Esomeprazole Strontium (Oral)

Overview

Esomeprazole Strontium reduces the quantity of acid made in the stomach.

Esomeprazole helps treat gastroesophageal reflux disease (GERD) symptoms, as well as other problems associated with too much stomach acid like Zollinger-Ellison syndrome. It's also taken to treat erosive esophagitis (esophageal damage due to excess stomach acid).

Esomeprazole Strontium may also help prevent gastric cancer resulting from infection with H. pylori (helicobacter pylori), or due to the intake of NSAIDs (non-steroidal anti-inflammatory drugs).

Esomeprazole Strontium doesn't immediately relieve symptoms of heartburn.

Esomeprazole Strontium may also be taken for other purposes not discussed in this article and is only available with a doctor's prescription.

Conditions Treated

  • Excessive stomach acid
  • Zollinger-Ellison syndrome
  • Erosive esophagitis
  • Duodenal ulcers due to H. pylori
  • Heartburn
  • Stomach ulcers due to NSAIDs intake
  • Bleeding from stomach, duodenum, esophagus

Type Of Medicine

  • Proton pump inhibitor

Side Effects

Aside from its useful effects, Esomeprazole Strontium may bring on some undesirable effects. While not all of the effects below may occur, they may require medical attention if they do.

Please see your doctor straight away if you develop any of the effects below:

Rare:

  • Cough
  • Dizziness
  • Difficulty with swallowing
  • Tarry, black, or bloody stools
  • Chest tightness or chest pain
  • Excess gas or air in the stomach
  • Shortness of breath
  • Fast heartbeat
  • Itching, hives, or skin rash
  • Unusual tiredness/weakness
  • Vomiting blood or substance that resembles coffee grounds
  • Swelling or puffiness of eyelids or area around the eyes, lips, tongue, or face
  • Discomfort or pain in the upper stomach, chest, or throat
  • Large swelling like hives on the eyelids, face, tongue, throat, lips, feet, legs, hands, or genitals
  • Incidence unknown:
  • Chills
  • Diarrhea
  • Dark-colored urine
  • Loosening, peeling, or blistering of skin
  • Headache
  • High fever
  • Sore throat
  • Trembling
  • Seizures
  • Loss of appetite
  • Joint/muscle pain
  • Light-colored stools
  • Nausea or vomiting
  • Mental/mood changes
  • Tetany (muscle spasms) or twitching
  • Yellow eyes/skin
  • Unexplained bleeding/bruising
  • Severe and watery diarrhea, which may be bloody too

Some Esomeprazole Strontium may happen that normally don't require medical intervention. These effects may clear during treatment as you adapt to Esomeprazole Strontium. In addition, your healthcare specialist may recommend ways to relieve or prevent some of the effects. Visit your healthcare specialist if any of the effects below persist, bother you, or you've got queries about them:

More common:

Passing gas

Dry mouth

Difficulty with passing stools

Rare:

  • Hiccup
  • Change in taste
  • Back pain
  • Changes in vision
  • Hearing loss
  • Fast, irregular, or pounding heartbeat or pulse
  • Slow heartbeat
  • Continuing buzzing or ringing or other unusual noise in ears

Incidence unknown:

Thinning of hair or hair loss

Breast soreness or swelling of breasts in both women and men

Other effects not listed above may also happen in some people. If you develop any other effects, make sure to see your healthcare professional.

Call your physician for advice about the above side effects. You may let the FDA know about the side effects at 1-800-FDA-1088.

Dosage

Take Esomeprazole Strontium exactly as ordered by your healthcare professional. Don't take more or less of it, don't take it for longer than prescribed, and don't take it more times than directed.

Esomeprazole Strontium comes with patient instructions and a medication guide. Please read and carefully follow the instructions. If you've got any questions, ask your physician.

Take Esomeprazole Strontium at least an hour before each meal and for the entire duration of therapy, even if you start to feel well after some days.

If you're using Esomeprazole Strontium to relieve an ulcer along with H. pylori infection, please take it with antibiotics, such as clarithromycin and amoxicillin.

To use the Esomeprazole Strontium capsule:

Swallow the whole capsule. Don't chew or crush it.

If you can't swallow the capsule, sprinkle its contents on 1 full tablespoon of applesauce.

Swallow the mixture straight away. Don't crush or chew the granules.

To take the Esomeprazole Strontium capsule with an NG (nasogastric) tube:

Empty the granules in the capsule into a 60-millimeter syringe with a catheter tip and mix with 50 millimeters of water.

Shake the syringe properly for 15 seconds.

Pour or inject the mix into the NG tube.

Put some water in the empty syringe and shake.

Flush the NG tube to rinse the whole medication into the stomach.

To use the Esomeprazole Strontium oral suspension:

Empty a 2.5 to 5 milligram packet into a tub containing 5 milliliters of water.

Empty a 10, 20, or 40 milligram packet into a tub containing 15 milliliters of water.

Stir and give it 2-3 minutes to thicken.

Stir properly and drink inside 30 minutes.

If any medication remains after drinking, be sure to add some water, stir, and then drink right away.

To use Esomeprazole Strontium oral solution with a gastric or nasogastric (NG) tube:

Add 5 milliliters of water to a syringe with a catheter tip and add 2.5 or 5 milligrams of the suspension.

Add 15 milliliters of water to a syringe with a catheter tip and add 10, 20, or 40 milligrams of the suspension.

Shake the syringe immediately and let it thicken for 2-3 minutes.

Shake the syringe once more and pour or inject the mix into the tube within half an hour.

Put 15 milliliters of water in the empty syringe and shake.

Flush the tube so that all the medicine gets into the stomach.

The Esomeprazole Strontium dose will vary with people. Follow the instructions on the label or your doctor's instructions. The information below only includes the standard Esomeprazole Strontium doses. If you have a different dose, don't adjust it unless your physician tells you to.

The quantity of Esomeprazole Strontium you use depends on its strength. In addition, the duration in which you take Esomeprazole Strontium, the dose amounts you take daily, and the time permitted between doses depend on the condition for which you're taking Esomeprazole Strontium.

For oral forms of dosage (suspension or capsules):

To prevent gastric ulcers associated with NSAIDs:

Adults should take 20 or 40 milligrams once daily for around 6 months. If necessary, your doctor can adjust your dose.

The dose and use in children must be decided by your doctor.

To relieve duodenal ulcers along with H. pylori condition:

Adults should take 40 milligrams once daily for 10 days. You should take this dose together with clarithromycin and amoxicillin. If necessary, your doctor can adjust your dose.

The dose and use in children must be decided by your doctor.

To relieve erosive esophagitis:

Adults should take 20 or 40 mg once daily for 4-8 weeks. If necessary, your doctor can adjust the dose.

Children aged 12-17 should take 20 or 40 mg once daily for 4-8 weeks. If necessary, your doctor can adjust the dose.

Children aged 1-11 and weighing at least 20 kilograms should be given 10 or 20 milligrams once daily for 8 weeks. If necessary, your doctor can change the dose.

Children aged 1-11 and weighing less than 20 kgs should be given 10 milligrams once daily for 8 weeks. If necessary, your doctor can change the dose.

Children younger than 1 and weighing over 7.5-12 kgs should be given 10 milligrams once daily for around 6 weeks. If necessary, your doctor can alter the dose.

Children younger than 1 and weighing over 5-7.5 kgs should be given 5 milligrams once daily for around 6 weeks. If necessary, your doctor can alter the dose.

Children younger than 1 and weighing over 3-5 kgs should be given 2.5 milligrams once per day for around 6 weeks. If necessary, your doctor can alter the dose.

The use and dose of Esomeprazole Strontium in infants younger than 1 month must be decided by your doctor.

To treat GERD (gastroesophageal reflux disease):

Adults should take 20 mg once daily for 4 weeks. If necessary, your doctor may alter your dose.

Children aged 12-17 should take 20 mg once daily for 4 weeks. If necessary, your doctor can adjust the dose.

Children aged 1-11 should be given 10 mg once daily for around 8 weeks. If necessary, your doctor may need to adjust the dose.

Your doctor must decide the dose and use of Esomeprazole Strontium in children less than a year old.

To relieve Zollinger-Ellison syndrome:

Adults should take 40 mg twice a day. If necessary, your doctor can adjust your dose.

Your doctor is the one to decide the use and dose of Esomeprazole Strontium in children.

For oral form of dosage (24-hour delayed-release capsules):

To treat heartburn:

Adults should take 20 mg once daily for 14 days.

Your doctor is the one to determine the dose and use of Esomeprazole Strontium in children.

Interactions

When you're using Esomeprazole Strontium, it's really important to inform your healthcare provider if you're using any of the medications below. The following drug interactions have been picked based on their potential impact and aren't necessarily all-inclusive.

Using Esomeprazole Strontium with any of the medicines below isn't recommended. Your healthcare professional may opt to not treat you with Esomeprazole Strontium or alter some of the medications you use.

  • Rilpivirine

Using Esomeprazole Strontium with any of the medicines below is usually not advisable, but may be necessary in some situations. If your healthcare provider has prescribed both medications together, he or she may change how often you take both or one of them or change your dose.

  • Vismodegib
  • Neratinib
  • Capecitabine
  • Acalabrutinib
  • Escitalopram
  • Atazanavir
  • Cilostazol
  • Acalabrutinib
  • Citalopram
  • Bosutinib
  • Ketoconazole
  • Dasatinib
  • Methotrexate
  • Posaconazole
  • Gefitinib
  • Erlotinib
  • Eslicarbazepine Acetate
  • Clopidogrel
  • Saquinavir
  • Thiopental
  • Secretin Human
  • Ledipasvir
  • Tacrolimus
  • Mycophenolate Mofetil
  • Nilotinib
  • Nelfinavir
  • Sunitinib
  • Velpatasvir
  • Pazopanib

Using Esomeprazole Strontium with any of the medicines below may raise the risk of some side effects, but taking both medicines could be your best bet for treatment. If your healthcare provider has prescribed both medicines together, he or she may alter your dose or how frequently you use both or one of the medicines.

Warfarin

Risedronate

Voriconazole

Levothyroxine

Other interactions' certain drugs should not be taken with food or around meal times or when eating some kinds of food because interactions can occur. Using tobacco or alcohol with some medicines may make interactions occur as well.

Using Esomeprazole Strontium with any of these may raise the risk of some side effects but in some cases it may be unavoidable. If taken together, your healthcare provider may alter your dose or how frequently you use Esomeprazole Strontium, or issue you with special directions about using food, tobacco, or alcohol.

  • Cranberry

Warnings

It's vitally important that your healthcare professional monitors your progress on a regular basis. This will help your doctor determine if Esomeprazole Strontium is working well and to determine whether you should continue to use it. You may need urine and blood tests to check for adverse effects. Check with your healthcare professional if your condition becomes worse, or it doesn't improve.

Esomeprazole Strontium is sometimes taken together with antibiotics like clarithromycin and amoxicillin to treat ulcers. Make sure to understand about the proper use of other medications your healthcare professional prescribes with Esomeprazole Strontium, as well as the risks involved.

Check with your healthcare giver straight away if you develop a fever, skin rash, joint pain, unusual weight gain, or swelling of the ankles, feet, or body after taking Esomeprazole Strontium. These might be signs of severe interstitial nephritis.

Taking Esomeprazole Strontium for a prolonged period may make it more difficult for the body to take in vitamin B12. If you've got worries about deficiency of vitamin B12, tell your doctor immediately.

See your healthcare professional promptly if you pass watery stools that don't go away, or if you develop fever and stomach pain while taking Esomeprazole Strontium.

Esomeprazole Strontium may raise your risk of getting fractures of the spine, hip, and wrist. This is very likely to happen if you take Esomeprazole Strontium for at least one year or take high doses of the medication.

Systemic or cutaneous lupus erythematosus may happen or worsen in patients getting a proton pump inhibitor. Call up your healthcare provider if you've got a skin rash on the arms or cheeks that worsens when exposed to sunlight, or if you have joint pain.

Esomeprazole Strontium may lead to low levels of magnesium in your blood (hypomagnesemia). This is very likely to happen if you're taking Esomeprazole Strontium for longer than a year, or if you're using it together with certain water pills (diuretics) or digoxin (Lanoxin). See your doctor as promptly as possible if you develop seizures (convulsions), racing, fast, or irregular heartbeat, tremors, muscle spasms (tetany), or unusual weakness or tiredness.

Make sure any dentist or doctor that treats you knows you're using Esomeprazole Strontium. This drug can impact the results of some medical tests.

Don't take other drugs unless you've discussed it with your physician. This includes prescription drugs like atazanavir, nelfinavir, clopidogrel, reyataz, plavix, viracept, or over-the-counter (nonprescription) medicines, vitamin supplements, or herbal medicines (like St John's Wort).

Storage

Store Esomeprazole Strontium in a sealed container away from direct light, heat, and moisture.

Store Esomeprazole Strontium at room temperature.

Keep Esomeprazole Strontium from freezing.

Keep Esomeprazole Strontium out of children's reach.

Don't keep outdated Esomeprazole Strontium or one you no longer need.

Ask your healthcare specialist how you should get rid of any drug you don't use.

Summary

Don't alter your dose, stop using Esomeprazole Strontium, or use Esomeprazole Strontium beyond the recommended duration without consulting your doctor first.

Contact your healthcare provider if you've got any signs/symptoms of bleeding ulcers, such as tarry, black feces, or vomit that resembles coffee grounds. Also call your physician if you suffer chest pain, throat pain, trouble swallowing, or severe stomach pain.

Esomeprazole Strontium may result in dizziness or drowsiness. These effects can worsen if you use the medicine with certain medicines or alcohol. Use Esomeprazole Strontium carefully. Don't drive or carry out other potentially hazardous duties until you understand how you respond to Esomeprazole Strontium.

Esomeprazole Strontium may raise the risk of spine, hip, and wrist fractures in people with osteoporosis (weak bones). The risks could be bigger if you take Esomeprazole Strontium for longer than one year or in high doses or if you're older than 50. If you've got questions about this detail, be sure to contact your doctor.

Esomeprazole Strontium may raise the risk of some serious kind of diarrhea. Call up your physician immediately if stomach cramps or pain, persistent or severe diarrhea, or watery or bloody stools occur. Please discuss any concerns or questions with your physician.

Esomeprazole Strontium may impact certain laboratory tests. Make sure to tell the lab personnel and your physician that you're using Esomeprazole Strontium.

Observe caution when giving Esomeprazole Strontium to the elderly as they can be more vulnerable to its effects, particularly spine, hip, and wrist fractures.

Caution is recommended when giving children Esomeprazole Strontium. This is because they could be more likely to suffer drowsiness from using this medication.

You should observe extreme caution when giving Esomeprazole Strontium to children less than a month old. The safety and efficacy of the drug in these children haven't been established.

If you get pregnant, call up your physician. You and your doctor will need to talk about the risks and benefits of taking Esomeprazole Strontium while you're expecting.

It's unclear whether Esomeprazole Strontium gets into human milk. However, don't breastfeed while using the medication.

For more information about Esomeprazole Strontium, consult your healthcare specialist.