Lacosamide (Intravenous)

Overview

In helping to treat epilepsy, Lacosamide is often prescribed to help control partial seizures. Lacosamide works within a patient's central nervous system and is able to reduce both the severity and quantity of seizures. Be aware that this medicine is only available with a prescription from your doctor. It is known to interact with a variety of other drugs and medical problems, so is only suitable for certain patients.

Condition(s) treated

  • Epilepsy

Type of medicine

  • Solution

Side effects

As well as having its intended effect of helping to control seizures, it is possible that patients taking Lacosamide will also experience other side effects. These side effects can arrange in their severity and their need for medical assistance. In fact, many patients may experience no side effects at all, whereas others may experience a number. Below is a list of the more severe side effects that may occur. If you experience any of the following whilst taking Lacosamide, you should contact your nurse or doctor immediately.

More common

  • Unusual drowsiness or sleepiness

Less common

  • Loss of pleasure or interest

Rare

  • Unusual tiredness

Incidence not known

  • Chills

Instead of these more severe side effects, you may experience less serious ones which don't require medical assistance. Directly below is a list of such side effects. You may find that they pass over time as your treatment progresses and your body adjusts to the medicine. However, if you do experience any of the side effects listed below and find them lingering or bothersome, then you can still contact your doctor or nurse. They may be able to advise on way to reduce the unwanted effects and answer any questions you may have.

More common

  • Seeing double

Less common

  • Sensation of spinning

Incidence not known

  • Dry mouth

You may experience other side effects that have not been listed here. If that is the case, then you can still contact your doctor who can answer any questions or worries you might have.

Dosage

You will not need to worry about the dosage for Lacosamide as it is given in a hospital setting by a trained nurse or doctor. It is administered as a solution and is injected into a vein. Be aware that you will be required to have the IV tube in place for between 15 and 60 minutes as the medicine is injected slowly.

You will likely need to receive a few doses of this medicine over a period of time, before then switching to oral medicine that works in much the same way. If you do have any queries or concerns about this then you can discuss them with your doctor.

You will likely be given a Medication Guide before you receive this injection. You should read this carefully and fully and then address any questions you have to your doctor.

Interactions

It is possible that Lacosamide will interact with other drugs you are currently taking. This is why it is important that you tell your doctor about any other drugs you are currently taking. This includes both prescription and nonprescription drugs. In many cases, your doctor will want to avoid any such interactions as they could alter the effectiveness of your treatment, In other cases, an interaction may be necessary as taking both medicines is best for your health. Directly below is a list of medicines with which it is usually not recommended you take at the same time as Lacosamide. Your doctor may decide to alter one or both medicines to avoid interactions. However, if an interaction is to be expected and best for your treatment, then they may simply alter the dose of one or both medicines.

  • Metipranolol

As well as interacting with other medicines it is possible that Lacosamide will interact with certain aspects of your dietary intake. If this is the case, then your doctor may recommend changes to what you eat, drink, or smoke. For example, you may need to alter how much or how frequently you drink alcohol or smoke tobacco.

Finally, it is possible that Lacosamide will interact with other medical conditions you have. You should, therefore, inform your doctor of your complete medical history. In particular, be aware of the following.

  • A history of mental illness

Warnings

Before prescribing you with this medicine, your doctor will first want to ensure it is indeed safe and suitable for you to take. As a part of this process, they will need to be aware of any other allergies you currently suffer from. This includes any allergies to foods, dyes, animals, or preservatives.

As of writing, no efficacy and safety have been established for the use of Lacosamide in children aged younger than 17. This is because no suitable studies have taken place that have assessed the exact effects the medicine has on children of this age. Instead, your doctor will need to decide as to whether this is a safe and suitable drug for your child to receive.

The suitable studies that have taken place in elderly patients using this medicine have not highlighted any geriatric-specific problems that would make this injection any less useful for older patients. Be aware however that elderly patients are more likely to suffer from age-related liver, heart, or kidney problems.If this is the case then greater caution may need to be exercised when prescribing Lacosamide to such patients.

As of writing, it is unclear as to whether suitable studies have taken place on pregnant women using this medicine. Your doctor is best placed to advise you on any increased risks you may have of taking Lacosamide when pregnant. If you become pregnant whilst taking this medicine, you should make your doctor aware straight away.

As of writing, no suitable studies have taken place on the effects of this medicine on women who are breastfeeding. If there are any increased risks to you or your infant child, then your doctor will need to make you aware of them.

Yoru doctor will need to see you at regular appointments to monitor your condition and see how your treatment is progressing. You should attend all scheduled appointments. Be aware that you may need to have blood tests performed to check for any unwanted effects.

If you do become pregnant whilst taking this medicine, you should inform your doctor straight away. They may want you to join the North American Antiepileptic Drug Pregnancy Registry. Pregnant women using this medicine are usually on this registry.

If, whilst taking Lacosamide, you have unusual behavior or strange thoughts, then you should inform your doctor of this. The changes that some patients experience when taking this medicine are similar to those often displayed in people who have drunk too much alcohol. You may also experience the following symptoms that must be discussed with your doctor right away:

  • Hallucinations (feeling, seeing, or hearing things that are not there)

Lacosamide can cause some patients to experience some of the following effects: drowsiness, sleepiness, trouble thinking, blurred vision, unsteadiness, dizziness, double vision, or clumsiness. As such, you should not perform any dangerous tasks like driving until you know fully how this medicine affects you. If you do experience any of these side effects and find them bothersome, you can discuss them with your doctor.

Lacosamide has the potential to cause changes in the rhythm of your heart. This includes conditions like PR prolongation. Some patients may experience fainting, lightheadedness, a change in their heartbeat, or other serious side effects. If you have any symptoms of heart rhythm problems whilst taking this medicine, you should contact your doctor. Such symptoms include a fast, irregular, or slow heartbeat.

This medicine can cause patients to experience severe allergic reactions that can affect multiple organs, such as the kidney or liver. If you display any of the following symptoms after receiving the Lacosamide injection, inform your doctor immediately:

  • Stomach pain

Storage

You will not be required to store this medicine at any time. It is given in a medical setting by a trained doctor or nurse. It is their responsibility to ensure it is safely stored.

Summary

If you suffer from epilepsy, then Lacosamide injection could be a very useful drug in helping to control both the severity frequency of your seizures. Be aware however that it is only given via a doctor's prescription as it is not suited to certain patients. It has the potential to interact with a variety of medical problems and drugs, and your doctor will need to first ensure it is safe for you to receive it. They may also need to prescribe this medicine alongside others to help your condition.

You should follow all guidance that your doctor gives you with regards to this medicine and any others you need to take. If you experience any of the worrying symptoms or side effects discussed above, then you should inform your doctor immediately. Similarly, if you have any other questions about Lacosamide injection or other aspects of your condition, these are best addressed to your doctor.