Naproxen (Oral)


Due to its anti-inflammatory properties, Naproxen can be used to relieve muscle stiffness and swelling, as well as to minimize pain. Based on this, Naproxen is often used to treat acute conditions or temporary injuries, such as, bursitis, gout, kidney stones, menstrual cramps, tendonitis, and/or migraines.

In addition to this, Naproxen can be used to manage long-term conditions in some cases. Patients with rheumatoid arthritis, osteoarthritis, juvenile arthritis and/or ankylosing spondylitis, for example, may be prescribed Naproxen on an on-going basis. As these conditions are characterized by inflammation, Naproxen can reduce the joint inflammation itself and, therefore, relieve the pain caused by the condition. By minimizing the inflammation, Naproxen can also enable patients to regain movement in the affected joints.

As well as having pain-relieving and anti-inflammatory properties, Naproxen is also an antipyretic. Due to this, it can be used to relieve fevers and is often taken by patients when they have flu-like symptoms and/or an infection which is causing their temperature to increase.

As a non-selective cyclooxygenase inhibitor, Naproxen prevents the COX-1 and COX-2 enzymes from functioning normally. As a result, prostaglandin production in the patient's body is reduced. As prostaglandins are mediators of inflammation, a reduction in prostaglandins also equates to a reduction in the patient's symptoms.

In most cases, Naproxen is used as a short-term treatment for mild to moderate inflammation, pain, swelling or fever. However, if patients are required to take Naproxen on a long-term basis, they may be prescribed additional medication. Long-term use of Naproxen can have gastrointestinal side-effects and patients may be at risk of developing stomach or gastric ulcers. In order to prevent this, patients may be advised to take a proton pump inhibitor (PPI) when they are using Naproxen to treat a chronic condition, such as arthritis or ankylosing spondylitis.

Available in various forms, Naproxen can be taken as a capsule or tablet and may be taken in an extended-release format. In addition to this, Naproxen can be prescribed as a liquid which may be used by patients who are unable to swallow tablets or capsules.

Whilst Naproxen is effective in reducing pain and inflammation associated with short-term conditions, such as migraines, it is also beneficial for patients with on-going conditions. By prescribing Naproxen on a long-term basis, physicians can ensure that patients with joint pain, stiffness and swelling are able to obtain relief from their symptoms.

Conditions Treated

Type Of Medicine

  • Nonsteroidal anti-inflammatory drug (NSAID)

Side Effects

Patients can experience adverse effects when taking any type of medication but there are specific side-effects associated with the use of NSAIDs, such as Naproxen. In many instances, these side-effects will be more pronounced when patients first start using the medicine.

For example, patients may exhibit the following side-effects after taking Naproxen:

  • Sour or acid stomach
  • Continuing buzzing or ringing or other unexplained noise in the ears
  • Change in hearing
  • Hearing loss
  • Feeling of constant movement of surroundings or self
  • Swollen joints
  • Passing gas
  • Shaking or trembling of the feet or hands
  • Sensation of spinning
  • Trouble getting pregnant
  • Stomach discomfort or soreness
  • Trouble sleeping
  • Appetite changes
  • Trouble performing routine tasks
  • Numbness, burning, itching, crawling, prickling, tingling or "pins and needles"feelings
  • Itching, dry or burning eyes
  • Shakiness in the arms, legs, feet or hands
  • Difficulty with moving
  • Hearing, feeling or seeking things that are not there
  • Discharge from the eyes
  • Swelling, pain or redness of the eye, inner lining of the eyelid or the eyelid
  • Excessive tearing from the eyes
  • General feeling of illness or discomfort
  • Inability to concentrate
  • Muscle cramping, weakness, stiffness or aching
  • Loss or lack of strength
  • Unusual dullness, drowsiness or feelings of sluggishness
  • Menstrual changes

If the above side-effects are relatively mild, patients may not require medical intervention. However, if the side-effects persist or are severe, patients should access medical help.

In addition to this, patients will need to seek immediate medical assistance if they experience the following side-effects when taking Naproxen:

  • Belching
  • Night blindness
  • Bruising
  • Nausea or vomiting
  • Labored or difficult breathing
  • Halos around lights
  • Loss of appetite
  • Feeling of indigestion
  • Irregular, racing, pounding or fast pulse or heartbeat
  • Headache
  • Double vision
  • Itching skin
  • Disturbed color perception
  • Large, flat, purplish or blue patches in the skin
  • Decrease in urine-concentrating ability
  • Pain in the chest below the breastbone
  • Decrease in urine output
  • Skin eruptions
  • Indigestion
  • Stomach pain
  • Constipation
  • Swelling
  • Cloudy urine
  • Tightness in the chest
  • Bloating
  • Pains in the legs or back
  • Tarry, black or bloody stools
  • Anxiety
  • Loss of vision
  • Burning stomach or upper abdominal pain
  • Vomiting of material that looks like coffee grounds
  • Blurred vision
  • Unusual weakness or tiredness
  • Overbright appearance of lights
  • Unusual bruising or bleeding
  • Pale skin
  • Red pinpoint or purple spots on the skin
  • Tunnel vision
  • Severe and continuing nausea
  • Inflammation or swelling of the mouth
  • Trouble breathing with exertion
  • Severe stomach pain, cramping or burning
  • Bleeding gums
  • Rash on the skin
  • Blindness
  • Weight loss
  • Loosening, peeling or blistering or the skin
  • Canker sores
  • Blood in the stools or urine
  • Confusion
  • Blue fingernails and lips
  • Dry mouth
  • Change in the ability to see colors, especially yellow or blue
  • Dry skin
  • Chest discomfort or pain
  • Early appearance of swelling or redness on the skin
  • Clay-colored stools
  • Fluid-filled blisters on the skin
  • Cold sweats
  • Fever, may be with or without chills
  • Coma
  • Fainting
  • Confusion
  • Frequent urination
  • Cool, pale skin
  • Hoarseness or cough
  • Fruit-like breath odor
  • Coughing that sometimes produces a frothy pink sputum
  • Flushed, dry skin
  • Cracks in the skin
  • Greatly decreased amount of urine or frequency of urination
  • Darkened urine
  • High fever
  • Decreased vision
  • Hair loss
  • Depression
  • Hives
  • Diarrhea
  • Painful, burning or difficulty urination
  • Noisy, fast or difficult breathing
  • Increased hunger
  • Difficulty with swallowing
  • Increased thirst
  • Dilated neck veins
  • Increased sweating
  • Dizziness
  • Increased sensitivity of the skin to sunlight
  • Excess gas or air in the stomach
  • Increased urination
  • Extreme fatigue
  • Increased volume of diluted, pale urine
  • Sneezing
  • Eye pain
  • Slurred speech
  • Irregular breathing
  • Pain in the lower back or side
  • Muscle or joint pain
  • Large, hive-like swelling on the eyelids, face, lips, hands, throat, tongue, feet, legs or sex organs
  • Nosebleeds
  • Late appearance of rash, may be with or without weeping blisters that become crusted, especially in sun-exposed areas of skin, may also extend to unexposed areas
  • No breathing
  • Light-colored stools
  • No blood pressure
  • Lightheadedness
  • No pulse
  • Loss of heat from the body
  • Stomach upset
  • Pain in the knees or ankles
  • Stiffness in the back or neck
  • Nervousness
  • Burning or pain in the throat
  • Nightmares
  • Discomfort or pain in the jaw, arms, neck or back
  • Swelling of the fingers, lower legs, feet or face
  • Red, painful lumps under the skin, mostly on the legs
  • Swelling in the ankles and legs
  • Pains in the abdomen, side, or stomach, may radiating to the back
  • Stomach tenderness or cramps
  • Blue or pale skin, fingernails or lips
  • Pounding in the ears
  • Swelling or puffiness around the face, tongue, lips, eyes or of the eyelids
  • Weight gain
  • Shallow, rapid breathing
  • Irritated, red eyes
  • Red skin lesions, sometimes with a purple center
  • Weight gain
  • Red-green color blindness
  • Unexplained weight loss
  • Redness or other discoloration of the skin
  • Tiny bumps on the inner lining of the eyelid
  • Redness, soreness or swelling of the tongue
  • Unpleasant breath odor
  • Scaly skin
  • Painful, swollen or tender lymph nodes in the armpit, groin or neck
  • Seizures
  • Heaviness or weakness in the legs
  • Severe sunburn
  • Bloody or watery diarrhea
  • Shakiness
  • Yellowing of the skin or eyes
  • Skin thinness
  • Ulcers, white spots or sores inside the mouth or on the lips or tongue
  • Sore throat
  • Welting, sores or blisters
  • Spots on your skin, may resemble a pimple or blister

If patients experience any other side-effects when taking Naproxen, they should also obtain medical help. If patients develop symptoms which are not listed above, they can also report them to the Food and Drug Administration on 1-800-FDA-1088.

Patients should be aware that taking too much Naproxen or taking it too often can cause an overdose. If patients exhibit the following symptoms when taking this medication, they must seek urgent medical attention:

  • Bleeding under the skin
  • Muscle tremors
  • Confusion about place, time and identity
  • Sleepiness
  • Restlessness

If patients are aware that they have taken too much Naproxen, they should seek medical help straight away and not wait for the symptoms of an overdose to occur.


When patients are prescribed a nonsteroidal anti-inflammatory drug, such as Naproxen, their dose will depend on numerous factors. The patient's age, weight, medical history, condition and symptoms will all affect how much Naproxen they're prescribed. In addition to this, the format of the medication will affect how often the patient will need to take Naproxen. Delayed-release tablets should normally be taken less often than standard tablets, for example.

If adult patients are being treated for rheumatoid arthritis, osteoarthritis or ankylosing spondylitis, they may be prescribed Naproxen in various forms. If they are given Naproxen sodium in tablet form, patients are usually advised to take 275-550mg, twice per day. If required, the patient's dose may be increased but patients are not usually advised to take more than 1500mg of Naproxen sodium per day. Alternatively, patients may be prescribed Naproxen delayed-release tablets to treat these conditions. If so, patients are typically instructed to take 375-500mg, twice per day. If patients are prescribed Naproxen controlled-release tablets, they are generally advised to take 750mg-1000mg once per day.

If adult patients are being treated for rheumatoid arthritis, osteoarthritis or ankylosing spondylitis or children are being treated for juvenile arthritis, they may be prescribed Naproxen as a tablet or in oral suspension form. For adults, a standard dose is 250mg/10mL, 375mg/15mL or 500mg/20mL, twice per day. For pediatric patients over the age of two years, their dose will depend on their weight. Generally, pediatric patients are prescribed Naproxen at a strength of 5mg per kilogram of bodyweight, to be taken twice per day.

If adults are taking Naproxen tablets or oral suspension to relieve acute pain, such as tendonitis, bursitis or menstrual cramps, they are usually advised to take 500mg as an initial dose and then subsequent doses of 250mg every six to eight hours, as required. Alternatively, Naproxen controlled-release tablets can be prescribed for the treatment of acute pain. If patients are given Naproxen controlled-release tablets, they are usually advised to take 1000mg once per day, although a maximum of 1500mg per day may be prescribed for a short period of time. Alternatively, patients may be given Naproxen sodium in tablet form to relieve acute pain and, if so, they are usually instructed to take 550mg as an initial dose, following by 550mg every twelve hours or 275mg every six to eight hours, as required. If necessary, patients can be prescribed a maximum dose of 1375mg per day if their symptoms persist.

When patients are prescribed Naproxen for the treatment of gout, they can also be given various types of medication. If patients are prescribed Naproxen sodium to relieve the symptoms of acute gout, they are usually instructed to take 825mg as an initial dose, followed by 275mg every eight hours until the attack has subsided. Similarly, if patients are prescribed Naproxen tablets or oral suspension for the treatment of gout, they may be advised to take 750mg as an initial dose, followed by 250mg every eight hours until the attack has subsided.

If patients are prescribed Naproxen in a specific form, they should only take the medication in the relevant format. For example, patients should not use controlled-release tablets if they have been prescribed standard Naproxen tablets. These medications work in different ways and the risk of overdose increases is different formats are used.

Although the above dosing information reflects standard treatment regimes, patients should always follow their doctor's instructions when taking Naproxen. Whilst some patients may be prescribed Naproxen on a long-term basis, patients should not use this medication more often than they have been advised to.

If patients are prescribed Naproxen for long-term use, it may take some time for it to take full effect. Whilst most patients experience some symptom relief within a week of starting their medication, it can take some weeks before their symptoms are fully relieved.

When taking tablets or capsules, patients should swallow them whole and should not attempt to crush, break or open them. If patients are prescribed Naproxen as an oral suspension, they should also be given a measuring cup so that they can administer the appropriate dose. Patients should only use a measuring cup, medicine spoon or medicine syringe to administer liquid medication. Household spoons are unlikely to provide an accurate dose and should not be used to administer medication.

If patients forget to take a dose of Naproxen, they should take it as soon as they remember to. However, if their next dose is almost due, they should skip the missed dose. Patients must leave an appropriate amount of time between doses and each dose of Naproxen should normally be administered at least six hours apart. Patients should not attempt to take an extra or double dose of Naproxen, even if a previous dose has been missed.

If patients are unsure how to take this medicine or when to take their next dose of Naproxen, they should contact their physician or pharmacist for advice.

Potential Drug Interactions:

As Naproxen can interact with some other medications, patients should inform their doctor if they are using any other medicines, vitamins or supplements before they start taking this medicine. Due to the possibility of an interaction occurring, Naproxen should not prescribed in conjunction with:

  • Ketorolac

Similarly, the use of Naproxen alongside the following medications is not advisable:

  • Abciximab
  • Sodium Salicylate
  • Aceclofenac
  • Sulfasalazine
  • Acemetacin
  • Sulindac
  • Acenocoumarol
  • Tacrolimus
  • Amiloride
  • Spironolactone
  • Amineptine
  • Sibutramine
  • Amitriptyline
  • Tianeptine
  • Amitriptylinoxide
  • Tenoxicam
  • Amoxapine
  • Lepirudin
  • Amtolmetin Guacil
  • Lofepramine
  • Anagrelide
  • Levomilnacipran
  • Apixaban
  • Lornoxicam
  • Ardeparin
  • Lithium
  • Argatroban
  • Loxoprofen
  • Aspirin
  • Lumiracoxib
  • Balsalazide
  • Gossypol
  • Bemiparin
  • Hydrocortisone
  • Bendroflumethiazide
  • Hydroflumethiazide
  • Benzthiazide
  • Ginkgo
  • Beta Glucan
  • Hydrochlorothiazide
  • Betamethasone
  • Ibuprofen
  • Bismuth Subsalicylate
  • Imipramine
  • Bivalirudin
  • Iloprost
  • Bromfenac
  • Heparin
  • Budesonide
  • Meadowsweet
  • Bufexamac
  • Mefenamic Acid
  • Bumetanide
  • Methyclothiazide
  • Cangrelor
  • Melitracen
  • Celecoxib
  • Meclofenamate
  • Ceritinib
  • Meloxicam
  • Certoparin
  • Methotrexate
  • Chlorothiazide
  • Mesalamine
  • Chlorthalidone
  • Metolazone
  • Choline Magnesium Trisalicylate
  • Morniflumate
  • Choline Salicylate
  • Nabumetone
  • Cilostazol
  • Nadroparin
  • Citalopram
  • Milnacipran
  • Clomipramine
  • Nefazodone
  • Clonixin
  • Nepafenac
  • Clopamide
  • Naproxen
  • Cortisone
  • Parnaparin
  • Cyclopenthiazide
  • Olsalazine
  • Cyclosporine
  • Opipramol
  • Clopidogrel
  • Oxyphenbutazone
  • Dabigatran Etexilate
  • Oxaprozin
  • Dalteparin
  • Pemetrexed
  • Danaparoid
  • Paroxetine
  • Deflazacort
  • Parecoxib
  • Desipramine
  • Paramethasone
  • Desirudin
  • Pentoxifylline
  • Desvenlafaxine
  • Phenprocoumon
  • Dexamethasone
  • Phenyl Salicylate
  • Dexibuprofen
  • Piroxicam
  • Dexketoprofen
  • Phenindione
  • Diazoxide
  • Pixantrone
  • Dibenzepin
  • Polythiazide
  • Diclofenac
  • Piketoprofen
  • Diflunisal
  • Phenylbutazone
  • Digoxin
  • Pralatrexate
  • Dipyridamole
  • Prednisone
  • Dipyrone
  • Propyphenazone
  • Dothiepin
  • Prednisolone
  • Doxepin
  • Proquazone
  • Droxicam
  • Probenecid
  • Duloxetine
  • Prasugrel
  • Edoxaban
  • Proglumetacin
  • Enoxaparin
  • Reboxetine
  • Eplerenone
  • Reviparin
  • Epoprostenol
  • Rivaroxaban
  • Eptifibatide
  • Rofecoxib
  • Escitalopram
  • Salicylic Acid
  • Ethacrynic Acid
  • Salicylamide
  • Etodolac
  • Valdecoxib
  • Etofenamate
  • Vilazodone
  • Etoricoxib
  • Vorapaxar
  • Felbinac
  • Pentosan Polysulfate Sodium
  • Venlafaxine
  • Fenoprofen
  • Vortioxetine
  • Fepradinol
  • Tinzaparin
  • Protein C
  • Feprazone
  • Tolfenamic Acid
  • Feverfew
  • Ticagrelor
  • Floctafenine
  • Ticlopidine
  • Flufenamic Acid
  • Tirofiban
  • Fluocortolone
  • Torsemide
  • Fluoxetine
  • Tolmetin
  • Flurbiprofen
  • Fluvoxamine
  • Xipamide
  • Fondaparinux
  • Tiaprofenic Acid
  • Furosemide
  • Salsalate
  • Indapamide
  • Sertraline
  • Indomethacin
  • Ketoprofen
  • Treprostinil
  • Protriptyline
  • Magnesium Salicylate
  • Trimipramine
  • Methylprednisolone
  • Trolamine Salicylate
  • Niflumic Acid
  • Trichlormethiazide
  • Nimesulide
  • Triamterene
  • Nimesulide Beta Cyclodextrin
  • Warfarin
  • Nortriptyline

Although Naproxen is not normally used in conjunction with the above medications, it may be necessary in some cases. If so, the patient's dose may be altered or they may be instructed to take their medication at a specific time in order to try and prevent a drug interaction occurring.

If patients take Naproxen alongside any of the following medications, they may have an increased risk of experiencing side-effects:

  • Acebutolol
  • Labetalol
  • Alacepril
  • Levobunolol
  • Atenolol
  • Losartan
  • Azilsartan
  • Metoprolol
  • Azilsartan Medoxomil
  • Moexipril
  • Benazepril
  • Lisinopril
  • Betaxolol
  • Metipranolol
  • Bisoprolol
  • Perindopril
  • Candesartan
  • Pentopril
  • Carvedilol
  • Penbutolol
  • Captopril
  • Oxprenolol
  • Carteolol
  • Olmesartan
  • Celiprolol
  • Ramipril
  • Cilazapril
  • Practolol
  • Delapril
  • Sotalol
  • Enalapril
  • Quinapril
  • Enalaprilat
  • Temocapril
  • Eprosartan
  • Telmisartan
  • Esmolol
  • Spirapril
  • Fosinopril
  • Timolol
  • Imidapril
  • Valsartan
  • Irbesartan
  • Propranolol
  • Nadolol
  • Trandolapril
  • Nebivolol
  • Zofenopril
  • Pindolol

Patients should also be aware that interactions can take place between Naproxen and other substances. For example, patients should not use this medication alongside the following, due to the risk of an interaction occurring:

  • Tobacco

Once patients have started taking Naproxen, they should obtain medical advice before using any new medications, supplements and/or vitamins.


If patients have any existing health problems or a history of certain conditions, they should notify their physician before they start using Naproxen. There are some conditions which can affect the patient's use of these medications and these may include:

  • Heart surgery
  • Aspirin sensitivity
  • Fluid retention or body swelling (Edema)
  • Blood clots
  • Aspirin sensitive asthma
  • Heart attack
  • Bleeding problems
  • Anemia
  • High levels of potassium in the blood (Hyperkalemia)
  • Heart disease
  • Liver disease
  • Kidney disease
  • High blood pressure (Hypertension)
  • Intestinal or stomach bleeding or ulcers
  • Stroke

Although pediatric patients may be prescribed Naproxen, they are usually given the medication in the form of a tablet or oral suspension. However, the effects of Naproxen have not been specifically tested on patients under the age of two years. Due to this, Naproxen is not normally used to treat patients under this age and should not be used on any infants without medical advice being sought. Naproxen in controlled-release and delayed-release tablets have been specifically tested on pediatric patients. Due to this, these types of tablets are not usually prescribed to children or infants.

Naproxen can be prescribed to geriatric patients. However, older patients are more likely to have age-related health problems which could affect their use of this medication. In some cases, geriatric patients may be prescribed a reduced dose of Naproxen.

If patients are advised to take Naproxen on a long-term basis, they will need to have regular consultations with their physician. In addition to this, urine and blood tests may need to be performed to ensure that the medication is not having any unwanted effects.

Taking Naproxen can increase the patient's risk of having a stroke and/or heart attack. This is most likely to affect patients who already have heart disease and/or patients who have taken Naproxen for a long period of time.

When taking Naproxen, patients could suffer from intestinal bleeding and/or bleeding in the stomach. This side-effect can occur suddenly and without warning. Patients who have the following characteristics may be more likely to suffer from this side-effect when taking Naproxen:

  • Over the age of sixty years
  • History of stomach ulcers
  • Existing poor health
  • Smoker
  • Consumes alcohol regularly
  • Takes certain other medications, such as blood thinners and/or steroids

Patients could develop a serious liver problem when taking Naproxen and should obtain immediate medical help if they experience the following symptoms:

  • Loss of appetite
  • Dark urine
  • Pale stools
  • Tenderness or pain in the upper stomach
  • Nausea
  • Yellowing of the skin or eyes
  • Vomiting

Naproxen could cause the patient to exhibit a serious skin reaction. If patients develop the following symptoms, they should seek medical assistance:

  • Fever
  • Chills
  • Loosening, peeling or blistering of the skin
  • Diarrhea
  • Cough
  • Itching
  • Severe rash or acne
  • Muscle or joint pain
  • Sore throat
  • Red skin lesions
  • Unusual weakness or tiredness
  • Sores, white spots or ulcers on the lips or in the mouth

There are certain side-effects which may indicate the patient is suffering from a serious complication as a result of using Naproxen. If patients experience any of the following symptoms, they should access urgent medical help:

  • Tarry, black stools
  • Vomiting of blood
  • Swelling of the lower legs, feet, fingers or face
  • Vomiting of material that looks like coffee grounds
  • Severe stomach pain
  • Decreased urination
  • Yellowing of the eyes or skin
  • Unusual weight gain
  • Rash on the skin
  • Unusual bruising or bleeding

When taking Naproxen, patients may experience symptoms associated with a serious heart problem. If patients develop the following side-effects, they should obtain immediate medical assistance:

  • Tightness in the chest
  • Chest pain
  • Irregular or fast heartbeat
  • Weakness
  • Slurring of speech
  • Unusual warmth or flushing of the skin

If patients experience any changes to their vision when using Naproxen, they should consult their doctor immediately. This may include blurred vision, double vision or difficulty reading. In some cases, patients may be referred to an ophthalmologist so that a more in-depth assessment of their vision can take place.

If patients are due to undergo any medical tests, surgeries or medical procedures, they should inform the relevant healthcare practitioners that they are taking Naproxen. This includes any dental work the patient may be due to undergo. In some cases, patients may be advised to modify their dose of medication or to stop taking Naproxen days before the procedure is due to take place. However, patients should not attempt to make these changes themselves and should only alter their dosing schedule on the advice of a doctor.

Taking Naproxen can cause some patients to feel drowsy, lightheaded, dizzy or less alert than usual. If patients are affected in this way, they should not operate machinery, drive or carry out potentially dangerous tasks until these side-effects have passed.

Generally, Naproxen should not be taken by patients who are pregnant as it poses a risk to the unborn baby. Naproxen can be particularly harmful if it is taken during the later stages of a pregnancy.

If patients become pregnant when using Naproxen, they should inform their physician immediately.

In some cases, Naproxen can cause a delay in ovulation. This can affect the ability of female patients to conceive and have children. If patients plan to have children or are unsure about having children, they should discuss this with their physician before they start taking Naproxen.

Typically, some forms of Naproxen are thought to pose a minimal risk to infants if it is taken by a nursing mother. However, Naproxen is excreted in breast milk so a risk does still exist. Due to this, patients may prefer to abstain from breastfeeding whilst taking this medication. If patients are using Naproxen, they should obtain medical advice before breastfeeding.

However, the effects of Naproxen sodium on infants who have been exposed to this medication via breastfeeding have not been tested. Due to this, patients should not breastfeed whilst taking Naproxen sodium or while the medication remains in their system.

If patients are allergic to any substances or have every displayed an allergic reaction to anything, they should tell their physician before they start using Naproxen. In rare cases, Naproxen can cause patients to exhibit a serious allergic reaction, including anaphylaxis. This may be more likely to occur in patients who have previously had a reaction to other nonsteroidal anti-inflammatory drugs and/or aspirin. The symptoms of this time of reaction may include:

  • Difficulty swallowing
  • Difficulty breathing
  • Shortness of breath
  • Irregular or very fast breathing
  • Gasping for breath
  • Change of color of the skin on the face
  • Irregular or very fast pulse or heartbeat
  • Fainting
  • Swelling or puffiness around the eyes or of the eyelids
  • Hive-like swellings on the skin
  • Swelling of the tongue, throat, face, lips, mouth or hands

As an allergic reaction can be life-threatening, patients will require emergency medical treatments if they exhibit any of the above symptoms when taking Naproxen.


When patients are prescribed Naproxen, they should reach the manufacturer's instructions and medication guide carefully. These will state how the medication should be stored. In most cases, Naproxen can be kept at room temperature but should be protected from moisture, heat and direct light.

Patients should store Naproxen in a safe location, such as a locked medicine cabinet or a lockable medicine box, as this will prevent anyone else from accessing the medication. It is particularly important that children and/or pets cannot gain access to Naproxen, or any other medication which may be in the home.

If medicine is not in use, patients should dispose of it carefully. If the patient's supply of Naproxen reaches irs expiration date, for example, or if they are advised to stop taking Naproxen, they will need to dispose of it. However, medications should not be thrown out with regular household waste as they may pose a risk to other people. Instead, patients should contact their physician's office or pharmacist and make use of specialist medicine disposal route.


When patients take Naproxen, it is most-commonly used for the treatment of acute injuries and illnesses, such as tendonitis, migraines and/or sprains and strains. Due to its anti-inflammatory properties, Naproxen can be particularly effective when treating these types of conditions. However, patients should only use Naproxen for a relatively short period of time before seeking medical advice.

As Naproxen is available in various forms, the patient's treatment can be adapted to suit their needs. Patients with acute injuries or short-term pain may be advised to take standard Naproxen tablets, whilst patients requiring long-term treatment may be best suited to delayed-release or controlled-release tablets or capsules.

If patients are instructed to take Naproxen on a long-term basis, it is likely that they have a chronic condition. Although Naproxen can be used to manage the symptoms of rheumatoid arthritis, osteoarthritis, juvenile arthritis and/or ankylosing spondylitis, it will not cure these conditions. Despite this, Naproxen is effective in reducing the inflammation caused by these chronic conditions and, therefore, relieving the pain, stiffness and lack of mobility associated with arthritis, ankylosing spondylitis and other inflammatory disorders.