Luliconazole (Topical)

Luliconazole is an antifungal medicine used by adults to treat fungal infections; it’s a topical medication that helps to alleviate the symptoms caused by ringworms, jock itch, and athlete’s foot.


Luliconazole is applied to the skin to treat fungal infections; the product must be appropriately used as instructed by a healthcare professional. The medication is available in cream form and should be applied to the affected area every day as instructed. Luliconazole is only meant to be used on the skin, so do not apply it on the eyes, mouth, or nose. It's always recommended to complete the dosage given by your doctor, even when you start feeling better; if you fail to do so, the symptoms might reappear.

The dosage given depends on the ailment being treated and other underlying conditions that the patient may have, such as allergic reactions to the components of luliconazole. Before you start using this cream, it's important to tell your doctor if you're allergic to luliconazole or other prescription drugs that may have similar components. People who are allergic to certain foods, animals, or herbal products should consult a healthcare provider before using this medicine. It's not recommended to start, change (dosage), or stop taking any other over-the-counter medication when using this drug without confirming with your doctor first.

Inform all your healthcare providers including dentists, pharmacists, nurses, and doctors that you are using this drug. Also, pregnant women and those planning to conceive must also discuss with their doctors to ensure that they are fully aware of all risks and benefits. The same also applies in case you are breastfeeding.

For the best results, ensure that you take the dosage as instructed. If you miss a dose, apply the cream as soon as you remember; however, do not put on a double dose to cover the missed one. Skip the dose you have missed if it's already time for the other dose to avoid overdosing on the drug.

Conditions Treated

Type Of Medicine

  • Antifungal

Side Effects

Along with the effects needed to treat fungal infections, luliconazole also causes several side effects. Nevertheless, not all these unpleasant effects may occur, and some may be more or less severe. Seek medical attention if the following symptoms start to show, especially at places where the cream is applied:

  • Redness
  • Stinging
  • Signs of irritation
  • Dry skin
  • Blisters on skin
  • Crusting
  • Peeling of the skin
  • Scaling
  • Severe redness
  • Soreness

Some side effects are rare, but they may be severe still. Check with your doctor in case you exhibit the following symptoms, especially if they become chronic:

  • Eczema
  • Burning
  • Stinging
  • Itching

Other side effects of this medication may not be listed here. If you experience any other unpleasant effects of the drug, it's advisable to tell your doctor. You should also report to the FDA so that they can include the symptoms in their data.


The dosage prescribed depends on the condition being treated. To treat athlete's foot, you need to apply the medication to the affected area and the skin close to it. The dose should be administered once every day, and it should be used for not more than two weeks.

When the medicine is used to treat ringworms, patients are required to apply the cream on the affected areas once per day for not more than one week.

For jock itch, on the other hand, the medicine is applied to the affected areas once per day for not more than one week. The dose works best when the cream is applied at the same times of the day.

Luliconazole should only be used for application on the skin; it should not be swallowed. If someone swallows this medicine, call the local poison control or take the victim to the hospital immediately. Symptoms of overdosing include difficulty in breathing and unconsciousness.

Do not share your dosage with other people, even if they exhibit similar symptoms. The medication is prescribed for a particular patient's current condition only. Avoid using the cream at a later date for a different infection, unless you have been directed by a healthcare professional to do so. Do not alter dosages as this can cause the occurrence of severe side effects.


Luliconazole may interact with other over-the-counter medication, supplements and herbal products to cause severe side effects. However, the interaction may be different for every individual, so it's recommended to consult your doctor if you are using other types of medicine, especially skin creams. Skin whitening creams may cause cancer or liver damages when used together with luliconazole.

Some medical procedures performed on your skin such as laser treatments or tattoo removals may interact with the medication to cause adverse effects. Always inform your doctor in case you have had any procedure done on your skin in the recent past.

On the other hand, it's unlikely that other medication taken orally or intravenously may interact with luliconazole.


Some precautions have to be observed when using luliconazole. Although in rare cases, liver damage has been reported by people with other underlying severe ailments. People who use skin whitening creams are also at high risk of damaging their liver. Injury to the liver may be fatal at times so seek medical attention if you develop the following signs:

  • Yellow skin or eyes
  • Abdominal pain
  • Dark urine
  • Raised liver enzymes

When applying this medicine, be careful to avoid getting it into the eyes, mouth, nose, or vagina. If this does happen, rinse the medication out by using plenty of cool water.

Ensure that your skin is completely dry after taking a bath because fungal infections are more prevalent in moist conditions. Avoid walking around barefoot as well. To prevent getting infected again, it's advisable to wear clean clothes, preferably made from cotton, but not synthetic material. Inform your healthcare provider immediately if you develop blisters or sores that do not heal after a few days. Consult your doctor if the infections come back (or fail to improve) after you have finished the prescribed dose.

Patients who are using luliconazole for treating jock itch should not wear tight-fitting underwear, especially garments made from nylon, rayon, or other synthetic materials. Instead, opt for cotton underwear that is loose-fitting. Ensure that you dry the groin area thoroughly after bathing.

When using luliconazole for the treatment of athlete's foot, make sure that your feet are entirely dried (particularly between your toes) after you take a bath. Avoid wearing socks that are made from synthetic fabric such as nylon. Also, do not wear wool socks, it's best to wear clean socks made from cotton. If your feet are too sweaty, change the socks every day; you can also try to put on sandals or shoes that have adequate ventilation.

To prevent any undesirable side effects, always use the medication as directed by your doctor.

For best result, observe the following tips:

  • This medicine should only be used on the skin; it may burn your eyes, nose, and mouth.
  • Wash your hands thoroughly with plenty of water before and after applying the medicine. However, do not wash your hands if you have applied the medication to them.
  • Before you apply the cream, clean the affected area and use a towel to dry it.
  • Take a thin layer of the medicine and apply it evenly on the affected area. Rub it in gently until it is absorbed into the skin.
  • Do not skip doses so that you can get the desired results.
  • Use the medicine correctly and as instructed by your doctor; do not alter doses, even when you feel that your condition is improving.


Here are essential guidelines for handling and storing luliconazole properly:

  • Store the medication in its original container and ensure that it is closed at all times.
  • Keep the medicine in a safe place that is out of reach for kids and pets.
  • Store the medicine at room temperature.
  • You can keep the medication in a refrigerator but not in the freezer.
  • Store the medicine away from moisture, light, and heat; do not keep it inside your bathroom cabinets.
  • After using the medication, ensure that you close the caps tightly. If you have children at home, choose child-proof caps.
  • After applying the required daily dose put the medicine away until the next dose. Keeping the medication close by may give you the urge to alter the dosage.
  • Dispose of any unneeded or expired medication. Any unused medication should be discarded after two weeks.

Consult a waste disposal company or your healthcare provider to learn the appropriate ways of getting rid of unneeded medication.


Luliconazole is a topical medication that is used to treat fungal infections in adults. The medicine is not recommended for people under 18 years of age. Apart from managing ringworms, athlete's foot, and jock itch, this cream may also be used for treating other conditions. However, do not use this medication for any other disease or an extended period without consulting a healthcare professional.

It's important to use the medicine as directed. Also, tell your doctor about all other over-the-counter drugs, herbal products, and supplements that you use.