Eflornithine (Topical)


Some hormonal conditions in women can cause the growth of dark or thick facial hair, known as hirsutism. Hirsutism may also be a side effect of using some drugs. It happens either due to the increased production of testosterone (the male sex hormone) or due to the skin becoming more sensitive to testosterone.

When you apply Eflornithine cream to the skin, it works by interfering with the function of a hair follicles' enzyme which helps with the growth of hair. Eflornithine cream may be used together with laser treatment to help lower the rate of growth of facial hair in ladies with this problem.

Eflornithine cream will help treat your condition as well as improve your appearance. It may also be applied for other purposes not mentioned in this article.

Conditions Treated

  • Increased female facial hair

Type Of Medicine

  • Hair growth retardant

Side Effects

Tingling, stinging, burning and redness of skin can occur. If you have these symptoms and they worsen or persist, tell your doctor straight away.

Remember that your healthcare specialist has prescribed Eflornithine cream because he/she has concluded that the medication provides more benefits compared with the chances of side effects. The majority of people using Eflornithine usually don't suffer serious side effects.

Tell your healthcare specialist promptly if you suffer any of the following unlikely but serious effects:

This medication rarely brings on a severe allergic reaction. However, get medical care straight away if you develop any signs/symptoms of a severe allergic reaction, such as rash, troubled breathing, severe dizziness and swelling or itching (especially of the throat/tongue/face).

This isn't a comprehensive list of potential Eflornithine cream side effects. If you develop other different side effects, call up your physician or pharmacist.

Contact your physician for advice about Eflornithine side effects. You can also inform the FDA about the side effects at www.fda.gov/medwatch or 1-800-FDA-1088.


Apply Eflornithine cream (Vaniqa) exactly as instructed by your physician. If there's something you don't understand about the instructions, seek clarification from your doctor, nurse or pharmacist.

Eflornithine cream doesn't œcure  or permanently get rid of undesirable facial hair. It isn't a depilatory (hair remover). You must continue using your present hair removal methods. This medication will help treat your condition as well as enhance your appearance.

Eflornithine cream is only used externally.

Eflornithine cream is normally applied two times a day, at least eight hours apart. It can also be applied as instructed by your doctor. Wash your hands prior to and after every use of Eflornithine cream.

Remove any existing facial hair using your present hair removal methods. After removing the hair, wait at least five minutes before you apply this medication. Apply a thin Eflornithine topical layer to the areas affected on your face as well as nearby areas affected under the chin. Rub the cream in thoroughly.

After applying Eflornithine cream, you may use cosmetics or sunscreen but you'll need to wait a while to let the cream be absorbed before you apply them.

Don't wash the areas treated for at least four hours after applying Eflornithine cream.

Avoid getting Eflornithine cream in your mouth, nose or eyes. If this happens, wash the affected area with some water. If Eflornithine cream gets in the eyes, thoroughly rinse them with water and call up your physician.

Eflornithine cream may temporarily cause redness, burning, tingling, stinging or rash, especially if it's used on irritated or broken skin. If you suffer irritation, apply this cream only once daily. If irritation persists, stop applying this cream and immediately call your doctor.

Continue to apply Eflornithine cream even if you don't immediately see results. The decrease in facial hair happens gradually. You may see improvement as early as four to eight weeks of Eflornithine treatment, but it could take longer in certain people. If you don't see any improvement after six months of using Eflornithine, you should discontinue using it. Hair growth may get back to the levels before treatment, about eight weeks after you discontinue treatment with Eflornithine.

If you've missed an Eflornithine dose, skip it and wait until the next time to apply the cream. Don't use double doses of Eflornithine cream to try to compensate for doses you have missed.

It's unlikely that an Eflornithine overdose will occur. If you have ingested this cream, or you suspect that there has been an overdose, be sure to contact your poison control agency, doctor or emergency room immediately for medical advice.


Your pharmacist or physician may already know any possible medication interactions and can be checking on you for them. Please don't stop, start or adjust the dose of any drug before consulting your pharmacist or doctor first.

Before you use Eflornithine cream, let your pharmacist and doctor know about all sorts of medications (prescription and nonprescription), as well as herbal products you use, especially any hair removal or skin care products.

This section does not include all potential interactions. Thus, before using Eflornithine cream, let your pharmacist and doctor know about all the products you're using. Have a list of all medications you're taking, and be sure to give your pharmacist and doctor this list.


Before deciding to use a drug, you must weigh its possible risks against its possible benefits. You and your physician will make this decision. Before you use Eflornithine cream, you should consider the following points:

Allergies - If you've ever suffered any allergic or abnormal reaction to Eflornithine cream or any other drugs, tell your doctor. In addition, tell your healthcare specialist if you've got any other kinds of allergies, like allergies to animals, foods, preservatives or dyes. For nonprescription products, please check the package or label ingredients carefully.

Children - There isn't any specific data to compare the application of Eflornithine cream in kids younger than 12 with application in other age sets. However, this medication isn't expected to bring about different problems or side effects in older kids than it causes in adults.

Eflornithine cream is not recommended for use by anybody under the age of 12.

Older adults - This cream has been examined and hasn't been shown to cause different problems or side effects in older adults than it causes in younger adults.

Pregnancy - Make sure to tell your physician if you plan to get pregnant or are pregnant. It's not known whether Eflornithine cream will affect the fetus.

Breastfeeding - It is unclear whether Eflornithine cream gets into the human milk. It's also unknown whether the medicine could affect a nursing baby. Please tell your physician if you're breastfeeding and are using Eflornithine.

If skin irritation happens, decrease the frequency of treatment with this drug. If irritation persists, stop applying the cream and immediately contact your doctor.

If you don't notice any improvement after SIX months of Eflornithine treatment, stop applying the cream and give your physician a call. If your condition deteriorates while using Eflornithine cream, stop using it and call up your physician. Unless you're told otherwise by your doctor, keep taking your usual diet.


  • Store Eflornithine cream at room temperature (25 degrees Celsius).
  • Keep Eflornithine away from moisture and light.
  • You can briefly store Eflornithine cream at 15 to 30 degrees Celsius.
  • Keep Eflornithine cream away from your pets and kids.
  • Don't freeze Eflornithine cream.
  • Don't use Eflornithine cream after it has expired.
  • Don't flush Eflornithine cream down your toilet or pour it into the drain unless you're directed to do so.
  • Properly discard Eflornithine cream when you don't use it anymore or it's expired.
  • Contact your nearest waste disposal service or pharmacist for more information about how to dispose of this medication safely.


Eflornithine cream isn't a depilatory (hair remover). You may have to keep using your regular hair removal methods. Ways to get rid of undesirable facial hair include shaving, waxing, plucking, electrolysis, laser treatments and hair removal creams. Your doctor will tell you which of these techniques are best to try alongside Eflornithine cream.

If you need to use makeup on skin areas you've applied Eflornithine cream, you can do that, but be sure to wait at least 5 minutes after Eflornithine application to do so. It's vital to apply this cream on a regular basis. It may take approximately eight weeks for you to start seeing the benefit of applying this cream. If there's no improvement after four months of applying Eflornithine cream, please talk about this with the doctor who will evaluate your treatment.

Don't share Eflornithine cream with others. Your pharmacist can provide you with extra information about Eflornithine cream that you can read, which is written for healthcare professionals.

Follow all the instructions on your medication package and label. Tell all your healthcare specialists about all your allergies, all your medical issues, and all medications you take. Don't miss any appointments with your doctor.