Lanthanum Carbonate (Oral)

Overview

Lanthanum Carbonate (Fosrenol) is a prescription drug that's used by people suffering from end-stage renal disease to reduce phosphate levels in the blood. It works by preventing the absorption of phosphate by the body, allowing phosphate to be eliminated from the body.

High phosphate levels in your blood can cause difficulties in the absorption of calcium, leading to serious medical problems.

Lanthanum Carbonate comes in the form of a chewable tablet. It's normally taken with meals or immediately after. Please crush or chew the tablets thoroughly before swallowing.

Lanthanum is available under the brand name Fosrenol and is a part of the class of medications known as phosphate binders.

Lanthanum Carbonate is only available with a physician's prescription and may be used for other reasons. For more information about this, ask your pharmacist or doctor.

Common Lanthanum Carbonate side effects include diarrhea, vomiting, and nausea.

Conditions Treated

  • Renal oteodystrophy and hyperphosphatemia

Type Of Medicine

  • Phosphate binder

Side Effects

Aside from its helpful effects, Lanthanum Carbonate may cause some undesirable effects. While not every side effect listed below may happen, if they happen they might require medical attention.

Check with your physician at once if you experience any of the following effects:

Incidence unknown:

  • Troubled breathing
  • Loss of appetite
  • Bone pain
  • Rash or itching skin
  • Convulsions
  • Difficulty with passing stools
  • Unusual weakness/tiredness

Get emergency medical assistance if any of these overdose symptoms occur:

  • Vomiting
  • Nausea
  • Headache

Some Lanthanum Carbonate side effects may happen that normally don't require treatment. These effects may clear during treatment as you adapt to Lanthanum Carbonate. In addition, your healthcare specialist may recommend ways to relieve or prevent some of the effects below. Consult your healthcare specialist if any of the effects below persist, if they're troublesome, or if you've got any queries about them.

More common:

  • Abdominal/stomach pain

Incidence unknown:

  • Tooth injury
  • Belching
  • Indigestion
  • Heartburn
  • Stomach upset/discomfort

Other Lanthanum Carbonate side effects not named above may occur in some people as well. If you develop any other effects, see your healthcare specialist promptly.

Dosage

To prevent adverse effects, you should use Lanthanum Carbonate exactly as instructed by your healthcare provider. Do not misuse or overuse this medication and don't take it beyond the prescribed duration. Read all of the directions in the drug guide.

The dose of Lanthanum Carbonate your physician recommends may depend on your response to the drug and the level of serum phosphate in your body.

The recommended range of dose of this medication is 1500-3000 milligrams per day.

Lanthanum Carbonate should be used with meals in order to boost its absorption by the digestive system. Before using the tablet, chew or crush it thoroughly in your mouth. Don't swallow the tablet whole.

You can take the oral powder variety of Lanthanum Carbonate after peppering it over applesauce or other similar food. Mix the medication and use it instantly. Don't mix the medication with any liquid, including water. Follow the diet program created by your healthcare provider.

If you're using any other drug besides Lanthanum Carbonate, use it at least an hour before or a couple of hours after using Lanthanum Carbonate. If you've got any questions about the right timing of medication, ask your healthcare provider.

Lanthanum Carbonate may make it more difficult for the body to take in other drugs you take orally (by mouth).

  • If you also use thyroid medication, use it at least a couple of hours before or after you use Lanthanum Carbonate.
  • If you use an antibiotic, including Levofloxacin (Levaquin) or Ciprofloxacin (Cipro), use it at least an hour before or four hours after you use Lanthanum Carbonate.
  • Avoid using an antacid within a couple of hours before or after you use Lanthanum Carbonate.

It may be advisable to avoid using any other drugs orally for several hours after or before you use Lanthanum Carbonate.

Don't skip any dose of Lanthanum Carbonate. The dose of Lanthanum Carbonate varies according to each person's condition. The number of Lanthanum Carbonate doses a day, the interval between Lanthanum Carbonate doses and the duration in which you use Lanthanum Carbonate depends on your specific condition and all of these things should be determined only by your healthcare provider. Follow all of your healthcare specialist's instructions and carefully read the label as well.

Interactions

Tell your healthcare specialist about all the drugs you take, such as prescription and over-the-counter drugs, herbal supplements, and vitamins.

  • Especially inform your healthcare specialist if you use:
  • Theophylline (Theochron, Theo-24, Uniphyl, Elixophyllin)
  • Digoxin (Lanoxin, Lanoxicaps, Digitalis)
  • Cyclosporine (Gengraf, Sandimmune, Neoral)
  • Levothyroxine (Levothroid, Synthroid)
  • Sirolimus (Tacrolimus/Prograf, Rapamune)

A blood thinner like Warfarin (Jantoven, Coumadin)

An antibiotic like Ofloxacin (Floxin), Norfloxacin (Noroxin), Moxifloxacin (Avelox), Levofloxacin (Levaquin), Gemifloxacin (Factive), or Ciprofloxacin (Cipro)

An antibiotic like Minocycline (Solodyn, Minocin, Dynacin), Doxycycline (Vibramycin, Periostat, Oracea, Doryx), or Tetracycline (Tetracap, Panmycin, Sumycin, Brodspec, Ala-Tet)

Seizure medications like Valproic Acid (Depakene), Divalproex (Depakote), Carbamazepine (Tegretol, Equetro, Carbatrol), or Phenytoin (Dilantin)

Blood pressure/heart medications like Verapamil (Verelan, Isoptin, Covera, Calan), Quinidine (Quin-G), Procainamide (Pronestyl, Procan), Nifedipine (Procardia, Nifedical), Disopyramide (Norpace), Diltiazem (Cardizem, Cartia), Amlodipine (Caduet, Norvasc, Lotrel, Exforge, Amturnide, Twynsta, Tribenzor, Tekamlo), and others

This list of drug interactions is incomplete and Lanthanum Carbonate can interact with other drugs. Inform your healthcare specialist about all drugs you use, including over-the-counter, prescription, herbal products, and vitamins. Don't start taking any new drug without letting your doctor know.

Warnings

Before you begin using any medication, make sure to report to your healthcare specialist any allergies or medical problems you have, any drugs you're using, whether you're breastfeeding or pregnant, as well as any other vital details about your health. The following factors can affect how you take Lanthanum Carbonate.

Pregnancy'the efficacy and safety of Lanthanum Carbonate haven't been determined in pregnant women. This medication should not be used during pregnancy.

Breastfeeding'it is unclear whether Lanthanum Carbonate comes into contact with human milk. If you're using this medication and are breastfeeding an infant, it may harm your little one. Discuss with your physician whether you should keep breastfeeding or not.

Children and teens'the efficacy and safety of taking Lanthanum Carbonate haven't been determined for children and teens younger than 18.

Bone conditions'Lanthanum Carbonate has been proven to build up in bones and body tissues. There's scant information to ascertain whether Lanthanum Carbonate affects the quality of your bones after more than two years of treatment.

Liver disease'the efficacy and safety of Lanthanum Carbonate haven't been determined in people with reduced liver function. If you've got liver disease or decreased liver function, discuss with your healthcare specialist how Lanthanum Carbonate may affect your condition, how your condition may affect the efficacy and dosing of Lanthanum Carbonate, and whether you require any special monitoring.

Stomach problem'Lanthanum Carbonate may result in severe bowel blockage or obstruction. To decrease this risk, chew the tablets thoroughly. The efficacy and safety of Lanthanum Carbonate haven't been determined for people with Crohn's disease, ulcerative colitis, or peptic ulcer. If you suffer from any of the above conditions, discuss with your healthcare specialist how Lanthanum Carbonate may affect your condition, how your condition may affect the efficacy and dosing of Lanthanum Carbonate, and whether you require any special monitoring.

X-ray'before taking a stomach or abdomen X-ray, tell the people doing the X-ray that you're taking Lanthanum Carbonate.

Surgery'before you have any surgery, inform your dentist or doctor about all the medicinal products you're taking, such as prescription and nonprescription drugs, vitamins, and herbal products.

Regular follow-up is vital during and after your treatment with Lanthanum Carbonate because this medication is normally used for a long time. It's important to have your doctor check your progress and ensure that there are no adverse side effects from taking Lanthanum Carbonate.

Contact your healthcare specialist if your symptoms haven't gotten better even after going through the entire course of treatment. Your healthcare provider may order some blood exams in order to find out the levels of the medication in your blood. Lanthanum Carbonate may affect the results of some medical tests such as an abdomen X-ray.

Avoid using any other drug unless you've thoroughly discussed it with your healthcare specialist. Always consult your healthcare provider before taking any nonprescription, prescription, or herbal medication.

Storage

You should keep Lanthanum Carbonate at room temperature in a sealed container, away from direct light, heat, and moisture. Protect Lanthanum Carbonate from freezing.

Keep Lanthanum Carbonate beyond the reach of kids and don't store outdated or expired medications, or medications you no longer use.

Ask your healthcare specialist how to safely get rid of any medication you don't use.

Summary

You shouldn't take Lanthanum Carbonate if you've got allergies to it or any of the ingredients in it, or if you've got severe constipation or bowel obstruction, or if you've got low phosphate levels in your blood (hypophosphatemia).

Before you use Lanthanum Carbonate, inform your doctor if you've got a stomach ulcer, diabetes, Crohn's disease, ulcerative colitis, any kind of bowel obstruction/blockage, or any history with intestinal surgery or colon cancer.

You should completely chew the Lanthanum Carbonate tablet before swallowing it.

Take Lanthanum Carbonate immediately after eating or take it with food.

Inform your healthcare specialist about all other drugs you take, especially antibiotics, blood pressure or heart medications, a blood thinner, or seizure medications.

If you also use thyroid replacement medicine, use it at least a couple of hours before and after using Lanthanum Carbonate. Please don't take Lanthanum Carbonate and thyroid medication all at once.

Avoid using an antacid within a couple of hours after or before you use Lanthanum Carbonate. This is because some antacids may make it more difficult for the body to soak up Lanthanum Carbonate.

If you need any kind of CT scan or X-ray using a dye that's injected into the veins, inform your doctor in advance that you're taking Lanthanum Carbonate.

Don't give anyone else Lanthanum Carbonate, even if they exhibit symptoms like your own. It may be dangerous for anyone to take Lanthanum Carbonate if it hasn't been prescribed by their doctor.