Hydrocortisone and Acetic Acid (Otic)


Corticosteroid and acetic acid is a combination drug that is used in the treatment of specific problems of the ear canal. This drug can also help relieve the itching, redness, and swelling that can accompany these ear conditions.

These medications can also be used for other conditions that will be determined by your doctor.

You cannot obtain this medication on your own, it requires a prescription from your doctor. This product is available in the dosage form of a solution.

Conditions treated

  • Inflammation of the External Ear Resembling Seborrhea

Type of medication

  • Solution

Side effects

Alongside treating ear problems in the ear canal, this drug can also produce some unwanted side effects. These side effects may not all be present at once, but if they do occur you may be required to seek medical attention.

Some of the side effects that occur with acetic acid/hydrocortisone otic typically are not severe and won't require medical attention. You will find that these side effects generally begin to disappear or reduce as your body becomes adjusted to the medication. However, if you are finding them bothersome, you can contact your local pharmacist or doctor for advice on ways to prevent or reduce these side effects. You should contact your local healthcare professional or doctor if any of the following side effects become persistent or become bothersome.

Less common

  • Itching, stinging, burning in the ear or irritation

You may suffer from side effects that are not listed above. Contact your doctor if you notice anything unusual. Remember you can report all side effects to the FDA.


The amount of medication that you take will depend upon a variety of factors. These include your weight, age and height, any other current medications you are taking, any other medical conditions you suffer from and your reaction to the first dose. Addition factors will depend on the strength of the medicine, the number of doses you will receive each day, the duration you are on the medication and the specific condition you are being treated for.

It's extremely important that you do not alter any doses without consultation with your doctor. If you take too much of a medication, you could increase your risk of severe side effects and if you take too little, you could reduce the effectiveness of the treatment.

For ear drops dosage form for ear infections:

Adults and children aged three and above: Use three to five drops in the affected ear every 4-6 hours for the first 24 hours, then five drops 3-4 times daily.

Children age 3 and under'The dose and use will be determined by your doctor but use in those under 3 years old is not recommended.

Missed Dose

If you have missed a dose of this medication, you should apply it as soon as you remember. The exception to this is if it's also time for your next dose. If this is the case, you should skip the dose you missed and revert back to your original dosing schedule.

You should not stop treatment abruptly.


Drug interactions can cause severe side effects and reduce the effective nature of the drugs you are taking. To help minimize the risk of this happening, it's important that you give your doctor a complete list of all the current and past medications you are taking. This should include all prescription, nonprescription drugs, over the counter medications, vitamin supplements, and herbal products. It's also important to make your doctor aware of any other medical conditions you currently suffer from, as these too could increase your risk of interactions.

The use of this medication alongside any of the following medicines is not typically recommended. Your doctor may avoid treating you with this drug altogether or alter some of the other medications you take.

The use of this medication alongside any of the following medications is not usually recommended. However it some cases it may be necessary. If you are given both medications at once, your doctor may alter the dose or frequency in which you use either medication.

  • Valdecoxib

The use of this medication alongside any of the following drugs could increase your risk of certain side effects, however, in some cases, the use of both drugs may be the best option for treatment. If you are given both medications at the same time, your doctor may alter the dose or frequency in which you use either medication.

  • Levofloxacin

Other Medical Conditions

The presence of other medical conditions could potentially affect the proper use of this medication. You should let your doctor know if you suffer from any other medical conditions, including:

  • Punctured eardrum'The use of this drug could damage the ear.



It's important that you let your doctor or healthcare professional know if you have ever suffered from an unusual or allergic reaction to this medication before, or similar medications. You should also make them aware of any other allergies you suffer from, including, animals, dyes, preservatives, and foods.

Pediatric population

There is currently no specific information that compares the use of otic corticosteroids in children under three tears of age against the use in other age groups. Therefore safety and efficacy have not yet been established.

Geriatric population

Although there is currently no specific information that compares the use of otic corticosteroids in the older population alongside the use in other age groups, it's not expected to cause a variation in problems or side effects in the elderly than it does in younger adults.

Pregnancy and breastfeeding

This drug is under FDA pregnancy category C. This means it is unknown whether this drug could harm a baby. It is also unknown whether this drug can pass into breast milk and harm a breastfeeding baby. You should let your doctor know if you are pregnant or currently breastfeeding an infant.

Acetic acid and hydrocortisone are not for use in children younger than three years old.

Proper use

  • Tilt the head or lie down so that the affected part of the ear is facing upwards.

For those using hydrocortisone and acetic acid combination drops for the ear:

  • Don't wash the applicator tip or dropper as the water could seep into the medication and make it weak. If you need to, you can clean the applicator tip or drop with a clean tissue.

Don't use any leftover medication for future ear problems without first consulting with your healthcare professional or doctor. This medication cannot be used in other types of ear infections are present as it could make these conditions worse.


This medication needs to be stored in a closed container and kept at room temperature. It should also be kept away from moisture, heat and direct light. Prevent this medication from freezing. Remember to keep this medication out of the reach of children. Do not keep medication that has passed its expiry date or you no longer require. You should seek advice from your local pharmacist for the best way to dispose of medication you no longer require.


When used correctly, Hydrocortisone and Acetic Acid are successful in the treatment of ear canal infections. Due to a large number of interactions possible with the use of this drug, it is important that you give your doctor or healthcare professional a full and complete list of all the current medication you are taking. You should let your doctor know if you are currently pregnant or breastfeeding. This drug should not be used in children under the age of three years old. Safety and efficacy have not been established in children. If your condition does not begin to improve within five to seven days, or if it becomes worse, you should seek advice from your doctor. Ensure that you used this medication regularly in order to receive the full benefit from it. You should use it at the same time each day and a diary or alarm can help you keep on schedule. Continue to use it for the full time that has been prescribed by your doctor even if your symptoms begin to disappear after a couple of days. If you stop this medication too early, you can allow bacteria to grow and the infection to return. If you require any further information on the practical uses of this drug combination or have any other questions, you should contact your local doctor or healthcare professional.