Fusidic Acid (Injection, Oral)

Fusidic Acid is a treatment taken orally or by injection and used against staphylococcal (bacterial) infections.


Fusidic Acid is used to treat staphylococcal infections occurring because of bacteria. Commonly treated ailments include cutaneous infections, pneumonia, septicaemia, wound infections, endocarditis, osteomyelitis and superinfected cystic fibrosis.

This medication is usually given orally unless oral administration is inappropriate. This could occur because of stomach discomfort or because absorption from the gastro-intestinal tract is unpredictable.

Fusidic Acid will not be effective in the treatment of viral infections such as the flu or colds.

This medication is only available when prescribed by a doctor and is administered as Fucidin Suspension in a range of forms.

Condition treated

  • Bacterial infection

Type Of Medicine

  • Steroid antibiotic

Side Effects

In addition to the much needed effects of this medication, Fusidic Acid can also cause unwanted side effects to occur. While not all of these side effects may occur, patients may need to seek medical attention in cases where they do.

You should contact your doctor for immediate advice if you experience any of the following rare side effects from the use of Fusidic Acid:

  • Unusual tiredness
  • Unusual weakness
  • Yellowing of the eyes
  • Yellowing of the skin

Other side effects can also occur that would not normally require you to seek medical attention from the doctor. These treatments will usually abate over time as the body becomes used to the medication and would not normally be an indication of wider medical problems that may be occurring. If these side effects do become bothersome for you or are ongoing, however, then you should seek advice on how to alleviate them from your healthcare professional:

  • Abdominal pains
  • Increased frequency of bowel movements
  • Loosening of stools
  • Loss of appetite
  • Nausea
  • Sickness
  • Stomach pain

Other side effects can also occur that may not have been listed here. If you experience other side effects then you should seek advice from your doctor. If you are worried about your immediate health, however, then you should always contact the emergency services for emergency care.


The dose of this medication given will differ for different patients. You should only ever use this medication as you have been directed to by your doctor and following the instructions provided. You should not ever use it for the treatment of conditions other than those for which it was prescribed.

The amount of medication prescribed will vary depending on the strength of the medication, the period for which you will be taking it, the time between doses and your personal medical condition. You should take this medication only as prescribed. The following information is for the purpose of being a guideline only and should not be used to adjust your own treatment against doctor's orders:

When treating osteomyelitis or infections of soft tissue with tablets:

  • Adults should take 500mg of medication, which is usually 2 tablets, three times per day.

When treating osteomyelitis or infections of soft tissue with oral suspension:

  • Adults should be treated with 15ml taken 3 times per day.
  • Children aged 6-12 years should receive 10ml three times per day.
  • Children aged 15 years should receive 5ml three times per day.
  • Children aged up to 1 year should receive 1ml/kg per day. This dose should be calculated by the doctor and then divided into 3 doses to be given during the day.

When treating osteomyelitis or infections of the soft tissue with injection:

  • Adults should be given 500mg of medication three times per day.
  • Children aged up to 12 should be treated with 20mg/kg of body weight in total during the day. The doctor should calculate this dose and then divide it into 3 doses that should be infused over a period of at least 2 hours.

If a dose of this medication is missed then you should take it as soon as it is possible to do so. If you are close to your next dose being due, however, then you should skip the dose entirely and return to your normal dosing schedule. You should never take a double dose of this medication and should not try to make up' for a missed dose by increasing your dose.


Certain medications should not be used in conjunction with one another. This is because they can interact with each other in the body and this can cause severe medical problems in the patient. When medications react violently there can be life-threatening results. In other cases medications may prevent one another from working or may increase the risk of certain side effects occurring from one or both of the treatments. Before beginning treatment with any medication it is very important that you inform your doctor of any other treatments that you are taking so that you can avoid experiencing any unwanted interactions. This includes any herbal remedies, vitamin supplements, dietary supplements, over the counter treatments and prescribed medications that you are taking. For Fusidic Acid this is especially important in the following cases.

The use of Fusidic acid is not normally recommended in patients who are taking any of the following. When treatment with both medications is required the doses or frequency of use of each medication must be amended as appropriate to the situation:

  • Simvastatin
  • Saquinavir
  • Ritonavir
  • Pravastatin
  • Cholera Vaccine, Live
  • Atorvastatin

Other drug interactions can also occur that have not been listed here. Ensure that you have informed your doctor of all medications that you are taking before taking Fusidic Acid.

Certain medical conditions can also impact the use of certain treatments. Conditions not being treated with a medication may be worsened by use or may increase the side effects that are experienced from use of the medication. You should inform your doctor of your full medical history before beginning treatment. In the case of fusidic acid, the following condition may be significantly worsened by the use:


Before you begin use of any medication you must weigh the benefits of use against the potential risks of use. The decision to take any treatment should be made with your doctor and should take into account all of the following:

Allergies: If you have any allergies this may effect the use of Fusidic acid. Ensure your doctor is aware of all allergies to dyes, preservatives, medications, foods, animals or other substances before beginning treatment.

Breastfeeding: There have been no adequate studies carried out to determine the risk of breastfeeding during use of this treatment. You should weigh the potential risks of breastfeeding with the benefits and discuss this with your doctor.

You should check in with your doctor if you are not experiencing an improvement in your condition after a few days of treatment. This may mean that there is another condition that may need to be treated too.

You should not take any other medications at the same time or during the same period as taking Fusidic Acid unless expressly told to by your doctor. If you need other treatment for pain relief or other conditions then you should discuss the use of these with your doctor. You should not take any medications purchased over the counter intended for the treatment of coughs, colds, hay fever, sinus problems, aspirin or medications for sinus problems. All of these may interact with fusidic acid and may make conditions worse rather than better.


You should store this medication in a sealed container at normal room temperature. Ensure that it is kept out of direct light, away from moisture and away from heat. You should prevent Fusidic Acid from freezing.

Always keep all medications out of the reach of children.

Dispose of any outdated or unwanted medication safely as directed to by your doctor or healthcare professional.


Fusidic acid is used to treat certain bacterial infections in the patient. It is not effective against any viral conditions and should not be used in the treatment of colds, flu or other viruses.

This medication should be given orally where it is possible to do so and should only be given by injection in cases where there is a limitation to the use of oral treatment.

Treatment is effective in adults and in children. When treating children the oral suspension should be used in preference.

Fusidic acid should only be administered as an injection by a doctor or other trained healthcare professional. The oral tablet and suspension should only be used as prescribed and only used for the condition for which it was prescribed.

Patients should not use other medication in conjunction with Fusidic Acid unless approved by the prescribing doctor.