Erythromycin (Intravenous)

Erythromycin is an injected medication within the class macrolide antibiotics, and is used for the treatment of several diseases as well as bacterial infections in various parts of the body.


Erythromycin injection is a medication that is used for the treatment of bacterial infections in many parts of the body. Also, this injection can be used as a preventative measure for com/health/rheumatic-fever/">rheumatic fever or bacterial endocarditis, in patients where penicillin or sulfa drugs have resulted in an allergic reaction.

This medication may also be used as a treatment for Legionnaire's disease, acute pelvic inflammatory disease and diphtheria. As a medication that is under the class of macrolide antibiotics, Erythromycin functions by killing the bacteria in the human body or by preventing their growth.

This medication does not work to prevent or treat viral infections such as flu, colds and other virus-based infections.

Erythromycin is only given in a clinical environment, under the supervision of a relevant medical professional to ensure proper treatment.

Conditions Treated

  • Treatment of bacterial infections
  • Diphtheria
  • Acute pelvic inflammatory disease
  • Legionnaire's disease
  • Prevention of bacterial endocarditis and rheumatic fever

Type Of Medicine

  • Powder for solution

Side Effects

Erythromycin has some required effects that are caused by the medication itself. However, additional side effects may present themselves during treatment with this drug. These unwanted effects can range from mild discomfort to more severe conditions, and if they are present may require medical support or attention.

It is vital that you check with a medical professional as soon as you can should you experience any of the listed symptoms:

  • Yellow eyes and skin
  • Wheezing
  • Upper right abdominal or stomach pain
  • Unusual weight loss
  • Unusual tiredness or weakness
  • Tightness in the chest
  • Swelling of the feet or lower legs
  • Sores, ulcers, or white spots in the mouth or on the lips
  • Sore throat
  • Skin rash
  • Redness of the skin
  • Red, irritated eyes
  • Red skin lesions, with a purple center
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Pain
  • Nausea and vomiting
  • Light-colored stools
  • Joint or muscle pain
  • Irregular or slow heart rate
  • Irregular heartbeat recurrent
  • Increased thirst
  • Hives or welts
  • Hearing loss
  • Greatly decreased frequency of urination or amount of urine
  • General tiredness and weakness
  • Fever
  • Fast heartbeat
  • Fainting
  • Dizziness
  • Difficulty with swallowing
  • Diarrhea, watery and severe, which may also be bloody
  • Diarrhea
  • Dark urine
  • Cough
  • Chills
  • Chest pain or discomfort
  • Bloody or cloudy urine
  • Bloating
  • Blistering, peeling, or loosening of the skin
  • Abdominal or stomach cramps or tenderness

In addition to the side effects that may require some medical support or attention, Erythromycin may also result in some effects that will reduce, gradually stop or go away over the time it takes for the body to adjust to the medication. Also, a doctor may be able to provide methods and ways to reduce or prevent these side effects, should they become problematic or uncomfortable.

If you experience any of the listed side effects, check with your doctor if they continue or become persistent:

  • Weight loss
  • Loss of appetite
  • Diarrhea (mild)
  • Abdominal or stomach pain

If you wish to report any additional or unlisted side effects that you may be experiencing, you can do so by contacting the FDA directly at 1-800-FDA-1088.

As with a lot of medications, Erythromycin can trigger an allergic reaction, mainly if you have any allergies to the substances used in the medicine. Signs or symptoms of an allergic reaction to this medication can include but are not limited to severe hives, a swelling of the lips, tongue, face, or throat, and difficulty with breathing. Any of these symptoms should immediately be brought to the attention of a medical expert.


A trained medical professional will administer Erythromycin to you in a clinical, safe environment. Due to the method of administration, this is the only way in which a patient will be treated with this medication.

The dosage of this medication is entirely dependant on the advice of a doctor or similar medical professional, and the length of treatment will depend on the condition that is being treated. The following is a guideline for the duration of treatment:

  • Urogenital infections: 7 to 14 days
  • Upper respiratory infections should be treated for 7 to 10 days
  • Streptococcal diseases (such as tonsillitis or pharyngitis): at least ten days
  • Skin or soft tissue infection: 7 to 10 days
  • Primary syphilis: 14 days
  • Pneumonia: 10 to 21 days
  • Pertussis: 14 days
  • Otitis media: 10 to 14 days
  • Lymphogranuloma venereum: 21 days
  • Lyme disease: 14 to 21 days
  • Campylobacter gastroenteritis: 3 to 5 days
  • Acute pelvic inflammatory disease: 10 to 14 days


Due to the nature of individual medications and the way they can cause reactions with the chemicals within other forms of medicine, it's recommended that certain drugs are never used together. Despite this, if taking two medications that interact together has benefits that outweigh the risks, a doctor may choose to prescribe two incompatible medicines at the same time. If this is the case, a medical professional may want to either alter the dosage of your medication or suggest other precautions that you can take.

The listed interactions have been included due to their significance and relevance to Erythromycin. However, other medicines may also result in interactions. To prescribe the best possible combinations of medication, it's essential to ensure your doctor is aware of every medication you are currently taking, or have taken recently, including over the counter drugs, vitamins or herbal supplements.

Using Erythromycin with any of the listed drugs is not recommended. Based on your history and other interactions, your doctor may choose to alter your dosage or opt for a different form of treatment based on your usage of the below:

  • Ziprasidone
  • Thioridazine
  • Terfenadine
  • Sparfloxacin
  • Simvastatin
  • Saquinavir
  • Posaconazole
  • Piperaquine
  • Pimozide
  • Methysergide
  • Methylergonovine
  • Mesoridazine
  • Lovastatin
  • Lomitapide
  • Levomethadyl
  • Grepafloxacin
  • Fluconazole
  • Flibanserin
  • Ergotamine
  • Ergonovine
  • Ergoloid Mesylates
  • Dronedarone
  • Dihydroergotamine
  • Colchicine
  • Cisapride
  • Bepridil
  • Astemizole
  • Amisulpride
  • Amifampridine

Also, using Erythromycin with any of the below-listed medications is usually not a recommended method of treatment. However, this may be a requirement in some cases depending on the benefits of this treatment. If Erythromycin is prescribed alongside any of the below drugs, your doctor may decide to change your dose or the times at which you take your medications.

  • Zuclopenthixol
  • Zotepine
  • Zolmitriptan
  • Warfarin
  • Voriconazole
  • Vinflunine
  • Vincristine Sulfate Liposome
  • Vincristine
  • Vinblastine
  • Verapamil
  • Venetoclax
  • Vemurafenib
  • Vasopressin
  • Vardenafil
  • Vandetanib
  • Troleandomycin
  • Triptorelin
  • Trimipramine
  • Trimethoprim
  • Trifluoperazine
  • Trazodone
  • Toremifene
  • Topotecan
  • Tolvaptan
  • Tizanidine
  • Theophylline
  • Tetrabenazine
  • Telithromycin
  • Telavancin
  • Telaprevir
  • Tedisamil
  • Tadalafil
  • Tacrolimus
  • Sunitinib
  • Sultopride
  • Sulpiride
  • Sulfamethoxazole
  • Spiramycin
  • Sotalol
  • Sorafenib
  • Sonidegib
  • Solifenacin
  • Sodium Phosphate, Monobasic
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate
  • Simeprevir
  • Sevoflurane
  • Sertindole
  • Sematilide
  • Risperidone
  • Ranolazine
  • Quinine
  • Quinidine
  • Quetiapine
  • Protriptyline
  • Propafenone
  • Promethazine
  • Prochlorperazine
  • Procainamide
  • Probucol
  • Prajmaline
  • Pixantrone
  • Pitolisant
  • Pitavastatin
  • Pirmenol
  • Pimavanserin
  • Perflutren Lipid Microsphere
  • Pentamidine
  • Pazopanib
  • Pasireotide
  • Panobinostat
  • Paliperidone
  • Oxycodone
  • Ondansetron
  • Olaparib
  • Ofloxacin
  • Octreotide
  • Nortriptyline
  • Norfloxacin
  • Nilotinib
  • Naloxegol
  • Nafarelin
  • Moxifloxacin
  • Morphine Sulfate Liposome
  • Morphine
  • Mifepristone
  • Metronidazole
  • Mefloquine
  • Lurasidone
  • Lumefantrine
  • Lumacaftor
  • Lorcainide
  • Lopinavir
  • Lidoflazine
  • Levofloxacin
  • Leuprolide
  • Lapatinib
  • Ketoconazole
  • Ivacaftor
  • Ivabradine
  • Isradipine
  • Isoflurane
  • Imipramine
  • Iloperidone
  • Ifosfamide
  • Idelalisib
  • Ibutilide
  • Ibrutinib
  • Hydroxyzine
  • Hydroxychloroquine
  • Hydroquinidine
  • Hydrocodone
  • Histrelin
  • Halothane
  • Haloperidol
  • Halofantrine
  • Granisetron
  • Goserelin
  • Gonadorelin
  • Gemifloxacin
  • Gatifloxacin
  • Foscarnet
  • Fosaprepitant
  • Fluoxetine
  • Flecainide
  • Fingolimod
  • Fentanyl
  • Escitalopram
  • Eplerenone
  • Enflurane
  • Encainide
  • Eliglustat
  • Efavirenz
  • Droperidol
  • Doxorubicin Hydrochloride Liposome
  • Doxorubicin
  • Doxepin
  • Donepezil
  • Domperidone
  • Dolasetron
  • Dofetilide
  • Disopyramide
  • Diltiazem
  • Digoxin
  • Dibenzepin
  • Deslorelin
  • Desipramine
  • Delamanid
  • Degarelix
  • Dasatinib
  • Darunavir
  • Dabrafenib
  • Cyclobenzaprine
  • Crizotinib
  • Conivaptan
  • Cobimetinib
  • Cobicistat
  • Clozapine
  • Clomipramine
  • Clindamycin
  • Clarithromycin
  • Citalopram
  • Ciprofloxacin
  • Cilostazol
  • Cholera Vaccine, Live
  • Chlorpromazine
  • Chloroquine
  • Chloral Hydrate
  • Cerivastatin
  • Ceritinib
  • Carbamazepine
  • Buserelin
  • Brexpiprazole
  • Bretylium
  • Bosutinib
  • Bedaquiline
  • Azithromycin
  • Azimilide
  • Atorvastatin
  • Asenapine
  • Arsenic Trioxide
  • Aripiprazole
  • Aprindine
  • Aprepitant
  • Apomorphine
  • Apixaban
  • Anagrelide
  • Amoxapine
  • Amitriptyline
  • Amiodarone
  • Ajmaline
  • Afatinib
  • Acecainide

If you are prescribed to take Erythromycin while using certain medications, there may be a small or increased risk of complications or side effects as a result of drug interactions. However, in many of these cases, using these drugs in combination may be the best course of treatment for any conditions. Based on your reaction to these interactions, your doctor may choose to alter or correct your dosage over time.

  • Zafirlukast
  • Valproic Acid
  • Trimetrexate
  • Triazolam
  • Tolterodine
  • Suvorexant
  • Sirolimus
  • Sildenafil
  • Salmeterol
  • Roflumilast
  • Phenprocoumon
  • Midazolam
  • Methylprednisolone
  • Dicumarol
  • Diazepam
  • Cyclosporine
  • Buspirone
  • Budesonide
  • Bexarotene
  • Avanafil
  • Anisindione
  • Alprazolam
  • Alfentanil

In addition to the interactions caused by chemicals within contrasting medications, reactions or interactions with certain food, alcohol or tobacco may cause specific issues or interactions with many different forms of drugs. This could cause problems with taking medication at the same time as eating.

Erythromycin has no known interactions with food, alcohol or tobacco, though any side effects or interactions should be reported to your doctor.

The presence of other pre-existing medical conditions can affect the use and the effectiveness of Erythromycin. It's vital that you tell your doctor if you are currently suffering from any of the following:


If you are taking Erythromycin, it's important that you are monitored consistently and often by a medical professional to ensure that this medication has the proper effect, and if helping to treat the condition that you were prescribed this medication for. This is also a way to allow for the efficient monitoring of interactions and side effects.

If, after several weeks of treatment with Erythromycin, your symptoms or condition is not improving, it's important to talk to your doctor. If your health is becoming worse, it could be an indication that the medication is not working correctly for your condition.

If you are experiencing some of the following conditions, you may be showing symptoms of a serious liver problem as a result of taking Erythromycin:

  • Yellow eyes or skin
  • Unusual tiredness or weakness
  • Pale stools
  • Pain/tenderness in the upper stomach
  • Nausea
  • Loss of appetite
  • Dark urine

Taking Erythromycin can result in diarrhea, which can in some cases be fairly severe. This symptom can occur at any time during treatment with this medicine, but it is specifically known to occur up to two months after you stop taking this particular medication. It is important that you do not take any medication for the treatment of this condition without first consulting with a doctor, as it may worsen your condition. Any questions or concerns regarding persistent or severe diarrhea can be answered by a relevant medical professional.

In addition to causing stomach issues, Erythromycin may also cause changes in heart rhythm, including a condition known as QT prolongation. This condition can alter the way that your heart beats, and as a result, can cause side effects such as fainting or heart trouble. A fast heartbeat, pounding feeling or uneven beat should be brought to the attention of a doctor as soon as possible.

Before any medical tests, dental work or other treatments, it's important to inform your doctor that you are taking Erythromycin. Certain tests can be altered by the presence of this medication in the system. Never take additional medications that have not been prescribed by a medical professional, including over the counter medications or vitamins.


This medication is stored in a clinical environment by medical professionals, and as such is kept away from the general public.

This solution should be stored in the way directed on the packaging before use by a medical professional or doctor, and any unused medication should be disposed of appropriately.


Erythromycin is an injection medicine that is used to treat infections that are bacterial. In addition to bacterial conditions, this medication is also used to treat conditions such as diphtheria, Legionnaire's disease and acute pelvic inflammatory disease. Erythromycin belongs to a class of medicines known as macrolide antibiotics.

This drug is also used as a method to treat and to prevent conditions such as bacterial endocarditis and rheumatic fever, stopping them from occurring again in patients who have had an allergic reaction to other drugs.

This medication is only prescribed and given in a clinical setting, as it involves injecting a solution directly into the bloodstream.