Nystatin (Topical)


Nystatin in topical form is prescribed as a skin-based treatment for certain forms of fungal infection in most parts of the body. Nystatin functions as an effective type of antifungal and reduce and removes the symptoms and appearance that is associated with fungal infection.


A primary form of treatment for fungal infection, Nystatin is used for many different parts of the body in order to reduce and remove fungal conditions. It is an effective form of antifungal used in both the US and Canada.

Nystatin topical medication is branded in the US under the following names:

  • Mycostatin
  • Nystop
  • Pedi-Dri

Nystatin is solely available through a prescription from your doctor or a relevant medical professional. It is not an over the counter product and as such is often more effective than the topical forms of medication available in drug stores and supermarkets.

Conditions Treated

  • Fungal infection

Type Of Medicine

  • Powder
  • Cream
  • Ointment

Side Effects

There are several required effects of Nystatin, including the reduction of fungal infections, providing both relief and reducing and eventually moving the severity of a fungal skin condition. As well as these necessary and required effects, using Nystatin may also result in unexpected, unwanted or unneeded side effects as a result of its use. It is very unlikely that you will experience every side effect. However, if you do experience any of the listed effects, even if it is just a single one, it's important that you talk to your doctor as soon as you can.

Should you experience any of the listed effects while you are prescribed Nystatin in topical form, you should talk to your doctor as soon as possible in order to discuss ways to resolve or avoid these effects in the future:

  • Skin irritation following the use of Nystatin
  • Vaginal burning or itching not present before use of this medicine

As well as the above listed, you may experience other side effects that have not been included. These may be due to your medication, or any other combination of factors. If you experience other side effects, consult with your doctor on the cause, and they will be able to advise you on what to do next, or how to avoid these effects

The primary person you should inform regarding any side effects should be your doctor or a relevant trained medical professional, who will be best placed to help you with any issues or conditions you may be experiencing. In addition, you can report your side effects directly to the FDA on the number 1-800-FDA-1088.


Due to the varying forms of fungal infection Nystatin is used for, the dosage of this medication will vary from patient to patient. The below dosage is just a guideline, and your primary source of information on your level and amount of dosage should come directly from your doctor, and be included in the directions on your prescribed medication's label. If your dose varies from what is listed below, do no change the way you take your medication unless told to do so by your doctor.

The amount of topical Nystatin you take each day can vary depending on several different factors. This may include the overall strength of the medication you are prescribed, as well as other variables such as the number of doses you are prescribed on each day, the time between your doses and the length of time you are prescribed Nystatin for. All these may depend on why you are taking this medicine, and for what condition.

For topical dosage forms (cream or ointment):

  • For fungus infections:

O Apply to the affected area(s) of the skin two times a day.

For topical dosage form (powder):

  • For fungus infections:

O Apply to the affected area(s) of the skin two or three times a day.

Should you forget or miss a dose of Nystatin in topical form, you should resume your schedule as soon as you possibly can. However, if it is nearly time for the next dose of your medication, skip the dose that you have missed and return to your regular prescribed schedule. Never double your dose of this medication.


Certain drugs should not be used at the same time as each other. This is because, when it comes to certain functionalities and types of medicine, an interaction may result - that can vary a great deal in severity based on a level of interaction and dosage. In certain cases, your doctor may decide to look in closer detail at the dosages and times taken of all your prescribed medicines, and advise you on precautions that can be taken to avoid interaction. In some cases, it may be required that you stop or change a form of medication.

When this medicine is prescribed to you, it is important that your doctor is completely aware of your medical history. This should include any and all medications you are currently taking, or have recently taken, which includes over the counter medicines, herbal supplements and even vitamins. This ensures your doctor has an informed decision regarding you taking Nystatin based on your past history.

Using Nystatin as a treatment for fungal infection when taking other medications can result in an increased risk of side effects and interaction. However, in some cases taking these medicines together may be the best course of treatment for you. If both of these drugs are prescribed at the same time, your doctor will be able to advise you on the best way to take them together.

There are no known specific interactions between Nystatin and other medications. However, it is still critically important that you provide your doctor with a complete and full medical history, in order to avoid any possible side effects, interactions or problems with future medications.

Specific medicines cannot be taken or used around specific eating schedules, due to their possible interaction with food. Eating certain types of food, or consuming tobacco or alcohol during the time of taking certain medications can also result in side effects or interactions that vary in severity. It's important that your doctor has knowledge about and is aware of your diet, and your consumption of tobacco and alcohol, prior to your prescription of any medication.

Nystatin has no known interaction problems with food, alcohol or tobacco. In addition, this medicine does not appear to have any negative interactions in regard to pre-existing medical conditions or illnesses. Despite this, it is important that your doctor knows your full medical history in order to make informed and safer decisions about your prescribed medication.


In choosing to use Nystatin as a way to reduce and eliminate fungal infection, the risks of taking this medicine must be weighed against the good it will do, and the harm it may cause the patient. This is a decision you and your doctor can make between you, to ensure both parties are happy to continue with this form of medication. For this medicine, the following should be considered:

If you've ever experienced an unusual, bad or seemingly allergic reaction to this medication of any medications similar, it's important that you inform your doctor of this prior to taking Nystatin. As well as medical allergies, it's also important that your doctor is aware of any allergies you have in general, including to dyes, preservative, animals or foods. If you know you are allergic to a particular item or type of food, ensure you read the ingredients on over the counter medications to reduce the chance of harm.

There has been no specific studies or information regarding the use of Nystatin as a topical formula on children in any age group. However, Nystatin is not expected to cause any different problems or effects in comparison to the adult use of this medication. In addition, in geriatric or older patients, there have also been no specific studies - but as with pediatric patients, it is unlikely that there will be alternative effects as a result of this.

Nystatin as a treatment should not be used as a way to treat any form of systemic, oral, intravaginal or ophthalmic infections, as this medication is not designed for this purpose, and may cause skin problems as a result.

Nystatin is listed as FDA Category C. This indicates this it is unknown if this medication causes fetal harm when used during pregnancy, or if it can affect reproductive capabilities. This risk should be discussed with your doctor if you are pregnant or planning to become pregnant prior to you taking this medication. It is also unknown if Nystatin can be passed through breastfeeding, so caution should be taken when using this medication.


Nystatin should be stored in a safe, closed container at room temperature, and kept away from any form of heat, moisture, and direct light. This medicine should never be frozen.

Never keep outdated medications or drugs that are no longer needed.


As a primary treatment for skin based fungal infections, Nystatin is used on many parts of the body. This medication comes in cream, powder and ointment forms in order to provide both varying dosage levels and appropriate form of application.

This medicine is used both in the US and Canada as a form of treatment and is used for all ages.