Nystatin and Triamcinolone (Topical)


Nystatin and triamcinolone is a combination drug that contains a corticosteroid and an antifungal.

Antifungals are used in the treatment of infections caused by a fungus. They work by preventing the growth of the fungus or killing it. This medication will not work for other types of infections.

Corticosteroids are part of the family of medications known as steroids. They are used to help relieve swelling, redness, itching, and other discomforts of many skin problems.

This medication is used to help relieve the discomfort of infections and treat specific fungus infections, such as Candida.

Topical corticosteroids can sometimes cause serious side effects, but this is rare. These side effects are more likely to occur in children as they are more susceptible to absorbing more of the medication. Before using this medication in children, it's a good idea to speak with your doctor about this potential risk. You cannot obtain this medication on your own, you need to obtain it via a prescription from your doctor. This drug is available in the dosage forms of cream and ointment.

Conditions treated

  • Skin infection due to a Candida yeast

Type of medication

  • Topical solution (cream and ointment)

Side effects

Along with treating infections caused by a fungus, this drug combination could produce some unwanted side effects. Not all of these side effects may be present, but if they do occur, you may need to seek some medical attention.

You should seek advice from a doctor or healthcare professional right away if you suffer from any of the following side effects while taking nystatin/triamcinolone topical:


  • Burning, blistering, dryness, peeling, itching, or other signs of irritation that are not present before you used this medication

Seek advice from your doctor right away if you suffer from any of the following side effects while taking nystatin/triamcinolone topical:

The majority of the above side effects are more likely to occur in young children, who are at risk of absorbing larger amounts of this medication.

This is not a complete list of all the different side effects possible with the use of this drug and you may find you suffer from some side effects that are not included above. If you notice anything unusual, it's best to seek advice from a doctor or healthcare professional.


The final dose of all medications will depend on a number of factors based on individual experience. This will include your weight, age and height, other medications you are currently taking and any other medical conditions that you suffer from. The amount of medicine that you take will also depend on the strength of the medicine, the number of doses you are required to take daily, the length of time between doses and the duration you are taking the medication for.

For fungus infections

For cream dosage form: Adults and children should apply the cream to the affected area(s) of the skin twice daily in the morning and then in the evening.

For ointment dosage form: Adults and children should apply the ointment to the affected area(s) of the skin twice or three times daily.

Only take this medication as directed by your doctor. If you take more of this medication then you could increase your risk of side effects and if you take too little, you could reduce the effectiveness of the drug combination.

Don't be alarmed if you miss a dose of this medication. You should apply it as soon as you remember. The exception to this is if it's almost time for your next dose. If this is the case, you should skip the missed dose and revert back to your original dosing schedule.


There is the potential for this drug combination to interact with other drugs you are currently taking. These interactions can cause both unwanted side effects and reduce the effectiveness of either drug you are taking. This is why it's important to give your doctor a complete list of all the current and past medications you are taking including prescription, nonprescription drugs, vitamins supplements and herbal products. It's also a good idea to let your doctor know about any other medical conditions you are currently suffering from, as this can increase the risk of interactions occurring.

The use of this medication alongside any of the following medications is not typically recommended. Your doctor may avoid treating you with this drug altogether or alter some of the other medications you are taking.

The use of this medication alongside any of the following medications is again, not typically recommended. However, in some cases, it may be required for your treatment. If you are given both medications at the same time, your doctor may alter the dose or frequency in which you use both or either drug.

  • Aldesleukin

The use of this medication alongside any of the following drugs can increase your risk of specific side effects, but the use of both drugs may be required for your treatment. If you are prescribed both medications together, your doctor may change the frequency or dose of which you receive both or one of the medications.

  • Pefloxacin

This list is not complete and there could be other drugs that interact with the use of Nystatin and Triamcinolone.

  • Vaccinia (cowpox)


Allergies You should let your healthcare professional or doctor know if you have ever suffered an unusual or allergic reaction to this medication or similar medications. You should also make them aware of any other allergies you suffer from including to animals, preservatives, dye, and foods.

Pediatric population

Children can be particularly sensitive to the effects of this drug combination. This, therefore, can increase the risk of children obtaining side effects. It's therefore important that you discuss with your child's doctor the benefits and risks associated with using this medication

Geriatric population

Many medications have not specifically studied the use of this drug in the older population. Therefore, it is unknown whether the drug combination will work exactly as it would do in younger adults. Although there is no specific information that compares the use of topical nystatin and triamcinolone combination in geriatric population with use in other age groups, this medication is not expected to cause a variation in problems or side effects in older people than it does in the younger population.

Use in pregnancy and breastfeeding

This drug is under FDA pregnancy category C which means it is currently unknown whether nystatin and triamcinolone topical can harm an unborn infant. Let your doctor know if you are currently pregnant or intend on becoming pregnant whilst taking this medication. It is also unknown whether this drug can pass into breast milk or if it could harm a nursing infant. You should let your doctor know if you are currently breastfeeding a baby and discuss the associated risks.

To ensure that your infections clear up completely and do not reappear, you need to commit to good health habits. Keep the area that in affected as dry and cool as you possibly can.

If your skin problem doesn't begin to improve within two or three weeks, or if it becomes worse, you should seek advice from your doctor or a healthcare professional.

The corticosteroid in this medication can be absorbed through the skin and is more likely to cause side effects in young children. The long-term use of this drug combination could affect development and growth, so it's important that children are monitored closely by their doctor.

For diabetic patients suffering from both type 1 and type 2 diabetes: The corticosteroid contained in this medication could cause higher urine sugar and blood sugar levels. Although this is rare. You should consult with your doctor before altering your diet or increasing the dose of your diabetes medication.

Proper use

Don't use this medication in or around the eyes.

You should consult with your doctor before using this medication to treat any other skin problems. It should not be used for a virus or bacterial infection. Also, this drug can only be used on specific fungus infections of the skin.

Apply a thin layer of this medication to the affected area and rub in thoroughly and gently.

You should not wrap, bandage or apply an airtight covering over this medication unless you have been told to do so. This is because the use of airtight covering can increase absorption of the medication and the chance of irritation alongside other side effects. You should also wear loose-fitting clothing when using this medication around the groin area. If using this medication around the diaper area of children you should avoid the use of plastic pants and tight-fitting diapers.

To help your infection clear up completely, you need to use this medication for the full treatment, even if your symptoms have begun to clear up. Do not miss any doses. It's also important that you do not use this medication for longer than has been advised by your doctor. If you do, you will increase your absorption of the medication which could result in stretch marks and thinning of the skin.


This medication should be stored in a closed container and kept at room temperature. It should also be kept away from moisture, heat, and light. Prevent this medication from freezing. It's also important to keep this medication out of the reach of small children. Do not keep medication that has passed its expiry date or you no longer need. You should contact your local pharmacist for advice on the best method of disposal for this drug once you have finished treatment.


When used correctly, this drug combination is successful in the treatment of skin infections caused by a yeast or fungus. Due to a large number of interactions possible with this drug, it's vital that you give your doctor or healthcare professional a full list of all the current medications you are taking. The use of this drug in children should be monitored carefully as they are at a higher risk of absorbing greater amounts of this medication which could affect their growth and development as well as increase their risk of side effects. You should discuss with your doctor the potential benefits and risk of using this drug in a child. You should let your doctor know if you are currently pregnant or intend on breastfeeding whilst using this medication. If you stop taking this medication earlier than required, you could allow the fungus to continue to grow, which can result in a return of the infection. If your symptoms do not begin to improve within one week, you should seek advice from a doctor. If you require any further information about the practical uses of Nystatin and Triamcinolone topical drug combination or you have any questions, you should contact your local healthcare professional or doctor for advice.