Furazolidone is an artificial antimicrobial nitrofuran. It appears to be yellow, but its structure is stable and crystalline. Its inactive ingredients include FD & C Blue #2, calcium pyrophosphate, starch, magnesium stearate, and sucrose. Its liquid form contains sodium, carboxyl methylcellulose, flavors, magnesium aluminum silicate, glycerin, methylparaben, purified water, propylparaben, and sodium saccharin. Furazolidone is only sold with a qualified doctor's prescription. Over the counter, you may find Furazolidone in different forms available under the brand name Furoxone. Its dosage is mostly available in suspension or tablet forms. Furazolidone is taken by mouth, which allows it to work inside the alimentary canal to treat several intestinal diseases such as cholera, diarrhea and colitis, which are caused by bacteria as well as giardiasis.
It is the nature of any given medicine to bring some undesired effects in addition to the intended ones. Some of them may not occur but if they do, you might need to visit your doctor. The most common side effects associated with Furazolidone include:
Furazolidone is also known to change the color of urine to yellow or brown. This side effect does not require medical attention.
Some of the uncommon side effects are:
Some of these side effects may disappear during treatment because the body usually adjusts to accommodate the medicine. For the ones that persist, your medical doctor will be able to direct you on how to prevent or otherwise reduce them on your body. If after that you still find some side effects to be troublesome, report to your doctor immediately.
There may be some other side effects not listed in the above text. However, if you notice any other unusual feeling and you suspect that it may be caused by this medication, please check with your health professional.
The doses administered to various patients will differ from one patient to another. Therefore, one is required to strictly follow the doctor's prescription or the dosage indicated on the label. The difference in prescription is mostly because of the variance in the strength of the medicine. Additionally, the number of doses to take each day, the duration between doses and the amount of time you take the medicine all depend on the condition you have been diagnosed with, other medical conditions you may have, other medications you are taking, your weight, your height and your age or gender.
If your dose is unique, do not change it under any circumstance. The information we have provided below only includes the average doses that are supposed to be taken.
Use the provided, specifically calibrated measuring spoon or any other device that will measure the doses accurately. One is advised against using the average household teaspoon because it may not hold the recommended amount of medicine.
For oral dosage tablets or suspension for treating cholera or diarrhea that has been caused by bacteria:
I. Children who have reached the age of one month or above - The doses are based on the child's body weight. The weight must be determined by a doctor before the dose is given. The normal dose is 1.25 mg per kg or 0.56 mg per pound of the body weight. This is taken four times in a day for about a week.
Ii. Adults - 100 milligrams (mg) taken four times a day for about 5-7 days.
For treating giardiasis
I. For children who are one month of age and above - as earlier mentioned, the dose is given according to the weight of the body. The usual doses are 1.25 mg â€“ 2 mg per kg or 0.56 mg â€“ 0.90 mg per pound of the body weight. The medication should be taken four times a day for a week.
Ii. Adults should take 100 mg, four times a day for 7 â€“ 10 days.
Furazolidone should not be given to infants who have not reached 1 month of age unless advised otherwise by a qualified doctor or pharmacist. The medicine might cause anemia in these patients.
For any patient, Furazolidone may be taken in combination with food so as to diminish the chance of getting an upset stomach.
Even if the patient starts feeling better while taking the prescribed dosage, they should continue taking Furazolidone for the whole duration of treatment. This will help to treat the infection completely because the symptoms may sometimes return if you stop taking the medicine too soon.
If you miss a dose of this medication, you are advised to take it as soon as possible. However, if the time you want to take the missed dosage is too close to your next dose, it is advisable to skip the missed dose. Return to your regular dosing schedule and make sure you do not double dose.
Furoxone tablets, 100 mg each, are sold in amber bottles that contain 20 and 100 tablets. The liquid medicine is supplied in amber bottles that contain 60 ml and 473 ml.
Usually, certain medicines should not be taken together at all. However, in some conditions, the doctor may recommend two medicines to be used together even if an interaction may occur. In such cases, the doses of the medicines should be changed in a way that your body can handle them. If Furazolidone has been prescribed for you, make sure that your doctor is aware of any other medication that you take.
Here is a list of some medications whose use is not recommended in combination with Furazolidone: Amitriptyline, Amphetamine, Apraclonidine, Atomoxetine, Benzphetamine, Brimonidine, Bupropion, Carbamazepine, Carbidopa, Carbinoxamine, Citalopram, Clomipramine, Clovoxamine, Codeine, Cyclobenzaprine, Cyproheptadine, Desipramine, Desvenlafaxine, Deutetrabenzane, Dexmethylephenidate, Dextroamphetamine, Diethylpropion, Doxylamine, Entacapone, Escitalopram, Femoxetine, Flouxetine, Fluvoxamine, Guanadrel, Guanethidine, Hydroxytryptophan, Imipramine, Isocarboxazid, Levodopa, Levomethadyl, Levomilnacipran, Lisdexamfetamine, Maprotiline, Mazindol, Meperidine, Methamphenidate, Milnacipran, Mirtazapine, Nefazodone, Nefopam, Nortriptyline, Opicapone, Opipramol, Paroxetine, Phendimetrazine, Phentermine, Phenylalaline, Reserpine, Safinamide, Selegiline, Sertraline, Sibutramine, Sumatripan, Tapentadol, Tetrabenazine, Tramadol, Tranylcypromine, Trazodone,Trimipramine, Tryptophan, Venlafaxine, Vilazodon, Vortioxetine, and Zimeldine.
If Furazolidone is used with the medicines below, the doses should be changed. The medicines include: Alfentanil, Altretamine, Buprenorphine, Butorphanol, Cholera Vaccine, Difenoxin, Dihydrocodeine, Diphenoxylate, Dolasetron, Droperidol, Ephedrine, Ethchlorvynol, Fentanyl, Frovatriptan, Granisetron, Guarana, Hydrocodone, Hydromorphone, Iobenguane, Kava, Levophanol, Liciricw, Lorcaserin, Ma Huang, Mate, Metraminol, Methadone, Methylene Blue, Midodrine, Morphine, Morphine Sulfate Liposome, Naratriptan, Norepinephrine, Oxycodone, Oxymetazoline, Oxymorphone, Palonosetron, Pentazocine, Phenylephrine, Phenylpropanolamine, Reboxetine, Remifentaln, St. John's Wort, Sufentanil, Tyrosine, Valbenazine, and Ziprasidone.
When Furazolidone is used with any of the following medicines, it may increase the risk of getting certain side effects. The doctor may be aware of this but will still prescribe the medicines so that they can achieve the best results. The medicines are: Acarbose, Chlorpropamide, Ginseng, Glimepiride, Glipizide, Glyburide, Insulin, Insulin Aspart, Insulin Bovine, Insulin Degludec, Insulin Detemir, Insulin Glargine, Insulin Glulisine, Insulin Lispro, Metformin, Nateglinide, Repaglinide, Tolazamide, and Tolbutamide.
The interactions named above have been selected based on their potential significance but are not necessarily all-inclusive.
Due to the possibility of some interactions occurring, there are some medicines that should not be taken at or around the time of eating food or eating some specific types of food. The foods indicated below are selected according to their effects but are not limited to:
Using alcohol or tobacco with certain medicines may cause interactions to occur. Using Furazolidone with these and the above-mentioned substances is not recommended. The doctor should decide whether or not to treat you with Furazolidone if the use of these foods, alcohol or tobacco is unavoidable.
There may be instances of interactions with Furazolidone for specific patients who suffer certain health conditions. One should make sure that they inform their doctor especially if they are suffering from Glucose-6-phosphate dehydrogenase deficiency. This is a condition caused by the lack of G6PD enzyme. The patients who have this condition may develop anemia if they take Furazolidone.
When deciding to use Furazolidone medicine, there are a number of risks that must be weighed against the benefits of using it. This decision should be between you and your doctor based on the various precautions that should be observed when taking Furazolidone. Some of the most common precautions include:
The drug should be stored in a closed container and at room temperature. Additionally, Furazolidone should be kept away from heat, direct sunlight and moisture. The medicine should not be frozen.
Ensure that you store Furazolidone away from children.
One should not keep expired medicine or medicine that is no longer being used. Always read the sticker on how to dispose the drug or ask for expert assistance.
From the details above, it is clear that the use of Furazolidone has so many advantages. It is very effective in healing infections that have been caused by either bacteria or protozoa. The antibiotic is especially useful in taking out any bacteria around the alimentary canal when taken by mouth. However, even with its numerous benefits to our bodies, Furazolidone should be taken with extreme caution and only with a qualified doctor's prescription. It should not be given to children under the age of one month. Specific groups of people such as pregnant women and hemophiliacs should consult qualified doctors before starting to take this medicine. Furazolidone is known to have reactions with many other drugs so one should seek an expert's opinion to know the combination of medicines to avoid.