Neomycin, Polymyxin B, and Bacitracin (Ophthalmic)


Neomycin, Polymyxin B, and Bacitracin is an ophthalmic antibiotic combination medicine that is given to patients who are suffering from eye infections. You cannot obtain it on your own, but will instead require a doctor's prescription. This is because it is known to interact with other drugs and medical conditions. As such it is only suitable for certain patients. Your doctor will be able to fully assess the extent of your infection and decide which ophthalmic medicine is best. They can then advise you of any other dietary or lifestyle adjustments you need to make whilst taking Neomycin, Polymyxin B, and Bacitracin combination.

Condition(s) treated

  • Eye infections

Type of medicine

  • Ointment

Side Effects

As well as helping to clear up your eye infection, it is possible that Neomycin, Polymyxin B, and Bacitracin combination will cause other unwanted side effects. These side effects can range in their severity and need for medical assistance. If the side effects you are experiencing are minor, then you may simply find that they pass as your treatment progresses and your body adjusts to the medicine. However, there are some more serious side effects that require you to seek medical assistance. You should contact your doctor if you experience any of the following whilst taking Neomycin, Polymyxin B, and Bacitracin combination.

More common

  • Redness, swelling, itching, a rash, or another sign of irritation which was not present before using this medicine

It is possible that you could experience a serious allergic reaction after using this medicine. It is of course very rare, however here are the signs to look out for. Again, you should contact your doctor immediately if you experience these.

  • Swelling or itching (especially of the tongue, face, eyelid, eye, or throat)

You may find that after applying any eye ointment you experience some degree of blurriness in your vision. This is quite normal and is not necessarily a major cause for concern. This usually passes within a few minutes.


Below you can find the typical dosages of Neomycin, Polymyxin B, and Bacitracin combination which are prescribed to patients suffering from an eye infection. Do be aware however that the exact prescription you are given may differ greatly from what is listed below. This is because each patient is unique in their needs, and the prescription will be based off other factors as well. This includes the extent of your condition, other drugs you are taking, and other medical problems you suffer from.

You should follow the exact prescription as given to you by your doctor. If you have any questions about your prescription or think it should be altered at all, then you should address these concerns to the prescribing doctor. You should never make adjustments without approval.

  • Adults and children. Place a thin strip of the ointment into your eyes every three to four hours for a period of seven to 10 days.

You should aim to never miss a dose of this medicine as this will maximise the benefits you can expect to receive. However, if you do miss a dose for any reason, you should take the dose you have missed as soon as you are able. However, if it is then almost time for you to take your next dose, you should skip the missed one.

Here is some guidance on how to take the Neomycin, Polymyxin B, and Bacitracin combination properly.

  • Before doing anything you should wash your hands thoroughly.

In order to properly clear up your infection, you should continue to use this medicine for the full period as requested by your doctor. You should do this even if your symptoms appear to have cleared up. Again, be careful to try not to miss any doses.


It is possible that the Neomycin, Polymyxin B, and Bacitracin combination will cause an interaction to occur if taken alongside other medicines. In many cases, these interactions should be avoided as they are unwanted and may affect your treatment. For this reason, your doctor will require you to inform them of any and all drugs you are taking, be they prescription or nonprescription. In some cases, the interactions that occur may well be necessary as it is important you take both interacting medicines at the same time. Under such circumstances, your doctor may simply decide to alter the dose you receive of one or both. In either case, it is up to your doctor to come to this judgment and you should help by outlining all drugs you are using currently.

As well as interacting with certain drugs, it is possible that the Neomycin, Polymyxin B, and Bacitracin combination will interact with certain parts of your dietary intake. As such your doctor may ask you to make adjustments to what you eat, drink, or smoke whilst using this medicine.


Before prescribing you this medicine, your doctor will need to examine you to understand the full extent of your condition. As a part of this examination, they will need to know about any allergies you have. This includes any allergies to foods, dyes, preservatives, or animals.

As of writing, there is no pediatric-specific information regarding how this drug interacts children differently from adults. That is because it has mainly only been tested on adults.

Similarly, there is no geriatric-specific information to highlight how this would affect older patients differently to younger adults. If you are a geriatric patient, then your doctor is best placed to assess you for any increased risks and then weigh those risks against the benefits of using the drug.

Studies performed on pregnant women using the Neomycin, Polymyxin B, and Bacitracin combination have demonstrated that there is an increased risk to the fetus. Yoru doctor can explain this in more depth and then decide whether the benefits of using the medicine still outweigh any risks involved.

There are currently no adequate studies that have been performed on breastfeeding women using this medicine. Your doctor can advise on any risks and weigh them against the benefits with you.

If you find that your symptoms don't improve, or get worse, over the first few days of using this drug, then contact your doctor.


You should keep this medicine stored in a closed container and kept at room temperature. It shouldn't be allowed to freeze or be exposed to heat, direct light, or moisture. It is also unsafe for children so should be stored safely out of reach. Once you have finished your treatment, you should dispose of any remaining medicine in a safe and sensible manner. Similarly, if you have any medicine that goes out of date, you should also dispose of this. If you need assistance in knowing how to safely dispose of medicine, you can ask your doctor or pharmacist.


If you are currently suffering from an eye infection, then Neomycin, Polymyxin B, and Bacitracin combination is just one type of medicine that may have been prescribed to your to help relieve the symptoms and treat the problems. However, do be aware that this drug is not well suited to every patient and is only chosen for certain people. To decide suitability, your doctor will need to first give you a full medical examination.

They will be able to advise you clearly on how much of this medicine you should take and for how long. They may also advise you to make certain changes to your lifestyle or diet. If this is the case then you should follow all recommendations to the best of your ability. If you have any other questions about your treatment, you should address these to your doctor.