Olopatadine (Nasal)

Olopatadine nasal is used for the treatment of symptoms such as sneezing, congestion and a runny nose caused by seasonal allergies.


Olopatadine nasal spray is used in the treatment of symptoms of seasonal allergic rhinitis, such as a runny or itchy nose, sneezing, or itchy eyes. It's an antihistamine and it works in the prevention of the release of histamine in the body. This drug will also block the effects of histamine, which prevents the symptoms of the allergy. You can only obtain this medication via a prescription from your doctor. It is available in the dosage form of a spray.

Conditions treated

  • Seasonal Runny Nose

Type of medication

  • Nasal spray

Side effects

As well as the intended effects of treating hay fever, this drug can produce some unwanted side effects. Not all of these may be present, but if they are, you may need to seek medical attention.

Check with your doctor right away if you suffer from any of the following side effects whilst taking Olopatadine:

Less common


  • Loss of appetite

Incidence not known

  • Swelling of the throat, face, or tongue

Seek emergency help right away if you suffer from any of the following symptoms of overdose.

Symptoms of overdose

  • Restlessness

Some side effects that occur with this drug don't typically require medical attention. Usually, these side effects begin to disappear as your body starts to adjust to the medication. Your healthcare professional may be able to let you know about ways to reduce or prevent some of these side effects. You should check with your healthcare professional if any of the following side effects linger or cause you bother.

More common

  • Bitter taste


  • Throat irritation

Incidence not known

  • Thirst

You could suffer from other side effects that are not listed above. You should seek medical advice if you notice anything strange. You can report all side effects to the FDA.


The final dose of this medication will depend on your weight, age, and height, other medical conditions you suffer from including any corresponding medication you take to treat them. Your doctor will also consider the strength of the medication, the length of time for treatment and your reaction to the first dose. The following doses are only guidelines. Your final dose may vary.

For nasal dosage form (spray) for the treatment of hay fever:

  • Adults, teenagers, and children twelve years of age and older: two sprays in each nostril twice daily.
  • Children six to eleven years of age: one spray in each nostril twice daily.
  • Children younger than six years old: The use and dose will be determined by a doctor.

Missed Dose

If you miss a dose of Olopatadine you need to take it as soon as possible. Although, if it's close to the time of your next dose, you should skip the dose you have missed and return to your original dosing schedule. Don't double your doses to rectify a missed dose.

Proper Use

Do not take more of this medication than has been indicated by your doctor. If you take too much of this drug you could increase your risk of side effects, whereas if you take too little, you could reduce your treatment. Don't use this drug for longer than has been prescribed.

This medication comes with patient instructions. You should read and follow these carefully and if you have any questions, contact your doctor.

This medication is for use only in the nose. Don't get it on your skin or in your eyes. If it does appear in these areas, you need to rinse it off immediately with water.

To use:

Before you use this spray for the first time, it needs to be primed. To do this, pump the bottle five times or until the spray comes out. It is now ready for use.

If you do not use the bottle for seven days or longer, you should re-prime it by releasing two sprays.

Before using the spray, you need to blow your nose gently to help clear your nostrils.

After you have finished with the spray, you should wipe the tip of the bottle with a clean tissue and replace the cap.


Drug interactions can occur with this medication. These can reduce the effectiveness of this drug in your treatment or even increase your risk of serious side effects. To help limit the risk of these interactions occurring, you should make your health care team aware of any medical conditions you suffer from and any corresponding treatment you take for them. This list should include any vitamin supplements, prescription and non-prescription drugs and herbal products. Your healthcare team will do their best to avoid treating you with this drug when possible, but in some cases, it may still be necessary.

The use of this medication alongside any of the following is not typically recommended, but in some cases, it may be necessary. If you are given both medications together, your doctor may alter the dose or frequency in which you use either medication.

  • Donepezil

Let your doctor know if you are taking any of the following medications:

  • Diazoxide

This list is not complete, so it's important to inform your doctor about every medication you are taking.

Other Medical Problems

The presence of other medical conditions could affect the use of this medication. Ensure that you let your healthcare team know if you suffer from any other medical conditions including:

  • Injury to the inside of the nose


Before you commit to taking a medication, there are a number things to consider beforehand. Below are some precautions to take into consideration before using Olopatadine.


Make your doctor aware if you have ever suffered from an allergic reaction to this medication or similar medications. You should also make them aware of any other allergies you may suffer from including to dyes, preservatives, food or animals.

Pediatric population

Studies have not yet been conducted studying the relationship of age to the effects of this drug in those who are younger than six years old. Therefore efficacy and safety have not yet been established.

Geriatric population

Appropriate studies conducted to date have not indicated a geriatric-specific problem that could limit the effectiveness of olopatadine in the elderly population. However, elderly patients are more likely to have age-related kidney, liver or heart problems, which could require a degree of caution to be exercised or an adjustment in the dose for patients receiving this drug.

Use in pregnancy and breastfeeding

This drug is under FDA pregnancy category C. It's currently unknown whether this drug can harm an unborn baby. You should make your doctor aware if you are pregnant or intend on becoming pregnant whilst using this drug.

It's unknown whether this drug passes into breast milk or if it could harm a nursing infant. Don't use this medicine without telling your healthcare team if you are breastfeeding an infant.

It's extremely important that your doctor monitors your progress and the progress of your child at regular appointments for any unwanted side effects or problems that could occur with this drug.

This medication can increase your risk of suffering from nasal problems. You should consult with your doctor immediately if you or your child have sores inside the nose, bloody mucus, or unexplained nosebleeds whilst you are using this medication.

This medication will add to the effects of CNS depressants (medications that made you less alert or drowsy) or alcohol. Different types of CNS depressants include medications or antihistamines for hay fever, cold, allergies, tranquilizers, sedatives, or prescription pain medicine, sleeping medicine or narcotics, medication for barbiturates or seizures, anesthetics or muscle relaxants. Consult with your medical dentist or doctor before taking any of the medications above while you or your child is taking this medication.

This medication can cause some people to become drowsy, dizzy, or less alert than normal. If any of these side effects occur, don't use machinery, drive, or do anything else that could be dangerous if you are not alert or feel dizzy.

If you or your child's symptoms don't improve within a few days or if they worsen, seek advice from your doctor.


Olopatadine should be stored in a closed container at room temperature and kept away from moisture, heat or light. Do not let this medication freeze. Keep this drug out of the reach of children. Dispose of medication that has passed its expiry date or you no longer require. Seek advice from your local pharmacist for the best method of disposal for the medication you no longer need.


When used as directed, this drug is successful in relieving the symptoms associated with seasonal allergies. There are a large number of interactions possible with this medication, so it's important that your doctor is aware of every medicine you are currently taking. This drug should not be used in those under six years old as safety and efficacy have not been established. You need to use this medication regularly to obtain the peak benefit from it. To help you remember, you should use it at a similar time each day.

You should let your doctor know if you are pregnant whilst using this drug, or you are currently breastfeeding. Only take the amount of medication that has been prescribed to you, to take more could increase your risk of serious side effects. You should let your doctor know if you or your child's symptoms are not improving whilst using this medication.

Do not share this medication with anyone else. If you require any further information about the practical uses of this medication in treatment, or you have any more questions or queries, then get in touch with your doctor or healthcare professional for more advice.