Insulin Aspart, Recombinant (Subcutaneous)

Overview

Insulin Aspart is a form of insulin that is fast-acting. Insulin, in general, is one of many different hormones which help your body to turn food into energy. This process works by turning the sugar (glucose) in your blood into fast energy. A secondary function insulin has is helping us to store energy for future use.

However, if you suffer from diabetes mellitus, then your body is unable to create enough insulin, or simply does not use it properly. You must, therefore, take extra insulin in order to properly regulate blood sugar levels and maintain proper health. Having too much sugar in your blood can be very harmful to your health. You should generally take Insulin Aspart with a longer-lasting insulin as well.

Be aware, you can only obtain Insulin Aspart if you have a prescription from your doctor.

Condition(s) treated

  • Diabetes mellitus

Type of medicine

  • Solution

Side Effects

As well as having its intended purpose, it is possible that Insulin Aspart will cause certain patients to experience unwanted side effects. Directly below is a list of the more serious side effects that may occur after using this medicine. If you experience any of the following, then you should contact your doctor immediately.

More common

  • Difficulty thinking

Less common or rare

  • Weak or fast or pulse

It is possible that you will experience no side effects as well whilst taking this. It is also possible that you could experience side effects not listed here. If that is the case, then you can contact your doctor for advice on how to proceed or how to help reduce the unwanted side effects.

Dosage

The required dosage for each patient using Insulin Aspart will depend on a wide variety of factors. It can vary based on your current blood sugar readings, and you will need to make constant adjustments over time. This process may become more straightforward over time as you better understand how your body reacts to this insulin. You should be careful in following the exact dosages your doctor gives you. This is especially important when you fast starting using this and are unsure exactly what effect it can have on your blood sugar levels.

  • Adults. The dose you take will be based on your blood sugar levels, and your doctor can help you determine a suitable amount.

If you miss a dose of this medicine at all, then you should contact your doctor or pharmacist for advice on how to proceed.

Insulin Aspart is given via a shot under your skin. It is possible that your doctor will give you this in a medical setting. They will also likely need to teach you how to give this yourself. You should be careful in following all instructions they give you. You should ask any questions you have before injecting this on your own.

Before injecting, always first check the dose and concentration of the insulin. These two things are not the same. The concentration refers to how many units of this insulin are present in each ml, for example, 100 units/ml. Be aware this doesn't mean you use 100 units at a time. On the other hand, dose is how many units of insulin you will actually use.

You will find a patient information sheet with any package of Insulin Aspart you receive. You should read this sheet carefully and properly understand each of the following points. You can ask your doctor if you have any questions.

  • How and when should you change the insulin in the external insulin pump reservoir, and also change the cartridge adapter and the infusion set

When you inject each time, it is best to use a different part of your body. For example, they could be under the skin of your buttocks, stomach or abdomen, upper arm, or thigh. If you need any help with this aspect of managing your diabetes, you should contact your healthcare professional.

If you are using Insulin Aspart for mealtime insulin, then you should take it immediately before a meal or 5 to 10 minutes before.

If you are using this in an insulin pump, you should be careful in reading all instructions from the pump manufacturer. It should never be diluted or mixed with any other insulin inside of a pump. You should change any Insulin Aspart in your pump at least once each 6 days. You should change the insertion site at least every 3 days. You should contact your pharmacist or doctor if you are unsure as to how to properly use your insulin pump.

Your doctor may also prescribe you with a special meal plan. This meal plan is very important in helping you to better control your condition. Following it closely will allow the insulin you take to work more effectively. You should be sure to test your urine or blood sugar as necessary and to get plenty of exercise.

You should check with your doctor first before you ever mix Insulin Aspart with other types of insulin. You will normally have to do such injections separately. You can discuss any other questions relating to this with your doctor or pharmacist.

You should not change the dose, type, or brand of your insulin without first checking with your doctor. Whenever you receive a new supply of insulin, check all labeling carefully to ensure it is the correct type.

Interactions

It is possible that Insulin Aspart will interact with other drugs you are currently taking. This is why you should inform your doctor of all drugs you are currently taking, both prescription and nonprescription. It is likely that your doctor will want to avoid interactions wherever possible, and this may mean changing certain drugs that you take. Or in other cases, an interaction between two medicines may still be necessary as it is in the best interests of your treatment. Under such circumstances, your doctor may need to alter the doses you receive of one or both medicines. Below is a list of drugs with which it is usually not recommended you take at the same time as Insulin Aspart. Again, however, it may be necessary to do so. Though your doctor is best placed to decide the best course of action.

  • Enoxacin

If you take Insulin Aspart at the same time as any of the following medicines, then you may be at an increased risk of experiencing certain side effects. Although, it may still be best for you to take both. If so, your doctor may alter your doses in some way.

  • Esmolol

As well as interacting with other medicines, it is possible that Insulin Aspart could interact with certain parts of your daily dietary intake. In order to avoid such interactions, your doctor may advise you make certain adjustments to your diet. This could mean changing what you smoke, eat, or drink. You should follow your doctor's guidance as closely as possible. In particular, Insulin Aspart is known to interact with the following. Your doctor may give you guidance on consuming the following.

  • Ethanol

Finally, it is possible that Insulin Aspart will interact with other medical problems you have, or have had in the past. You should inform your doctor of your complete medical history. In particular, the following are known to interact with this medicine.

  • Hypokalemia (low potassium in your blood). Insulin Aspart may make this condition worse, as well as increasing your chance of experiencing serious side effects

Warnings

Before prescribing you with this medicine, your doctor will want to ensure it is a part of the most suitable course of treatment for your diabetes. As a part of this process, your doctor will need to be made aware of any allergies you have. This can include allergies to animals, dyes, foods, and preservatives.

The suitable studies that have so far been performed have not highlighted and pediatric-specific problems that would make Insulin Aspart less useful in child patients. However, no efficacy and safety have yet been established in children for the use of Insulin Aspart mix 70/30 and 50/50.

As of writing, suitable studies into the geriatric population have not been performed. However, it is not expected that this medicine would be any less useful in geriatric patients than what it would be in younger adults. Though it is worth noting that older patients are more likely to suffer from age-related kidney, liver and heart problems. If this is the case, then the doses a patient takes may need to be adjusted.

As of writing, it appears some studies have taken place on either pregnant animals or pregnant women, but it is unclear as to what the results were. If you are pregnant now, or if you become pregnant whilst using Insulin Aspart, inform your doctor. It may be that they need to make certain adjustments to your treatment.

As of writing, there are no suitable studies that have taken place in breastfeeding using Insulin Aspart. Yoru doctor is best placed to advise you of any increased risks and then weigh them with you against the benefits of using this medicine.

You should never, under any circumstances, share insulin cartridges or pens with another patient. Sharing a pen with more than one person is in no way safe. By using needles with others, you are at risk of transmission of HIV, hepatitis, and other bloodline illnesses.

Your doctor will want to see you at regular appointment throughout your treatment. It is important you attend these so your doctor can monitor your health and make any necessary adjustments to your treatment.

Below is some more guidance your healthcare team is likely to give you. You should follow it closely:

  • Travelling. You should keep a recent prescription with you at all times. You should prepare for emergencies away as you normally would. Take into consideration other factors, such as time zones. This can help you keep meal times as close to usual as possible.

Emergencies can occur due to your diabetes.Here is some further guidance you should follow to ensure you are best prepared for such occasions:

  • Always wear a medical ID neck chain or bracelet. You should also carry an ID card inside of your purse or wallet which states that you have diabetes and lists all medicines you require.

It is possible that Insulin Aspart will cause you to have a serious allergic reaction. This requires immediate medical attention as it can be life-threatening. If you experience any of the following symptoms at any time, contact your doctor immediately.

  • Swelling of the face, tongue, and throat

You may experience swelling, a rash, skin redness, or itching at the site of injection. If you find this irritation does not go away, or if it is severe, then tell your doctor. You should not then inject insulin into an area that is already itchy, swollen, or red.

If you use this drug with other diabetes medicines, then you may experience an edema or heart problems. If you notice any of the following signs at any time, contact your doctor immediately.

  • Having shortness of breath

Taking too much insulin can cause you to experience hypoglycemia. This low blood sugar can also occur if you take Insulin Aspart alongside other antidiabetic medicines, exercise more than usual, can't eat because of diarrhea, vomiting or nausea, miss or delay a snack or meal, or drink alcohol. You should treat the symptoms of low blood sugar or else you may pass out. The exact symptoms you feel may be different to what other people experience. You should try to quickly learn which symptoms you experience and then learn to treat such symptoms as early as possible. Such symptoms of low blood sugar levels include the following:

  • Slurred speech

To treat low blood sugars you can do the following:

  • Drink sugar dissolved in water, fruit juice, or non-diet soft drink

You should also check regularly for low blood sugars. If your symptoms do not improve, then get to a doctor right away. If you experience convulsions or unconsciousness, then those around you should be trained in knowing that they need to call for emergency help. You should have your glucagon kit available, along with the necessary needles and syringe. People should be trained on how to use it, including not just yourself but members of your household.

It is possible you will experience hyperglycemia, which is high blood sugar levels.This can occur if you overeat or don't follow a meal plan, don't exercise enough, skip a dose of your insulin or antidiabetic medicine, or have an infection of fever.

The symptoms of hyperglycemia to look out for include the following:

  • Increased urination

If these symptoms of high blood sugar occur, keep an eye on your blood sugar levels and then call your doctor for further instructions.

Storage

You should store your Insulin Aspart safely away from children at all times. Once you no longer need your medicine, or if you find any of it goes out of date, you should dispose of it safely and sensibly. Your doctor or pharmacist can advise you on how to do so.

You should store all cartridges, pens, and vials in the refrigerator, but do not allow any of them to freeze. You will find an expiration date on all of the medicine which tells you how long you can store them in the refrigerator. Once this expiry date has passed, throw away the medicine.

You can keep your current vial at room temperature in a chilled place or in a fridge for up to 28 days. It must be kept away from light and heat.

You should not refrigerate the pen or cartridge that you are currently using. You should instead keep it at room temperature, away from direct heat, away from light, and in a cool place. You can do this for up to 28 days.

Summary

If you suffer from diabetes mellitus, then Insulin Aspart will likely form a crucial part of your insulin intake. It is used to help keep your blood sugars down and is taken along another insulin that is not fast-acting. Be aware that controlling your diabetes will mean doing more than taking insulin. You will need to follow other dietary and lifestyle guidelines that your doctor will give you. Following this guidance as closely as possible will allow you to better control your blood sugar levels and avoid any unwanted complications.

Yoru doctor will want to schedule regular appointments to meet with you and discuss your condition. It is vital you attend these so they can monitor your progress and make any necessary adjustments to your treatment. Above you can find more details regarding the side effects that may occur if you use Insulin Aspart. If you experience any of the serious effects, then you should contact your doctor immediately. If you have any other questions regarding the use of this medicine or managing your diabetes, you should address these to your doctor.