Indocyanine Green (Intravenous)

Indocyanine green is an injection of a medical dye that is used during tests to help discover liver function, cardiac output, and blood flow to the liver. It's also used to assist specific areas of the eye to allow it to gain visibility during different medical procedures like an angiography. You cannot take this medication on your own, so do not try to obtain it. It will be given to you by or under the supervision of a medical professional such as your doctor. This product is available in the dosage form of powder for solution.

Conditions treated

  • Studies of the function of the heart

Type of medication

  • Powder for solution

Side effects

Along with the intended effects of this medication, its usage could produce some unwanted side effects. Not all of these may be present at one time, however, if they do occur, you may need to seek medical attention.

Consult with your healthcare professional or doctor right away if you experience any of the side effects listed below whilst taking this drug:

Incidence not known

  • Dizziness

You may suffer from side effects that are not mentioned above. You should contact your doctor or healthcare professional if you notice anything strange or unusual. You can report all side effects to the FDA on 1-800-FDA-1088.

Dosage

The final dose of any medication is dependent upon a number of different individual factors and the specifics of the drug in question. Your doctor will take into account your weight, age and height, any other medical conditions you currently suffer from and any medications you take to treat them. They will also consider medications you have taken in the past and any medical conditions that run in the family history. Your doctor will base your dose on the specific conditions you are being treated for, the duration of treatment, the strength of the drug and your reaction to the first dose. This drug is given in a clinical setting under the supervision or by a healthcare professional.

Your doctor or another trained health professional will give you this medication in a clinical setting. You will not need to worry about specific doses. This medication is given through a needle placed in a vein usually in your arm.

As a guide, these are the typical guideline doses for those receiving this injection.

The typical doses of this drug for Injection are as follows:

  • Adults patients - 5.0 mg
  • Children patients - 2.5 mg
  • Infant patients - 1.25 mg

These doses of the dye are typically injected in volumes of 1 mL. An average of 5 dilution curves is recommended in the performance of a diagnostic check of heart output, liver function, and blood flow. The total dose of this drug injected should be kept below two mg/kg.

Interactions

This drug can interact with other drugs. These interactions can cause severe side effects and reduce the effectiveness of either drug in its treatment. To help limit the possibility of interactions, it's important that you give your doctor or healthcare professional a full list of all the current medications you are taking. This should include all over the counter medications, prescription and nonprescription drugs, herbal products and remedies and all vitamin supplements. You should also make your doctor aware of any other medical conditions you may suffer from (including those in your family history) as this may also increase your risk of interactions.

In most cases, your doctor will try to avoid interactions by avoiding treatment with the drug in question, but in some cases, it may still be necessary to risk interactions as it's the best treatment plan for you. Let your doctor know if you are taking any of the following medications alongside Indocyanine Green:

  • Heparin Sodium (heparin)

Other Interactions

Some medications cannot be used at or around the time of eating food or specific types of food since the risk of interactions is increased. The use of tobacco or alcohol or with some medications can also increase the risk of interactions occurring. You should discuss with your doctor or healthcare professional about the use of this medication alongside tobacco, food or alcohol.

Other Medical Problems

The presence of other medical conditions can affect the use of this medication. Ensure you let your doctor know if you suffer from any other medical conditions, especially:

  • Allergy to iodides or a history of: This medication should not be given to those with this allergy. This medication contains sodium iodide which could increase the risk of an allergic reaction occurring.

Warnings

Before deciding to use any drug or medication, there are a number of different factors you need to consider. Below are some considerations to take into account before you commit to the use of this drug.

Allergies

Let your doctor know if you have ever suffered from an unusual or allergic reaction to this drug in the past or similar medications. You should also make your doctor aware of any other allergies you suffer from including to animals, dyes, preservative, and foods. This drug contains sodium iodide which can cause an allergic reaction to anyone who suffers from this allergy.

Pediatric population

Appropriate studies have not been conducted on the relationship of age to the effects of indocyanine green injection in the younger population. Therefore efficacy and safety have not yet been established.

Geriatric population

Appropriate studies conducted to date have not indicated a geriatric-specific problem that could limit the usefulness of indocyanine green injection in the older population.

Use in pregnancy and breastfeeding

You should only use this drug when necessary if you are pregnant. You should let your doctor know if you are currently pregnant or intend on becoming pregnant in the near future.

There are no adequate studies in women that determine infant risk when using this drug whilst breastfeeding. You should, therefore, discuss with your doctor or healthcare professional and weigh the potential benefits against the potential risks before commencing to take this drug whilst breastfeeding.

It's extremely important that your doctor monitors your progress to make sure this medication is working correctly. Your doctor may conduct urine tests to monitor for unwanted effects.

This medication can cause a serious type of allergic reaction known as anaphylaxis. This can be life-threatening and requires urgent medical attention. Inform your doctor right away if you suffer from any of the following signs or symptoms:

  • Itching

Ensure your dentist or doctor who treats you is aware that you are currently using this medication. This is because this medication can affect the test results of certain medical tests.

Don't take other medications unless they have been discussed with your healthcare professional or doctor. This includes prescription and nonprescription medications, vitamin supplements and herbal products. To do so could increase your risk of side effects and interactions.

Storage

This medication will be stored in a clinical setting such as a hospital and you will not need to worry about storage at home. Typically injection medications are refrigerated and kept away from direct light, heat, and moisture.

Summary

When used correctly, Indocyanine Green is successful in determining heart output, liver function and blood flow in the liver alongside assisting visibility in the eye during medical procedures. This drug is given in a clinic setting under the supervision of a doctor or healthcare professional. You will typically be given this drug via injection into a vein in your arm.

The safety and efficacy of this drug have not been established in the use of children. There are no overall reported differences in effectiveness or safety that have been observed between the younger population and the elderly population. This drug does contains "live" agents which could cause an allergic reaction, it's therefore important that you make your doctor aware of any allergies you may suffer from. You should let your doctor know if you are pregnant before using this drug and you should weigh up the potential benefits and risks alongside your doctor before breastfeeding whilst using this drug. If you require any further information about the practical uses of this medication, or you have any questions or queries, then get in touch with your local healthcare professional or doctor for further advice.