Floxuridine (Injection)


There are a number of cancer treatments, but Floxuridine is one of the most popular in cases of colorectal cancer. It is given intravenously, usually as a shot or IV. This injection should be given under the supervision of a doctor, nurse or medically trained caregiver. This drug works by stopping the growth of new, rapidly developing cells. This targets cancer cells and stops them from spreading and forming.

This drug may have side effects, especially if you have just begun taking it. Some of these side effects may disappear or lessen over time, and some may require further attention. While unpleasant, enduring side effects are a necessary part of treatment. Your doctor may be able to give you tips and non-interactive medications to alleviate these side effects.

Floxuridine may cause low immunity. If you or a family member is being treated with this drug, do not needlessly expose them to infection or sick people. Vaccines should not be given to someone taking Floxuridine. Do not take Floxuridine if you have an allergy to this drug or any drugs of its kind. This drug should only be taken by those who explicitly need it, and reactions should be monitored closely. Notify your doctor if you are taking any potentially interactive medications or have a history of kidney/liver disease.

Be sure to speak with your doctor before beginning any treatment plan. Assess the risks and benefits, and make sure to ask questions about how this drug works, what it does and how it might affect you. Private research can be beneficial, but always direct questions to a trained medical professional.

Conditions Treated

Type Of Medication

  • Anti-metabolite
  • Chemotherapy drug

Side Effects

Side effects are common on this drug. Some may be mild, while others can affect your daily life. Not all of these side effects require medical attention or concern. Because of this drug's effects and strength, it can cause other issues within the body. These are natural and you may be able to prevent or lessen them with self-care and non-interactive medications.

Here is a list of common, harmless side effects:

  • Pain, swelling and peeling of the palms and soles of your hands and feet.
  • Hair loss
  • Loss of appetite
  • Nausea
  • Vomiting
  • Stomach upset
  • Mild diarrhea
  • Mouth sores

Some side effects may be a sign that something is wrong. If you experience anything troubling, strange or painful, talk to your doctor. While these are not immediately threatening, they are symptoms of a larger problem. Serious side effects include:

  • Severe diarrhea
  • Unrelieved and severe nausea
  • Severe vomiting
  • Blood in the urine or stools
  • Yellowing skin and eyes
  • Unusual bleeding and bruising

Allergies may occur during your treatment of this drug. While rare, some people may have a sensitivity to Floxuridine and are unable to take it. If you experience allergy symptoms, notify a doctor or nurse immediately. Allergic reactions can become fatal if left untreated and ignored. Do not take this drug if you have an allergy to Floxuridine or similar medications.

Allergy symptoms include:

  • Swelling of the face/tongue/hands
  • Closing of the airways
  • Tightness in the chest
  • Unexplained fever
  • Trouble breathing
  • Lightheadedness
  • Itching
  • Hives

If you experience a high fever after being administered this drug, contact medical help right away. Keep an eye on your reactions and side effects during your treatment with Floxuridine. This list is not exhaustive, so if you experience anything strange, you should tell your doctor.

If you have questions or concerns about how this drug may affect you, speak to your doctor before being given your first dose. While side effects are unpleasant, they may be a necessary part of receiving treatment. Your doctor is administering this drug for your benefit, so try to stay open-minded about the treatment.


The dosage of this drug should be decided only by your doctor. The amount of Floxuridine necessary can vary depending on your weight, age and the severity of your condition. Other factors may also change the dose necessary. If you have questions about how your doctor is determining your dose, be sure to ask them. Doses may change over time and your doctor should notify you if your dose changes.

This drug is given directly into an artery through an injection. It should be given by a nurse, medical caregiver or your doctor themselves. It is not recommended that you give this drug to yourself. You may be asked to schedule appointments to receive this drug at a hospital or cancer facility. Try to avoid missing appointments, reschedule them as soon as you're able.

Do not attempt to walk or drive yourself home after being given this drug. It is recommended that you schedule transportation for yourself. You can ask friends, family members or call taxis to take you home. If you are nervous about your treatment, you can ask friends or family to accompany you. Only take this drug if it is administered and recommended by your doctor.


Floxuridine may interact with other drugs you are taking. Be sure to list all of your medications while speaking to your doctor, and do not begin any new prescriptions without their approval. Drug interactions can vary between severe and mild, but you should avoid them if possible. Some drug interactions can cause this drug to work less effectively, while others may inhibit your body's ability to process this drug.

Keep a detailed list of your medications, and be sure to give it to your doctor before beginning treatment. This list should include herbal remedies, over-the-counter drugs and prescription medications. Your doctor may ask that you switch medications, lower dosages or stop taking certain drugs altogether. While unpleasant, this is necessary for your health.

If you are already being treated with other chemotherapy drugs, do not take Floxuridine. Doubling up on treatment will not help your condition, and it may cause serious illness. Only use Fluxoridine with your doctor's approval, do not risk your health any more than necessary. If you have bone marrow suppression, do not take this drug. If you have received radiation in your pelvic area, speak to your doctor before your first treatment.

This drug primarily interacts with vaccines and live infections. Do not expose yourself to any illness, and do not receive vaccines of any kind. This includes fairly benign vaccines such as the flu vaccine. If you are receiving this treatment during flu/cold season, take measures to avoid becoming ill.


This drug can pose risk to anyone and everyone who takes it. While some may be more at risk than others, you should discuss the risks and benefits of this drug before beginning your treatment. Your doctor should be able to give you a personalized outlook based on your previous medical history and condition.

This drug may cause immunodeficiency. Do not expose yourself to illness, avoid vaccines and sick people. If you are living with a person suffering from a transmittable illness, ask them to wear a face mask and avoid contact with you. Visitors should be asked to wear face masks as well, to avoid passing germs. You should wash your hands regularly and prepare your own food if possible.

If you are pregnant, have plans to conceive or become pregnant while using this drug, tell your doctor before your next treatment. Pregnancy is not recommended for this drug, as it can cause complications and the child can be harmed by the chemotherapy. Barrier methods of contraception are recommended to avoid accidental pregnancy. This drug may affect fertility, so discuss this aspect of the drug with your doctor if it concerns you.

If you've experienced issues with your kidney or liver, discuss this with your doctor. These conditions may make it difficult for you to process and rid yourself of this drug. Do not use this drug if you are currently suffering from an infection and do not use this drug if you are malnourished. A healthy diet and lifestyle are encouraged while using this drug.


Because this drug is given to you be a medical professional, you do not need to store or prepare it yourself. This drug is given intravenously, so the powder form must be mixed into a solution for injection. This process will be done by a trained nurse or doctor, so you should not have to learn the process. You should make a point to show up for your appointments on time, but preparing the drug is not your responsibility.

If you must be administered this drug at home, you should still require an at-home nurse or doctor visit. Likewise, the nurse will prepare this medicine for you. If you must store the drug within your home, the doctor will give you the manufacturer's information and storage requirements themselves.

Your doctor will be able to answer any questions about the storage and preparation of this drug.


Floxuridine can be a valuable resource for anyone suffering from cancer. By targeting cancer cells and preventing their growth and development, this drug can significantly affect the spread of colorectal cancer, stomach cancer and kidney cancer. This drug may also be used in the treatment of other cancers as well. If your doctor is recommending this drug, chances are they have chosen it based on your condition, experiences and reactions to other drugs.

This drug can cause hair loss and nausea, among other side effects. If these side effects become severe, talk to your doctor about possible solutions. Serious side effects should be monitored closely, you should contact your doctor if you experience fever or unusual bleeding and bruising. There are a number of potential side effects to this drug and every patient reacts differently. Talk to your doctor if you have questions or concerns.

Do not take this drug if you have an existing infection or an allergy to drugs of this kind. If you experience signs of infection or allergies, speak to your doctor right away. This drug should be administered at a health center by a trained nurse/doctor, so make sure to attend all of your appointments.