Lincomycin (Intravenous)



The lincomycin injection is prescribed for the treatment of bacterial infections and is sometimes also given for allergic reactions when patients are allergic to penicillin antibiotics. Is also used in the treatment of actinomycetes and certain species of plasmodium and mycoplasma.

This medication is an extremely strong antibiotic. It kills and prevents further growth of bacteria. However, the lincomycin injection is not effective for treatment of virus infections, flu, or colds.

This injection tends to have adverse side effects and high levels of toxicity, which is why it is rarely prescribed today. It is only prescribed for patients who have an allergy to penicillin, or when bacteria within the body has become resistant to other medications. Lincomycin has been linked to severe colitis which could end in death, which is why this medication must only be used when patients have a severe infection where a less toxic antibiotic is ineffective.

A severe type of diarrhea, CDAD (Clostridium difficile associated diarrhea) has been associated with this medication. These particular strains of Clostridium difficile can cause increased mortality and morbidity, due to the refractory nature of the infection to the antimicrobial therapy. Colectomy could be required. All patients who have diarrhea after the use of an antibacterial should be considered for having CDAD. Patients should have their medical history carefully examined as CDAD can take place over the course of two months after the medication is administered. If CDAD is confirmed or even just suspected, antibacterial use not intended for CDAD may need to be stopped. Supplementing with protein, managing electrolytes, and ensuring adequate fluid should take place as directed. Surgical evaluation may need to be implemented as clinically required.

This injection should only be given by your physician, a medically trained professional, or with their supervision in a medical facility.

This medication is available in solution for injection form and is currently manufactured under the US brand name Lincocin.

When choosing whether or not a medication is right for you, patients must always compare the potential risks of the drug against the possible benefits it may provide. This choice must be made along with your doctor. For lincomycin, consider the following aspects:

Individuals who have nonbacterial infections (like the majority of upper respiratory tract infections) should not take the lincomycin injection.

Patients with allergies should inform their physician if they have ever experienced allergic or unusual reactions to any medication, including this one. Also inform your physician if you have other kinds of allergies, such as to animals, preservatives, dyes, or foods. For products that are not prescription, be sure to read the ingredients on the package label carefully.

This medication should not be administered to children who are under one month old, as current research has not identified whether or not this injection is both safe and effective.

For geriatric patients, the lincomycin injection does not have any side effects that differ from the potential side effects for adults.

Either research has not yet been conducted on pregnant women or animals while on the lincomycin injection but animal research has demonstrated a negative effect, or animal studies demonstrated a negative effect and research for pregnant women has not been conducted.

Breastfeeding patients should compare the possible benefits against the risks that could take place prior to taking this medication while breastfeeding. Currently, there has not been any adequate research conducted to determine if there is a risk to the infant if the mother takes lincomycin while breastfeeding.

Conditions treated

  • Bacterial infections
  • Allergic reactions

Type of medicine

  • Antibiotic

Side Effects

In addition to the necessary benefits medications can provide, sometimes drugs can also cause side effects that are undesirable. While not every one of the following side effects will take place after taking lincomycin, they could require medical care if they do occur.

Consult with your physician or nurse right away if you experience any of the side effects below:

Lincomycin Side Effects ' Occurrence Rate Unknown (Medical Care Required)

  • Yellow skin or eyes
  • Weakness or tiredness (unusual)
  • Vision blurred
  • Ulcers, white spots, or sores on lips or in mouth
  • Tarry, black stools
  • Swelling or puffiness around tongue, lips, face, eyes, or near eyelids
  • Sweating
  • Swallowing difficulty
  • Stools that are like clay in color
  • Stomach or abdominal tenderness or pain
  • Sore throat
  • Skin paleness
  • Side or lower back pain
  • Severe pain, stomach, or abdominal cramps
  • Severe diarrhea (watery, sometimes even bloody)
  • Rash, itching, or hives
  • Quick heartbeat
  • Nausea
  • Muscle or joint pain
  • Loosening, peeling, or blistering of skin
  • Lightheadedness, faintness, or dizziness when suddenly standing from a sitting or lying position
  • Lesions of the skin (often red with a purple-colored middle)
  • Irritated, red eyes
  • Headache
  • Fever
  • Difficulty or pain when urinating
  • Diarrhea
  • Dark colored urine
  • Cough
  • Confusion
  • Chills
  • Chest tightness
  • Bruising or bleeding (unusual)
  • Breath odor (unpleasant)
  • Blood vomiting
  • Appetite loss

Certain side effects could also take place while on the lincomycin injection that may not require medical care. These particular side effects will likely diminish throughout the course of treatment as you become more adjusted to the medication. In addition, your doctor can inform you of additional methods of reducing or preventing certain side effects. Consult with your physician if the side effects below become troublesome, prolonged, or if you have concerns or questions regarding them.

Lincomycin Side Effects'Occurrence Rate Unknown (Medical Care Not Required)

  • Tongue soreness, swelling, or redness
  • Stomach or abdominal discomfort
  • Spinning sensation
  • Sensation of movement (constant) of surroundings or self
  • Loss of hearing
  • Hard lumps, redness, or pain at place of injection
  • Drowsiness or sleepiness (unusual)
  • Buzzing, bringing, or other types of noises that are unexplained within ears

Additional side effects not included above could also take place for certain patients after receiving the lincomycin injection. Consult with your medical care professional if you observe other side effects that are not included here.

Contact your physician with any questions regarding side effects of lincomycin. Side effect reports may also be reported to the FDA by calling 1-800-FDA-1088.


A medical care professional will administer this medication to the patient. It is given as an injection into an eye, vein, or muscle.


While some medications should not ever be used at the same time, in certain circumstances such medications can be used simultaneously despite the likelihood of interactions taking place. Under these circumstances, your physician may request the dose to be changed, or they may pursue other precautions to protect you as a patient. While receiving the lincomycin injections, it is essential that your doctor is aware if you are already taking medications on the list. These interactions were chosen due to the potential significance of the interaction with lincomycin. The list is not completely all-inclusive.

Taking lincomycin with the medications below is not typically suggested; however, certain cases may require the combination. If both drugs are prescribed at the same time, your physician may alter the dose or frequency for both or one of the medications.

Some medications should not be administered near mealtime or when having certain kinds of food as the likelihood of interactions taking place may be higher. The use of tobacco or alcohol with some medications can also trigger interactions to take place. Ask your doctor how tobacco, alcohol, and food will impact the lincomycin medication.

Other medical issues could impact the usefulness of this injection. Be sure to inform your physician of other medical issues you may have, specifically:

  • Liver disease (severe) take caution, increased side effects could take place due to slower extraction of the medication from the human body
  • Kidney disease (severe)
  • Diarrhea
  • Bowel or stomach disease (such as colitis), including history of' take caution, conditions could be made worse
  • Asthma (or history of)
  • Allergy (including history of)


It is highly essential that your physician regularly monitor the progress of the patient while having the lincomycin medication administered. This will give your physician a chance to see if the medication is working as it should, and it will give you a chance to decide if the medication is one that you want to continue receiving. Urine and blood tests could be requested to monitor for undesirable side effects. This medication should not be used in combination with Ery-Tab® (erythromycin).

Severe allergic reactions can take place for patients on the lincomycin injection. Anaphylaxis is one of the allergic reactions that can take place, and it can potentially be life threatening and require emergency medical care right away. Contact your physician immediately if you experience swelling of the mouth, face, or hands; difficulty swallowing; difficulty breathing; hoarseness; hives; itching; or rash after having a dose of lincomycin.

This medication could cause diarrhea to take place, and in certain circumstances symptoms can be severe. Diarrhea has been identified as a symptom of almost all antibacterial agents. This is because treatment from an antibacterial agent typically alters the usual colon flora, which leads to diarrhea taking place. This could take place for two whole months prior to or after stopping the injection. Diarrhea medications could prolong the diarrhea or may simply make it worse. Consult with your physician if you have any questions regarding this, or if mild symptoms become worse or prolonged.


As a healthcare professional must administer this medication to the patient, they will ensure that it is stored properly following all requirements the manufacturers of lincomycin have outlined.


The lincomycin injection is effective in the treatment of bacterial infections and is occasionally also prescribed for allergic reactions when patients have allergies to penicillin antibiotics.

Lincomycin is an antibiotic. It prevents and kills the growth of bacteria. However, the lincomycin injection is not successful for the treatment of virus infections, flu, or colds.

This injection should only be given by your physician or with their supervision.