Ergoloid Mesylates (Oral, Sublingual)

Overview

Many patients that suffer from Alzheimer's disease or have had multiple small strokes can experience negative changes in their behavior and mood that can be eased by taking ergoloid mesylates. This prescription-only medication is not effective in the treatment of migraines in the way that other ergot alkaloids like ergotamine and methysergide are. It is unclear exactly how ergoloid mesylates affect the body and brain, but it is effective in lessening the mood and behavior changes that occur in some patients.

It is possible to overdose on ergoloid mesylates and patients that are taking this drug must familiarize themselves with the signs and symptoms of possible overdose and seek immediate emergency medical treatment should any of them occur. If you are taking other medications or are suffering from other conditions, it is important to inform your doctor of all of the medications that you are taking and what ailment they are treating. There are a number of medications and conditions that can make it more difficult to treat mood and behavior changes with ergoloid mesylates.

This medication can cause unwanted side effects, and may also take more than a few dosages to be effective. Due to this, your doctor may order regular blood tests or utilize other diagnostic tools to monitor the effectiveness of the treatment as well as monitor your system for the occurrence of unwanted side effects.

Inform your doctor of any changes that occur to your overall health or of any changes to the medications that you are taking, or how you are taking them.

Conditions Treated

  • Mood and behavioral changes in Alzheimer's patients and those that have experienced multiple small strokes

Type Of Medicine

  • Ergot alkaloid

Side Effects

There are certain side effects that can occur in patients that are taking ergot alkaloid that will require further medical attention. Be sure to notify your doctor as soon as possible if you experience any of the symptoms outlined below.

Less likely and rare in occurrence:

  • Slow pulse
  • Skin rash
  • Dizziness and lightheadedness
  • Drowsiness

It is important that patients are aware of the signs and symptoms of ergoloid mesylates overdose:

  • Blurred vision
  • Nausea, with or without vomiting
  • Stuffy nose
  • Fainting
  • Stomach cramps
  • Headaches
  • Loss of appetite
  • Dizziness
  • Flushing

Familiarize yourself with the signs of overdose and seek immediate emergency treatment if you experience any of them.

Additionally, there are certain side effects that can occur when the body is adjusting to the introduction of ergoloid mesylates into the system. This group of side effects will likely go away on their own and should not be cause for alarm. However, if they linger for more than a few days or worsen, it is always best practice to consult with your prescribing physician to ensure that further medical attention is not necessary.

Less likely and rare in occurrence:

-Soreness in the tongue area when taking the sublingual tablets

While this list is comprehensive, there remains a possibility that certain symptoms may occur that are not listed here. If you experience any side effects that are of concern to you, contact your physician for further guidance.

Dosage

The dosage guidelines for ergoloid mesylates that are outlined below represent the typical amount and frequency for taking the medication, but if your doctor has prescribed another amount, or has directed you to take the medication with a varying frequency, it is important to follow those instructions. Be sure to take the medication for the entire course of treatment, do not stop taking ergoloid mesylates without first consulting with the prescribing physician.

If you have been directed to take the sublingual tablets, there are a few important things to keep in mind. Do not ever chew, swallow, or otherwise ingest the tablet. Allow the pill to dissolve underneath the tongue without hurrying the process. The medication is more effective if you allow it to be absorbed through the mouth. It is important that patients do not smoke while they are waiting for the pill to dissolve. Do not eat or drink while the tablet is in the mouth, and wait until the medication has been fully absorbed before doing so.

There may be differences between the amount of medication that the patient is prescribed and the typical dosage due to your age, weight and severity of the condition that is being treated.

For patients that are taking any of the oral delivery methods, whether it be sublingual, an oral solution, capsule or tablet, the dosage is typically the same: one to two milligrams taken by mouth three times each day. Your doctor will provide specific information relating to the amount of time between each dose, as it may vary from patient to patient.

Major Drug Interactions:

There are certain drugs that should not be taken together due to the negative effects that the combination can cause. If you are currently taking one of the medications that are listed below, your doctor may alter the dosage that you take of one or both of the drugs or may switch medications completely. Be sure to discuss your complete medical history as well as all of your current medications prior to taking ergoloid mesylates.

Due to the fact that it is not recommended to take the drugs listed below concurrently with ergoloid mesylates, be sure to notify your doctor should you experience any unwanted side effects.

  • Almotriptan
  • Troleandomycin
  • Atazanavir
  • Spiramycin
  • Clarithromycin
  • Miokamycin
  • Roxithromycin
  • Erythromycin
  • Rizatriptan
  • Frovatriptan
  • Nelfinavir
  • Josamycin
  • Naratriptan
  • Mepartricin
  • Nefazodone
  • Ketoconazole
  • Ritonavir
  • Indinavir
  • Rokitamycin
  • Fosamprenavir
  • Saquinavir
  • Dirithromycin
  • Sumatriptan
  • Azithromycin
  • Voriconazole
  • Amprenavir
  • Zolmitriptan

If you are currently taking one of the following medications and your doctor starts you on a course of treatment with ergoloid mesylates it will likely be with altered dosage guidelines, which should be followed explicitly.

  • Fluconazole
  • Telithromycin
  • Fluvoxamine

Patients that are taking Delavirdine, as well as ergoloid mesylates, may be susceptible to an increased likelihood of the occurrence of some side effects. If you are taking ergoloid mesylates with the following, be sure to inform your doctor of any complications that you may experience.

  • Delavirdine

The drugs listed above represent a comprehensive list of possible negative interactions, but you may have a reaction while taking medications that are not included. Inform your doctor of all of your medications and of any changes that may occur while you are taking ergoloid mesylates.

Be sure to review your complete medical history with your doctor prior to starting ergoloid mesylates as there are some conditions that can create negative effects. If you suffer from any of the following it is important that you stay in close communication with your physician and let them know of any side effects that you encounter.

  • Other mental problems
  • Slow heartbeat
  • Liver disease
  • Low blood pressure

Warnings

Your doctor may order blood or other diagnostic tests while you are taking ergoloid mesylates. It is important to keep all appointments and undergo all tests that are ordered by your physician. These tests will allow them to monitor the effectiveness of the medication and also screen for the presence of any unwanted side effects.

Storage

It is always best to keep all medications in their original packaging for storage. Do not expose ergoloid mesylates to direct light, excessive heat or cold, and do not freeze. Store in a dry location that is free of moisture and is at room temperature.

Keep this and all medications out of the reach of children.

If you have excess medication at the conclusion of your course of treatment, consult with your physician or pharmacist on the most appropriate way to dispose of unused or expired medications.

Summary

Many patients that suffer from Alzheimer's disease or have had multiple small strokes can experience negative changes in their behavior and mood that can be eased by taking ergoloid mesylates. This prescription-only medication is not effective in the treatment of migraines in the way that other ergot alkaloids like ergotamine and methysergide are. It is unclear exactly how ergoloid mesylates affect the body and brain, but is effective in lessening the mood and behavior changes that occur in some patients.

If you are prescribed this medication it is important that you communicate any changes in your overall health to your physician. As it is possible to overdose on ergoloid mesylates be sure to monitor all side effects and symptoms while taking this medication.