Cefditoren Pivoxil (Oral)

Cefditoren pivoxil helps treat some lung and throat infections like bronchitis and tonsillitis, as well as some skin infections.


Cefditoren pivoxil helps with treating diseases caused by bacteria by killing or preventing the growth of bacteria.

It's used to treat certain throat and lung diseases such as tonsillitis and bronchitis, and some skin diseases.

Cefditoren pivoxil comes in the form of a tablet that's taken by mouth and is only available with a physician's prescription.

Before you decide to take a medicine, you must weigh its possible risks against the benefits it's likely to bring. This is one decision you'll make with your doctor. Before you use Spectracef, consider these factors.

Allergies - have you ever experienced any allergic or odd reaction to Spectracef or any other drug? If so, tell your physician. Also tell him or her if you have any other sorts of allergies, like to animals, foods, preservatives, or dyes. Before taking non-prescription products, be sure to carefully read the ingredients on the package or label.

Pediatric - studies on Cefditoren pivoxil have only been conducted in adults, and there's no specific data comparing Cefditoren use in kids younger than 12 with use in all other age groups.

Geriatric - Cefditoren pivoxil has been examined and hasn't been found to cause different problems or side effects in older adults.

Pregnancy - animal studies haven't revealed any evidence of risk to the unborn child. However, talk to your doctor before using this medicine if you are pregnant or want to become pregnant.

Breastfeeding - studies in women reveal that Cefditoren pivoxil poses negligible risk to the baby when taken during breastfeeding. However, consult your doctor before breastfeeding while using this medication.

Conditions treated

  • Tonsillitis and strep throat
  • Chronic bronchitis
  • Skin infection
  • Pneumonia

Type of medicine

  • Antibiotic

Side effects

Diarrhea, vomiting, nausea, or a headache can occur when using Spectracef. If any of these side effects get worse or last, inform your pharmacist or doctor at once.

Bear in mind that your physician has prescribed Cefditoren pivoxil because he/she has judged that it'll be more beneficial to you than risky. Many people taking Cefditoren pivoxil don't suffer serious side effects.

Tell your doctor promptly if you experience any serious effects, including:

  • Easy bleeding/bruising
  • Unusual tiredness
  • Mental/mood changes (e.g. confusion)
  • Seizures
  • Signs of liver disease (e.g. chronic nausea/vomiting, loss of appetite, dark urine, yellowing skin/eyes, stomach/abdominal pain)
  • Signs of kidney disease (e.g. change in urine amount)
  • New signs of illness (e.g. unending sore throat, chills, fever)
  • Sudden baffling weight gain
  • Swelling of ankles/feet
  • Increased urination/thirst
  • Muscle weakness

Signs of reduced blood sugar (e.g. sudden sweating, fast heartbeat, shaking, hunger, dizziness, blurred vision, tingling hands/feet)

Cefditoren pivoxil may rarely cause Clostridium difficile-related diarrhea (a very serious intestinal condition) due to a strain of resistant bacteria. The diarrhea may occur weeks to months after the end of treatment or during treatment. Tell your physician promptly if you develop unending diarrhea, abdominal/stomach pain or cramping, and mucus or blood in your stool.

Don't use narcotic pain medications or anti-diarrhea products if you develop any of the above symptoms as such products can make them worse.

Using Cefditoren pivoxil repeatedly or for a long time may cause a new candidiasis yeast infection or oral thrush. Call your physician if you notice a change in your vaginal discharge, white areas in your mouth, or other symptoms.

Cefditoren pivoxil rarely causes a severe allergic reaction. However, seek medical attention at once if you notice these symptoms of a severe allergic reaction:

  • Severe dizziness
  • Rash
  • Itching/swelling (particularly of the throat/tongue/face)
  • Difficult breathing
  • This isn't a full list of potential Spectracef side effects. If you have other effects not mentioned above, see your doctor as well as your pharmacist.


To help get rid of your infection completely, continue taking Cefditoren pivoxil for the entire duration of treatment, no matter if your symptoms start to improve shortly. Also, if you cease taking Cefditoren too early, your symptoms may recur.

This medication works best when you have a consistent amount of it in your urine or blood. To maintain a consistent amount, make sure to take all doses. In addition, it's best to take your doses at even intervals, whether day or night. If you take 4 doses daily, for example, you should space the doses around 6 hours apart. Check with your physician if this gets in the way of your daily activities or sleep, or if you need assistance in planning the right times to take Cefditoren pivoxil.

Take Spectracef exactly as your doctor prescribed. Don't take it in smaller or larger amounts, or for longer than prescribed. Follow the instructions found on the label.

Take Cefditoren pivoxil with one glass of water.

Cefditoren pivoxil is best absorbed if you eat food with it.

Take Cefditoren pivoxil for the whole duration prescribed by your physician. Your symptoms may improve before the infection completely clears up. Cefditoren pivoxil won't treat viral infections like flu or the common cold.

This medicine can make you have wrong results with some medical tests, for example, urine sugar (glucose) tests. Be sure to inform your doctor that you're taking Cefditoren pivoxil.

If you have missed a dose, take it immediately you remember. If it's about time for another dose, take the medication at the next scheduled time and skip the dose you missed. Don't take extra medication to compensate for missed doses.

Seek emergency medical help if you think you've taken too much of Cefditoren. Overdose symptoms can include nausea, vomiting, stomach pain, diarrhea, and seizure (convulsions).

Avoid taking Cefditoren pivoxil at the exact same time you take any kind of stomach acid reducer or antacid.

Antibiotic medications may cause bacteria, which can indicate a new infection. Call your doctor if you have watery or bloody diarrhea. Don't use any medication to treat the diarrhea unless you're told to do so by your doctor.


Drug interactions can alter how your drugs work or up your risk for severe side effects. This article doesn't contain all the potential drug interactions. Have a list of all products you're currently using, such as prescription and nonprescription drugs, herbal products, mineral, and vitamin supplements. Share this list with your pharmacist and physician. Don't change, stop, or start the dose of any drugs without physician's knowledge.

Some products that could interact with Cefditoren pivoxil include: medicines that reduce stomach acid (for example antacids and H2 blockers like ranitidine).

While most antibiotic medications are not likely to affect hormonal methods of birth control like pills, ring, or patch, some antibiotics (e.g. rifabutin and rifampin) can reduce their effectiveness. This may lead to pregnancy. If you're using a hormonal birth control method, ask your healthcare professional for more information.

Cefditoren pivoxil may interfere with some lab tests (e.g. Coombs' test, and some urine glucose (sugar) tests), potentially producing false tests results. Be sure to let all your doctors and lab staff personnel know you use Cefditoren pivoxil.

Using Cefditoren pivoxil with any of these drugs may increase your risk for certain effects, but taking both drugs could be your best option for treatment. If your doctor prescribes both medicines, he or she may change your dose, or how frequently you take one or both medications.

  • Probenecid
  • Calcium Carbonate
  • Magaldrate
  • Famotidine
  • Magnesium Oxide
  • Aluminum Carbonate, Basic
  • Aluminum Phosphate
  • Dihydroxyaluminum Aminoacetate
  • Aluminum Hydroxide
  • Magnesium Hydroxide
  • Magnesium Carbonate
  • Dihydroxyaluminum Sodium Carbonate
  • Magnesium Trisilicate


If your symptoms don't improve shortly or they get worse, see your doctor.

In some patients, Spectracef may cause diarrhea. If the diarrhea is severe, it could indicate a severe side effect. Don't use any diarrhea medication without first consulting your doctor. Diarrhea medications can worsen your diarrhea or make it persist. If you've got any questions about diarrhea or mild diarrhea persists or becomes worse, see your healthcare giver at once.

Cefditoren pivoxil only helps fight bacteria, so it doesn't work against viral infections like flu and common cold.

Make sure to use Spectracef for the entire course of treatment, otherwise the medication may not help to get rid of your infection completely. Also, the bacteria could develop some resistance to Cefditoren pivoxil or other medications. This could make your infection more difficult to treat later on.

Repeated or long-term use of Spectracef may lead to another infection. If symptoms of another infection occur, please tell your doctor. You may need a new medicine to treat this.

Mild diarrhea is quite common when an antibiotic medication is used. But in rare cases, a more serious kind of diarrhea (pseudomembranous colitis) can occur. This may occur while you're using the antibiotic medication or within months after you discontinue the medication. Contact your doctor at once if stomach cramps or pain, bloody stools, or diarrhea occurs. Don't treat your diarrhea without first consulting your doctor.

Don't use Cefditoren pivoxil for longer than instructed without consulting your doctor first.

Don't take a live vaccine (for example typhoid vaccine) when you're using Cefditoren pivoxil. Consult your doctor before you take any vaccine.

For diabetes patients, Spectracef medication may affect their blood sugar. Make sure to closely monitor your blood sugar levels. Spectracef may also make some tests (e.g. urine glucose test) produce false results. Ask your physician before you alter your dose of diabetes medication or your diet.

Cefditoren pivoxil may affect some lab tests. Make sure your physician and the lab personnel know that you're using this medication.

Lab tests, including lung, liver, or kidney function may be done while you take Cefditoren pivoxil. These exams can be used to test for side effects or monitor your condition. Be sure to honor all of your lab and physician appointments.

Use Cefditoren carefully in older adults as they might be more vulnerable to its effects.

Cefditoren pivoxil shouldn't be used in kids younger than 12. Its effectiveness and safety in these kids hasn't been determined.

If you get pregnant, consult your physician. You'll need to talk about the merits and drawbacks of taking Spectracef while you're pregnant. It is unclear whether Spectracef is released in breast milk. If you're using Cefditoren and are breastfeeding or will be breastfeeding, please consult your pharmacist as well as your doctor. Discuss any potential risks to your little one.


Keep Cefditoren pivoxil at room temperature in its original container, tightly closed.

Protect Cefditoren pivoxil from direct light, moisture, and heat.

Don't keep expired Cefditoren pivoxil or one you no longer use.

Do not freeze Cefditoren pivoxil.

Ask your healthcare provider how any unneeded medicine should be disposed of.


The presence of certain medical conditions can affect your use of Cefditoren pivoxil. Be sure to report any other medical conditions you have to your doctor, especially Carnitine deficiency and kidney disease. For Carnitine deficiency, using Spectracef may worsen the condition. If you have kidney disease, you may need to take lower doses of Cefditoren pivoxil.

Don't take Cefditoren pivoxil if you have allergies to milk protein (this is not lactose intolerance). Talk with your physician if you're unsure of this.

You should not use Cefditoren pivoxil if you've ever had allergies to cephalosporin or penicillin antibiotic, including Omnicef, Keflex, Ceftin, Cefzil, and others. For more information, consult your doctor.

Before using Cefditoren pivoxil, report to your doctor any of your allergies to drugs (especially penicillin). Additionally, let your healthcare professional know if you have liver disease, kidney disease, or you suffer from malnutrition.

Take Cefditoren pivoxil for the whole duration prescribed by your physician. Your symptoms may improve before your infection is treated completely. This medication won't treat viral infections, including flu or the common cold.

Cefditoren pivoxil may make you have wrong results with some medical exams, including urine glucose/sugar tests. Let all your healthcare providers know that you're taking Cefditoren pivoxil.

Cefditoren pivoxil will be best absorbed if taken with food.

Avoid taking Cefditoren pivoxil at the exact same time you take a stomach acid reducer or antacid.

Antibiotic medicines may cause diarrhea, which can indicate a new infection. Call your doctor at once if you have bloody or watery diarrhea. Don't take any medication to treat diarrhea unless told to do so by your doctor.

Don't share Cefditoren pivoxil with anybody else, even if their symptoms are like yours.

Last Reviewed:
December 24, 2017
Last Updated:
April 26, 2018