Ceftibuten (Oral)

Ceftibuten is a multiuse antibiotic used to treat different types of bacterial infections, including strains of Streptococcus and Pneumoniae.


Ceftibuten is a multipurpose antibiotic used to treat a variety of bacterial infections. As a third-generation cephalosporin or bactericidal, ceftibuten stops bacteria and inhibits new strains from spreading.

Unlike some other medications that have selective targets in specific regions of the body, ceftibuten treats a myriad of infections throughout the body, including bacterial otitis media, bronchitis, gastroenteritis, scarlet fever, urinary tract infections and more. Before prescribing ceftibuten for these conditions, healthcare will workers double check if the root causes are the result of the streptococcus or pneumoniae strains of bacteria, as these microorganisms are considered to be penicillin-receptive and responsive to ceftibuten treatments.

As with most antibiotics, ceftibuten is not intended for viral infections, such as the cold, flu, or chicken pox. Using this treatment for viruses is ineffective and, moreover, predisposes patients to getting a superinfection.

Ceftibuten is available under the US trade name Cedax. It can only be obtained via a prescription from a certified medical provider and is supplied in either capsule or oral liquid suspension form in a 400mg dose in capsule form and 90mg (5ml) or 180mg (5ml) oral suspension liquid form.

Condition(s) treated

  • style="font-weight: 400;">Bacterial otitis media
  • Bronchitis
  • Enteritis
  • Gastroenteritis
  • Group A beta-hemolytic streptococci
  • Pharyngitis
  • Respiratory tract infections
  • 400;">Scarlet fever
  • 400;">Tonsillitis
  • Urinary tract infections

Type of medicine

  • Cephalosporin antibiotics

Side effects

Ceftibuten, as with most medicines, could cause unwanted side effects to occur. Some are listed below.

Common side effects

One of the most prevalent side effects of taking ceftibuten is diarrhea. Most cases of diarrhea subside with time. However, if the symptoms persist and your diarrhea worsens, contact a medical provider for help. In the event that diarrhea occurs, do not take over the counter medicines to treat the symptom. Always check with a healthcare provider first to determine if any negative drug interactions could transpire.

Some other common side effects of ceftibuten include:

  • Appetite changes
  • Blood in the urine
  • Changes in stool color
  • Feeling faint or lightheaded
  • Feeling nauseous
  • Fever or chills
  • 400;">Headache
  • 400;">Hives
  • Joint pain
  • Mood dwings
  • Pale looking skin
  • Stomach pain
  • Swollen glands
  • Yellowing of the skin or eyes
  • 400;">Dehydration

To curb these effects, patients should take the medicine at predetermined times before or after meals. Read more under the warnings section below.

Rare side effects of ceftibuten

Some of the less common side effects of this medicine include:

  • Feeling congested
  • Feeling constipated
  • Inability to sleep
  • Lethargy
  • Moodiness
  • Rashes
  • Yeast infections

When to call a doctor

You should stop taking this medicine immediately and call a medical provider if any of the following symptoms occur:

  • Dips in urine output
  • Extreme drowsiness
  • Feeling confused
  • Hemorrhaging
  • Nonstop fever or chills
  • A persistent sore throat
  • Seizures
  • Severe stomach ache
  • Sudden bruising of the skin
  • Unrelenting diarrhea
  • Necrolysis


When it comes to prescribing medicines, every patient is different, and there is no one size fits all treatment. For patients' safety and optimal results, the dosage amounts for ceftibuten are often adjusted based on a range of factors, including age, BMI and more.

The following guide provides estimates of dosage amounts and should not replace the dosages you are given by a healthcare provider. Do not stop taking your medication or adjust the dose, unless advised by your primary doctor.

Average ceftibuten doses for bacterial infections:

  • Adults: 400 mg once per day for 10 days
  • Children: 12-18 years old: 400 mg once per day for 10 days
  • Children: 12 years old and under: 9 mg per kg of body weight for 10 days
  • Infants under six months of age: not recommended

The maximum dosage for both children and adults is 400 mg per day. The dosage may be adjusted in patients with a history of renal impairment as the maximum dose for this group is 100-200 mg per day.

Best practices for taking ceftibuten

To minimize the risks of side effects, most insert labels recommend a number of best practices. Firstly, ensure you take the right dosage: the oral liquid should be taken in the dosage amount prescribed, no less and no more. Remember, your doctor weighs a number of variables to keep you safe, including factoring in your age, body weight and medical history. The doctor will also note the medication strength and length of treatment before writing the order. Be sure to follow the prescribed amounts and continue the full length of treatment, even if your symptoms have cleared up.

Additionally, ceftibuten prescriptions are often supplied with a complementary syringe or medical cup, so make sure you use the tool provided in your package for the most accurate dose.

Take the medication at the right timeĀ ' in order to reduce the risk of side effects, medical specialists recommend taking the prescribed dose roughly two hours before your scheduled meal time. Alternatively, you could also take ceftibuten around 60 minutes after a full meal.

Shake the medication thoroughly before use to get an even distribution of the medicine every time. Approximately one minute is advised.

To avoid missed doses, try setting an alarm on your smartphone or computer, so that you remember to take the medicine at the same time every day for the prescribed length of treatment. If you miss do a dose, take it as soon as you remember. It is important, however, that you never stack doses in the same 24 hour window. When you do remember the missed dose, make a note of the time, and use this as a marker for what time you should take it the next day. In the event of an overdose, contact 911 immediately.


When an FDA approves a drug, continuous research is performed to evaluate its side effects, interactions and effectiveness in various groups.

Over the course of many years of prescribing ceftibuten for bacterial infections, doctors have established that specific drugs should not be used in conjunction with this medicine. These include the live cholera vaccine and warafin, a prevalent blood thinner or anticoagulant. Using either simultaneously with ceftibuten could lead to serious adverse side effects.

Other vaccines

Medical researchers also advise against prescribing ceftibuten with live BCG or typhoid vaccines, as doing so could reduce how well these work in patients.

Birth control

Women who are taking birth control in tandem with ceftibuten could possibly get pregnant, though this is rare. This is due to the fact that some antibiotics decrease how well hormonal birth control works.

Other medications on ceftibuten's watchlist

Your doctor will closely monitor you if you take the following medications:

  • Pepcid
  • Prilosec
  • Tagemet
  • Zantac


Follow the below precautions when taking ceftibuten to help keep you safe:

Patients with underlying medical issues

Patients who have specific underlying conditions should not take ceftibuten. The insert label typically warns against use if patients have or had past incidences of:

  • Diabetes
  • Kidney issues
  • Stomach inflammation

Ceftibuten could cause these conditions to worsen. In the event that treatment is still required and no safer alternatives are available, the dose may be altered.

Special warning for diabetics

This medicine in particular could cause spikes in blood sugar levels, as the liquid form contains one gram of sugar per teaspoon. Diabetics who are taking this medicine will be closely monitored.

Prescribing ceftibuten to children

In most cases, medical studies have confirmed safety for pediatric patients. However, this antibiotic is not intended for use in infants aged six months or younger.

Prescribing ceftibuten to seniors

As most senior patients are more likely to have pre-existing medical conditions, doctors will weigh their full medical histories to determine if ceftibuten is safe for use and whether modifications in the standard dose are necessary.

Prescribing ceftibuten to nursing mothers

Ceftibuten can seep into breast milk. As a result, doctors generally weigh the risk and benefits before prescribing this medicine to nursing mothers.

Prescribing ceftibuten to expectant mothers

Ceftibuten could cause harm to a fetus and is only recommended in life-threatening circumstances when no safer alternative can be provided. A doctor generally weighs the pros and cons before deciding on whether ceftibuten is the right treatment for the circumstances.

Non-stop diarrhea

Diarrhea, as mentioned earlier in this guide, is a common side effect of taking ceftibuten. One of the warning signs that medical intervention is necessary, however, is when a patient experiences unrelenting diarrhea that worsens over time.

This could be the sign of a serious condition known as clostridium difficile-associated diarrhea, which could develop during the course of treatment or even months after the initial plan is complete. If you have non-stop diarrhea within weeks of taking ceftibuten and it is accompanied by the following symptoms, seek medical help right away:

  • Blood in the stools
  • Cramping
  • Pain in the stomach

In these circumstances, do not attempt to take an over the counter pain reliever or anti-diarrhea treatment. These medicines could make the condition worse. Instead, call your medical provider or 911 for help. This could be a sign of a superinfection or antibiotic resistance.


Allergic reactions to ceftibuten are rare; however, it may be possible. Be sure to advise your doctor if you have a history of allergies, particularly any adverse reactions to a penicillin treatment. Also, pay attention to the some of the warning signs of an allergic reaction.

If any of the following symptoms occur while using ceftibuten, stop the treatment and call 911 immediately:

  • Difficulty breathing
  • Extreme dizziness
  • Severe rashes accompanied by itching
  • Sudden swelling

Completing lab work and medical tests

As ceftibuten could distort the accuracy of certain medical tests, it is important to advise healthcare workers on duty if you are taking ceftibuten and completing a new test. One common example of how ceftibuten could warp results is when patients take a urine glucose test, since the medicine contains significant amounts of glucose.


As ceftibuten is supplied in two different forms, capsule and oral liquid suspension, the rules governing storage are somewhat different.

For capsule forms of ceftibuten, store at room temperature at 36 to 77 degrees F and out of direct heat or sunlight. Be sure to keep this medicine out of the reach of children and pets. To preserve how the medicine works, never store capsules in the refrigerator.

For the oral liquid suspension form of ceftibuten, store in the refrigerator after each use. Make sure the cap is tightly sealed. Consider installing a child lock on the fridge if you have younger children in the home who can access the fridge independently.

Older children and teens should be warned against taking the medicine when storing it within their reach. Any unused portions of ceftibuten should be thrown out or discarded following a two week period. For individuals who are concerned about the ecological impacts of discarding medicines down drains, take any unused portions to a local pharmacy.


Ceftibuten is primarily used to treat bacterial infections caused by strains of streptococcus or pneumoniae bacteria. It is a versatile antibiotic that can effectively wipe out these bacteria, which cause urinary tract infections, bronchitis and tonsillitis, among other illnesses.

Ceftibuten is intended for oral use only and may be prescribed in capsule or oral liquid suspension form. In both children and adult patients, the standard prescription includes once a day use for a period of 7 to 10 days, depending on a range of factors.

Ceftibuten should be taken for the length of treatment prescribed, even if you feel better before the time is complete. It is also important for patients to note that ceftibuten, as with other antibiotics, cannot treat the cold or flu. To confirm the presence of a bacterial strain, a healthcare provider generally runs a number of tests, in addition to completing a physical exam.

To reduce the risk of side effects, patients should disclose their full medical history to their healthcare provider, including a list of all current medications being taken.

Ceftibuten is not suggested for all groups of patients. For example, this medicine could negatively affect neonates under the age of six months old. Moreover, diabetics and patients with a pre-existing kidney disease require an altered dosage in most cases.

Bacterial infections can put a real strain on how we feel. Fortunately, with a proven formula and antibiotic, such as ceftibuten, infections often clear up within days, so patients can carry on with their life, free of pain, discomfort and dangerous bacteria.