Indapamide (Oral)


Indapamide is a drug given to patients who are suffering from hypertension (high blood pressure). As a diuretic, Indapamide is able to increase the body's flow of urine, and your subsequent build-up of water.

It is important that you treat hypertension as soon as possible, as it can lead to some very serious health conditions, such as strokes, kidney failure, or heart failure. These problems come about when your arteries and heart are no longer able to function properly. This is because the high blood pressure you are suffering from adds significantly to their workflow. By controlling blood pressure and keeping it down, you can avoid such problems, as well as heart attacks.

Be aware you can only access Indapamide if you have been prescribed it by a doctor. It can potentially interact with other drugs you take and can cause a number of unwanted side effects. Your doctor can assess the extent of your condition to decide whether this is indeed the most suitable medicine for you.

Condition(s) treated

  • Hypertension

Type of medicine

  • Tablet

Side effects

As well as having its intended effect of reducing high blood pressure, it is possible that Indapamide can cause you to experience other side effects as well. Below is a list of the more severe side effects you may experience whilst taking Indapamide. If you notice any of these at any time, then you should contact your doctor immediately and seek emergency medical assistance.

Symptoms and signs of an imbalance of potassium or water in your body

  • Irregular heartbeat


As well as these more serious side effects, there are others you may experience which are less of a cause for immediate concern. Instead, you may find that the following side effects will pass over time as your body adjusts to the medicine. However, if you do experience any of the following and find them lingering or bothersome, then you can still contact your doctor. They may be able to advise on ways to reduce the effects, such as by altering the doses of Indapamide that you take.

Rare or less common

  • Loss of appetite

You may experience other side effects that have not been listed here. If this is the case, and you have any questions about what you are experiencing, then you can contact your doctor. Again, they may be able to advise on ways to reduce your side effects or to make them more manageable.


Below you can find the typical doses of Indapamide that are prescribed to patients in order to help lower blood pressure. Be aware that your exact prescription may be a lot different from what is listed below. This is because each patient is different and requires a different amount of medicine to help treat their condition. You should therefore follow the exact prescription as given to you by your doctor. You should only ever alter your doses if you have been told to do so by your medical professional.

  • Adults. Take 2.5 to 5 mg once per day.

You may find that Indapamide gives you an unusual feeling of tiredness once you first start taking it. You may also notice that you more frequently urinate, or pass more urine when you do urinate. You may find that these effects lessen over time as you take more of the medicine. To help stop this increase in urine from affecting the way you sleep, here are some tips to follow.

  • If taking a single dose each day, take it after breakfast in the morning.

If you have the flexibility, then you should plan to take your doses on a schedule that least affects your sleep or personal activities. Your doctor can advise further on the best time to take this.

You should always try to remember to take this medicine, and to help with this you should take it at the same time(s) every day.

Here are some further pieces of advice for taking this drug to help relieve high blood pressure:

  • You should follow all other guidance your doctor has offered, as well as taking this medicine. This may include steps to help control your weight, such as by reducing certain types of food in your diet, notably sodium. Your doctor can advise on the best changes to your diet. If you wish to make any other alterations, you should first discuss these with your doctor.

To help treat your hypertension as best as possible, you should remember to take this medicine every day as scheduled. If you do miss a dose for any reason, you should take it as soon as possible. However, if it is almost time for the next scheduled dose, you should skip the missed one. This is because it is important you do not double dose.


It is possible that Indapamide will interact with other drugs you are currently taking. These interactions are usually avoided where possible, as they can affect your treatment. However, in other cases it may be necessary for an interaction to occur. In either case, your doctor may wish to alter one or both drugs that interact, or at least change the doses you receive of one or both. Your doctor is best placed to advise on any unwanted interactions that may occur. For this reason, you should inform them of any prescription and nonprescription drugs you are currently taking. Directly below is a list of drugs with which it is usually not recommended you take at the same time as Indapamide. However, if they are required to both be taken, then your doctor may well alter the doses of either one or both medicines.

  • Dipyrone

If you take Indapamide at the same time as any of the following drugs, then you may be at an increased risk of experiencing certain side effects. However, it may still be better for your treatment to take both medicines. Your doctor may, therefore, alter your doses, or how frequently you take either medicine.

  • Licorice

As well as interacting with drugs, it is possible that Indapamide will interact with certain parts of your typical dietary intake. Your doctor may, therefore, ask you to make changes to what you smoke, eat, or drink. For example, it may be necessary for you to start smoking less tobacco or drinking less alcohol. If you are advised on making any alterations to your diet, you should follow them carefully.

Finally, it is possible that Indapamide will interact with other medical problems you suffer from. You should inform your doctor of your full medical history so they can decide if any such interactions are likely to occur. Below is a list of medical problems which are known to interact more severely with this medicine.

  • A history of gout. This drug could make this condition worse


Before prescribing you with this medicine, your doctor will first need to examine you to ensure this is indeed the most suitable drug for your needs. As a part of this examination, they will need to understand any other allergies you currently have. This includes allergies to dyes, animals, preservatives, or to foods.

As of writing, there are no pediatric-specific studies that have been carried out using this drug. The only studies that have taken place have been on adult patients. This means that it is unclear as to whether Indapamide would affect younger patients differently to older ones.

Elderly patients taking Indapamide are more likely to suffer from symptoms and signs of too much potassium loss, as well as lightheadedness and dizziness. This is because older patients are more sensitive to the effects of this medicine as compared to younger adults.

As of writing, it appears that some studies have been carried out on either pregnant women or pregnant animals. It is unclear as to whether there are any abnormal effects on the fetus. Instead, your doctor will be able to advise whether or not this is a suitable drug to take whilst pregnant. If you do become pregnant whilst taking this medicine, you should inform your doctor.

There are currently no suitable studies that have been carried out on the use of Indapamide on breastfeeding women. Again, your doctor is best placed to advise on any increased risks and then weigh these against the benefits with you.

Your doctor will wish to schedule regular appointments whilst you are taking this medicine. This is so they can track the progress of your condition and make any necessary adjustments to your prescription.

It is possible that Indapamide will cause your body to lose potassium. To help prevent this, your doctor may advise you do the following.

  • Drink or eat foods that contain high levels of potassium (such as oranges or other citrus fruits)

You should follow these directions carefully if they are given to you. Similarly, you should not change any other aspects of your diet without first discussing changes with your doctor. This is even more important if you currently take a potassium supplement or medicine if you have a special diet (such as for type 2 diabetes). In such cases, it may not be necessary for you to take extra potassium, and it may, in fact, be harmful.

If you suffer from continuing or severe vomiting, become sick, or have diarrhea at any time whilst using this medicine, you should inform your doctor. This could cause you to lose extra potassium or water.

You should not take any other medicines at the same time as Indapamide unless they have first been cleared by your doctor. This includes prescription and nonprescription drugs. Most notably, this includes medicines to treat the following conditions, as they can increase blood pressure levels.

  • Sinus problems


You should store this medicine is a sealed container and keep it away from children. Never allow it to freeze, and keep it away from moisture, heat, or direct light. Once it is no longer needed, or if it goes out of date at all, dispose of this medicine safely and sensibly. Your doctor or pharmacist can advise on ways to do this.


If you are suffering from hypertension, it is vitally important that you start a suitable course of treatment to lower your blood pressure and keep it there. Failure to do so can lead to some very serious health complications. Indapamide is just one drug that can be prescribed to patients suffering from high blood pressure and works by reducing the levels of water in your blood. It is possible you will be prescribed other drugs alongside this one in order to best treat your condition.

You should closely follow all guidance your doctor gives you regarding how you take this drug and any others. They may also advise on multiple dietary and lifestyle changes you should make. These are just as important in helping to relieve your high blood pressure and keep it safely low. Above, you can find full details regarding the possible side effects this drug may cause. If you experience any of the more worrying signs, or if you have any other questions at any point regarding your treatment, you should address these to your doctor.