Aminocaproic Acid

Aminocaproic acid intravenous is only available with a doctor’s prescription and comes under the common brand name Amicar.

Overview:

Amicar helps to control bleeding caused by a condition where blood doesn’t clot properly (fibrinolysis). This can cause severe bleeding after some surgeries or in some conditions, including bleeding disorders, cancer, and liver disease. Aminocaproic acid works to help blood clot the way it should. Aminocaproic is in a drug class known as antifibrinolytics.

Aminocaproic acid is available as a liquid (solution) that is injected through an IV by a doctor in a clinic or hospital setting or by a patient at their home. It’s normally injected over a period of around eight hours to control bleeding. Patients injecting the medication at home should take it exactly as instructed. Don’t take less or more of Aminocaproic acid injection or take it more times than ordered by your doctor.

In some cases, Aminocaproic acid intravenous is also used to treat eye bleeding due to an injury. Discuss the risks of taking Aminocaproic acid for your condition with your doctor.

Amicar can serve other purposes as well; get more information from your pharmacist or physician.

Conditions treated:

  • Bleeding after operation
  • Bleeding in hemophilia
  • Bleeding due to Fibrin breakdown
  • Prevent peri-operative bleeding

Type of medicine:

  • Hemostatic

Side effects:

Along with its beneficial effects, Amicar can cause some negative side effects. While not all of these side effects may happen, they may require treatment if they do happen.

Contact your doctor as soon as possible if you go through any of these Aminocaproic acid injection side effects while using the medication.

Frequency unknown:

  • Dark-colored urine
  • Bleeding gums
  • Blurred vision
  • Anxiety
  • Black, tarry feces
  • Chest pain/discomfort
  • Inability to see some colors, especially yellow or blue
  • Chills
  • Cough or hoarseness
  • Confusion
  • Reduced amount or frequency of urination
  • Difficulty with moving
  • Labored/difficult breathing
  • Difficulty with speaking
  • Lightheadedness or dizziness
  • Difficulty with swallowing
  • Lightheadedness, faintness, or dizziness when suddenly rising from a sitting or lying position
  • Headache
  • Double vision
  • Fast heartbeat
  • Fainting
  • Fever with/without chills
  • Hives
  • General feeling of weakness or tiredness
  • General feeling of illness or discomfort
  • Inability to move legs, arms, or facial muscles
  • Increased thirst
  • Joint pain
  • Inability to speak
  • Loss of appetite
  • Itching of skin
  • Side or lower back pain
  • Muscle cramping or aching
  • Muscle spasm or cramps
  • Muscle stiffness or pain
  • Muscular pain, weakness, tenderness, or wasting
  • Nausea and vomiting
  • Skin rash
  • Numbness and tingling sensation on the fingers, toes, or face
  • Pain in the legs, arms, lower back, particularly pain in the heels or calves on exertion
  • Difficult/painful urination
  • Pale, bluish, or cold feet or hands
  • Red spots on skin
  • Problems with clotting or bleeding
  • Swelling or puffiness of eyelids or near the eyes, lips, face, or tongue
  • Shortness of breath
  • Slow speech
  • Irregular or slow heartbeat
  • Sore throat
  • Ulcers, white spots, or sores in the mouth or on the lips
  • Swelling
  • Troubled breathing with sweating
  • Swelling of the lower legs, fingers, or face
  • Swollen joints
  • Swollen glands
  • Tenderness, swelling, pain, skin discoloration, warmth, and noticeable superficial veins on the affected area
  • Tightness in chest
  • Unusual bruising or bleeding
  • Absent or weak pulses in legs
  • Wheezing
  • Weight gain

Some Amicar side effects can occur that normally don’t require treatment. Such side effects may cease during treatment while your body becomes accustomed to the medication. Additionally, your healthcare giver can give you directions on how to prevent or minimize some of the side effects. If any of these side effects persist, bother you or you have questions about them, consult your doctor.

Frequency unknown:

  • Stomach or abdominal pain
  • Confusion as regards people, time, or place
  • Continuing buzzing/ringing or other unusual noise in ears
  • Diarrhea
  • Decreased vision
  • Ejaculation without semen
  • Hearing loss
  • Mood or mental changes
  • Having false beliefs that can’t be challenged by fact
  • Stuffy nose
  • Watery eyes
  • Unusual restlessness, nervousness, or excitement
  • Feeling, hearing, or seeing things that aren’t there

Dosage:

Your doctor will carry out blood tests to ensure you don’t have problems that would prevent safe use of Aminocaproic acid intravenous.

Follow all the instructions on the pack. Don’t take larger or smaller Aminocaproic acid doses or for longer than is recommended.

Your healthcare giver will prescribe the right treatment for you. Don’t alter your treatment without consulting your healthcare giver.

Aminocaproic acid solution is injected through an IV or straight into a vein.

You may be taught how to inject yourself through an IV. Don’t administer this medication to yourself if you don’t know how to inject yourself and dispose of needles properly, IV tubing, as well as other equipment used.

You should begin taking Aminocaproic acid solution as soon as you start bleeding. Your first dose could be much larger than those you take later on. Carefully follow your doctor’s instructions on dosing.

Treatment with this medication is normally continued until the bleeding stops or on an hourly basis for eight hours.

Measure the liquid medication with the provided syringe, or with a medicine cup or measuring spoon. If you don’t have a device for measuring doses, get one from your pharmacist.

Mix injectable Aminocaproic acid with a liquid before use. If you’re giving the injections yourself, make sure you know how to mix and store the medication properly.

Don’t take the injectable medication if it’s got particles or its colors have changed. Get new medication from your pharmacist.

Use a disposable syringe and needle only once.

Call your doctor immediately if your symptoms persist after taking Amicar.

While using this medication, you may need regular blood tests. Your kidney may also be tested. Aminocaproic acid may cause long-term effects in your body. After you discontinue this medication, you may need regular medical exams for some time.

Amicar overdose symptoms can include fainting, feeling lightheaded, or urinating less than normal.

Children need adult assistance in applying this medication.

As Aminocaproic acid is taken when needed, you might not need a dosing schedule. Take any doses you miss immediately once you remember. If your next scheduled dose is approaching, forgo the missed dose. Don’t take additional medication to even out the missed dose. If you miss a dose, you can also call your doctor for directions on what to do.

Interactions:

Drug interactions can alter how your medicines work or up your chances of serious side effects.

Your pharmacist/doctor probably knows any potential medication interactions and can be checking them on your behalf.

Don’t start, discontinue, or alter the dose of any drug before consulting your pharmacist/doctor first.

Some of the products that can interact with Amicar include tretinoin and blood clotting factors (including anti-inhibitor coagulant complex, Factor IX complex).

This medicine may affect some lab tests, potentially resulting in false test results. Be sure to tell your doctor and lab staff that you’re using this medication.

This list isn’t complete and other drugs can interact with Amicar. Tell your healthcare giver about all drugs you use, including herbal products, vitamins, over-the-counter, and prescription drugs. Don’t start using a new drug without your doctor’s knowledge.

Warnings:

Tell all your healthcare professionals if you have allergies to Amicar or any other drugs.

Tell all your healthcare providers what prescription and over-the-counter medicines, herbal products, and dietary supplements you’re using or plan to use. Make sure to cite any of these drugs: factor IX (Mononine, AlphaNine SD); factor IX complex (Proplex T, Profilnine SD, Bebulin VH); as well as anti-inhibitor complex. Your physician may need to adjust the dosage of your drugs or carefully monitor you for side effects.

Tell your physician if you’ve ever had or have blood clots or liver, kidney, or heart disease.

Tell your physician if you intend to get pregnant, are pregnant, or are nursing a child. If you conceive while using Amicar, call your doctor.

If you’re having an operation, e.g. dental surgery, notify your dentist or doctor if you’re using Amicar.

Aminocaproic acid injection isn’t suitable for persons younger than 18.

It’s unclear where Amicar is released into human milk or if it may affect a breastfeeding infant. Tell your primary healthcare giver if you’re breastfeeding.

Follow your physician’s directions on any restrictions on activity, food, or drinks.

Storage:

Keep Aminocaproic acid injection at room temperature in a tightly sealed container.

Keep the medicine away from moisture and light.

Don’t freeze Aminocaproic acid injection.

Don’t keep the medication in the bathroom.

Keep all drugs away from kids and pets.

Don’t pour drugs down the drain or flush them down the toilet unless directed to do so.

Properly discard Aminocaproic acid solution when you no longer need it or it’s expired.

Call your local garbage disposal firm or pharmacist for ways on how to safely dispose of this medication.

Summary:

Honor all of your lab and doctor visits. Your doctor will arrange some lab test to assess your response to Amicar.

It’s vital to have a list of all drugs you’re taking (prescription and nonprescription), and any products like minerals, vitamins, or other nutritional supplements. Be sure to give your doctor or other healthcare professional this list each time you visit them. It’s also vital information to have on hand whenever there’s an emergency.

A trained healthcare provider will give you Amicar in a clinic or hospital setting. Amicar is given via a needle positioned in a vein. The medication must be given slowly, so the IV tube must remain in place for around 30-60 minutes.

The existence of some medical conditions can affect Amicar use. Be sure to report to your physician if you suffer from any other medical conditions, especially:

  • Active blood clots
  • History of blood clots
  • Blood in urine (hematuria)—make sure to use Amicar carefully. It may make this condition worse.
  • Kidney disease—Aminocaproic acid injection side effects can be increased due to slow elimination of the drug from the body.
  • Disseminated intravascular coagulation (DIC)—people who have this blood clotting problem should not use Aminocaproic acid injection.
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Last Reviewed:
December 10, 2017
Last Updated:
December 22, 2017
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