Ciprofloxacin (Intravenous)

Ciprofloxacin is offered in a number of routes. Here we are going to cover the intravenous application, which is given under the brand name Cipro.


Ciprofloxacin injections are given as an intravenous medication, and they are used to treat a number of diseases including anthrax. It is most commonly used to treat anthrax after it has been inhaled by the victim. The drug treats pneumonic and septicemic plague, and it is used in a number of other applications when extremely dangerous infectious diseases are diagnosed or present.

The drug itself may be familiar to some readers because it has been featured in movies and television as a preventative measure when dealing with these dangerous diseases. The injection is to be given under the direction of a physician, and it is powerful enough that the dosage must be carefully managed by a trained medical professional.

Cipro is known as Ciprofloxacin and Cipro IV minibags in Canada. It is known purely as Cipro IV in the US, and it belongs in the drug class called the quinolones. Cipro is used to treat a number of other infections by killing the bacteria that cause them, and it will prevent the growth of bacteria that are present. However, the medication will not work for colds, flu, or viral infections. This is a drug that was created to help with the most serious infections known to the medical community.

Cipro comes with a number of stipulations that doctors must consider. They cannot simply give this drug to just anyone. They must use the lists of interactions, warnings, and side effects below to ensure that they are giving their patients the proper dosage. There are cases where it cannot be used at all because of its toxic properties, and it is up to the patient to give information that helps the doctor make this decision.

What Conditions Does It Treat?

  • Anthrax

What Type Of Medicine Is This?

  • Antibiotic.

Side Effects

Side effects occur in a number of different ways, and they differ from person to person. A general listing of side effects ensures that patients understand what could happen if they are using Cipro. Tendinitis is possible with Cipro, and tendon tears could happen when patients are on this medication. Also, tendon problems increase after the age of 60.

Those who are on steroid medications may have a risk of kidney problems, and it is possible that someone with a history of tendon problems will see an even worse reaction to this medication. Someone who has received an organ transplant may experience these same issues, and they must be forthcoming with their doctor.

Doctors must be contacted if there is bruising, swelling in the tendons, or swelling on the joints. Arm and leg pain should warrant a trip to the doctor, and the same is true if pain occurs on the back of the knee or ankle, elbow, shoulder, and/or wrist. Someone who cannot put weight on their joints must go to the doctor at once, and someone who is exercising may make these situations that much worse.

The doctor must be contacted if an adult or child experiences convulsions, anxiety, confusion, depression, phantom feelings, severe headaches, sleeping problems, and thoughts or behaviors that are simply not in line with the norm.

Allergic reactions have been known to occur with this medication, including anaphylaxis, and it could be life-threatening. A doctor should be contacted if the patient has a rash, hives, itching, hoarse voice, breathing problems, trouble swallowing, and swelling.

Skin reactions could happen, and blistering, peeling, loose skin, lesions, severe acne, sores, and ulcers are possible. The doctor must be consulted if any of these things happen, and a fever or chills may cause concern.

Anyone who has dark urine, clay-colored stools, abdomen pain, stomach pain, yellow eyes, and/or skin should ask a doctor for help. These are all signs of liver problems that must be treated at once. The injection itself could cause diarrhea, and it could be very severe. This is possible up to two months after the injection has been given, and a doctor must be consulted. The patient cannot treat their own diarrhea. They must go to the doctor for treatment because the medicines they take could actually make the diarrhea worse.

Any sort of tingling or numbness in the extremities could be something called peripheral neuropathy that needs to be handled as soon as possible. This could include a burning sensation in the extremities that precedes numbness.

It is possible that some patients could become more sensitive to sunlight, and that will include getting sunburned much more quickly. A rash or itching could occur because of sunlight exposure, and that must be handled with help from a doctor. Getting out of the light is important, and the doctor must be called if itching, rashes and skin discoloration occur.

  • A general plan for handling outdoor activity after receiving Cipro includes:
  • style="font-weight: 400;">Avoid sunlight especially during peak hours
  • Wear more clothing to cover the skin including a hat and sunglasses
  • Use sunscreen often
  • Do not tan or use sunlamps

Go to the doctor if there are any severe reactions.

It is possible that someone could become lightheaded or dizzy from using this medication, and they might have problems with alertness. They need to be sure they are ready to drive after using this medication, and someone who feels dizzy or unaware could be in great danger if they are driving.

Someone who has diabetes may have problems that they feel are advanced versions of their current symptoms. It is possible that low blood sugar could occur, and it could lead to someone passing out because of it. Anyone who has pain because of diabetes could feel it spike after using this medication, and they must ensure that they speak to a doctor as soon as possible.

Someone who is experiencing low blood sugar could also feel anxiety, have blurred vision, cold sweats, pale skin, drowsiness, intense hunger, nausea, headaches, nervous feelings, rapid heart rate, shakes, tired feelings, or weakness. It is also possible that the person may begin to act like they are drunk even if they have not been drinking.

Doctors must be consulted if any other medications are to be taken, and a new doctor must be told that Cipro has been administered recently.

The full list of side effects is as follows:

Black stools

Bleeding, itching, hives, rashes, inflammation, pain, numbness, lumps, scarring, red skin, tingling, stinging pains, warmth at the injection site, swelling, tenderness.

  • 400;">Chest pain
  • Chills
  • A cough
  • A fever
  • Difficult urination
  • Sores or ulcers on the mouth
  • Suicidal ideation
  • Bleeding and bruising
  • Tiredness or weakness
  • Cramps
  • Joint pain
  • Jaw pain
  • 400;">Back pain
  • Loose skin
  • 400;">Balance problems
  • Crawling feelings
  • Prickling feelings
  • Burning sensations
  • Skin color changes
  • Foot and leg pain
  • Chest tightness
  • Clammy skin
  • Convulsions
  • Diarrhea
  • Faintness
  • Irregular heartbeat
  • Flushed skin
  • Throbbing headaches
  • Sunlight sensitivity
  • 400;">Indigestion
  • Facial swelling
  • Light stools
  • Language problems
  • Mood changes
  • Muscle spasms
  • Vomiting
  • 400;">Neck pain
  • Puffy eyelids
  • Red eyes
  • 400;">Constipation
  • Shaky legs
  • Shortness of breath
  • Concentration problems
  • Sleeping problems
  • Trembling
  • Vomiting blood
  • Bone pain
  • Confusion about where you are
  • Increased sensitivity to touch
  • Rhythmical movement of muscles or joints
  • Feeling things or seeing and hearing things that are not there

Any side effects that occur that do not need medical attention should warrant a call to the doctor just to check in. These include:

  • Acidic stomach
  • Runny nose
  • Sneezing
  • Ringing of the ears
  • Eye pain
  • Hearing loss
  • No sense of smell
  • Breast swelling
  • White patches on the mouth


The dosage on this medicine is not always that large, but it must be administered slowly because the medicine is so toxic. The needle is inserted into a vein, and the IV bag will run slowly until it is in the bloodstream. Someone who is taking this medication must drink as many fluids as they can, and they can keep their kidneys healthy by passing extra urine during this time. Someone who does not flush their kidneys risks damaging them. Checking the medication guide will help doctors who have not worked with this drug before. Children will be given lower doses until they can be switched to the oral version of this medication.

Dosage changes based on the interactions listed below and doctors must be given leeway to change the dosage until they believe they will get the desired results. Anyone who has been given Cipro must be prepared to see their dosage change because there are many factors involved. Cipro is not a cure-all that works on the first try. It must be used with care and monitored and adjusted when necessary.


Drug interactions are a very large part of the prescription process, and it is possible that doctors will want to have an interaction occur when they are offering Cipro to their patients. The medication history of a patient must be revealed before Cipro is administered intravenously, and the number of drugs they have taken will alter the doctor's choice of dosage. The list of medications offered below represents all those that should never be allowed to interact with Cipro. Doctors have a right to change their prescription when they find someone is on these drugs. The course of treatment changes, but it is necessary because the adverse reactions could be lethal.

  • Agomelatine
  • Amifampridine
  • Amisulpride
  • Bepridil
  • Cisapride
  • Dronedarone
  • Fibanserin
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Saquinavir
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Tizandine
  • Ziprasidone

There is another class of drugs that may interact with Cipro, but it is possible that it may not. Doctors can use their discretion in these cases to prescribe and administer Cipro, and the dosage of either drug may be changed by a doctor if they believe it is necessary. It is not guaranteed that these drugs should be used with Cipro, but it is not expressly prohibited.

  • Acarbose
  • Acecainide
  • Acetohexamide
  • Alfuzosin
  • Alogliptin
  • Alosetron
  • Amiodarone
  • Amitripyline
  • Amoxapine
  • Anagrelide
  • Apomorphine
  • Aripiprazole
  • Arsenic Trioxide
  • Artemether
  • Asenapine
  • Astemizole
  • Azimilide
  • Azithromycin
  • Bendamustine
  • Benfluorex
  • Bosutinib
  • Bretylium
  • Buserelin
  • Canagliflozin
  • Chlropromazine
  • Chlorpropamide
  • 400;">Cholera Vaccine, Live
  • Cilostazol
  • Citalopram
  • Clarithromycin
  • Clomipramine
  • Clozapine
  • Crizotinib
  • Cyclobenzaprine
  • Dabrafenib
  • Dapagliflozin
  • Dasani in
  • Degarelix
  • Delamanid
  • Desipramine
  • Deslorelin
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Donepezil
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Droperidol
  • Efavirenz
  • Eliglustat
  • Eltrombopag
  • Erlotinib
  • Erythromycin
  • Escitalopram
  • Exenatide
  • Fentanyl
  • Fingolimod
  • Flecanide
  • Fluconazole
  • Fluoxetine
  • Gatifloxacin
  • Gemifloxacin
  • Glicazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Histrelin
  • Hydroxycholoquine
  • Hydroxyzine
  • Ibutilide
  • Ifosfamide
  • Iloperidone
  • Imipramine
  • Insulin
  • Insulin aspart, recombinant
  • Insulin bovine
  • Insulin deluded
  • Insulin determine
  • Insulin glaring, recombinant
  • Insulin glulisine
  • Insulin lispro, recombinant
  • Ketoconazole
  • Lapatinib
  • Leuprolide
  • Levofloxacin
  • Linaglipitin
  • Liraglutide
  • Lopinavir
  • Lumefantrine
  • Lurasidone
  • Mefloquine
  • Metformin
  • Methadone
  • Metronidazole
  • Mifepristone
  • Miglitol
  • Moricizine
  • Moxifloxacin
  • Nafarelin
  • Naloxegol
  • Nateglinide
  • Nilotinib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Olaparib
  • Ondansetron
  • Paliperidone
  • Panobinostat
  • Pasireotide
  • Pazopanib
  • Perflutren Lipid Microspheres
  • Pimavanserin
  • Pioglitazone
  • Prifenidone
  • Pitolisant
  • Pomalidomide
  • Posaconazole
  • Pramlintide
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinine
  • Quinine
  • Ranolazine
  • Rasagiline
  • Repaglinide
  • Rosiglitazone
  • Salemeterol
  • Saxagliptin
  • Sematilide
  • Sevoflurane
  • Simeprevir
  • Simvastatin
  • Sitagliptin
  • Sodium Phosphate
  • Sodium Phosphate, dibasic
  • Sodium Phosphate, monobasic
  • Solifenacin
  • Sorafenib
  • Sotalol
  • Sulpiride
  • Suntinib
  • Tacrolimus
  • Tasimelteon
  • Tedisamil
  • Telavancin
  • Telithromycin
  • Tetrabenzanine
  • Theophylline
  • Tolazamide
  • Tolbutamide
  • Toremifene
  • Trazodone
  • Trifluoperazine
  • Trimipramine
  • Triptorelin
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Vildagliptin
  • Vinflunine
  • Voriconazole
  • Warfarin
  • Zuclopenthixol

Side effects may increase when using Cipro with any drugs on the list below. This list may include a combination that is very good for the patient, but side effects could persist. The doctor must decide if it is best to prescribe both together. They might also change how often the drugs are used, depending on the needs of the patient.

  • Aceclofenac
  • Betamethasone
  • Budesonide
  • Chloroquine
  • Corticotropin
  • Cortisone
  • Cosyntropin
  • Cyclosporine
  • Deflazacort
  • Dexamethasone
  • Diclofenac
  • Dutasteride
  • Fludrocortisone
  • Fluocortolone
  • Fosphenytoin
  • Hydrocortisone
  • Itraconazole
  • Lanthanum Carbonate
  • Methylprednisolone
  • Mycophenolate Mofeil
  • Olanzapine
  • Phenytoin
  • Prednisolone
  • Prednisone
  • Probenecid
  • Rifapentine
  • Ropinirole
  • Ropivacaine
  • Sildenafil
  • Triamcnolone
  • Zolpidem

Using Cipro with caffeine will increase the risk of side effects, but it is impossible to avoid this in all situations. When someone must receive the treatment at a scheduled time, they should be asked to avoid caffeine before their treatment. Doctors may also have a preference regarding the use of alcohol or tobacco just before using this medication.

The doctor must be warned if the patient has any of the following medical conditions. These conditions could be made worse by using Cipro, and it is possible that using Cipro may not be the best treatment for someone who is suffering from one of these illnesses:

  • 400;">Bradycardia or slow heartbeat
  • Diabetes
  • Diarrhea
  • A history of heart attacks
  • Heart disease or failure
  • Heart rhythm issues or a history of such problems
  • Hypokalemia, low potassium
  • Hypomagnesemia, low magnesium
  • 400;">Liver disease
  • 400;">Epilepsy or seizures
  • 400;">Stroke or a history of strokes
  • Brain disease
  • Kidney disease
  • Organ transplant history
  • Tendon disorders
  • Severe muscle weakness

Reading though each of these lists is imperative when planning to use Cipro. The drug is extremely strong, and it must be treated with care when these medications or medical conditions are present. Patients must be forthcoming with their doctors, and they must read about the medication as much as they can.

Warnings Issued For The Drug's Use

Allergies may come into play when Cipro is used. Someone who has particular allergies cannot be given this drug, and their medical history must be checked before it is prescribed or dispensed if the patient has allergies to foods, dyes, preservatives, and animals. These allergies must be checked thoroughly as they may reduce the effectiveness of Cipro in a life-threatening situation.

Pediatric problems may limit how effective Cipro can be, and these deep portions of someone's medical history must be reviewed before Cipro is used. Cipro is seen as a last resort for children because of the high level of toxicity. Children may be given Cipro only when the medical staff believes they have no other option, and it will help prevent infection if there may have been exposure. Kidney infections are also treated with Cipro, but again, this drug must be seen as a last resort.

Geriatric patients will feel the full effects of Cipro when it is injected, but patients of this age are more likely to have heart or lung issues as related to the extreme toxicity of this drug. Tendon ruptures have been related to patients who were given Cipro at a late age, and the injection must be given with caution so as to reduce the risk of a rupture.

Studies on animals have not been used to gauge the effectiveness of Cipro in pregnant women, and similar studies have not been done on humans. Again, it must be used with extreme caution during every phase of pregnancy.

A nominal amount of risk has been recorded when a breastfeeding mother uses Cipro. This may seem a bit extreme, but it must be considered on a case by case basis.

Patients must be checked often for their progress, and they must avoid using medications such as Zanaflex while taking this medication. If a child is on Theo-Dur, parents must alert their doctor, and consuming quite a lot of caffeine in soda or coffee may be harmful.

Storage Protocols

Cipro must be stored at room temperature and not in the refrigerator. It must be kept in the original package, and it must be kept away from sources of heat or direct sunlight. It should never be kept in a bathroom or kitchen area because of this. Keep it in a closed space like a cabinet or drawer, and safely get rid of it if it has expired. This is a toxic drug that must be handled with care.

Cipro must be kept out of the hands of children, and it must be kept in a locked area where no one else could get to it. It cannot be stored where patients can get a hold of it because they are not authorized to use it themselves.


Cipro is an antibiotic drug that many people are aware of because of the Amerithrax case, and they are aware that it is very powerful. However, they might not have known just how strong it was until they read through all the guidelines that come with it. The drug is made to ensure that the anthrax and plague infections that are in the patient are killed. Because these are some of the most virulent diseases ever known to man, they must be tackled by something that is just as strong. The Cipro medication may be given in a number of ways, but this summary deals only with the intravenous method of use.

The drug is given via a needle that must be left in the vein for some time, and the patient must relax while it is given. A doctor must direct the injection in any patient, and the doctor must follow up with the patient often to ensure they are safe.

There is a long list of side effects that could occur, and someone who experiences any of these side effects must contact their doctor at once. The list of drug interactions is just as long because there are so many things that could happen due to the drug's strength. Doctors must be apprised of the medications a patient is on, and the doctor must be given enough time to make the proper dosage choice.

Cipro has a number of warnings that must abided because the drug is so toxic. This drug must be handled with care because it is a toxic substance, and it cannot be used without guidance from a doctor. It must be stored in the right environment, and it must be stored with thoughtfulness.

Cipro is something that has to be used as a last resort for many people. They should not be given Cipro purely because the doctor thinks that is the best immediate option. Certain people such as children and pregnant women or the elderly must not be given Cipro unless there is no other choice.

The drug was created to treat the plague that has spread around undeveloped countries, and it is used to treat other nasty bacteria that may grow inside the body. Cipro not only kills the bacteria, but it prevents them from growing. It is a drug that has become a mainstay in those instances where doctors must attack an illness with everything they have.