Framycetin (Ophthalmic)


Framycetin is one of the components of Neomycin, a powerful antibiotic that is used on many infections and in many preparations including ointments, creams and drops for the eye. Discovered in 1949, Neomycin is prepared as Framycetin especially for a solution that can be administered as drops to clear up eye infections. Framycetin is also available in an ointment formulation for the same purpose.

Framycetin is effective on bacterial infections only, with no activity against viral or fungus type infections. Specifically, Framycetin targets aerobic bacteria, such as those found in the conjunctivitis infection. Conjunctivitis is commonly called pink eye in the US and red eye elsewhere in the world. Framycetin is also effective against other infections of the eye caused by foreign materials, skin infections and can also be used to treat a stye,

Framycetin binds to the bacterium that causes the infection, fooling it into misreading the presence of a vital protein it needs to divide and grow. By stopping the growth of the infection and inhibiting the creation of new cells, Framycetin aids the body in killing off the bacteria sooner and ridding itself of the infection. Other drugs to soothe inflammation and pain may be prescribed at the same time.

Conditions Treated

Type Of Medicine

  • Antibiotic

Side Effects

Patients who have experienced hypersensitivity to Framycetin in the past or those who have reactions to other medications, animals, dyes, preservatives or other items may be at risk for a reaction to this medication as well. Be sure to inform your doctor of any allergies you've had to date.

You will be provided with a patient information hand-out that you should review prior to your procedure, asking any questions of your doctor or nurse prior to your surgery to make sure you understand the process and the use of Framycetin.


Your prescription will be written especially for you by your doctor and should be followed completely as written. Do not lengthen your treatment time, increase your dosage amount or change the frequency you have been prescribed to take Framycetin.

What your prescription reflects is the strength of the drug you are given, the health condition you are having and other considerations that pertain to you. If you have any questions about what you have been prescribed, check with your physician or your pharmacist.

Eye ointment

Adults will be instructed to apply Framycetin ointment format two or three times each day. Occasionally doctors will prescribe drops for daytime use and ointment for bedtime; in this case, only one treatment of ointment formulation will be required each day. Children will have their dosage amount written specifically for them by their physician.

To effectively and safely apply the ointment formulation of Framycetin, patients will be instructed as follows:

  • Wash hands
  • Tilt back your head
  • Press gently with index finger on lower eyelid creating a pocket
  • Squeeze ointment into this space in a line of 1 cm
  • Release eyelid and close eyes for at least two minutes
  • Avoid blinking
  • Do not touch ointment application tip to eye or skin
  • Wipe end with clean tissue and close tightly until next application

Eye drop solution

Adults will be prescribed one or two drops every few hours for the first two to three days, decreasing the dosage to three or four times per day after that. Children will have their dosage amount written for them by their doctor if deemed appropriate.

To effectively and safely apply the liquid drops formulation of Framycetin, patients will be instructed as follows:

  • Wash hands
  • Tilt back your head
  • Press gently with index finger on lower eyelid creating a pocket
  • Release one to two drops of medicine into pocket
  • Release eyelid and close eyes for at least two minutes
  • Avoid blinking
  • Do not touch dropper tip to eye or skin
  • Wipe end with clean tissue and close tightly until next application

Even if your infection begins to clear up and start to feel better, continue with your prescribed course of treatment of this medication to make sure all bacteria has been eradicated. Stopping your treatment early could cause bacteria to re-grow and flare up.

Missing your dosage of Framycetin isn't cause for alarm; if you are close to your next dosage time, skip the missing dose and continue on your schedule as before. If you remember far enough from your next dosage, however, take the missing dose.


Inform your physician if you have ever experienced sensitivity to antibiotic drugs such as Framycetin. You will also need to remember to disclose any sensitive reactions you've had to foods, animals, preservatives, dyes or perfumes prior to being treated with Framycetin.

Adult patients are the only age group that has been studied to determine if the active ingredients in Framycetin are effective and safe. No data has been provided on pediatric patients, and therefore the use of this medication on children is up to the individual physician and health requirement.

Geriatric patients are not expected to experience any age-related issues with safety or effectiveness with regard to use of this drug, but as there is no data available on this age group in that regard, use is up to the individual physician at the time of requirement.

Not all medications are safe to use together, but Framycetin will perhaps be prescribed with pain relief medications or anti-inflammatory drugs depending on the patient's need. For your own safety, do not take other medications while you are being treated with Framycetin unless they are specifically approved by your physician. Inform your physician of other drugs that you are taking including those sold over the counter, vitamin and herbal supplements as well as holistic remedies.


Patients known to be hypersensitive to other antibiotics such as neomycin and kanamycin may also be adverse to Framycetin use. High doses of this medication in patients who are intolerant to antibiotics or in children could cause adverse effects on health that are irreversible in nature. Dosage amount should be prescribed cautiously.

Women who are pregnant or those that may become pregnant should be made aware of the risks that use of this medication can pose to their unborn babies. Use of this medication on women who are pregnant is at the discretion of the physician and patient.

Women who are breastfeeding should also consider the possible risk of passing trace amounts of this medication on to their infants prior to allowing treatment with this medication. If possible, discontinue breastfeeding during your treatment with Framycetin and for a short period of time after the course of treatment runs out.

Use of Framycetin in your eyes may cause your vision to be blurred for a short time after. It is advised that you wait for your vision to clear before driving or operating power tools or machinery. If your vision is blurred for an extended period of time after application, contact your physician.


Keep your prescribed amount of Framycetin in the original packaging at room temperature, well away from light, moisture or heat exposure. Framycetin, as with all other drugs, should be kept out of sight and reach of children and pets.

If you have expired Framycetin or unused doses of this medication, consult with your doctor or pharmacist on the safest way to dispose of this drug. Never share this medication with other people even if they have the same condition as you.


Framycetin is an antibiotic treatment designed to target specific bacteria found in infections of the eye. Available in liquid drops or ointment applications, Framycetin is typically prescribed for conjunctivitis, also known as pink eye or red eye. By blocking the bacteria cell's ability to use proteins found in the body to divide and multiply, Framycetin effectively stops the bacterial growth and enables the body to rid itself of the infection.

The scientific study for effectiveness and safety of this medication was only performed on adult patients; therefore it is unknown if Framycetin is safe or effective to use on children. Geriatric patients, while not studied for effective or safe use of this medication either, can typically be prescribed dosages similar to those written for adults without issue. Women who are pregnant or breastfeeding are urged to consider all risks and alternative options for treatment other than Framycetin, if possible.

Adverse effects on health are few and typically related to hypersensitivity to antibiotic medications such as itching or redness. If you experience any health changes after receiving a treatment of Framycetin, report these to your physician immediately. Avoid taking other medications while being treated with Framycetin unless specifically prescribed to you by your physician. Patients with blurred vision after application are urged to wait until it clears prior to operating a motor vehicle or machinery.