Ceftazidime Injection Fortaz

Ceftazidime is in a group of drugs called cephalosporin antibiotics and is given via injection to treat different types of bacterial infections, including life-threatening or severe forms.

Overview

Ceftazidime is used in injection form to treat bacterial infections in a variety of parts of the body. It belongs to a group of antibiotics medicines known as cephalosporin. They work by preventing the growth of bacteria or killing bacteria. However, this medicine will not work for the flu, colds, other virus type infections. It is only available via prescription via your doctor and is available in the dosage form: Powder for solution.

Conditions treated

  • Bacterial Pneumonia caused by Haemophilus Influenzae
  • Skin Infection due to Serratia Bacteria
  • Bacterial Infection of the Cervix caused by E. Coli
  • Pneumonia caused by the Bacteria Enterobacter
  • Infection of a Joint caused by Staphylococcus Aureus
  • Joint Infection caused by Enterobacter Species Bacteria
  • Bone Infection caused by Pseudomonas Aeruginosa
  • Lower Respiratory Tract Infection
  • Bacterial Meningitis caused by Haemophilus Influenzae
  • Complicated Urinary Tract Infection caused by Enterobacter
  • Inflammation of the Endometrium
  • Skin Infection due to E. Coli Bacteria
  • Bacterial Blood Infection caused by Pseudomonas Aeruginosa
  • Active Pseudomonas Aeruginosa Pneumonia in Cystic Fibrosis
  • Pneumonia caused by Proteus Bacteria

Type of medicine

  • Powder for solution via injection

Side Effects

Along with the effects expected, Ceftazidime can potentially cause some unwanted side effects. Although not all of these side effects do occur, if they do, they could need medical attention. Remember you can report any side effects to the FDA.

We have listed the following side effects in terms of less common and rare. Check with a health professional or doctor urgently if any of the following side effects occur while taking ceftazidime:

Less common

  • Bloating
  • Changes in skin color
  • Itching of the genital area or vagina
  • Watery diarrhea which may also be bloody
  • Stomach cramps, abdominal pain or tenderness
  • Fever
  • Increased thirst
  • Vomiting or nausea
  • Pain during sexual intercourse
  • Pain
  • Swelling of the leg or foot
  • Swelling at the site of injection
  • Tenderness
  • Unusual tiredness or weakness
  • Thick, white vaginal discharge with a mild odor or no odor
  • White patches with diaper rash
  • Unusual weight loss
  • White patches in the throat, mouth or on the tongue

Rare

  • Bleeding gums
  • Chills
  • Back, leg or stomach pains
  • Crawling, burning, numbness, itching, prickling, "pins and needles", or tingling feelings
  • Dark urine
  • Cough
  • Difficulty with breathing
  • Dizziness
  • Difficulty with swallowing
  • Fast heartbeat
  • Headache
  • General body swelling
  • Hives
  • Itching
  • Large, hive-like swelling of the eyelids, tongue, face, lips, throat, hands, legs, sex organs or feet
  • Nosebleeds
  • Loss of appetite
  • Pale skin
  • Shortness of breath
  • Swelling or puffiness of the eyelids or around the face, eyes, tongue or lips
  • Skin rash
  • Tightness in the chest
  • Yellowing of the skin and eye
  • Sore throat
  • Wheezing

Some side effects of ceftazidime may occur that usually don't need urgent or serious medical attention. These side effects usually disappear during treatment as your body adjusts to the medicine with time. Also, your doctor or healthcare professional may be able to suggest various ways to reduce or prevent some of these side effects. Check with your health care professional if any of the following side effects continue or are bothering your day-to-day life, or if you have any questions or queries in general about them:

  • Red streaks on the skin
  • Yeast infection of vagina and vulva
  • Swelling, tenderness, or pain at the injection site
  • Diarrhea
  • Feeling like you could throw up
  • Throwing up
  • Indigestion
  • Intense abdominal pain

Dosage

The final dosage of any medication will depend on different factors such as the type of illness you are being treated for, your age, height, weight and past medical history. As a general reference, the typical dosage of Ceftazidime for adults is one gram administered via the vein or muscle every eight to twelve hours. The route and dosage should be determined by the severity of infection, the condition treated, renal function of the patient and the susceptibility of the causative organisms. If you miss a dose, use the missed dose as soon as you realize. Skip the missed dose if it's almost time for your next scheduled dose. Under no circumstances should you use extra medicine to counteract the missed dose. If you are receiving this medication at a hospital or clinic, call your doctor if you miss your appointment for the administration of the injection.

Interactions

Different drugs can interact with Ceftazidime to cause unwanted effects or serious illness. It's therefore important that you inform your doctor or health care professional of all the medications you are currently taking. This includes prescription, over-the-counter, vitamin, and herbal products and your past medical history. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Medications that are known to interact with Fortaz

Major reaction:

Chlorine vaccine: If you are currently being treated with Ceftazidime or have been treated with it within the last fourteen days, you should speak with your doctor before you receive the live cholera vaccine. This is because antibiotics like Ceftazidime can reduce the activity of the vaccine and inhibit its ability to work. Be wary.

Moderate reactions:

  • Bumetanide
  • Amikacin
  • Cyclosporine
  • Drospirenone / Ethinylestradiol
  • Chloramphenicol
  • Desogestrel / Ethinyl estradiol
  • Ethinyl estradiol
  • Drospirenone / Ethinylestradiol / levomefolate calcium
  • Ethacrynic acid
  • Indium oxyquinoline in-111
  • Furosemide
  • Gentamicin
  • Mycophenolic acid
  • Netilmicin
  • Mycophenolate mofetil
  • Neomycin
  • Kanamycin
  • Nimodipine
  • Streptomycin
  • Tobramycin
  • Mestranol/norethindrone
  • Torsemide
  • Live typhoid vaccine

There are six disease interactions with Fortaz (ceftazidime) which include:

  • Renal Dysfunction
  • Seizure Disorders
  • Colitis
  • Dialysis
  • Sodium
  • Liver Disease
  • Hypertension (High Blood Pressure) can also interact with the use of Ceftazidime

Warnings

You should not use this medication if you are allergic to Ceftazidime, or to other similar antibiotics, such as:

  • Cefadroxil (Duricef)
  • Cefaclor (Ceclor)
  • Cefdinir (Omnicef)
  • Cefazolin (Ancef)
  • Cefditoren (Spectracef)
  • Ceftibuten (Cedax)
  • Cefuroxime (Ceftin)
  • Cefprozil (Cefzil)
  • Cephalexin (Keflex)
  • Cephradine (Velosef)

Before using ceftazidime, tell your pharmacist or doctor if you are allergic to it or penicillins, or if you have any other allergies. This product could contain inactive ingredients, which can cause problems and allergic reactions. Speak to your pharmacist for further details.

To make sure you can safely use Ceftazidime, you should inform your doctor if you have any of the following conditions:

  • Kidney disease
  • If you are malnourished
  • Liver disease
  • Intestinal or stomach disorder such as colitis
  • Diabetes
  • If you are allergic to penicillin
  • Congestive heart failure
  • Cancer
  • If you have had a very recent surgery or medical emergency

Antibiotic medicines can increase your risk of having diarrhea, which could be a sign of another new infection. If you experience diarrhea that is bloody or watery, stop taking Ceftazidime and immediately get in touch with your doctor. Do not use anti-diarrhea medicine unless you have been told to by your doctor or a healthcare professional.

Pregnancy and Breastfeeding

  • Ceftazidime is under FDA pregnancy category B. This means that the use of Ceftazidime is not expected to be harmful to an unborn baby. You should inform your doctor or physician if you plan on becoming pregnant or are pregnant during the course of treatment.
  • Be aware that Ceftazidime can affect the effectiveness of birth control pills. You should discuss with your doctor about the possibility of using a non-hormone based method of birth control whilst taking Ceftazidime such as a diaphragm or condom to prevent falling pregnant whilst using Ceftazidime.
  • It is known that Ceftazidime can pass into breast milk and could potentially harm a nursing baby. Don't use this medication without informing your doctor if you are breast-feeding a baby.

How should I use ceftazidime injection (Tazicef, Fortaz)?

Ceftazidime is injected into a vein or muscle. You may be shown how to use injections at home. Do not self-inject this medicine if you don't understand fully how to give the injection and properly dispose of used syringes, needles, and other items used in the administration of the medicine.

Use exactly as prescribed by your doctor. Do not use in smaller or larger amounts or for longer periods of time other than you've been directed. Follow the directions on your prescription label.

Sometimes you may be required to mix ceftazidime with a liquid before it can be used. If you're using the injections at home, make sure you know how to store and properly mix the medication.

Use this medication for the full prescribed length of time. There is a chance that your symptoms can improve, but the infection has not completely cleared. Skipping doses can increase your risk of further infections that are resistant to other antibiotics. Ceftazidime will not successfully treat viral infections such as the cold or flu.

This medicine can cause strange results with certain lab tests for sugar (glucose) in urine. Inform your physician/doctor who treats you that you are taking Ceftazidime.

Storage

  • Store Ceftazidime room temperature away from heat and moisture
  • If your medicine was provided in a frozen form or was frozen after mixing, thaw it in a refrigerator or at room temperature. Do not warm in boiling water and a microwave. Use the medicine as soon as possible after it thaws. Do not refreeze.

Summary

When used correctly, Ceftazidime is successful in treating a variety of bacterial problems. It can only be used under the instruction of your doctor and to ensure it is successful, it's absolutely necessary that you inform your health care professional or doctor of the full list of medications you are currently taking and a full background of your medical history. There are certain illness and medications that can prohibit the use of Ceftazidime. You and your doctor will discuss whether Ceftazidime is the correct choice for you. It is not recommended during breastfeeding and can inhibit the effectiveness of birth control so extra precautions will be required during sexual relations whilst on this medication.