Methocarbamol (Oral)


Methocarbamol is a central nervous system suppressant with a sedative. It is used in the treatment of acute pain caused by certain conditions of the bone and muscle. It is used in the treatment of acute pains but is not a replacement for rest and other treatments to improve pain. This medication is usually prescribed along with physical therapy, exercises and rest that will help to improve the problem.

This medication is only available when prescribed and is taken as a Robaxin or Robaxin-750 tablet.

Condition treated

  • Acute bone pain
  • Acute muscle pain

Type Of Medicine

  • Central nervous system suppressant
  • Sedative

Side Effects

In addition to the required effects of Methocarbamol, other unwanted effects can also occur. These side effects may require you to seek medical attention or may be milder and will abate over time.

The following side effects should be shared with your doctor immediately that they begin to occur:

Frequency of incidence not known:

  • Yellow eyes or skin
  • Wheezing
  • Vomiting of blood
  • Unusual tiredness or weakness
  • Unusual bleeding or bruising
  • Unpleasant breath odor
  • Total body jerking
  • Tightness in chest
  • Swollen glands
  • Sores, ulcers, or white spots on lips or in mouth
  • Sore throat
  • Slow or irregular heartbeat
  • Sleepiness
  • Skin rash
  • Shortness of breath
  • Relaxed and calm
  • Redness of the face, neck, arms, and occasionally, upper chest
  • Redness and soreness of eyes
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Problems with memory
  • Painful or difficult urination
  • Pain, tenderness, or swelling of foot or leg
  • Numbness or tingling of face, hands, or feet
  • Nausea
  • Loss of memory
  • Loss of consciousness
  • Loss of bladder control
  • Loss of appetite
  • Lightheadedness, dizziness, or fainting
  • Large swelling with a hive-like appearance on the:
  •  tongue
  • throat
  •  sex organs
  •  lips
  •  legs
  • hands
  •  feet
  • face
  •  eyelids
  • Joint or muscle pain
  • Itching
  • Hives
  • Headache
  • Fever
  • Feeling of warmth
  • Fast heartbeat
  • Dizziness
  • Difficulty swallowing
  • Diarrhea
  • Dark urine
  • Cough
  • Clay-colored stools
  • Chills
  • Chest pain or discomfort
  • Changes in skin color
  • Black, tarry stools
  • Abdominal or stomach pain

It is also possible to overdose on this medication. If you believe that you or anyone else has taken an overdose of this medication then you should contact the emergency services for treatment. Symptoms of overdose include the following:

  • Sweating
  • Shaking or jerking of one area or side of the body

Other side effects can also occur that do not require that you seek medical attention. These side effects are usually milder and will usually abate as your body gets used to the medication. If these side effects are ongoing or become bothersome, however, then you should inform your healthcare professional:

Frequency of incidence not known:

  • Uncontrolled eye movements
  • Unable to sleep
  • Trouble sleeping
  • Stomach discomfort, upset, or pain
  • Sleeplessness
  • Sensation of spinning
  • Seeing double
  • Mood or mental changes
  • Indigestion
  • Heartburn
  • Feeling of constant movement of self or surroundings
  • Drowsiness
  • Double vision
  • Belching
  • Acid or sour stomach

Methocarbamol can also cause other side effects that have not been listed herein to occur. If you experience any other side effects then you should inform your doctor and seek advice. If you believe your health to be at immediate risk, however, then you should always seek emergency care.


The dose of this medication given will differ between each patient. You must follow the dosing information given to you by your doctor only and should not ever take more nor take it more frequently than ordered.

The following information is based only on averages and should serve only as a guideline. These dosages do not take account of your personal condition and should not be used to change dose:

Adults should begin treatment with 500-1500mg taken four times daily. The doctor may increase this dose until the desired effect is achieved.

The use of this medication in children is not recommended and must be determined by the doctor where it is used.

If you miss a dose of this medication, then you should take it as soon as you are able to. You should not ever take a double dose of this medication. If you are close to your next dose being due then skip the missed dose entirely and return to your normal schedule.


Certain medications should not be used together. When drugs are used together they can interact with the body and this can cause severe medical problems to occur. To avoid drug interactions occurring you must inform your doctor of all medications that you are taking before you begin treatment with Methocarbamol. This includes all prescribed treatments and over the counter medications that you may be using. For Methocarbamol it is especially important that you inform your doctor if you are using any of the following:

The use of Methocarbamol with the following medications is not normally recommended. In some cases, you may be treated with both but your doctor may make changes to the dose taken and the frequency of use to prevent serious interactions from occurring:

  • Zolpidem
  • Triazolam
  • Tramadol
  • Thiopental
  • Temazepam
  • Tapentadol
  • Sufentanil
  • Sodium Oxybate
  • Secobarbital
  • Remifentanil
  • Quazepam
  • Propoxyphene
  • Primidone
  • Prazepam
  • Phenobarbital
  • Periciazine
  • Pentobarbital
  • Pentazocine
  • Oxymorphone
  • Oxycodone
  • Oxazepam
  • Nitrazepam
  • Morphine Sulfate Liposome
  • Morphine
  • Midazolam
  • Methohexital
  • Methocarbamol
  • Methadone
  • Metaxalone
  • Meprobamate
  • Mephobarbital
  • Mephenesin
  • Meperidine
  • Medazepam
  • Lormetazepam
  • Lorazepam
  • Levorphanol
  • Ketazolam
  • Hydromorphone
  • Hydrocodone
  • Halazepam
  • Flurazepam
  • Flunitrazepam
  • Flibanserin
  • Fentanyl
  • Ethchlorvynol
  • Estazolam
  • Doxylamine
  • Dihydrocodeine
  • Diazepam
  • Dantrolene
  • Codeine
  • Clorazepate
  • Clonazepam
  • Clobazam
  • Chlorzoxazone
  • Chlordiazepoxide
  • Chloral Hydrate
  • Carisoprodol
  • Butorphanol
  • Butalbital
  • Butabarbital
  • Buprenorphine
  • Bromazepam
  • Aprobarbital
  • Anileridine
  • Amobarbital
  • Alprazolam
  • Alfentanil

Other medications may also interact with Methocarbamol. This list has been selected for severity only and may not be all-inclusive. You should inform your doctor of every substance you are taking.

Other medical problems from which you suffer can also affect the use of this medication. You should inform your doctor of all conditions you have and this is especially important in the following cases

Methocarbamol use could also be affected by other conditions not listed. Ensure your doctor has your full medical history to consult before treatment commences.


Before you begin treatment with Methocarbamol it is important that you understand the risks of use and have weighed them against the benefits of use. You should decide to take this treatment with your doctor having ensured that all of the following has been considered:

Allergies ' You should inform your doctor if you have ever reacted badly to any other medication in the past. Allergies to medication and any other allergies could sometimes prohibit the use of Methocarbamol.

Pediatric' The safety and efficiency of use below the age of 16 has not been established for this medication. Discuss with your doctor before use.

Geriatric ' The studies performed to date have shown no limitation to the use in elderly patients. Elderly patients are more likely to have conditions of the liver that can impact on use, however.

Pregnancy ' There is a risk to the use of this medication when pregnant. You must inform your doctor if you are pregnant. Inform your doctor if you believe you have become pregnant during use of this medication.

Breastfeeding' There is only a minimal risk to the use of this treatment while breastfeeding. Discuss the risks with your doctor before use.

It is important that your doctor checks on your progress while you are receiving this treatment. The doctor will check that it is working properly and will also examine you for unwanted side effects. You must be honest about your condition with the doctor to get the best possible treatment.

This medication is a suppressant of the central nervous system and will intensify the effects of other suppressants. Some suppressants are common in everyday life and these need to be avoided during use of Methocarbamol. The most common of these is alcohol which must be avoided during treatment. Other suppressants that you will need to avoid include:

  • Antihistamines
  • Sedatives
  • Tranquilizers
  • Anesthetics
  • Narcotics
  • Barbituates
  • Asthma treatments

The use of this medication may make you drowsy, dizzy and/or less alert. When taking this medication it is important to ensure that you are fit before you carry out tasks that may put you or others at risk. Remember that it is your legal responsibility to ensure you are fit to carry out tasks including driving and operating machinery. Do not do so unless you are fully alert both physically and mentally.

Your urine may change color with the use of this treatment. You must inform any medical professional that you are taking this treatment before you undergo any other treatment or procedure. You should not take any other medication with Methocarbamol unless it has been expressly approved by the prescribing doctor.


You may store this medication at room temperature. You must keep it away from heat, direct light and moisture, however. Always store this medication well out of the reach of children. Dispose of any unwanted or unneeded medication properly as directed to by your doctor and ensure it remains out of reach of children and pets throughout.


Methocarbamol is a suppressant of the central nervous system and sedative that is used to treat acute pain of the muscles or bones. This medication is prescribed as an aid to recovery and is not a replacement for proper rest, exercise, physical therapy and other treatments that may be used to fix your health problem.

Patients taking this medication must use it exactly as prescribed and should not ever take an increased dose of the medication. To do so will pose a serious risk to health. Patients should also follow other advice from the doctor about steps to follow to recover thoroughly.

You should not drink alcohol while you are being treated with this medication. To do so will increase the effects of the alcohol and the medication and will put you at serious risk.

There are risks to the use of this medication when you are pregnant. You should inform your doctor before you begin use if you are pregnant and should avoid becoming pregnant during use.

You must inform all healthcare professionals that you are taking this treatment before undergoing any other treatment or procedure. You should not take any other medication with Methocarbamol unless you have been directed to by your doctor.

This medication may cause your urine to change color.