Lorcaserin (Oral)

Lorcaserin is a prescription diet pill that acts to control the appetite, which is especially helpful in patients who need to lose weight for medical reasons such as diabetes, hypertension and high cholesterol.


Patients who are struggling with a medical problem because they are overweight or obese may be considered for treatment with prescription weight loss medication such as Lorcaserin, known as Belviq in the market. Lorcaserin directly affects the appetite control signals in the brain and help patients feel full with less food. Patients are often prescribed a nutritious diet as well as an exercise program to provide a well-rounded treatment therapy.

Lorcaserin does not directly treat any health conditions that have already resulted from the patient being obese such as diabetes, hypertension or heart disease. It is effective, however, in treating weight loss in patients who have these chronic conditions, making the patient healthier than they were and sometimes lessening the condition as the patient loses weight.

Lorcaserin has been developed for long term use in obese patients to provide appetite control. The active ingredients in the drug directly affect the receptors in the brain that make patients feel full, satisfied and satiated while eating, resulting in a reduced intake of food. Generally considered safe for most patients to take, as long as the other health guidelines of diet and exercise are adhered to, the majority of patients also experience successful weight loss when taking the medication.

Conditions Treated

  • Obesity (Index greater than 30 kilograms per square meter of body mass)

Type Of Medicine

  • Serotonin receptor agonist
  • Anti-obesity medication
  • Weight loss drug
  • Diet pill

Side Effects

Lorcaserin directly affects certain functions in the brain and, in doing so, may have adverse effects as well as the desired effects of the drug. If you have any of the following symptoms, get in touch with your physician right away:

  • Anxious demeanor
  • Pain in bladder
  • Urine is cloudy or shows signs of blood
  • Vision blurriness
  • Painful body aches
  • Chills
  • Loss of consciousness
  • Cold sweats
  • Confused demeanor
  • Pale, cool skin
  • Coughing
  • Depressed mood
  • Burning, difficult or painful urination
  • Dizzy, lightheaded or passing out
  • Difficulty breathing
  • Congested ears
  • Rapid heart rhythm
  • Elevated body temperature
  • Frequent urination
  • Headache
  • Feeling and increase in hunger
  • Vocal changes or loss
  • Pain in side or lower back
  • Runny nose, congestion or sneezing
  • Nausea
  • Nightmares
  • Ears pound
  • Seizures
  • Shaking limbs
  • Rapid or sluggish heart rhythm
  • Speech is slurred or different
  • Throat soreness
  • Tender, swollen breasts in males and females
  • Unexpected milk from breasts or increased
  • Fatigue
  • Muscle weakness
  • Swollen, bloated facial features, hands, arms, feet or legs
  • Decreased activity ability
  • Mouth dryness
  • Dry, flushed skin
  • Fruity smell on breath
  • Hunger has increased
  • Sensitivity to light
  • Thirst has increased
  • Urination has increased in frequency or amount
  • Painful joints
  • Red, itching, painful or swollen eyes
  • Losing consciousness
  • Gaining weight rapidly
  • Hives or rash on skin
  • Stomach ache
  • Increased sweat production
  • Glands are swollen
  • Feet or hands tingle
  • Difficulty breathing
  • Insomnia
  • Weight loss or gain that is unexplained
  • Vomiting
  • Increased tear production
  • Stool that is black or tar-like
  • Pain in chest
  • Coughing or hoarse voice
  • Skin paleness
  • Ulcerated white spots on mouth or lips
  • Bruising or bleeding that is unexpected
  • Agitated mood
  • Confused demeanor
  • Convulsions
  • Elevated body temperature
  • Increased sweat gland activity
  • Diarrhea
  • Little to no bladder control
  • Reflexes are hyperactive
  • Erection that is prolonged or painful
  • Clumsy, uncoordinated demeanor
  • Restless mood
  • Muscle stiffness to the extreme
  • Shivering
  • Uncontrolled excited reactions to normal thing
  • Shaking, trembling or twitching

Other side effects, while annoying, are not cause for alarm and typically alleviate themselves over time with use of the medication. It is still a good idea to get in touch with your physician about these symptoms, should you have them, in case there is a way to ease them right away:

  • Appetite has lessened
  • Constipation
  • Pain in back
  • Muscle aches or tenderness
  • Concentration is difficult
  • Eyes are dry
  • Spasms in muscles
  • Joint, bone or muscle pain
  • Skin rash
  • Insomnia
  • Stressed feeling
  • Toothache
  • Difficulty seeing

Seek emergency medical assistance should you experience an overdose of the medication, which includes symptoms such as:

  • Uncomfortable abdomen or stomach feeling
  • Strange sense of calm well-being
  • Delusions in sight, sound or feeling

Occasionally patients have unusual symptoms that aren't listed here; it is always best to report any change to your overall health or demeanor to your physician right away to protect your future health.


Read and understand the patient information leaflet that arrives with your prescription of Lorcaserin. If you have any questions, ask your doctor or pharmacist before you take the medication. Make absolutely certain you are aware of how this medication is supposed to affect your eating habits and any risks associated with taking the drug.

Take only the amount of the medication you are prescribed exactly as instructed and do not increase the size of the dose, the frequency you are to take it or the duration of your medication treatment. Your doctor will provide you with a calorie reduction diet plan and an exercise recommendation. Before you start any other diet or exercise plan than what you have been prescribed, consult with your doctor.

If you have not responded to this medication with a loss of weight within three months, your physician will most likely direct you to discontinue taking the medicine as it isn't working on your condition. Consult your physician on the duration of the medication regiment you are to take with Lorcaserin.

Adults who need the assistance of Lorcaserin to lose weight will typically be prescribed 10 milligram dosage amounts to be taken twice daily. Do not miss a dosage of the medication and if you accidentally do, skip it in favor of resuming your normal schedule. To maintain the safety of your health, do not double your dosage and risk an overdose situation.


Sudden or severe sensitivity symptoms that you have experienced with any medications in the past should be communicated to your doctor or nurse before beginning this medication. Include any reactions to animals, foods, perfumes, preservatives or dyes as well. Some of these ingredients may be found in the medication, so it is best to read the contents label and check with your health care professional if you have sensitivity to any substances.

Pediatric patients have not been studied to determine the safety or effectiveness that Lorcaserin would have in treating appetite control in the very young. Geriatric patients are assumed to be safe and able to take this medication unless they have age-related kidney diseases, requiring an adjustment to the dosage of the medication.

Women who are pregnant should not have weight loss goals in mind during their pregnancy and this medication has been known to cause fetal harm. Women who are pregnant are advised not to take this medication and, if you become pregnant while taking it, you should alert your physician to this fact as soon as possible. Practice reliable forms of birth control while on drug treatment with Lorcaserin.

Lorcaserin may or may not pass through breast milk and be ingested by breastfeeding infants. To maintain the health of your infant, it is not recommended that you continue breastfeeding if you are taking Lorcaserin. Discuss breastfeeding options with your physician while you are on this medication.

Certain medications can create dangerous health conditions when combined with Lorcaserin, either by exacerbating the health risks in taking the drug or by changing the effectiveness on your system. To be absolutely certain of your continued good health, alert your physician to any other medications that you take and include over-the-counter brands as well as vitamin and herbal supplements and holistic therapies.

Specifically, if you are taking the following medication, be aware that your physician will make another choice of diet drug other than Lorcaserin, as the two medications do not react well together:

  • Thioridazine

With regard to the drugs below, while it is not ideal for you to take them with your Lorcaserin medication, it is sometimes required for your health symptoms. Let you physician know if you take one of the following drugs so that any dosage adjustment can be determined:

  • Amitriptyline
  • Almotriptan
  • Brompheniramine
  • Amoxapine
  • Buspirone
  • Buprenorphine
  • Chlorpheniramine
  • Carbamazepine
  • Clomipramine
  • Citalopram
  • Cyclobenzaprine
  • Cocaine
  • Desvenlafaxine
  • Desipramine
  • Dolasetron
  • Dextromethorphan
  • Duloxetine
  • Doxepin
  • Escitalopram
  • Eletriptan
  • Fentanyl
  • Fenfluramine
  • Fluvoxamine
  • Fluoxetine
  • Furazolidone
  • Frovatriptan
  • Hydroxytryptophan
  • Granisetron
  • Iproniazid
  • Imipramine
  • Levomilnacipran
  • Isocarboxazid
  • Lithium
  • Linezolid
  • Methadone
  • Meperidine
  • Milnacipran
  • Methylene Blue
  • Naratriptan
  • Mirtazapine
  • Nortriptyline
  • Nefazodone
  • Palonosetron
  • Oxycodone
  • Pentazocine
  • Paroxetine
  • Procarbazine
  • Phenelzine
  • Rasagiline
  • Propoxyphene
  • Safinamide
  • Rizatriptan
  • Sertraline
  • Selegiline
  • St John's Wort
  • Sibutramine
  • Tramadol
  • Sumatriptan
  • Trazodone
  • Tranylcypromine
  • Venlafaxine
  • Tryptophan
  • Vortioxetine
  • Vilazodone
  • Zolmitriptan
  • Ziprasidone

You will be following a doctor prescribed health regimen that includes exercise and diet changes to improve your weight loss. Any interactions between certain foods and Lorcaserin will be disclosed to you by your physician. You should also discuss the consumption of alcoholic beverages and use of tobacco products with your physician in case there are recommendations with regard to each of these substances.

Certain medical issues may also cause the effectiveness of Lorcaserin on your appetite control to be diminished or even create a higher risk factor with regard to unwanted effects. You may even experience a worsening of your health symptoms with regard to your condition, so it is best to alert your physician of your medical history, especially if it includes:

  • Slow heart rhythm condition known as bradycardia
  • Congestive heart failure
  • Depression, MAD or other mental disorders
  • Diabetes
  • Blockage in the cardiovascular system
  • Heart valve problems
  • High blood prolactin levels
  • Low blood sugar levels
  • Hypertension
  • Liver disease
  • Kidney disease, end stage or severe
  • Penis abnormality including curvature or birth defects such as Peyronie's disease
  • Blood cancers such as Leukemia
  • Sickle-cell anemic conditions


Expect to visit your doctor for regular check-ups during your treatment with Lorcaserin to monitor the effectiveness of the drug on your weight loss and to determine if you are safe to continue taking the drug. You may be asked to give blood samples for testing with the results to be explained to you during this visit.

Use of Lorcaserin while pregnant may cause fetal harm. Discuss the risks of this medication with your doctor and make sure you are using a reliable form of birth control during your drug therapy treatment. If you think you've become pregnant while on this medication, let your doctor know right away.

Certain medications, when combined with Lorcaserin, can create serious health conditions like neuroleptic malignant syndrome or serotonin syndrome. Alert your doctor to the signs of these conditions such as confused mental state, elevated body temperature, restless demeanor, and rapid heart rhythm, spasms in muscles, difficulty walking, vomiting, diarrhea or nausea. Make sure your doctor is provided with a full list of your medications prior to taking Lorcaserin and include any non-prescription, holistic, herbal or vitamin supplements as well.

If you begin to rapidly gain weight or have swollen feet, lower legs or ankles while taking Lorcaserin accompanied by difficulty breathing, let your doctor know of these symptoms right away.

Patients have reported diminished alertness and difficulty thinking and making decisions while taking Lorcaserin, so before you operate a motor vehicle or use power tools or machinery, make sure you know your alertness level before you do to protect yourself and others from harm. If you have any concerns about the effects of the drug, discuss them with your doctor.

Make sure people close to you are aware you are taking this medication and are helping you be alert for any changes to your thought or behavior patterns such as extreme confusion, depressed mood, hallucinating, thoughts or tendencies toward suicide, and strange, over-excited reactions or nervous demeanor. Report these mood changes to your physician right away.

Diabetic patients will experience an improvement in their blood sugar levels as the result of the weight loss that comes with taking Lorcaserin, possibly creating a situation where the blood sugar levels are too low. Check your blood sugar on a more frequent basis while you are taking this medication and check with your physician if you notice any unusual blood sugar level changes.

Male patients who experience a painful or prolonged erection lasting over four hours should contact their physician right away, as this condition requires medical treatment immediately to prevent any long-term damage to your health. Discuss this risk with your physician prior to taking Lorcaserin.

Avoid other medications while you are taking Lorcaserin unless your doctor has specifically approved of them. This includes all health remedies such as vitamins, minerals and supplements as well as over-the-counter pain medications and treatments.


Keep your Lorcaserin dosage in the original packaging, stored at room temperature away from exposure to extreme cold, heat, moisture or light. Safely keep Lorcaserin out of sight and reach of children and pets. Dispose of any unused or out-dated medication according to local regulations or as instructed by your physician or pharmacist.


Lorcaserin is a weight loss prescription tablet that, along with diet and exercise, can assist patients in losing weight for their own health. Patients who are prescribed Lorcaserin are often suffering from obesity related health issues such as hypertension, diabetes, cardiac disease, high cholesterol and other ailments. While this medication does not treat these effects of obesity, it can cause the weight loss that will improve them as the patient progresses through treatment.

Lorcaserin works on neurotransmitter enzymes in the brain to make the patient feel satisfied with less food. Doctors will prescribe a weight loss program in addition to Lorcaserin that includes a low calorie, balanced diet plan as well as an exercise regimen. Typically patients should only take 12 weeks of Lorcaserin and, if they do not have success losing weight, they should discontinue taking the drug.

Safe for adult and geriatric patients, Lorcaserin should not be prescribed for the treatment of childhood obesity nor should it be used by pregnant women or women who are breastfeeding. Elderly patients with kidney related diseases should have their dose cautiously adjusted to accommodate their health condition.

Typical symptoms reported by some patients include muscle aches, constipation and joint or bone pain and some mood changes. Serious effects on health should be reported if they are severe or prolonged or include any suicidal behaviors or thoughts. Overdose symptoms include stomach pain and delusional thinking or a false sense of safety. Alert your health professional staff to any changes in your health or mood symptoms during your treatment.

While not a magic bullet for weight loss, Lorcaserin has been proven over many years to be effective and safe for most patients to begin a diet plan that helps them lose weight. By assisting the brain in being satisfied with less food, Lorcaserin can be a big contribution to weight loss success.