Ammonium Molybdate (Injection, Intravenous)

While most people get sufficient nutrients from their diet, some individuals have trouble retaining or absorbing certain nutrients, and require medically-provided supplements. Molybdenum is one such nutrient, and Ammonium Molybdate in an injectable form is given to people who suffer severe molybdenum deficiencies.

Overview

Ammonium Molybdate is an injectable form of the mineral molybdenum. Molybdenum is a necessary mineral for human health and is usually provided to most people by eating a normal, healthy diet. It forms part of enzymes in the human body that are needed for healthy functioning. For most individuals, there is no need to take a supplement because they already get enough molybdenum every day. Some people may also be getting additional molybdenum by taking one of the many vitamin and mineral supplement pills that are available generally as an over-the-counter supplement.

For others, however, getting enough molybdenum in their diet is not possible, and it becomes necessary to treat their deficiency. Without the proper functioning of the enzymes, there can be a buildup of certain substances in the body. It is rare to have a molybdenum deficiency, however those individuals who do suffer from molybdenum deficiency can experience a variety of symptoms. Some of these symptoms include a rapid heartbeat, headaches, night blindness, nausea, and vomiting. Other symptoms can be swelling in various parts of the body, a feeling of being tired or disoriented, and possibly even a coma. In this case, a more intensive therapy may be required than simply taking an over-the-counter supplement.

Using Ammonium Molybdate Injectable is a way for individuals to get this intensive therapy and remedy their deficiency. Patients with severe deficiencies who are given the injectable Ammonium Molybdate solution find that the deficiency can be remedied over the course of approximately 21 days of treatment.

How much the average person needs of molybdenum in their diet is not known to a precise degree. Molybdenum is ingested as part of a healthy diet, which includes fruits and vegetables. How much molybdenum is in food is the result of the type of soil where the food is grown. Certain vegetables, grains and low-fat milk are sources of molybdenum, as well as peas, beans, some cereals and leafy greens. The amount of molybdenum can be higher or lower depending on the soil in which the vegetable and grains are grown.

This mineral supplement can safely be given to adults as well as children if the recommended daily dose is followed. Since having low molybdenum levels is rare, there is no specific, established daily guideline for a specific intake requirement, but rather just recommended amounts. Below are amounts that are considered adequate for most people:

  • Adults and adolescents: 75 to 250 mcg.
  • Infants and children:
    • Birth to 3 years of age: 15 to 50 micrograms (mcg).
    • 4 to 6 years of age: 30 to 75 mcg.
    • 7 to 10 years of age: 50 to 150 mcg.

This supplement is administered by a doctor, or under the supervision of a doctor. The correct dosage of the Ammonium Molybdate intravenous injection will be determined by the physician, who will check the patient's metabolic levels and other medical history, and base their decision on the severity of the individual patient.

Conditions Treated

  • Molybdenum deficiency

Type of Medicine

  • Mineral supplement

Side Effects

For patients taking Ammonium Molybdate Injectable, for both adults and children, there are no reported side effects for dosages within the normal levels of molybdenum.

For patients taking high dosages of molybdenum, there may be problems for patients suffering from a copper deficiency. Molybdenum can make a copper deficiency worse, as it causes the body to excrete copper in the urine. By providing a complete medical history to the treating doctor, patients can help the doctor determine whether a copper supplement is advisable while taking this treatment.

For young children taking the Ammonium Molybdate Injection, dosage level will be crucial, as taking too much molybdenum can result in kidney damage, damage to the central nervous system, or bone damage.

Generally, however, the amount of molybdenum that is contained in the Ammonium Molybdate Injectable is a very small amount. It is very unlikely that at this dosage level, there will be any adverse reaction that results from having this injection.

While few side effects have been reported, there may still be some unwanted effects in some individuals. Although these side effects are rare and may not occur, if they do appear while in treatment, it's important to seek medical attention.

Patients should check with their doctor if any of these side effects occur. Most of these are associated with potential overdose and elevated levels of molybdenum:

  • Joint pain
  • Pain in the side, lower back, or stomach
  • Swelling of lower legs or feet

There are other side effects which are not included here, but may occur in some patients. For patients that notice any other unwanted or unexpected effects, they should talk to their healthcare professional. Patients can also contact the FDA to report side effects by calling 1-800-FDA-1088.

Dosage

How much the doctor prescribes will depend on the severity of the condition being treated, and therefore will be different for different patients. The Ammonium Molybdate Injectable will be administered by a doctor, or should be administered only under the supervision or direction of a doctor.

Ammonium Molybdate Injectable comes in a vial form, with 25 micrograms (mcg) of molybdenum per milliliter. The recommended dosages are as follows:

  • Adults who have a stable metabolism: suggested dose is 20 to 120 mcg of molybdenum per day.
  • Adults who have metabolic problems: to be determined by a physician.
  • Children: dosages are determined by the physician based upon age, weight and physical condition.

For adults who are being treated for a severe molybdenum deficiency, it has been reported that taking Ammonium Molybdate Injectable at a level of 163 mcg per day for 21 days can reverse the deficiency symptoms. At these levels, there are no reported serious side effects.

Major Drug Interactions

For Ammonium Molybdate Injectable, there are no reported drug interactions for patients taking normal amounts of molybdenum.

Warnings

If the patient has other medical problems, it is possible that the dosage level of molybdenum could make these problems worse. As with all medications or supplements, patients should always provide a full medical history to the treating physician.

Conditions which may be affected by taking Ammonium Molybdate Injectable are:

  • Copper deficiency - Molybdenum can make a copper deficiency worse.
  • Kidney disease or liver disease can lead to higher levels of molybdenum in the blood, which can cause additional, unwanted side effects.

For patients with a copper deficiency, the treating physician may order frequent tests to check the patient's metabolism and levels of copper.

In the injectable form, this product contains aluminum, which for some patients may be toxic. Particularly where this supplement is administered to children, the amount of aluminum may cause kidney problems. Problems that can result in certain young children, particularly premature babies, include liver damage, damage to the nervous system and bone issues. Children should only be given this supplement with the supervision of a doctor.

Storage

This supplement is sold in vials, and administered in a doctor's office. Usually, home storage will not be an issue, unless a parent is administering to a child. Follow all instructions of the treating physician as well as packaging information.

Ammonium Molybdate Injectable should be kept at room temperature (20-25 degrees Celsius/68-77 degrees Fahrenheit). Do not freeze.

This supplement should be kept out of the reach of children. As with all medications, do not keep outdated drugs or any medications that are no longer needed. Any medication that is no longer in use should be disposed of properly. For proper disposal of this and other medications no longer in use or past their expiration date, check with a health or law enforcement professional.

Summary

For most people, getting enough molybdenum in their diet is not a problem: it's contained in a variety of vegetables, grains and in milk. For adults and children with a molybdenum deficiency, an over-the-counter supplement will help.

However, certain patients have a severe molybdenum deficiency, which is where the Ammonium Molybdate Injectable can help. A doctor can prescribe injections of molybdenum at levels which will be enough to cure the deficiency. These injections should be administered by a doctor or under the supervision of a doctor.

Ammonium Molybdate Injectable can be given to both adults and children. There are virtually no side effects or toxicity reported with taking molybdenum at normal levels.

It's important to note however that certain adults with liver or kidney disease, or who have copper deficiencies, may have additional instructions as taking high levels of molybdenum may worsen their condition. For young children, high doses of Ammonium Molybdate Injectable can also cause severe problems such as kidney damage, damage to the central nervous system, or bone problems. Ammonium Molybdate Injectable as provided also includes aluminum, which may be a concern for some patients. A doctor can determine proper levels depending on the patient's individual medical history and needs.

If taken correctly, there are no reported toxic side effects or other problems with taking Ammonium Molybdate Injectable solution.

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Last Reviewed:
December 10, 2017
Last Updated:
April 04, 2018
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