Corticosteroid (Otic Route)

Sold under the brand names Dermotic and Earsol-HC, otic corticosteroids are only available with a doctor’s prescription.

Overview:

Otic corticosteroids are cortisone-like medications that are applied in the ears to ease the swelling, redness, and itching caused by some ear problems.

The medications are available under the brand names Dermotic and Earsol-HC and come in the form of an oil and a solution.

Conditions treated:

• Inflammation of outer ear

Type of medicine:

• Corticosteroid

Side effects:

Besides its useful effects, otic corticosteroids can bring about some adverse effects. Of course, not all of the following effects can occur, but if they happen they may require medical care.

Some side effects could occur that often don’t require medical care. They may clear during treatment as you get used to the medicine. In addition, your healthcare specialist may help you with ways to prevent or relieve some of the following effects. If you have questions about the following side effects, they bother you or persist, check with your physician at once.

Less common:

  • Tarry or black stools
  • Anorexia
  • Chest pain
  • Breathing difficulties
  • Bone fractures
  • Stinging/burning of the ear
  • Reduced or blurred vision
  • Continual stomach burning or pain
  • Excess growth of hair in women
  • Flushing
  • Fainting
  • High blood pressure
  • Low blood pressure
  • Headache
  • Impotence in males
  • Frequent urination
  • Increased sweating
  • Impaired wound healing
  • Increased thirst
  • Menstrual changes
  • Irregular heartbeat
  • Muscle wasting
  • Muscle cramps
  • Nausea or vomiting
  • Seizures
  • Rapid weight gain
  • Persistent fungal ear infections
  • Vertigo
  • Stomach bloating
  • Thin fragile skin
  • Suppressed growth in kids
  • Weight loss
  • Swelling of lower legs or feet
  • Suppressed reaction to tests on skin
  • Tingling in lower legs or feet and arms

There haven’t been any other serious or common side effects experienced with this medication.

Other effects not mentioned above can occur in some people as well. If you notice them, report them to your healthcare specialist.

Dosage:

Proper use of otic corticosteroids

To apply ear drops:

Tilt the head or lie down so that the infected area faces up. If you’re an adult, pull the earlobe gently up and back to make the ear canal straight. For children, their earlobe should be pulled down and back to make the ear canal straight. Drop the medication into your ear canal. Keep your ear facing up for around five minutes to let the medication get to the base of your canal. You may gently insert a sterile piece of cotton wool into the opening of the ear to stop the medication from leaking out. In the beginning, your doctor may ask you to put more medication on the cotton wool during the day in order to moisten it.

To keep the medication germ-free as much as possible, don’t let the applicator tip or dropper touch any surface (even the ear). Keep the container closed tightly as well.

Don’t use otic corticosteroids for longer than recommended or more often than prescribed. Otherwise, you may increase your risk of side effects.

Don’t apply any leftover medication for future problems of the ear without first consulting your doctor. If you have certain types of infection, don’t use this medication. Doing so may worsen your infection.

Dosing

The dose of otic corticosteroids will vary with patients. Be sure to follow your doctor’s directions or those on the label. The information below only includes the standard doses of otic corticosteroids. If you’ve got a different dose, don’t adjust it unless your doctor instructs you otherwise.

The amount of medication you use depends on its strength. In addition, the number of times you take your doses per day, the interval between the doses, and how you long you take the medicine depends on the disorder for which you’re taking the medication.

Betamethasone—to reduce swelling, itching, and redness, adults and children should use two to three drops in their ear every two to three hours. Once your symptoms improve, your doctor may reduce your dose.

Dexamethasone—to reduce swelling, itching, and redness, adults and children should apply three to four drops in their ear two to three times daily. Once your symptoms ease, your doctor may reduce your dose.

Interactions:

Using otic corticosteroids with any of these drugs is not advisable. Your doctor may opt to not treat you with Corticosteroid otic or alter some other medications you use.

  • Live Rotavirus vaccine
  • Artemether
  • Rilpivirine
  • Desmopressin
  • Praziquantel

It’s usually not advisable to use Corticosteroid Otic with the following medications, but sometimes it may be necessary. If your doctor prescribes both medications together, he or she may change your dose or frequency of taking both or one of the medications.

  • Acemetacin
  • Aceclofenac
  • Alcuronium
  • Amtolmetin Guacil
  • Aldesleukin
  • Bupropion
  • Bufexamax
  • Bromfenac
  • Bosutinib
  • Boceprevir
  • Bemiparin
  • Conivaptan
  • Colistimethate Sodium
  • Cobicistat
  • Clonixin
  • Clarithromycin
  • Cisatracurium
  • Cidofovir
  • Choline Salicylate
  • Ceritinib
  • Celecoxib
  • Droxicam
  • Drospirenone
  • Doxorubicin Hydrochloride Liposome
  • Doxorubicin
  • Doxacurium
  • Dipyrone
  • Diflunisal
  • Dienogest
  • Diclofenac
  • Dexketoprofen
  • Dexibuprofen
  • Desogestrel
  • Decamethonium
  • Dasatinib
  • Darunavir
  • Daclatasvir
  • Etravirine
  • Etoricoxib
  • Etonogestrel
  • Etofenamate
  • Etodolac
  • Ethynodiol
  • Ethinyl Estradiol
  • Ethacrynic Acid
  • Estradiol
  • Enzalutamide
  • Elvitegravir
  • Efavirenz
  • Furosemide
  • Foscarnet
  • Fosamprenavir
  • Flurbiprofen
  • Flufenamic Acid
  • Floctafenine
  • Feprazone
  • Fepradinol
  • Fenoprofen
  • Felbinac
  • Fazadinium
  • Ixabepilone
  • Indomethacin
  • Idelalisib
  • Ibuprofen
  • Ketorolac
  • Ketoprofen
  • Lumiracoxib
  • Loxoprofen
  • Lornoxicam
  • Levonorgestrel
  • Lapatinib
  • Morniflumate
  • Mivacurium
  • Metocurine
  • Mestranol
  • Meloxicam
  • Mefenamic Acid
  • Meclofenamate
  • Norgestrel
  • Norgestimate
  • Norethindrone
  • Nimodipine
  • Nimesulide Beta Cyclodextrin
  • Nimesulide
  • Nilotinib
  • Niflumic Acid
  • Nifedipine
  • Nevirapine
  • Nepafenac
  • Naproxen
  • Nadroparin
  • Nabumetone
  • Oxyphenbutazone
  • Oxaprozin
  • Olaparib
  • Proquazone
  • Propyphenazone
  • Proglumetacin
  • Pranoprofen
  • Pixantrone
  • Piroxicam
  • Piperaquine
  • Pipecuronium
  • Piketoprofen
  • Phenylbutazone
  • Parecoxib
  • Pancuronium
  • Romidepsin
  • Rofecoxib
  • Rocuronium
  • Ritonavir
  • Sunitib
  • Sulindac
  • Sorafenib
  • Sodium Salicylate
  • Saquinavir
  • Salsalate
  • Salicylic Acid
  • Tubocurarine
  • Tolmetin
  • Tolfenamic Acid
  • Ticagrelor
  • Tiaprofenic Acid
  • Thalidomide
  • Tenoxicam
  • Telaprevir
  • Tacrolimus
  • Vortioxetine
  • Vincristine Sulfate Liposome
  • Vecuronium
  • Valdecoxib
  • Ulipristal

It’s usually not advisable to use Corticosteroid otic with any of these medications as it may increase your risk of certain side effects. However, using both medications could be your best option for treatment. If your doctor prescribes both medicines, he or she may change how often you take one or both medicines or adjust your dose.

  • Atracurium
  • Aspirin
  • Aprepitant
  • Aminoglutethimide
  • Alcuronium
  • Caspofungin
  • Bumetanide
  • Fluindione
  • Fosphenytoin
  • Fosaprepitant
  • Gallamine
  • Licorice
  • Hexafluorenium
  • Netupitant
  • Metocurine
  • Rifapentine
  • Rifampin
  • Phenytoin
  • Phenobarbital
  • Pancuronium
  • Ospemifene
  • Warfarin
  • Vecuronium
  • Saiboku-To

Interactions with food, alcohol, or tobacco—certain medications shouldn’t be used at meal times or when eating certain foods as interactions could occur. Also, interactions may occur if you consume tobacco or alcohol with certain medicines. Discuss with your physician the use of Corticosteroid otic with food, alcohol, or cigarettes.

Warnings:

Here some things to consider before using Corticosteroid otic:

Allergies—before using Corticosteroid otic, let your healthcare professional know if you’ve ever had any allergic or unusual reaction to medications in this class or any other medications. Also let your healthcare specialist know if you’ve got any other kinds of allergies, including allergies to foods, animals, preservatives, or dyes. For nonprescription medicinal products, please check the ingredients on the package or label carefully.

Pregnancy—there have been no studies done on the use of otic corticosteroids in pregnant women. In animal studies, however, these medications have been proven to lead to birth defects. Before you use this medication, be sure to notify your healthcare professional if you’re expecting or if you might get pregnant.

Breastfeeding—otic corticosteroids get into human milk. Make sure to discuss the benefits as well as risks of this medication with your doctor.

Pediatric—there is no specific data available about Corticosteroid otic use in kids. Kids born to women using otic corticosteroids during pregnancy should be checked for hypoadrenalism (low blood pressure, weakness, and anorexia) as well as growth.

Geriatric—while there is no specific data available about otic corticosteroid use in older adults, these medications aren’t expected to trigger different problems or side effects in the elderly than they’d do in younger persons.

Interactions with drugs—while certain drugs shouldn’t be combined in the treatment of any medical condition, in some cases two different drugs can be taken together regardless of whether an interaction could occur. In such cases, your healthcare specialist may want to adjust your dose or issue other precautions. Tell your healthcare specialist if you’re using other medications (i.e. prescription or nonprescription) while taking Corticosteroid otic.

Other medical conditions—the existence of certain medical conditions can affect your use of otic corticosteroids. Be sure to tell your healthcare professional if you suffer from any other medical conditions, especially:

• Diabetes mellitus (type 2 diabetes)
• Fungal infections
• Viral infections
• Tuberculosis
• Epilepsy—using this medication may worsen your epilepsy
• Chronic otitis media
• Glaucoma
• Osteoporosis—otic corticosteroids may increase your risk for bone fractures.
• Any other ear condition or infection or a history of the same—otic corticosteroids may cause new infections or worsen existing ones.
• Heart disease—blood pressure changes and irregular heartbeat are highly likely to occur.
• Punctured eardrum—taking otic corticosteroids while your eardrum is punctured may damage your ear.

While you’re getting treatment with Corticosteroid otic, and after you complete the treatment, don’t have any vaccinations (immunizations) without your physician’s knowledge. Otic corticosteroids may weaken your body’s resistance, possibly putting you at risk of getting the infection the vaccination is supposed to prevent.

In addition, other people living with you should not have had oral polio vaccine recently or should not take it now. There is a possibility that they might infect you with the polio virus. Also, avoid other people who have had oral polio vaccine. Stay away from them, and don’t stay with them in a room for too long. If you can’t observe these precautions, consider putting on a protective mask that covers your mouth and nose.

Storage:

  • Keep otic corticosteroids out of children’s reach.
  • Keep the medication at room temperature.
  • Keep the medication in a sealed container, away from direct light, moisture, and heat.
  • Keep otic corticosteroids from freezing.
  • Don’t keep out of date otic corticosteroids or medicines you no longer use.

Summary:

Take any missed dose as soon as you can. If your next dose is approaching, skip the one you missed and return to your usual dosing schedule. Never take double doses.

  • If you use too much Corticosteroid otic, look for emergency medical attention.
  • There aren’t any know restrictions on drinks, food, or activities while you’re using Corticosteroid otic, unless otherwise instructed by your healthcare professional.
  • If your medical condition becomes worse, or it doesn’t get better within five to seven days, please see your doctor straight away.
  • This medication may be taken for other reasons. For more information, ask your doctor.