Fesoterodine (Oral)

Fesoterodine is used in patients who suffer from an overactive bladder to provide relief for the symptoms that the condition causes, including poor bladder control.

Overview

Fesoterodine is sold in the US under the brand name, Toviaz. The medicine is given on a doctor's prescription and comes in extended-release tablet format.

Fesoterodine is one of a class of drugs called antimuscarinics. It is used in the treatment of patients who have an overactive bladder. Overactive bladder typically causes uncontrollable contractions of the bladder's muscles, resulting in uncontrolled urination, a frequent urge to urinate and an urgent need to urinate.

The medication works by causing the muscles of the bladder to relax, thus effectively relieving the symptoms of the condition.

Fesoterodine cannot cure your overactive bladder problem, but it will do much to control it. You may have to use this drug for the rest of your life in order to maintain its effect.

Conditions treated

Type of medicine

  • Antimuscarinic
  • Extended-release tablet

Side effects

Some medicines may cause unwanted side effects, as well as the effects they are intended to have. Not everyone will experience any ill-effects while using fesoterodine, but if you do notice anything untoward, you should seek medical attention.

If you notice any of the following effects, you should check with your GP immediately:

  • Unexpected weight gain or loss
  • Unusual tiredness or weakness
  • Tingling in the feet or hands
  • Sore throat
  • Sneezing
  • Runny nose
  • Rapid weight gain
  • Nasal congestion
  • Pain in the lower back or side pain
  • Loss of voice
  • Headache
  • Frequent urge to urinate
  • Fever
  • Ear congestion
  • Dry mouth
  • Dry eyes
  • Difficulty in passing urine
  • Breathing difficulties
  • Constipation
  • Burning, difficult, or painful urination
  • Decrease in urine volume
  • Decrease in frequency of urination
  • Cough
  • Chills
  • Burning sensation while urinating
  • Body aches or pains
  • Bloody or cloudy urine
  • Swelling or bloating of the face, hands, arms, lower legs, or feet
  • Bladder pain

There are some side effects that are caused by fesoterodine that may go away on their own, without the need for further treatment. In addition, your treating physician may be able to suggest ways in which you can manage these effects. However, if the effects continue to be persistent after a week or so of using the new drug, you should check with your doctor:

The effects noted in this guide are not the only ones that have been reported by patients using this medication, although they are the most commonly experienced. If you suffer any other effects, mention them to your GP.

Dosage

You should only use this medication as directed by your GP. Do not take a higher or lower dose than you have been told to, do not take it more often than directed or for a longer period of time.

When you are issued your prescription, you should be given a medication guide. Read the information therein and make sure that you understand everything it contains. If you are unsure about anything, ask your treating physician for clarification.

Fesoterodine can be taken with or without a meal. It is important that you take the tablets whole. Do not crush, suck, split or chew them.

The dose of fesoterodine that you are prescribed will not necessarily be the same as for other patients. You must adhere to the directions given by your GP or follow the instructions on the label. The dose shown in this guide is purely based on the average. If you are told to take a different dose, you should not alter it unless you are expressly told to do so by your GP.

Your dose rate will depend on how strong the preparation is. In addition, the number of daily doses you are required to take, the time you should leave between each dose, and the total duration of your treatment will all be dependent on the health condition for which you are taking the drug.

For bladder control problems:

  • Adults: Initially, you should take 4 mg once daily. This dose may be increased if necessary. Under normal circumstances, you would not expect to take more than 8 mg once daily.
  • Children: The dose and use of this drug will be determined by your child's GP or specialist.

If you omit a dose of fesoterodine, leave out the dose that you missed and start again with your usual dosage regimen. Never take double the dose in an effort to make back the omission.

Interactions

There are some drugs that must never be used together. However, in some circumstances, it may be best for the patient's treatment program to use two of these drugs together, even though doing so could cause an interaction to take place. Before you begin using fesoterodine, you must tell your GP if you are currently using any other prescription or non-prescription drugs, including herbal remedies, vitamin supplements and diet pills.

It is not recommended that fesoterodine is used at the same time as any of the following medications. For this reason, your doctor may decide to use a different drug or may change some of the other medicines that you use:

  • Potassium
  • Itraconazole

It is not advisable to use fesoterodine with any of the drugs listed below. However, this may present the best course of action in your case. If both drugs are prescribed together, your GP may alter the dose or frequency of one or both of the medications:

  • Oxymorphone
  • Donepezil
  • Bupropion
  • Ketoconazole
  • Rifampin

Some drugs should not be taken at mealtimes or when eating particular food groups, as doing so could cause an interaction to take place. Similarly, some medicines interact with alcohol and tobacco. Before you begin using fesoterodine, you should discuss this aspect of your treatment with your GP.

Medical interactions

Some medical conditions can affect whether or not it is safe to use fesoterodine. You should discuss your medical history fully with your GP before you begin using fesoterodine.

Throughout the course of your treatment, you will be asked to attend your GP for regular checks to make sure that the drug is working as intended and to discuss any side effects that you may be experiencing. Be sure to attend these appointments.

Fesoterodine should only be used with extreme caution in patients with the following conditions, as to do so could make these conditions worse:

Fesoterodine should be used with extreme caution in patients who have kidney or liver disease. The effects of this drug may be increased, due to the slower removal of the drug from the patient's body.

Warnings

Before you decide to use a particular drug, you should weigh up the benefits and the risks it brings. To make the decision from an informed position, have a detailed discussion with your GP. In the case of fesoterodine, the considerations mentioned here should be borne in mind.

You should tell your GP if you have ever experienced any strange or allergic reactions to this medication or to any other medicines, including over the health products. You should also mention any allergies that you have to food preservatives, food colors, animal derivatives, or particular food groups.

Geriatric patients

Although there is no evidence to suggest that fesoterodine could cause any geriatric-specific issues, it can cause unwanted side effects in elderly patients. If you suffer any of the following effects, you should check with your doctor:

  • Constipation
  • Upset stomach
  • Dry mouth
  • Urinary tract infection
  • Age-related liver or kidney problems

Pregnancy and breastfeeding

There are no specific studies that have revealed any evidence to show that this drug may pose a threat to an unborn baby. However, if you are pregnant or considering becoming so while you are being treated with fesoterodine, you should discuss this with your GP before you take the medication.

There is nothing to suggest that fesoterodine passes into breast milk and thus to the nursing infant. However, you should weigh up the potential risks of doing so and consider changing to a different method of feeding your child while you are taking this drug.

Taking fesoterodine can cause some patients to produce less sweat. This can cause your body temperature to increase unexpectedly. Take care not be get too hot during warm weather or when you are taking exercise, as overheating could result in com/health/heat-stroke/">heat stroke.

You should not drink alcohol while you are taking fesoterodine.

Some patients who are taking fesoterodine may experience feelings of dizziness and drowsiness, and they may also suffer from blurred vision. If you are affected in this way, you must not drive or operate machinery. Do not undertake any other activities that could be dangerous if you are visually or physically impaired in this way.

Sometimes, fesoterodine can lead to mouth and nose dryness. In addition, your throat may feel dry and hoarse. You can relieve these annoying effects by chewing sugar-free gum, sucking candy or melting small pieces of ice in your mouth. Your doctor may also be able to provide you with a saliva substitute. However, if these problems persist for more than a couple of weeks, you should speak to your GP or dentist. If the mouth dryness continues, your chances of developing tooth decay, fungal infections and gum disease are increased.

While you are taking fesoterodine, you must not use any other medicines, including non-prescription products, vitamins or herbal remedies unless your doctor has given you the all-clear to do so.

Storage

You should store your supply of fesoterodine extended-release tablets out of direct sunlight and away from heat sources and moisture. Do not put the tablets in the fridge or freezer. Keep your prescription in its original container, sealed, and at room temperature.

Keep the medication well out of the reach of children and where pets cannot get hold of it. If a pet does eat any of your fesoterodine tablets, contact your vet for advice as a matter of urgency.

Do not keep or use out-of-date medicines. Do not use any tablets that have been damaged. Do not use fesoterodine tablets whose packaging has been opened or tampered with.

Any unused medicines should not be thrown down the toilet or drain. Place the tablets in a bag and seal it. Put the bag in the bottom of your trash can where it cannot be accessed by children or pets.

Summary

Fesoterodine belongs to a group of medicines called antimuscarinics. The medication is used to treat patients who are suffering from the symptoms of an overactive bladder. This condition typically causes contractions of the bladder's muscles, which result in a number of problems affecting the urinary system. Some people find that they have a continual feeling of needing to urinate. Others have little or no control over the bladder and 'leak' or dribble urine unexpectedly.

There are a number of side effects that this medication can cause in some patients. There are also some medical conditions that can cause an interaction with this drug. Be sure to discuss your medical history in detail with your treating physician before you agree to begin using fesoterodine.