Minocycline (Injection)

Minocycline injections are used to treat any bacterial infections in different areas of the body and it can also be used in the treatment of severe acne or intestinal amebiasis.

Overview

Minocycline injections are used to treat any bacterial infections in different areas of the body. It can also be used in the treatment of severe acne or intestinal amebiasis.

It is also used in the treatment of infections in patients who cannot receive any penicillin antibiotics.

Minocycline is used in the treatment of many differing bacterial infections, including gonorrhea, urinary tract infections (UTIs), skin infections, respiratory infections, tick fever, severe acne, chlamydia, amongst others.

Minocycline belongs in the class of medications known as tetracycline antibiotics. It works by killing off the bacteria or by preventing the growth of bacteria. This medication will not work in the treatment of colds, flu, or any other virus infections.

This medication is to be administered only by or under the supervision of your health care provider.

This product is available in the following dose forms:

  • Powdered for Solution

Condition(s) treated

  • Bacterial infections

Type of medication

Tetracycline antibiotics

Side Effects

Although medication usually will help fight the issues you are facing, it may cause some unwanted or unexpected side effects.

You may not experience all of the following side effects, but if any do occur you may need to seek medical attention.

Contact your health care provider immediately if any of the following occur:

Incidence unknown

  • Trouble breathing
  • Bloody or cloudy urine
  • Diarrhea, watery and severe, which could also contain blood
  • Fever
  • Dark urine
  • Abdominal or stomach cramps or tenderness
  • Blistering, peeling, or loosening of the skin
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Sore throat
  • Nausea or vomiting
  • Scaly skin
  • Cough
  • Greatly decreased urination frequency or a great decrease in the amounts of urine passed
  • Eye pain
  • Cracks in the skin
  • Bloating
  • Unusual tiredness or weakness
  • Light-colored stools
  • Hives, itching, or rash
  • Pain
  • Severe stomach pain
  • Unusual weight loss
  • Increased thirst
  • Blurred or double vision
  • Red, swollen skin
  • Yellow eyes and skin
  • Upper right abdominal or stomach pain
  • Joint or muscular pains
  • Ulcers, sores, or white spots inside the mouth or on the lips
  • Red, irritated eyes
  • Dizziness
  • Difficulties with swallowing
  • A severe headache
  • Hive swellings on the eyelids, face, lips, throat, tongue, hands, feet, legs or genitals
  • Angry, red skin lesions. These are often seen with a purple colored center
  • Faster than usual heartbeat
  • Tightness in the chest
  • A feeling of losing the heat from the patients body
  • Swelling in the feet or the lower legs
  • Chills
  • Seizures
  • General tiredness and weakness

There are some side effects which may occur that usually will not need medical attention. These side effects mostly disappear during treatment, which is a normal side effect of your body adjusting to the medication. Also, your health care provider may be able to tell you about other ways to prevent or help to reduce some of these side effects.

Be sure to check with your health care provider if any of the following, more common side effects become annoying or if you have any further questions about them:

Incidence unknown
  • Stomach discomfort or upset
  • Belching
  • Difficulty with moving
  • Pain or redness at the injection site
  • Discoloration of the nail, tooth, or gum
  • Indigestion
  • Acid or sour stomach
  • Difficulty with swallowing
  • Heartburn
  • Hair loss or thinning of the hair
  • Loss of appetite
  • Muscle pain or stiffness
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • Weight loss
  • White, thick, or curd-like vaginal discharge
  • Hearing loss
  • Redness, swelling, or soreness of tongue

There are, of course, other side effects which are not listed that may also occur in some patients. If you notice any other effects, contact your healthcare provider for further information.

Dosage

A health care nurse or another specially trained health care professional will administer this medication to you or your child at a hospital. This medication is g administered by a needle placed directly into a vein, usually in your arm.

Interactions

Although there are certain medicines which should not be used together at all, there are other cases in which two different medicines can be used together even if an interaction were to occur. In these cases, the doctor may want to alter the dose, or impose other precautions if necessary. If you are prescribed this medication by another doctor or health care provider, it is especially important that they know if you are actively taking any of the medicines in the list below. The following list of interactions have been noted on the basis of their potential significance, but these medications are not necessarily all-inclusive.

It is advised that using this medicine with any of the following medicines is usually not recommended but could be required in some cases. If both medications are prescribed at the same time, your doctor may change the dosage or how often you have to use one or both of these medicines.

  • Acitretin
  • Bacampicillin
  • Temocillin
  • Penicillin G Procaine
  • Penicillin V
  • Nafcillin
  • Ampicillin
  • Atazanavir
  • Isotretinoin
  • Etretinate
  • Penicillin G Benzathine
  • Cholera Vaccine, Live
  • Bexarotene
  • Dicloxacillin
  • Methoxyflurane
  • Amoxicillin
  • Tretinoin
  • Pivampicillin
  • Digoxin
  • Methicillin
  • Oxacillin
  • Piperacillin
  • Penicillin G
  • Sultamicillin
  • Cloxacillin

If you are using this medicine with any of the following listed medicines you may experience an increased risk of certain side effects but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Vitamin A
  • Iron

Other Interactions

Certain medications should not be used when eating certain types of food since interactions can occur. The use of alcohol or tobacco with certain medications can also cause interactions to occur. You should consult with your health care provider regarding the use of this medication with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Diarrhea or
  • Kidney disease or
  • Increased feeling of pressure inside the head or
  • Liver disease'This medication should be used with caution as it can make this condition worse.
  • Warnings

Allergies

Tell your health care provider if you have experienced any abnormal or allergenic reactions to other previous medications. Also tell your health care professional if you have any allergies; to foods, preservatives, dyes or any animals.

Pediatric

Minocycline injections can in some cases cause permanent discoloration of the teeth and a slowing down in the growth of the child's bones. This medication should not be administered to children younger than eight years old, unless specifically directed to by the child's health care provider.

Geriatric

Elderly patients are much more likely to have age-related kidney, heart or liver issues, which could require more caution used and adjustments made in the dosage for all elderly patients receiving the minocycline injection.

Pregnancy

Studies conducted in pregnant women have positively demonstrated that there is a risk to the fetus. However, there may be benefits of the treatment in life threatening situations or if there is presence of a serious disease that can outweigh the potential risk.

Breastfeeding

Studies have suggested that this medication can alter milk production or the milks composition. If an alternative to this medication cannot be prescribed, you should monitor your child for any side effects and for adequate milk intake.

Your health care provider will monitor your or your child's progress very closely while you are receiving this medication. This will allow the health care provider to check if the medication is working the correct way and to decide whether you or your child should continue receiving it. It may be that blood and urine tests are needed to test for unwanted effects.

While using this medication during pregnancy can harm the unborn baby, the medication can also cause birth defects if the father is administered it when his sexual partner falls pregnant. If a pregnancy does occur while you are taking this medication, tell your health care provider immediately.

Birth control medication may also not work efficiently while you are taking minocycline. To prevent a pregnancy it is advised to use an additional form of birth control or contraception method. Other contraception includes: a diaphragm condoms, contraceptive gels or foam.

This medication can darken the color of your skin, eyes, nails, gums, teeth or scar tissue. Speak to your health care provider if you or your child have any further concerns.

Contact your health care provider immediately if you experience any of the following symptoms of autoimmune syndrome: fever, joint pain, rashes or unusual tiredness.

Minocycline can cause your skin to become much more sensitive to direct sunlight than it usually would be. Exposure to direct sunlight, even for short periods of time, could cause a rash, redness, severe sunburn, itching or other discoloration of the skin.

Due to this, it is advised when you use this medication:

  • Avoid direct sunlight, most notably during the hours of 10:00 a.m. to 3:00 p.m where possible.
  • Wear long, protective clothing, including a hat and sunglasses.
  • Apply sunblock with a minimum sun protection factor (SPF) number of 15.
  • Apply a sunblock lip balm with a minimum sun protection factor (SPF) number of 15.
  • Do not use sun lamps, tanning beds or booths.

If you experience a severe reaction due to the sun, seek advice from your health care provider.

This medication can cause some patients to experience dizziness or feelings of lightheadedness. Be sure you are aware of how you react to this medication before you attempt to drive, use machinery or do any other activity that could be classed as dangerous to avoid injury.

Minocycline can cause diarrhea and in some cases this can be quite severe. It can even occur upwards of 2 months or more after you stop receiving this medication. Do not take any medication that will treat the diarrhea without consulting with your health care provider. The use of diarrhea medications can in some cases make the diarrhea worse or last longer than it would without treatment. If you or your child have any issues with mild diarrhea that is ongoing or begins to get worse, consult with your health care provider.

This medication can cause increased pressure in the head which may lead to permanent vision loss. Speak to your health care provider immediately in the case of you or your child experiencing severe headaches, blurry vision or experience any changes in vision.

Speak to your health care provider urgently if your child or you have any pains or begin to experience tenderness to the upper part of the stomach, pale stools, dark urine, vomiting or nausea, lost appetite or any yellowing to the eyes or areas of skin. These symptoms suggest a serious liver issue.

Storage

This medication should be stored at a health care facility, however if you are to store this at home, speak to your health care professional regarding the best way to do this.

Summary

Minocycline injections are used to treat any bacterial infections in different areas of the body. It can also be used in the treatment of severe acne or intestinal amebiasis.

It is also used in the treatment of infections in patients who cannot receive any penicillin antibiotics.

Minocycline is used in the treatment of many differing bacterial infections, including gonorrhea, urinary tract infections (UTIs), skin infections, respiratory infections, tick fever, severe acne, chlamydia, amongst others.

Minocycline belongs in the class of medications known as tetracycline antibiotics. It works by killing off the bacteria or by preventing the growth of bacteria. This medication will not work in the treatment of colds, flu, or any other virus infections.

Minocycline injections can in some cases cause permanent discoloration of the teeth and a slowing down in the growth of the child's bones. This medication should not be administered to children younger than eight years old, unless specifically directed to by the child's health care provider.

Studies conducted in pregnant women have positively demonstrated that there is a risk to the fetus. However, there may be benefits of the treatment in life threatening situations or if there is presence of a serious disease that can outweigh the potential risk.

While using this medication during pregnancy can harm the unborn baby, the medication can also cause birth defects if the father is administered it when his sexual partner falls pregnant. If a pregnancy does occur while you are taking this medication, tell your health care provider immediately.

Birth control medication may also not work efficiently while you are taking minocycline. To prevent a pregnancy it is advised to use an additional form of birth control or contraception method. Other contraception includes: a diaphragm condoms, contraceptive gels or foam.

This medication can darken the color of your skin, eyes, nails, gums, teeth or scar tissue. Speak to your health care provider if you or your child have any further concerns.