Hepatitis B Vaccine (Intramuscular)


Hepatitis B vaccination recombinant is a vaccine used in the prevention of hepatitis B virus. This vaccination works by causing your body to produce its own antibodies against the disease.

This vaccine is not made with blood products, human blood or other variants of human origin. It can't give you human immunodeficiency virus (HIV) or hepatitis B virus (HBV).

HBV is a large factor in causing serious liver disease, such as cirrhosis and hepatitis and primary hepatocellular carcinoma which is a form of liver disease.

Pregnant women who have hepatitis B infection or are carriers of the virus can pass the disease onto their babies when they are born. These infants often suffer from serious long-term infections and illnesses as a result.

Immunization against hepatitis B disease is recommended for all children, newborn babies, infants, and adolescents up to 19 years of age. It's also recommended for adults who live in areas that are known to be a high-risk area or who are at an increased risk of contracting the virus. These adults include:

  • People who suffer from blood clotting disorders who receive clotting factor concentrate transfusions.

You can only obtain this vaccination from your doctor or similar healthcare professional. This product is available in the dose form of a solution for suspension.

Conditions treated

  • Sexual Transmitted Disease Exposure from Sexual Assault

Type of medication

  • Solution for suspension

Side effects

Along with preventing the development of hepatitis B, this drug can produce some unwanted side effects. Not all of these side effects may occur at the one time, however, if they do occur, you may need to seek medical attention

Seek medical advice from your doctor or healthcare professional right away if you suffer from any of the following side effects whilst taking hepatitis b vaccination:

More common

  • A fever of over 100 degrees F (37.7 degrees C) or above


  • Sweating

Some side effects of hepatitis b vaccination that occur usually don't require medical attention as they aren't overly serious. You usually find that these side effects begin to disappear as your body begins adjusting to the medication. However, if you are finding the side effects are bothersome, you should contact your local healthcare professional or pharmacist for advice on ways to prevent or reduce the severity of these side effects.

Consult your doctor if any of the following side effects become bothersome or remain persistent.

More common

Less common

  • Unusual weakness or tiredness


  • Sudden redness of skin

You may experience other side effects that are not listed above. Contact your doctor if you notice anything unusual and remember you can report all side effects to the FDA.


The final dose of any medication will depend upon a variety of factors. This will include your weight, age and height, any other medication you are currently taking and any other medical conditions you may suffer from. You will not need to worry about dosing for this medication as you will receive it from a trained professional in a medical setting. This vaccination is given as an injection into one of the muscles in your arm. If you suffer from bleeding problems, however, it may be given as an injection under your skin.

This vaccination is typically given in three doses. After the first dose, two more doses are given one month and six months after the first dose, unless your doctor tells you differently.


This vaccination can interact with other medications you are taking. This could result in severe side effects or reduce the effectiveness of either drug in treatment. To help limit the risk of these interactions, it's important that you give your doctor or healthcare professional a full list of all the current and past medications you are taking. This should include over the counter drugs, prescription, and non-prescription drugs, vitamin supplements and herbal remedies. It's also a good idea to let your doctor know of any other medical conditions you currently suffer from.

Let your doctor know if you are currently taking any of the following drugs. Depending on the severity of potential interaction, your doctor may avoid treating you with the drug altogether or alter the dose or frequency in which you use either drug.

  • Anakinra

The presence of other medical conditions could increase your risk of certain side effects or interactions. It's therefore important that you let your doctor or healthcare professional know of any other medical conditions you suffer from including:

  • A weak immune system from a disease or medication this drug may not work as well.



You should inform your doctor or nurse if you have ever suffered an allergic reaction to this vaccine before, or similar vaccines. You should also make your doctor aware of any other allergies you may suffer from including animals, dyes, preservatives, and foods.

Pediatric population

Appropriate studies conducted to date have not indicated a pediatric-specific problem that could limit the effectiveness of hepatitis B vaccine recombinant in young children.

Geriatric population

Appropriate studies conducted to date have not indicated a geriatric-specific problem that could limit the usefulness of this vaccine in the elderly population.

Use in pregnancy and breastfeeding

This drug is under FDA pregnancy category C. This means it is unknown whether this vaccination can harm an unborn baby. You should let your doctor know if you are pregnant whilst receiving the series of vaccinations.

It is unknown whether hepatitis B vaccination can pass into breast milk or if it could potentially harm a nursing infant. Let your doctor know if you are currently breastfeeding a baby.

It's extremely important that you arrive at the correct time for your 2nd and 3rd dose of this vaccine. You should inform your doctor of any unwanted side effects after receiving this vaccination.

This vaccination can cause a serious type of allergic reaction known as anaphylaxis. This can be life-threatening and requires urgent medical attention. Inform your doctor immediately if you or your child suffer from itching, a rash, swelling of the throat and tongue or trouble breathing after you receive this vaccination.

Let your doctor know if you or your child has an allergy to latex. The rubber plunger and needle cover of the prefilled syringe contains natural dry latex rubber, which could cause allergies in those who suffer from this allergy.

This vaccination may not protect you against hepatitis B infection if you are already infected once you receive the first dose.


This medication will be stored in a clinical setting, so you will not need to worry about storage at home. This vaccine is typically refrigerated until use.


When used correctly, the hepatitis B vaccine is successful in preventing the development of hepatitis B. This vaccination is recommended for people of all ages, especially those who in the higher risk category (listed above) of contracting the disease. You should let your doctor know if you are pregnant or breastfeeding whilst receiving this medication. It's important you receive all three doses of this medication. Your doctor or healthcare professional will give you a vaccination schedule to follow. If you are suffering from an illness at the time the vaccine is scheduled, your doctor may delay the injection until you are feeling better. If you have any further questions about the practical uses of this vaccine or any queries, you should contact your local doctor or healthcare professional for advice.