Menthol and Zinc Oxide (Topical)

Menthol and Zinc Oxide is an over-the-counter topical treatment for skin irritations, such as chaffing, diaper rash, or minor cuts and burns.


Menthol and Zinc Oxide is used topically to alleviate a variety of skin-related discomforts including itching, rashes, and more. The skin irritations that are treatable with Menthol and Zinc Oxide may be caused by bodily fluids, such as urine, sweat, or stools as well as:

  • Feeding tube leaks
  • Drains from wounds
  • Minor burns
  • Cuts and scrapes
  • Excessive scratching

Menthol and Zinc Oxide are the main active ingredients of popular brands like:

  • Caladrox
  • Calmodrox
  • Calmoseptine
  • Gold Bond Medicated Body Powder
  • Gold Star Medicated
  • Lantiseptic Multi-Purpose
  • Medicated Body
  • Remedy Calazime
  • Risamine

These are available without a prescription and sold over the counter by several retailers. Moreover, Menthol and Zinc Oxide may be purchases as a powder, ointment, or paste.

Main applications

The primary reasons for using Menthol and Zinc Oxide are generally for:

  • The alleviation of skin irritations, such as rashes and chapped skin
  • The prevention of wetness or moisture settling on the skin
  • The treatment of diaper rash, which is common in newborns and babies
  • Providing soothing relief after sustaining a minor cut, burn, or scrape

In essence, the medication absorbs excess moisture and provides calming relief for itching, burning, and general discomforts associated with irritated skin. Menthol and Zinc Oxide additionally form a barrier to protect sensitive skin from wetness.

The active ingredients in this blend each serve unique purposes. For example:

  • Zinc Oxide ' protects the skin from excess moisture
  • Menthol 's categorized as an analgesic (external only) and first aid antiseptic.

Conditions Treated?

  • Diaper Rash, Chapped Skin, Minor Burns, Cuts, Scrapes, Sunburn

Type Of Medicine?

  • First Aid Antiseptic, External Analgesic

Side Effects

Limited side effects have been found for Menthol and Zinc Oxide.

In rare cases and for individuals with a history of allergies, this topical treatment may trigger anaphylaxis shock. Pay attention to the warning signs, including new rashes, swelling, hives, welts, difficulty breathing, and pain in the chest. If you develop these symptoms, call 911 immediately. Anaphylaxis shock is a serious and potentially fatal condition that requires immediate medical intervention.

Note: Individuals who have known hypersensitivities to Menthol and Zinc Oxide should not take this medicine. Instead, ask a pharmacist or healthcare provider about alternative treatments. In addition, different brands of Menthol and Zinc Oxide may contain numerous inactive ingredients. To be safe, read through the list of both active and inactive ingredients to pinpoint any known allergies.


The average dose amounts for Menthol and Zinc Oxide are largely based on the patient's age, as well as the brand and the type of skin irritation being treated.

However, Menthol and Zinc Oxide is generally administered 2-4 times daily. For ointments or pastes, a penny-sized squeeze is suggested ' to be spread into a thin layer at the affected skin area.

Proper use

For best results, read the full instructions that are printed on the label.

The best practices for use of this topical medication include:

  • Start with clean hands'to reduce the risk of contracting an infection, scrub your hands thoroughly with soap for up to two minutes, then rinse under warm running water. Air dry your hands or use a clean towel to soak up excess water. Remember, irritated skin is more susceptible to bacteria and viruses. It is therefore important to follow this first step before applying the ointment, powder, or paste.
  • Follow the instructions ' the methods of application vary depending on whether you're using an ointment, powder, or paste of Menthol and Zinc Oxide. As a result, read the directions carefully, especially if this treatment is used on a baby's sensitive skin.

Menthol and Zinc Oxide Ointment for Diaper Rash

Not only does Menthol and Zinc Oxide treat diaper rash, it also prevents it, too.

When using Menthol and Zinc Oxide ointments for diaper rash, the instructions for use are applying a very thin layer of the ointment:

  • Every time you change baby's diaper
  • Right before sleep or naptime
  • When baby is going to the daycare
  • When the diaper stays wet for a long time
  • After swimming

Note: Do not exceed the recommend dosage or the number of times per day listed on the label.


No contraindications have been found when Menthol and Zinc Oxide is used in conjunction with other medicines. However, it's still a good idea to discuss with your doctor a complete list of all medications being taken before starting this treatment.


Before administering treatment with Menthol and Zinc Oxide, read the instructions on the label in detail. Some of the main precautions include:

Topical use only

Menthol and Zinc Oxide is indicated for topical use only. In other words, the ointment, powder or paste should only be applied to the skin's surface.

In the event of an accidental overdose, contact 911 immediately. The American Association of Poison Control Centers can also be reached by calling 1-800-222-2222.

If the medicine gets into the eyes, rinse it out with warm running water and seek medical help right away.

Exclusions for Use

Though this medicine is indicated for skin irritations, Menthol and Zinc Oxide is not suitable for treating deep wounds. However, if the surrounding skin is affected, your healthcare provider or pharmacist may recommend carefully applying the treatment to the exterior of the wound only.

In addition to deep wounds, Menthol and Zinc Oxide should never be applied to:

  • Animal bites
  • Severe burns
  • Deep cuts
  • Fungal infections

Worsening symptoms

If the skin irritation shows no signs of improvement after a week of treatment with Menthol and Zinc Oxide, consult your healthcare provider.


Some patients may develop an allergic reaction to this medicine. Be sure to tell your healthcare provider if you or your child have any hypersensitivities to menthol or zinc oxide. Also, note any past adverse reactions to any foods, dyes, preservatives, or other drugs.

Some of the main warning signs of an allergic reaction include:

  • Hives
  • Swelling
  • Welts
  • Chest tightness
  • Difficulty breathing
  • Wheezing

If any of these symptoms occur while using Menthol and Zinc Oxide, discontinue use and call 911 immediately.

Medical history

To help keep you safe, inform your doctor if you are currently using any medicines, as certain drugs may interact negatively with Menthol and Zinc Oxide. This includes any over-the-counter medicines such as herbal supplements or vitamins.

Also, discuss any underlying conditions you have with your healthcare provider, which may get worse with Menthol and Zinc Oxide use. Though this is an over-the-counter medicine, it is still wise to check in with your primary care doctor before starting any new treatments.


Do not use Menthol and Zinc Oxide treatments if you are pregnant or plan to be, without first consulting your healthcare provider. Similarly, if you are nursing, check with your doctor first to verify the safety of using this medicine.


Keep the medicine in the original container at a room temperature of 20- 25°C (68- 77°F).

Do not store Menthol and Zinc Oxide pastes, ointments, or powders in direct sunlight, moisture, heat, or in a freezer.

Additionally, remember to always keep this medicine out of the reach of children and pets. Always check the expiration date on printed on the bottle, tube, or container to make sure the'œuse by date'has not expired.


Menthol and Zinc Oxide is a very common over-the-counter treatment for skin irritations caused by excess moisture. Parents of newborns and infants, for example, may be familiar with diaper rash, because oftentimes, disposable diapers trap moisture and heat.

To treat, healthcare providers generally prescribe over-the-counter Menthol and Zinc Oxide.

Though the name 'œMenthol and Zinc Oxide'may not be recognizable at first glance, readers may know the brand names of this medicine, such as Gold Bond Medicated Body Powder, Gold Star, or Risamine, for example.

Some of the main applications for use include diaper rash, itching, and minor cuts, scrapes, and burns. Menthol and Zinc Oxide both treats and prevents skin irritations, particularly in infants using disposable diapers or adults who sweat excessively.

There are some exclusions for use, including for deep wounds, animal binds, and fungal infections. In these events other treatments are required.

Menthol and Zinc Oxide should never be placed in one's eyes. mouth, or nose. It is indicated for topical use only. In the event this medicine is accidentally swallowed' or if it gets into the eyes or nose, contact 911 immediately. To prevent misuse, keep out of the reach of young children and pets.

The best practices for using this medicine include thoroughly washing the hands before each use, and applying a thin layer of the ointment, paste, or powder to the affected skin area only. This should be done generally 2-4 times daily, or as suggested by your healthcare provider.