Olmesartan (Oral)

Overview

Olmesartan is a drug used either alone or in combination with other medications to treat hypertension (high blood pressure). When you suffer from high blood pressure, this adds to the workload of the arteries and heart. If it continues for a prolonged period of time, the arteries and heart may not function properly. This can result in damage to the blood vessels of the heart, brain, and kidneys, which could result in heart failure, a stroke, or kidney failure. By lowering the blood pressure we can reduce the risk of heart attacks and strokes occurring.

This drug is an angiotensin II receptor blocker. It works by blocking a substance within the body that forces the blood vessels to tighten. Olmesartan counteracts this by relaxing the blood vessels. This helps increase the supply of oxygen and blood to the heart and lowers blood pressure. You cannot obtain this medication on your own. It is only available via a prescription from your doctor. It is available in the dosage form of tablet for oral consumption.

Conditions treated

  • High blood pressure

Type of medicine

  • Oral tablet

Side effects

Alongside treating high blood pressure, this drug can also produce some unwanted side effects. However, not all of these side effects may occur at the one time, but if they do occur you may require medical attention.

Consult with your doctor right away if you suffer from any of the following side effects whilst taking Olmesartan:

Less common

  • A cough or a cough producing mucus

Rare

  • Swelling or bloating of the arms, face, hands, lower legs, or feet

Incidence not known

  • Dizziness

Seek emergency help right away if any of the following symptoms of overdose occur:

Symptoms of overdose

  • Sweating

Some of the side effects that occur that with this drug, usually don' require medical attention. You typically find that these side effects begin to reduce during treatment as your body begins to adjust to the medication. Also, your local pharmacist may be able to inform you about various ways to reduce or prevent some of these side effects. Seek advice from your health care professional or doctor if any of the following side effects linger or become bothersome

Less common

  • Unexplained weight loss

Rare

  • Tingling in the feet or hands

Incidence not known

  • Loss or lack strength

You may suffer from other side effects that are not listed above. You should seek advice from your doctor if you notice anything strange or unusual. Other side effects not listed may also occur in some patients. You can report all side effects regardless of severity to the FDA on 1-800-FDA-1088.

Dosage

The final dose of all medications will be dependent upon a number of individual factors as well as specifics about the medication itself. Your doctor will take into account your age, weight and height, any other medical conditions you suffer from including any corresponding medications you take for treatment. The strength of the medication and duration of treatment will also be taken into consideration, as well as your reaction to the first dose. The following doses are only guidelines and you should not be alarmed if your dose is different. Don't alter your dose without advice from your doctor or healthcare professional. If you take too much of this drug you could increase your risk of overdose or severe side effects and if you take too little, you could limit the effectiveness of this drug in its treatment.

For oral dosage form (tablets) for the treatment of hypertension.

Adults: Initially a dose of, twenty milligrams once daily. Your doctor can increase your dose when necessary. However, typically, the dose does not exceed more than forty mg per day.

Children 6 to 16 years old weighing 35 kilograms or more: The dose is based on body weight and will be determined by your doctor. However, the typical dose is usually twenty to forty mg once daily. If the child can't swallow the tablets, then it's recommended they receive an oral suspension.

Children 6 to 16 years old weighing at least twenty kilograms and less than 35 kg: The final dose is based on body weight and will be determined by your doctor. However, typically the dose is usually ten to twenty mg once daily. If the child can't swallow the tablets, then it's recommended they receive an oral suspension.

Children one to five years old: The use and dose will be determined by a doctor.

Children younger than one year of age: This drug is not recommended for use in those younger than one year old.

Missed Dose

If you miss a dose of Olmesartan, you should take it as soon as you remember. However, if it's almost time for your next dose, you should skip your missed dose and proceed to continue your regular dosing schedule. Don't double your doses to rectify a missed dose.

Interactions

This drug can interact with a variety of other drugs which could produce severe side effects alongside reducing the effectiveness of either drug in its treatment. To help limit the risk of these interactions occurring, it's important to give your doctor or healthcare professional a full list of all the medications you are currently taking, and those you have taken in the past. This list should include all over the counter drugs (both prescription and nonprescription), all herbal products and vitamin supplements. It's also important to inform your doctor of any other health conditions you may suffer from as these too could increase the risk of interactions occurring. In some cases, you doctor will try to avoid interactions occurring, but in certain circumstances, the use of both drugs may be the best treatment plan for you.

The use of this medication alongside any of the following medications is not typically recommended. Your doctor may avoid treating you with this drug altogether or alter some of the other drugs you are taking.

  • Aliskiren

The use of this medication alongside any of the following medications is not typically recommended, but in some cases, it may be required. If you are given both medications at once, your doctor may alter or change the dose or frequency of either medication you are using.

  • Enalaprilat

The use of this medication alongside any of the following drugs could increase your risk of certain side effects. However, in some cases, this may still be the best treatment plan for you. If you are prescribed both medications together, your doctor may alter the dose or frequency in which you use either drug.

  • Colesevelam

The following drugs can produce both severe and moderate interactions. Let your doctor know if you are currently taking any of the following drugs:

  • Ketoprofen

This list is not complete, so, therefore, it's important to mention all medications you are currently taking to the healthcare team.

Other Interactions

Some medicines cannot be used at the time of eating or eating specific foods as it could increase interactions. This is the same for the use of alcohol and tobacco. You should discuss with your doctor the use of your medication alongside alcohol, food, and tobacco.

Other Medical conditions

When you suffer from other medical conditions, this too can increase your riks of interactions and may affect the overall use of Olmesartan. You should inform your doctor or healthcare professional about any other medical conditions you suffer from, especially:

  • Kidney disease

Warnings

Before deciding to use a medication, the risks of taking Olmesartan must be weighed against the good it will do. You will make this decision alongside your doctor. Below are some of the decisions you need to consider.

Allergies

It's important to let your doctor or healthcare professional know if you have ever suffered from an allergic reaction to this medication or similar medications. You should also make them aware of any of allergies you suffer from including to animals, preservatives, dye, and foods.

Pediatric population

Appropriate studies that have been conducted to date have not indicated a pediatric-specific problem that could limit the usefulness of this medication in children. However, this drug has not been shown to be effective in children younger than six years old. Olmesartan should not be used in children younger than one year of age as the safety and efficacy have not been established.

Geriatric population

Appropriate studies conducted to date have not indicated a geriatric-specific problem that could limit the usefulness of this drug in the elderly population.

Use in pregnancy and breastfeeding

This drug is under FDA pregnancy category D. You should not use this medication if you are pregnant. If you become pregnant, you need to stop taking this medication immediately and tell your doctor urgently. Olmesartan can cause death or injury to the unborn baby if you take it during your second or third trimester. Use an effective form of birth control to prevent yourself from falling pregnant whilst using this medication.

It's unknown whether olmesartan can pass into breast milk or if it will harm a nursing infant. You should avoid breastfeeding whilst you taking this medication.

It's extremely important that your doctor monitors your progress during regular appointments to ensure this medication is working as it should do. Your doctor may use urine and blood tests to check for unwanted effects.

Lightheadedness or dizziness can occur after the first dose of this medication, especially if you have been taking a water pill (diuretic). Ensure you know how you react to this medication before you use machinery, drive, or do anything else that could be dangerous if you are dizzy.

Check with your doctor immediately if you or your child falls sick whilst taking this medication, especially with continuing or severe or diarrhea and vomiting. These conditions could cause you to lose too much water and may cause low blood pressure. You can also lose water when you exercise or are in hot weather, so drink plenty of fluids.

Chronic and severe diarrhea coupled with weight loss could develop months to years after taking this medication. Let your doctor know immediately away if you suffer from any of these symptoms.

Storage

Olmesartan should be stored in a closed container and kept at room temperature. It should be hidden away from moisture, heat, and light. Prevent this drug from freezing. Keep this drug out of the reach of children.Don't keep any medication that has passed its expiry date or you no longer require. You should speak with your local pharmacist for advice on the best method of disposal for a medication you no longer need.

Summary

When used correctly, this drug is successful in treating high blood pressure. Due to the number of interactions that can occur with other drugs, it's important that you give your doctor a complete list of all the medications and conditions you suffer from. This drug should not be used in children aged younger than one year old. Safety and efficacy have not been established. You should not use this drug under any circumstances when pregnant, this drug can cause severe harm or death to your unborn child. Take precautions to prevent pregnancy whilst using this drug and inform your doctor urgently if you fall pregnant whilst taking this drug. You should avoid taking this drug whilst breastfeeding. If you think you have overdosed on this medication, seek medical attention right away. Do not take more of this medication than you have been instructed to do so as it could increase your risk of severe side effects. Never share your medication with anyone else. If you require any further information about the practical uses of this medication, or you have any other questions, then contact your local healthcare professional or doctor for further advice.