Cevimeline (Evoxac) increases saliva and sweat gland secretions in the body.
It helps treat dry mouth symptoms in people suffering from Sjogren’s syndrome. In Sjogren’s syndrome, your immune system upsets the glands that produce saliva and tears. It can also attack the joints, blood vessels, kidneys, lungs, nerves, and digestive organs.
• Dry mouth
• Cholinergic agonist
Apart from its desirable effects, Cevimeline can bring about several undesirable effects. While not all of the following effects can happen, if some occur they may require medical attention.
See your doctor straight away if you feel any of these effects while using Cevimeline.
Get emergency medical attention as soon as you can if any of these symptoms of overdose happen while taking Cevimeline:
Some Evoxac side effects may happen that normally don’t need treatment. They may disappear during treatment while you adapt to Evoxac. Moreover, your healthcare giver may recommend ways to reduce or prevent some of the effects. Consult your healthcare giver if any of these effects are troublesome, persist or you need more information about them.
The effects of certain medications may change if you use them together with other medications or herbal products. This may increase your chances of experiencing severe side effects or could make your medications not work properly. The following drug interactions may happen, but don’t always occur. Your healthcare professional can prevent or control interactions by close observation or changing how you take your medications.
To help your healthcare professionals provide you with the best medical care, make sure to tell them about all the medication products you use before commencing treatment with Cevimeline. While using Cevimeline, don’t change, stop, or adjust the dose of any other drugs you’re taking without your doctor’s permission.
• Cimetidine (Tagamet)
• Amiodarone (Pacerone, Cordarone)
• Metronidazole (Protostat, Flagyl)
• Cyclosporine (Sandimmune, Gengraf, Neoral)
• Antibiotics like Ciprofloxacin (Cipro), Azithromycin (Zithromax), Ketoconazole (Nizoral), Itraconazole (Sporanox), Erythromycin (Erythrocin, E-Mycin, Ery-Tab, E.E.S), and Clarithromycin (Biaxin)
• Antidepressants such as Sertraline (Zoloft), Escitalopram (Lexapro), Citalopram (Celexa), Paroxetine (Paxil), Fluvoxamine (Luvox), and Fluoxetine (Prozac, Sarafem)
• Asthma medications such as Terbutaline (Brethaire, Brethine), Albuterol (Proventil, Ventolin, etc.), Bitolterol (Tornalate), Epinephrine (Asthmahaler, Primatene mist inhaler, Bronkaid), Isoetharine (Bronkosol, Bronkometer), Pirbuterol (Maxair), Salmeterol (Serevent), and Metaproterenol (Alupent, Metaprel)
• Blood pressure or blood medications like Acebutolol (Sectral), Diltiazem (Cardizem, Dilacor, Tiazac), Nadolol (Corgard), Timolol (Blocadren), Carvedilol (Coreg), Labetalol (Trandate, Normodyne), Metoprolol (Toprol, Lopressor), Atenolol (Tenormin), Verapamil (Covera, Verelan, Calan, Isoptin), Sotalol (Betapace), Propranolol (Inderal, InnoPran), etc.
• HIV/AIDS medication such as Delavirdine (Rescriptor), Amprenavir (Agenerase), Nevirapine (Viramune), Saquinavir (Invirase, Fortovase), Indinavir (Crixivan), Ritonavir (Norvir), and Nelfinavir (Viracept)
These are not all the possible Cevimeline interactions. List all the medication products you take and share the list with your healthcare provider to reduce your risk for severe side effects.
Tell your healthcare professionals if you have Cevimeline allergies, or allergies to any other drugs.
Tell your pharmacist as well as your doctor what other medications (prescription and nonprescription), nutritional supplements, and vitamins you’re using or plan to use. Make sure to state any of these:
Many other medicines could also interact with Evoxac, so make sure to notify your healthcare provider about the medicines you take, even those not on this list.
If you’ll be using Cevimeline for quite a while, it’s vitally important that you be checked by your doctor at regular intervals for signs of you getting too much of the medicine.
Report to your doctor any herbal medicines you’re using, especially St John’s wort.
Tell your healthcare giver if you have glaucoma (an eye condition), asthma, and acute iritis/uveitis (irritation and swelling inside your eye). Your doctor may order you to not use Cevimeline.
Tell your healthcare provider if you’ve ever suffered or have a heart attack or chest pain, COPD (a set of lung conditions that includes emphysema and bronchitis), chronic bronchitis, gallstones, kidney stones, or heart disease.
Tell your physician if you’re having a baby, want to get pregnant, or breastfeeding. Call your doctor if you conceive while using Cevimeline.
During pregnancy, Cevimeline should be taken only when it’s really necessary. Be sure to discuss its benefits and risks with your healthcare professional.
If you’re undergoing surgery, for example, dental surgery, notify your dentist or doctor that you’re using Cevimeline.
You need to know that Cevimeline can cause vision changes, especially when there isn’t enough light or at night. Use the medicine cautiously when doing risky activities in decreased lighting or driving at night.
Alcohol or marijuana may cause more dizziness if taken with Cevimeline. Limit your intake of alcoholic drinks while using Cevimeline. If you’re using marijuana, consult your doctor.
You need to know that Cevimeline can make you sweat profusely, which may cause dehydration. Make sure to take lots of water and consult your doctor about preventing dehydration while using Cevimeline.
If your symptoms don’t ease within days or they get worse, please see your doctor at once.
Don’t use Cevimeline (Evoxac) if you have allergies to it, or if you have uncontrolled or untreated glaucoma, asthma, cholelithiasis (gallstones), heart disease, nephrolithiasis (kidney stones), other pulmonary disease, or an eye problem known as iritis or uveitis.
If you’ll be taking Evoxac for quite a while, it’s vitally important to be checked by your doctor regularly for signs of taking too much Evoxac.
If your symptoms don’t get better within days or they deteriorate, please see your doctor immediately.
Don’t share Cevimeline with other people. Keep all your regular lab and medical appointments so your doctor can check your progress or look for side effects. For more information, consult your doctor.
Some of Cevimeline side effects may impair your eyesight, especially at night. Take care if you drive or carry out any activity that needs you to see clearly.
Avoid getting dehydrated/overheated in hot weather and during exercise. Cevimeline can make you sweat a lot, and you can more easily become dehydrated while taking this medicine. Follow your doctor’s orders for the amount and type of fluids you should take.
Consult your physician before you eat grapefruit and drink its juice while using Cevimeline.
Cevimeline can also be taken for other purposes, so ask for more information from your pharmacist as well as doctor.