the US and comes in oral tablet form. This medication is only available on prescription from your doctor or other health professional.
This medication is designed to be used in conjunction with a healthy diet and regular exercise in order to treat the high blood sugar levels that are caused by type 2 diabetes. Diet and exercise are crucial elements in a lifestyle program that is designed to control and manage this health condition.
The Alogliptin component of the medication controls the blood sugar levels by stimulating the pancreas to produce more insulin. In addition, it causes the liver to stop producing glucose (sugar) when there is already an excess of sugar in the patient's blood. Pioglitazone works by improving the body's ability to synthesize insulin.
Alogliptin and Pioglitazone is not effective in patients who have type 1 or insulin-dependent diabetes.
Alogliptin and Pioglitazone is formulated to control and manage the symptoms of your condition. However, you may experience some unwanted side-effects while you are taking it. Before you commence your course of Alogliptin and Pioglitazone, be sure to tell your doctor if you have ever experienced any side-effects or allergic reactions to any other medication. This includes over-the-counter products, vitamin supplements or herbal remedies. You must also tell your doctor if you are allergic to any foods, preservatives, dyes or animal derivatives.
The side-effects mentioned below are sometimes experienced by patients taking Alogliptin and Pioglitazone. However, you should be aware that this list is not all-inclusive, and if you do notice anything unusual about your behavior or if you begin to feel ill after you start taking this medicine, you should contact your doctor as soon as possible.
Side-effects that are commonly experienced by some patients taking Alogliptin and Pioglitazone include feelings of depression, confusion, and anxiety. You may also find that your sleep patterns are disrupted or you begin to have nightmares. Some patients report feelings of extreme fatigue, tiredness or weakness. On a physical level, you might find that you have blurred vision, headaches, dizziness, and nausea. The medication can also cause flu-like symptoms, including chills, cold sweats, chest pain or tightness in the chest. You may notice that you have a decreased urine output. Alogliptin and Pioglitazone can also cause increased hunger and consequent weight gain.
Other common side-effects that you might experience include a fast or irregular heartbeat, irregular breathing or problems breathing. Some people notice that the veins in their neck appear dilated and they have swelling to their fingers, lower legs, feet, or face. You might also feel that your speech is slurred and you feel shaky.
If you experience any of these side-effects, you should seek medical attention immediately.
Some of the side-effects that patients experience while taking Alogliptin and Pioglitazone do not usually require medical attention. The following side-effects often resolve themselves as the body adjusts to the medication. There may also be ways to reduce or eliminate some of these side-effects, and your doctor will discuss this with you. If any of these side-effects become particularly bothersome or fail to resolve within a few weeks, ask your doctor for advice.
If you notice any other side-effects that are not mentioned above, check with your doctor.
There is no evidence to suggest that taking Alogliptin and Pioglitazone can have an adverse effect on children or on the elderly.
Your doctor will give you a special meal plan to follow while you are taking Alogliptin and Pioglitazone. In order for this medication to work properly, it is essential that you stick to the meal plan. This is the most important aspect of controlling your type 2 diabetes. You must also take regular exercise and test the sugar levels in your blood or urine as directed by your health professional. The medication will come with a Medication Guide, which you should read carefully and be sure to follow the instructions it contains. If you have any questions, ask your doctor for clarification.
Alogliptin and Pioglitazone may be taken with or without food. Swallow each tablet whole. You must not crush, break, split or chew the tablets.
The dose of this medication will vary between patients. You should take the medicine as instructed by your doctor or the directions on the product packaging. The dosage information that follows is the average recommended for this medication. If the dose that you are prescribed is different, do not alter it unless you are instructed to do so by your treating physician.
The dose that you are prescribed will depend on the strength of the preparation. In addition, the number of doses that you are required to take each day and their frequency will depend on the condition for which you are being treated.
Adults: one tablet per day. This tablet may be formulated with 25 mg Alogliptin plus 15 mg Pioglitazone or 25 mg Alogliptin plus 30 mg Pioglitazone. Your doctor may decide to adjust the dose as required. However, the dose does not normally exceed 25 mg Alogliptin plus 45 mg Pioglitazone per day.
It is not recommended to use this medication for children.
In the event that you miss your prescribed dose of this medication, you should try to take it as soon as possible. However, if it is almost time for your next scheduled dose, do not double-dose. Instead, you should revert to your usual dosing schedule.
In the case of accidental overdose, where serious side-effects present themselves, such as losing consciousness or severe breathing difficulties occur, you should call 911 immediately. If an overdose occurs but no immediate side-effects are apparent, contact your doctor or your local poisons advice centre for advice without delay.
There are some forms of medication that should never be used together. However, in other cases it may be safe and suitable to use two or more different medicines in conjunction with each other, even though an interaction may take place. Under such circumstances, your doctor may decide to change the dose of one or more of your medications or he may suggest that you take other precautions to reduce or negate the effect of any interactions that might occur.
You should always tell your doctor straight away if you are already taking any other form of medication. This should include herbal remedies, vitamin supplements or non-prescription medicines. Some medicines should not be taken with eating certain types of foods, tobacco or alcohol, as this may cause interactions to occur. Be sure to discuss the use of this medication with your doctor before you begin taking it if you smoke or use alcohol, or regularly eat certain foodstuffs.
The following medications have been shown to have an interaction with Alogliptin and Pioglitazone and should not be taken together with this drug:
In addition to discussing with your doctor any allergies that you suffer from and mentioning any other drugs or vitamin supplements that you are taking, it is also very important that you also mention any existing health conditions that you have, before you start taking Alogliptin and Pioglitazone.
While you are taking Alogliptin and Pioglitazone, it is very important that you attend your doctor for regular check-ups. These meetings allow your doctor to check that your medication is working properly and to decide whether you should continue with it or if an alternative might suit you better. You will also have the opportunity to discuss any bothersome side-effects that you have noted since starting your course of Alogliptin and Pioglitazone. Your doctor may also take blood and urine tests to check for any unwanted effects that may be caused by the medication.
Women who are of childbearing age should be aware that they are at risk of becoming pregnant while taking this medication. If you fall into this group and you have experienced ovulating in the past or have had irregular periods, you should note that Alogliptin and Pioglitazone may cause you to ovulate, which could increase your chances of becoming pregnant. If you are concerned about unwanted pregnancy, discuss birth control options with your doctor or pharmacist.
Alogliptin and Pioglitazone can cause fluid retention (too much water in the body). This can cause rapid weight gain, shortness of breath, chest pain or discomfort, and feeling excessively tired or weak. You may also notice an irregular heartbeat or irregular breathing, swelling of your hands, ankles, feet, or wrists. All these can be symptomatic of heart problems or fluid retention and you should consult your doctor immediately if you begin to experience any of these side-effects.
The use of Alogliptin and Pioglitazone can cause pancreatitis (inflammation and swelling of the pancreas). If you have sudden severe stomach pains, constipation, chills, nausea, loss of appetite or vomiting, lightheadedness or fever, you should contact your treating physician straight away.
In some people, this medication can cause serious allergic reactions, including anaphylaxis, Stevens-Johnson syndrome, and angioedema. All these conditions can be fatal if not treated promptly. If you experience any of the following symptoms while you are taking Alogliptin and Pioglitazone, contact your doctor immediately or call 911 if your doctor's surgery is closed:
Alogliptin and Pioglitazone can cause serious liver problems in some patients. Signs of liver problems include pale stools, dark urine, pain or tenderness in the upper part of your stomach, nausea and vomiting, yellowing of the eyes or skin (jaundice). Any of these signs should be reported to your doctor without delay.
The prolonged use of Alogliptin and Pioglitazone can cause osteoporosis (weakened bones) in women. Ask your doctor's advice on how to prevent fractures and keep your bones strong.
Using Alogliptin and Pioglitazone for a long period of time can increase the risk of bladder cancer. If you notice blood in your urine, a frequent or dramatically increased feeling that you need to urinate, discomfort when urinating, or pains in your stomach, back, or lower abdomen, tell your doctor right away.
Alogliptin and Pioglitazone can cause problems with vision. If you notice any deterioration in your eyesight while taking this medication, check with your doctor. Your doctor may suggest that you have your eyes tested regularly by an ophthalmologist while you are taking this medication.
This medication can cause low blood sugar (hypoglycemia). This condition can also occur if you miss or delay a meal, drink alcohol, exercise more than usual, cannot eat as usual because of nausea or vomiting, take certain other medicines, or take another form of diabetes medicine (insulin, glipizide, glimepiride, glyburide, or metformin). You must address low blood sugar before it causes unconsciousness. For more advice on how to deal with and prevent low blood sugar, have a chat with your doctor.
Alogliptin and Pioglitazone can also cause hyperglycemia (high blood sugar). This can happen if you do not take the correct dose of your medicine or if you miss a dose. High blood sugar can also happen if you do not follow your prescribed diet plan or overeat. Infection or fever can also cause your blood sugar levels to become too high, as can a lack of exercise. Hyperglycemia is a very serious condition that must receive immediate appropriate medical treatment. For more advice on how to deal with and prevent your blood sugar levels from becoming too high, have a chat with your doctor.
It is recommended that you wear a medical identification alert (ID) bracelet or neck chain in case you require emergency attention for a problem that occurs as a result of your diabetes. In addition, it is a good idea to carry an ID card in your purse or wallet, giving details of your diabetes and listing any medication that you are taking.
Alogliptin and Pioglitazone can sometimes cause debilitating and severe joint pain in some patients. If you experience this problem while using this medication, you should consult your doctor immediately.
Always keep Alogliptin and Pioglitazone in an airtight container and at room temperature.
Do not freeze this medication.
Do not place Alogliptin and Pioglitazone where it could be exposed to direct sunlight. Keep your medication away from heat sources and moisture.
Keep the medication out of reach of children and pets. In the event that a pet consumes Alogliptin and Pioglitazone, you should seek veterinary advice immediately.
Never use medication that has become out-of-date. Discard any medication that has damaged packaging or appears to have been opened.
Ask your doctor or pharmacist for advice on the best way to dispose of any unwanted or out-of-date medication. Do not flush the Alogliptin and Pioglitazone tablets down the toilet or drain. Never discard unwanted medicine with your trash; they could be found and consumed by children or animals.
Alogliptin and Pioglitazone in combination is a medication that is used to treat the high blood sugar levels that are caused by type 2 diabetes.
The medication can cause a variety of side-effects and may also increase the risk of other health problems such as liver problems, pancreatitis, unwanted pregnancy, visual disturbances, bladder cancer, low blood sugar, fluid retention, and severe allergic reactions.
Common side-effects include irregular breathing or problems breathing, and a fast or irregular heartbeat. Some people experience swelling in the lower legs, feet, fingers, or face. Others report that their neck veins appear dilated. You might also find that your speech becomes slurred and that you feel shaky. Most of these minor side-effects resolve themselves within a couple of weeks of starting your first course of this medicine.
This medication cannot cure type 2 diabetes. However, Alogliptin and Pioglitazone is highly effective and beneficial to people with type 2 diabetes, when taken correctly as prescribed by a doctor. To get the best results from this medication, you should work closely with your doctor to establish the correct dose and frequency of use. This means that you must attend for regular check-ups, blood and urine tests. You must also test your blood sugar levels as directed by your doctor.