Ketoprofen (Oral)

Ketoprofen treats osteoarthritis and rheumatoid arthritis inflammation, helping to relieve the pain.


Ketoprofen is an analgesic (painkiller) and antipyretic (fever reducer), both compounds found in nonsteroidal anti-inflammatory drug (NSIAD). This medicine is not a cure for the ailment, but it works to relieve the pain of acute and chronic arthritis.

This medicine is safe and effective when taken as prescribed by the doctor. Side effects vary from person to person, dependent on the dosage, frequency and duration.

  • Taking an excessive dose will increase the chances of unwanted side effect in elderly patients.
  • If you are pregnant, this medicine could harm the unborn baby.

If you suffer or have a family history of these disorders' tell the doctor. NSAIDs are associated with causing or triggering serious or fatal health events. They are involved in twenty-five percent of adverse drug reactions for these disorders. If you have been taking NSAIDs, the risks increase.

  • Cardiovascular
  • Gastrointestinal
  • Respiratory
  • Renal functions

Conditions Treated

  • Pain

Type Of Medicine

  • Nonsteroidal anti-inflammatory

Side Effects

Varying levels of side effects will occur when taking ketoprofen. The side effects associated with this medicine range from mild to serious. If you are taking other medicines, the effects or the condition itself could worsen.

Be sure to share all of your health, medical and family history with your doctor. The information will help in predicting how you may react to this medicine. If you have allergies, be sure to tell the doctor, this medicine could worsen the reaction.

Here's a list of the most common, least common, and rare side effects that have occurred with this medicine. In most cases, once your body adjusts to the medicine, they will fade away. If you experience any of these effects beyond your own comfort level, talk to your doctor. If the effect worsens or persists beyond a week, contact your doctor immediately.

Most Common

  • Bloated
  • Change in blood pressure
  • Fatigue
  • Gas
  • Headache
  • Insomnia
  • Irritability
  • Nausea
  • Pain
  • Thirst
  • Vomiting
  • Weight gain

Not all side effects need medical attention - talk with the doctor if the side effects are uncomfortable, there are methods to help ease the effect. DO NOT stop taking any of your prescribed medicines without your doctor's approval.

Least Common

  • Bladder pain
  • Cloudy urine
  • Double vision
  • Hearing loss
  • Rash
  • Ringing in the ears
  • Shaking
  • Swelling of the mouth
  • Weight loss

Some effects are rare, but introducing new medications can prompt them. Sometimes, adjustments made to existing medicines or a hidden health condition can instigate the side effect. DO NOT ignore any of the symptoms - tell the doctor.


Adverse Effects

If you suffer from any disorders and take prescription medicines for treatment ' let your doctor know. Sometimes, when two different medicines are taken together, the doses and the scheduled times for taking them need to be adjusted to treat both conditions and avoid side effects.

Prescription medicines or over-the-counter (OTC) treatments, health supplements, herbal remedies can cause side effects. Lifestyle choices about alcohol, tobacco, exercise routines and specific foods affect your body's response to medications. It could change how you respond to this medication.


The doses listed are averages. Doses vary depending on the severity of your condition, other health circumstances or your own tolerance to this medication. Your doctor will prescribe the number of doses you should take each day and the time allowed between doses. Take the medicine exactly as instructed by the doctor. If you have questions, ask the doctor or the pharmacist.

Ketoprofen is available in several forms ' each is taken orally. Take this medicine with a full glass of water. If you have a sensitive stomach, talk with the doctor' you may be able to replace the water with food or other liquids to avoid an upset stomach. Medications work best when you take them as scheduled. If you delay or miss a dose, it will take longer to relieve the pain.

  • Capsule
  • Solution
  • Syrup
  • Tablet

For Osteoarthritis and Rheumatoid Arthritis - capsules


  • 75 milligrams (mg) 3 times a day or 50 mg 4 times a day.
  • 300 mg maximum per day

Children' the doctor will decide the dose.

For Osteoarthritis and Rheumatoid Arthritis' extended release capsules


  • 200 mg once a day' morning or evening. Medication should be taken at the same time each day.

Children' the doctor will decide the dose.

For Menstrual Cramps


  • 25 to 50 mg every 6 to 8 hours. Depending on the pain level, the doctor may increase the dose to 75 mg.
  • 75 mg maximum per day ' higher doses will not speed up the relief.

Children ' the doctor will decide the dose.

Missed Dose

If you miss a dose, take it as soon as possible' the only exception'if it is almost time to take the next dose, skip the missed dose and continue with your normal schedule. Contact your doctor about the missed dose. DO NOT double the dose; you could trigger a serious side effect.


In any situation when an accidental or unintended overdose occurs'contact emergency assistance immediately. If a child is involved in this overdose, contact the pediatric poison information center in your area for instructions.


Medicines help to improve our health, and most work well together, yet certain medications when used together have serious or unpleasant interactions. Ketoprofen works effectively with other medications under the supervision of a doctor. Certain medicines will interact with each other, causing secondary disorders or prompting serious effects to existing health conditions.

Some health conditions require the use of multiple medications and doctors will monitor the interactions for any change in effects or increased health risks. Multiple prescriptions may change the outcome of treatment due to the chemical quantities.

If you are taking, any of these medicines listed or you believe you are taking medicines that may share similar ingredients, tell your doctor. There are medications not listed that interact with this medicine.

  • Acebutolol
  • Aceclofenac
  • Acemetacin
  • Alacepril
  • Amitriptyline
  • Amoxapine
  • Apixaban
  • Ardeparin
  • Aspirin
  • Atenolol
  • Balsalazide
  • Bemiparin
  • Benazepril
  • Benzthiazide
  • Betamethasone
  • Betaxolol
  • Bisoprolol
  • Bivalirudin
  • Bromfenac
  • Budesonide
  • Bumetanide
  • Captopril
  • Carteolol
  • Carvedilol
  • Celecoxib
  • Celiprolol
  • Certoparin
  • Chlorothiazide
  • Cilazapril
  • Cilostazol
  • Citalopram
  • Clomipramine
  • Clonixin
  • Cortisone
  • Cyclosporine
  • Dalteparin
  • Danaparoid
  • Deflazacort
  • Delapril
  • Desipramine
  • Desirudin
  • Dexamethasone
  • Dexibuprofen
  • Diazoxide
  • Dibenzepin
  • Diclofenac
  • Dothiepin
  • Doxepin
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Enalapril
  • Enalaprilat
  • Enoxaparin
  • Eplerenone
  • Epoprostenol
  • Eprosartan
  • Eptifibatide
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Floctafenine
  • Fluocortolone
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Fosinopril
  • Furosemide
  • Ginkgo
  • Heparin
  • Hydrochlorothiazide
  • Hydrocortisone
  • Ibuprofen
  • Iloprost
  • Imidapril
  • Imipramine
  • Ketorolac
  • Labetalol
  • Lepirudin
  • Levobunolol
  • Lisinopril
  • Lithium
  • Lofepramine
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Melitracen
  • Meloxicam
  • Mesalamine
  • Metipranolol
  • Metolazone
  • Metoprolol
  • Milnacipran
  • Moexipril
  • Nabumetone
  • Nadolol
  • Nadroparin
  • Naproxen
  • Nebivolol
  • Nefazodone
  • Nepafenac
  • Niflumic Acid
  • Nortriptyline
  • Olmesartan
  • Olsalazine
  • Opipramol
  • Oxaprozin
  • Oxprenolol
  • Parecoxib
  • Parnaparin
  • Paroxetine
  • Pemetrexed
  • Penbutolol
  • Pentopril
  • Perindopril
  • Phenindione
  • Phenprocoumon
  • Phenylbutazone
  • Piketoprofen
  • Pindolol
  • Piroxicam
  • Polythiazide
  • Practolol
  • Prednisolone
  • Prednisone
  • Proglumetacin
  • Propranolol
  • Propyphenazone
  • Proquazone
  • Quinapril
  • Ramipril
  • Reviparin
  • Rivaroxaban
  • Rofecoxib
  • Salicylic Acid
  • Sertraline
  • Sulfasalazine
  • Sulindac
  • Tacrolimus
  • Telmisartan
  • Temocapril
  • Tenoxicam
  • Tianeptine
  • Ticagrelor
  • Ticlopidine
  • Timolol
  • Tinzaparin
  • Tirofiban
  • Tolmetin
  • Torsemide
  • Trandolapril
  • Treprostinil
  • Triamterene
  • Trimipramine
  • Valdecoxib
  • Valsartan
  • Venlafaxine
  • Vilazodone
  • Vorapaxar
  • Vortioxetine
  • Warfarin
  • Xipamide
  • Zofenopril

Existing Health Conditions

Ketoprofen may increase the risk of adverse reactions to an existing condition. Sharing your medical history with the doctor before starting this treatment may help to prevent unwanted effects. If you have recently undergone surgery, your doctor may not recommend this medicine for you.


The U.S. Food and Drug Administration (FDA) posted notices on the use of NSAIDs to protect the public health and offer information for consumers and medical professionals when making health decisions involving drugs or medications.

Ketoprofen may cause serious side effects without warnings. For some individuals, this medicine is prescribed for short durations. It may also be used when individuals do not respond to other NSAIDs.

  • This medicine causes ulcers more frequently than other NSAIDs.
  • It will increase your risk of heart attack or stroke.
  • Bleeding in the stomach or intestines has been reported.

If you have allergies, this medicine is known to instigate a rare allergic reaction called anaphylaxis for individuals with an allergy to aspirin or other NSAIDs. If you experience irregular breathing, fainting or swelling of the face and throat' call for medical assistance immediately.


Keep this medication out of the reach of children or pets. Store this medicine at room temperature, away from heat, moisture and direct light. DO NOT freeze.

  • Ask your doctor or pharmacist how you should dispose of any medicine you do not use.
  • Do not keep outdated medicine or medicine no longer needed.


Overall, this medicine has been effective in controlling pain. A combination of existing health ailments and your response to treatment will affect the outcome. Your doctor may prescribe a higher dose if you suffer from rheumatoid arthritis. Lower doses may be prescribed for osteoarthritis and muscle injuries. The difference between the two conditions is the severity of swelling.