Chlorothiazide is a thiazide diuretic drug that is used in the treatment of fluid retention that is caused by kidney disease, severe liver disease (cirrhosis), congestive heart disease, or from treatment with a hormone or steroid medicine. It works by reducing the amount of water in the body by increasing the flow of urine which in turn reduces fluid retention. It is only available via prescription from your doctor or a healthcare professional and is available in the dosage form powder for the solution.
As with all medications, there can be a variety of side effects associated with chlorothiazide.
Inform your doctor immediately if you experience any of the following side effects when you are taking chlorothiazide:
Some side effects usually do not need urgent medical attention as they will usually improve as your body adjusts to the medicine. If you are suffering from any of the following side effects below, you can contact your doctor for advice to minimize them or ways to avoid them altogether. Remember you can report all side effects to the FDA at 1-800-FDA-1088.
Dosage requirements will differ with each individual depending on a variety of factors, including your age, sex, height and weight, what condition you are being treated for, the severity of your condition and how you reacted to the first dosage. The following dosage amounts are only acting as general guidelines. Stick to the dose that has been established by your doctor and do not change your dosage requirements without the consent of your doctor or a healthcare professional.
500 to 1000 mg once or twice daily
500 to 1000 mg once or twice daily
In the event of an overdosage, supportive and symptomatic measures should be employed. Gastric lavage should be performed or emesis should be induced. Correct dehydration, hepatic coma, electrolyte imbalance, and hypotension by established procedures. If required, give artificial respiration or oxygen for respiratory impairment.
Some medicines cannot be taken together as it can reduce the effectiveness of the medication. In some cases, two different medicines which cause a reaction still need to be taken together. In this type of situation, your doctor or physician may change your dose or take other precautions.
To minimise the risk of interactions, you need to inform your doctor or health care professional of any medications you are currently taking, including vitamins and herbal remedies. Below is a list of medications that are known to react with chlorothiazide. Inform your doctor if you are taking any of these.
Some medicines should not be used at or around the time of eating food or eating certain types of food as interactions can occur. This is also the case for using tobacco or alcohol with certain medicines. You should speak with your doctor or health care professional about the use of chlorothiazide with alcohol, food or tobacco.
The presence of other medical problems can affect the use of chlorothiazide. Inform your doctor or physician if you currently have any medical problems including the ones listed below.
Below are some of the warnings associated with taking chlorothiazide.
Inform your doctor if you have ever had any allergic or unusual reactions to chlorothiazide or any other medicines. You should also inform your doctor or physician if you suffer from any other types of allergic reactions, such as to dyes, foods, animals or even preservatives. Remember that for non-prescription products, you should always read the packaging or labels carefully.
Chlorothiazide is under pregnancy category C which means it should be used only when necessary. It's not recommended in pre-eclampsia and other pregnancy-induced hypertension.
Studies have suggested that this medication could alter milk composition or production. If an alternative drug is not prescribed, the infant should be closely monitored for adequate milk intake and side effects.
Studies have not indicated anything that would limit the usefulness of chlorothiazide in the elderly. However, older people are more likely to have age-related kidney, liver or heart problems, which may require a dose adjustment for those receiving chlorothiazide.
Appropriate studies have not been conducted on the effects of chlorothiazide and the relationship of age. Therefore, efficacy and safety have not been established.
A trained health professional or a nurse will give you this medicine. It is administered through a needle which is placed in one of your veins. Since this medication is taken in a hospital setting, you will not need to store it yourself. In general, it should be kept refrigerated when not in use and kept away from damp and moist areas.
When taken correctly chlorothiazide is successful in reducing water retention in various areas of the body. There are many medicines, drugs and other illnesses that can interact with this drug. It's therefore vital that you inform your doctor or health care professional of all the drugs you are currently taking including those that are herbal remedies or vitamins. You should also inform them of your past medical history and your family history of any illnesses. Your doctor will only give you a few doses of chlorothiazide until your condition begins to improve. They will then switch you to an oral medicine instead that works in the same way. If you raise any questions, queries or concerns about this, you should speak with your doctor. This drug is not recommended in breastfeeding mothers and there may be changes of dose for those who are pregnant. Remember to inform your doctor immediately if you fall pregnant whilst taking this medication.