Ipratropium (Nasal)


Ipratropium is a nasal spray medicine that is given to patients with a runny nose (rhinorrhea). There are two different percentages of this nasal spray. The 0.03% Ipratropium nasal solution is given to patients with a runny nose that has been caused by nonallergic and allergic perennial rhinitis. Be aware that this 0.03% solution spray is not used to relieve post nasal drip, congestion, or sneezing that is caused by nonallergic or allergic perennial rhinitis.

The second variety is the 0.06% Ipratropium nasal solution. This is given to patients for a period of four days if they want to relieve their runny nose that is a result of a cold. Be aware that it is not effective in relieving sneezing or nasal congestion that is caused by a common cold.

Ipratropium nasal spray works by preventing your nasal glands from creating large quantities of fluid. Be aware that you can only access this spray with a doctor's prescription.

Condition(s) treated

  • A runny nose

Type of medicine

  • Nasal spray

Side effects

As well as having its intended effects, it is possible that the Ipratropium nasal spray will cause you to experience certain side effects. These side effects can range in the severity and their need for medical attention. Be aware that you may experience multiple side effects or you may simply experience none. Below is a list of the more serious potential side effects. If you experience any of this whilst taking Ipratropium, you should contact your doctor immediately.

For the 0.03% Ipratropium nasal spray

More common

  • Unusual weakness or tiredness

Less common


  • Difficult or painful urination

Incidence not known

For the 0.06% Ipratropium nasal spray that patients use for 4 days

Less common

  • Nosebleeds


  • Difficult or painful urination

Below is a list of the less serious side effects that patients taking Ipratropium nasal spray may experience. If you do experience any of them, then you may find that they simply pass over time as your body adjusts to the medicine. However, if you do find them to be lingering or bothersome then you can still contact your doctor for advice.

For the 0.03% Ipratropium nasal spray

Rare or less common

  • Nasal irritation, itching, or burning

For the 0.06% Ipratropium nasal spray

Rare or less common

  • Increased nasal congestion

Though these lists are extensive, they are not necessarily all-inclusive. This means you may experience other side effects not listed here. If this is the case and you would like to discuss them, then you should contact your doctor.


Below you can find the typical doses prescribed to patients for both the 0.03% and 0.06% nasal sprays. Be aware that the exact doses given to you by your doctor may differ greatly from what is below. That is because every patient is different and your prescription is based on your exact needs. It takes into account factors such as other drugs you are taking and any other medical conditions you may have. You should not alter your doses in any way unless told to do so by your doctor. If you think your dose may need changing, then you should discuss this with your doctor.

For patients taking the 0.03% Ipratropium nasal spray to treat a runny nose caused by nonallergic and allergic perennial rhinitis:

  • Adults, teenagers, and children aged 6 and above. Take 2 sprays in both nostrils two to three times per day

For patients taking the 0.06% Ipratropium nasal spray to treat a runny nose from a common cold:

  • Adults, teenagers, and children aged 5 and above. Take 2 sprays in both nostrils three to four times per day

You should try to never miss a scheduled dose of this medicine, as doing so will ensure the best treatment for you. However, if you do miss a dose for any reason, then you should take it as soon as you remember. This is as long as it is not soon time for your next dose, in which case you should simply skip the missed dose. It is important you do not double dose.

You should take this nasal spray in exactly the way as prescribed by your doctor. Never take it for longer than directed and never take any more of it. Doing so could increase your chances of experiencing certain side effects.

Upon receiving this medicine, you will find patients directions. You should read this fully and address any questions you have to your doctor.

This medicine is only intended for your nose. If you get any in your eyes by mistake, then you should rinse them thoroughly with water and then call your doctor for further assistance.

The time taken to feel better after taking this medicine can vary. Some patients will feel the benefits immediately, whereas for others it may take a couple of weeks. For the best results, keep taking this medicine exactly as prescribed by your doctor, regardless of how soon you feel the benefits.

Here is some guidance on using the nasal spray:

  • First, take the green safety clip and plastic dust cap off the pump. This safety clip is there to stop accidental discharge when it is not in use.


It is possible that the Ipratropium nasal spray will interact with other drugs you are currently taking. You should, therefore, inform your doctor of any prescription or nonprescription drugs you are currently taking. They may wish to avoid all possible interactions as this is best for your treatment, However, on other cases, it may be that an interaction is necessary as it is important for your treatment that you take 2 interacting medicines. Either way, your doctor can advise on ways to reduce any such interactions.

Below is a list of drugs with which it is usually not recommended you take at the same time as Ipratropium. However, if it is necessary to take both, then your doctor may reduce your doses of one or both in order to limit any interactions.

  • Tiotropium

If you attack any of the following medicines at the same time as Ipratropium, then you may be at greater risk of experiencing certain side effects. Again, if taking both medicines is still in your best interests, then your doctor may need to alter one or both doses.

  • Betel Nut

As well as interacting with drugs, it is possible that this medicine will interact with certain aspects of your dietary intake. Your doctor may, therefore, need to restrict how much or how often you drink, smoke, or eat certain things. For example, it may be necessary for you to drink less alcohol or to smoke less tobacco whilst using the Ipratropium nasal spray.

Finally, this nasal spray may interact with other medical problems you have. you should inform your doctor of any other conditions you suffer from. In particular, point out any of the following if applicable.

  • Liver disease. You should use this medicine with caution as it has not been properly studied in patients suffering from this condition


Before prescribing you with this medicine, your doctor will want to ensure it is the right treatment for you. As part of this decision-making process, they will need to understand the full extent of your current medical condition. A part of this will mean understanding any allergies you have. You should inform your doctor of any allergies you have to dyes, animals, foods, or preservatives.

As of writing, no safety and efficacy have been established for the use of Ipratropium nasal spray in children younger than 6. This is because appropriate studies have not yet taken place.

No information is currently available regarding the specific use of this medicine in older patients. Your doctor is best placed to advise you of any increased risks or effects it may have.

As of writing, it appears that some studies have taken place on other pregnant women or animals using this medicine. However, it is unclear as to whether they demonstrated any increased risks to a pregnant woman or the unborn baby. Your doctor is best placed to advise on any such increased risks.

There appears to be no suitable studies on breastfeeding women using Ipratropium nasal spray. Your doctor is best placed to advise you on any increased risks you may face. You can then weigh these against the benefits of using the medicine.

Your doctor will require you to see them at regular appointments whilst using this medicine. You should attend all of these. Your doctor can then assess how well your treatment is going and make any necessary adjustments to your prescription.

If your condition does not improve, or if it gets worse, during the first few weeks of taking this nasal spray, you should contact your doctor.

It is possible that this nasal spray will cause you to experience a severe allergic reaction, such as anaphylaxis. This reaction requires immediate medical assistance as it is life-threatening. If you notice any of the following symptoms whilst taking Ipratropium nasal spray, you should stop taking it immediately and contact your doctor.

  • Trouble swallowing

If you experience any of the following symptoms whilst taking this spray, you should tell your doctor. They may ask you to visit an ophthalmologist (an eye doctor).

  • Eye discomfort or pain or

Before you perform any dangerous tasks like driving, you should first be aware of how this medicine affects you. In can cause some people to experience difficulty in seeing properly or dizziness.

If you experience unexplained nosebleeds or dryness of your nose, you should tell your doctor right away.

This nasal spray may cause you to have dryness of your throat or mouth. To help relieve the symptoms temporarily you can use a saliva substitute, use sugarless candy or gum, or melt pieces of ice in your mouth. However, if this problem persists for 2 weeks or more, you should inform your dentist or doctor. Having dry mouth continuously can cause an increased risk of fungal infections, tooth decay, gum disease, or other dental decay.

You should not take any other medicines at the same time as Ipratropium nasal spray unless they have first been approved by your doctor. This includes any prescription and nonprescription drugs, as well as any vitamin or herbal supplements.


You should store Ipratropium nasal spray in a sealed container and keep it at room temperature. Do not expose it to direct light, moisture, or heat and do not let it freeze. You should also store it somewhere where children cannot reach it. Once you have finished your treatment, or if you find any medicine goes out of date, you should dispose of the medicine. Your doctor or pharmacist can advise you on the proper way to dispose of it.


If you are suffering from a runny nose, then either the 0.03% or 0.06% version of this nasal spray could be very beneficial for you to use. Just be aware that it is not suitable for everyone and is only available through a prescription. This is because it is known to interact with a variety of other drugs and medical conditions and can cause unwanted side effects. Yoru doctor will be able to advise you on the correct spray to take and the correct way to use it in order to avoid these unwanted effects.

Be aware that you should only use this medicine in exactly the way that your doctor tells you to. If you ever feel like you need to take more of it or to take it more often, then you should first discuss this with your doctor. Above, you can find full details regarding the possible side effects that may occur after using Ipratropium nasal spray. If you experience any of the more severe ones or would like to discuss your side effects, then you should contact your doctor. Similarly, any other questions about this medicine or your condition should be addressed to a trained medical professional.