Hypromellose (Intraocular)


When eye surgeries are carried out, it's vital that surgeons maintain the shape of the eye. When the nature of the surgery puts the shape of the eye at risk, such as lens implantation procedures or cataract surgery, Hypromellose is used as a surgical aid.

In addition to this, the tissue surrounding the eye must be protected from any potential damage while surgery is being carried out. By using Hypromellose, surgeons can ensure that surgical tools do not harm the surrounding tissue and, as a result, the risk of complications arising from the operation is reduced.

Due to its viscoelastic properties, Hypromellose is effective in both maintaining the eye and protecting the surrounding tissues while surgical procedures are carried out. When used during specific operations, Hypromellose can increase the chance of the surgery being successful and reduce the risk of the patient suffering side effects following the procedure.

Conditions Treated

  • Used as a surgical aid

Type Of Medicine

  • Viscoelastic polymer
  • Ocular lubricant

Side Effects

As with most medications, patients can experience some side effects when Hypromellose is used during a surgical procedure. If patients notice the following side effects after eye surgery, they should inform their physician straight away:

  • Blurred vision
  • Pain in the eye
  • Change in vision
  • Headache
  • Decreased vision
  • Sensitivity of the eye to light
  • Loss of vision
  • Tearing of the eye
  • Redness inside the eyelid or of the white part of the eyes
  • Nausea
  • Throbbing eye pain
  • Pooling of a whitish fluid visible on the colored part of the eye

Patients should also notify their doctor if they experience any other side effects after being treated with Hypromellose during surgery. In addition to this, patients can notify the Food and Drug Administration if they experience any side effects that are not listed above. This helps the FDA to collate accurate data regarding the adverse effects associated with Hypromellose. If patients wish to notify the FDA of any additional side effects, they can contact them on 1-800-FDA-1088.


When prescribed as a surgical aid, Hypromellose is normally used at a strength of 2%. As physicians will administer this medication during surgery, they will determine what dose is appropriate as the procedure is taking place. If the surgery takes longer than expected, the patient's dose of Hypromellose may be increased accordingly.

Although Hypromellose can be prescribed in other forms for home use, when Hypromellose is used as a surgical aid, it will only be administered by a qualified healthcare professional. Due to this, patients will not have to calculate their dose of Hypromellose or administer the medication themselves.

Potential Drug Interactions

When patients use or take more than one medication, there is a risk that the active ingredients could interact. Although not every interaction is dangerous, some are more harmful than others. Due to this, patients should inform their doctor if they are using any other medicines before undergoing surgery involving Hypromellose. Once the patient's physician has this information, they can determine whether the patient can be treated safely with Hypromellose during surgery.

In addition to this, patients should seek advice before using prescription medication, over the counter medicines, supplements or vitamins after undergoing surgery involving Hypromellose.


If patients have any existing health problems, it may affect the safe use of Hypromellose during an operation. Similarly, the patient's medical history or past conditions could affect the use of Hypromellose. Due to this, patients will need to disclose their medical history and current diagnoses to their physician before they are treated with Hypromellose. The following conditions, in particular, are relevant to treatment using Hypromellose:

If patients have a history of glaucoma, using Hypromellose could worsen their condition. Due to this, physicians may decide not to use Hypromellose during the patient's surgery.

Similarly, if the patient has diabetes, they may experience increased side effects if Hypromellose is used. While this won't necessarily prevent physicians from using Hypromellose during the patient's surgery, they may use a modified dose of the medication in order to reduce the risk of side effects occurring. Alternatively, they may provide the patient with additional medication following surgery in a bid to reduce the side effects they may experience.

After undergoing surgery with Hypromellose, patients will need to consult with their physician. Normally, patients will be required to see their physician for follow-up appointments in the weeks following their surgical procedure. This will enable their doctor to assess their progress and confirm that Hypromellose has not had any unwanted effects.

On occasion, patients may experience serious eye problems following treatment with intraocular Hypromellose. If patients notice any of the following symptoms after being treated with this medicine, they should seek medical help straight away:

  • Change in vision after surgery
  • Red eyes
  • Nausea
  • Headaches
  • Painful eyes
  • Increased sensitivity to light
  • Excessive eye tearing

If patients are pregnant, they may not be treated with Hypromellose. Currently, the Food and Drug Administration has ruled that Hypromellose is considered to be a category C drug when viewed in relation to pregnant patients. This means that treatment with Hypromellose may cause harm to an unborn fetus. Due to this, patients who are pregnant should not be treated with Hypromellose unless the benefits greatly outweigh the risks. If pregnant patients are treated with Hypromellose, their physician should explain the potential risk to the fetus before the medication is used.

If patients are pregnant and are due to undergo surgery involving Hypromellose, they must notify their physician beforehand. As well as Hypromellose posing a potential risk to the unborn baby, the surgery itself may present a risk to the patient or the unborn fetus.

When patients take or use medications and breastfeed, the medication may be transferred to the infant. To date, there have not been relevant studies assessing whether Hypromellose can be transferred to an infant via breastfeeding or whether this would pose significant risk to the child. Due to this, patients who have been treated with Hypromellose during surgery are usually advised not to breastfeed.

Furthermore, if patients are treated with intraocular Hypromellose, they should obtain medical advice before they resume breastfeeding. In some cases, medication can remain in the patient's system for some time and could potentially pose a risk to an infant if the patient were to resume breastfeeding soon after being treated with Hypromellose.

Before undergoing surgery with intraocular Hypromellose, patients should inform their doctor if they have any known allergies or if they have ever experienced an allergic reaction. This includes allergies to medicines, foods, preservatives, dyes or animals. In rare cases, patients may experience an allergic reaction after Hypromellose has been used during surgery.

A serious allergic reaction can be life-threatening, so it's essential that the patient receives emergency medical attention if they begin to display symptoms of an allergy. These symptoms may include:

  • Wheezing
  • Shortness of breath
  • Difficulty swallowing
  • Difficulty breathing
  • Hoarseness
  • Rash on the skin
  • Itching
  • Hives
  • Swelling of the face, lips, mouth, tongue, throat or hands


When storing Hypromellose, the manufacturer's specific instructions should be followed. These will ensure that the medication is kept in good condition and is ready for use.

In order to protect the medication, intraocular Hypromellose should typically be stored between temperatures of 15?-30?C (59?-86?F). However, intraocular Hypromellose should be well-maintained if it is kept below a temperature of 40?C (104?F).

Stored in single-use glass syringes, intraocular Hypromellose needs to be protected from the light prior to use. Once open, the syringe and any excess Hypromellose should be disposed of safely.

As intraocular Hypromellose is administered in a clinical setting by a professional healthcare practitioner, patients will not be required to store this type of medication themselves.


When intraocular Hypromellose is administered during eye surgery, it enables physicians to carry out the operation more safely and with a greater degree of success. By providing additional protection to the corneal endothelium and the surrounding tissues, there is less likelihood of complications arising from the surgery.

Due to its viscoelastic nature, intraocular Hypromellose will fill space within the eye chamber and allow the surgeon to manipulate the tissue more easily. In addition to this, the use of intraocular Hypromellose ensures that surgeons can maintain a deep chamber during surgery, potentially increasing the efficacy of the procedure.

As well as using intraocular Hypromellose to fill the anterior chamber during surgery, physicians may use Hypromellose to coat their surgical instruments prior to use. This also helps to reduce the risk of trauma to the surrounding tissues and ensures that the surgeon is able to conduct the procedure with increased accuracy.

Intraocular Hypromellose can cause serious side effects on rare occasions and the majority of patients do experience side effects as a result of Hypromellose being used as a surgical aid. As the eye is irrigated to remove the intraocular Hypromellose at the end of surgery, patients do not normally suffer any negative consequences as a result of this medicine being used during surgical procedures.