Cromolyn (Ophthalmic route)

Cromolyn ophthalmic solution is used to treat a variety of eye conditions caused by allergic reaction, and is prescribed for both children and adults.

Overview

Cromolyn is used to treat eye disorders that occur as a result of allergies. It is administered as an ophthalmic solution and is only available by prescription from your doctor. This medication is used to treat eye conditions in both children and adults. It is important to tell your doctor about any allergies you may have before starting treatment with this solutions. In some cases, patients have been known to have an allergic reaction which requires immediate medical treatment. This is especially important if you have allergies to dye, food, animals, or preservatives.

Cromolyn solution is a sterile application containing 4% cromolyn sodium, 0.1% edetate disodium, purified water, and trace amounts of hydrochloric acid and/or sodium hydroxide to stabilize and adjust the PH. It contains benzalkonium chloride as a preservative. Cromolyn solution works by inhibiting histamine release from the mast cell.

This solution reduces swelling and other symptoms associated with allergies such as redness, burning, watering, and light sensitivity. This solution is meant for use in patients who are four years of age and older. Allow up to six weeks for your symptoms to improve. When administering this medication, do not touch the tip of the bottle to your eye. This may contaminate the solution. Discard the solution if you notice that it has changed color or has particles in it. If your symptoms do not improve after six weeks, you should ask your doctor about other treatment options.

Condition treated

  • Eye allergies

Type of medicine

  • Anti-histamines ophthalmic solution

Side Effects

This medication can cause unwanted side effects ranging from mild to severe. If you experience any side effects from this solution, you should inform your doctor immediately to avoid harm to your eye or possible allergic reaction. If you do experience a severe allergic reaction to this medication, you should seek emergency medical assistance. Do not use this solution if you are allergic to any of the ingredients of cromolyn ophthalmic solution.

Rare side effects:

  • Redness or a rash around the eye
  • In some cases, an individual will either be allergic to the ingredients or not tolerate the medication well, which, in turn, may cause redness or a rash around the eyes. Contact your doctor as you may require immediate medical attention. Do not try to use other ophthalmic products to treat this side effect.
  • Swelling of the membrane covering the white of the eye
  • This rare side effect should be addressed as soon as you notice the swelling. Failing to seek medical attention may prove harmful to the eye.
  • Redness of the white part of the eye

If you experience redness of the white part of the eye, you may be intolerant or allergic to one or more of the ingredients on the ophthalmic solution. Consult your doctor and inquire about alternative treatment options.

Styes

A stye, or an irritated raised spot on the rim of the eye, may be a rare side effect of this medication. Tell your doctor and learn how to properly treat a stye. You may need to use another medication.

Developing eye irritation

If you notice slight irritation that progresses with use of cromolyn, you may need to change your course of treatment. You may have an allergy or an intolerance to one or more of the ingredients in the solution.

Less common side effects

Watering

In some instance, this solution may cause some individuals to have watery eyes after use. If this condition continues, you should tell your doctor and discuss your options.

Itching of the eye

Some people who use this product may notice they develop itching of the eye with use. This is a sign of an allergic reaction and requires attention.

Dryness of the eye

In some rare instances, this solution causes dryness of the eye. You should ask your doctor if there are any remedies you can use to help relieve this side effect. Your doctor may choose to change your course of treatment if necessary.

Puffiness around the eye

If you notice any puffiness or swelling around the eye, you may either be having an allergic reaction, an intolerance, or you may be developing an underlying medical condition. Alert your doctor immediately and discuss your treatment options.

Common side effects

Burning or stinging

Many people who use cromolyn report having temporary burning or stinging when the drops are initially administered. This is a common reaction and is not dangerous and usually goes away within a few minutes after using the drops.

Dosage

The adult dose for allergic conjunctivitis is one to two drops in both eyes four to six times per day. The symptoms should subside anywhere from a few days into treatment, up until six weeks. This dose is also used to treat vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. In most cases, this dose is also recommended for pediatric cases. Do not change your dose or quit using this solution without the consent of your doctor. If you feel you require a dose adjustment, you should discuss it with your doctor. Always use this medication as directed and report any changes in your condition. There are not necessary dose adjustments required for liver conditions or renal impairment.

Interactions

Contact lenses

Do not wear contact lenses while you are taking this course of treatment because it could cause irritation or possible damage to your eye if exposed to infection.

Other eye medications

You should not use other eye medication while using cromolyn unless you get approval from your doctor.

Warnings

Before beginning treatment with cromolyn, you should tell your doctor about any medical conditions you have and relay information about any allergies. If you are allergic to cromolyn or any of the other components of the solution, you should begin treatment with a different medication. If you are nursing, you should inform your doctor before beginning the treatment process. Do not touch the container or the tip of the dispenser because it could cause contamination and may further damage or irritate your eye. Do not share this medication with anyone else because you run the risk of cross-contamination and can cause further irritation or damage to your eye. Do not wear contact lenses while you are using this solution because it could make your condition worse and possibly cause irritation and damage to your eye. Report any side effects or unusual reaction to your doctor immediately to help avoid damage to your eye or the appearance of additional side effects.

Storage

Keep this solution in the original dispenser bottle that it came in. The solution is sterile when you receive it and should not be tampered with or mixed with any other medication or solution. Do not let the tip of the applicator come in contact with your body and make sure to keep it out of the reach of children and pets. The solution should not be stored near heat or light. If the solution expires, you should properly dispose of it and inquire about getting another prescription. Do not puncture or alter the bottle, because it will cause contamination of the sterile solution which can potentially harm your eye.

Summary

Cromolyn is an ophthalmic solution which is used to various eye conditions which are caused by allergies. This solution is used to treat both children and adults. Before beginning this course of treatment, you should tell your doctor about any allergies you may have. In some rare cases, this solution can cause anaphylaxis, which is a life-threatening condition caused by an allergic reaction. This solution is sterile and the bottle containing the solution should not be touched by your eye. If the solution changes color or has particles in it, you should discard it and inquire about a new prescription. This solution is meant to treat individuals who are four years of age and older. This medication appears to be safe for pregnant mothers to use under the supervision of their doctor.

Cromolyn works by blocking the production of histamines in the eye that causes swelling, redness, watering, and other allergy symptoms. Use this solution as directed by your physician and do not stop taking this product until the specified time frame has passed. Usually, people see results within six weeks. If you don't notice an improvement after six weeks, you should pursue a different treatment.

Do not use this medication if it is expired. Keep your container in an area away from direct sunlight and heat. Always replace the cap to help avoid contamination of the sterile solution. Do not use this product on children under the age of four years.