For patients who are on dialysis and suffering from chronic kidney disease, Peginesatide may be given via an injection in order to treat anemia.
Be aware that you can only access Peginesatide following a doctor's prescription. Also note that on February 24th 2013, this medicine was withdrawn voluntarily from the U.S market followed by safety concerns surrounding serious allergic reactions.
As well as helping to treat anemia, it is possible that Peginesatide will cause patients to experience unwanted side effects. These side effects can range in their severity and the need for medical assistance. Be aware that you may experience multiple side effects or you may experience none at all. Directly below is a list of the more serious side effects that may occur. If you experience any of these whilst taking this medicine, you should contact your doctor immediately.
As well as these more serious side effects, you could experience some of the less severe ones listed below. These are less of a cause for immediate concern. In fact, you may find that they pass over time as your treatment progresses and your body adjusts to the medicine. However, if you do find the effects lingering or worrying, then you still can contact your doctor for advice. They may be able to offer ways to reduce the unwanted effects.
If you experience any other side effects not listed here, then you can still contact your doctor. Again, they may be able to offer ways to reduce the effects.
Below you can find the typical doses of Peginesatide that are prescribed to patients suffering from anemia as a result of chronic kidney failure. Be aware that the exact doses your doctor prescribes you may differ greatly from what is listed below. This is because every patient is different and their needs may vary. It will also be based on other factors such as the other drugs you are currently taking and how frequently you should use the medicine. You should stick exactly to what your doctor has prescribed you and only alter this if told to do so by your medical professional.
You should aim to never miss a dose of his medicine as doing so will impact the effectiveness of the treatment. However, if you do miss a dose for any reason, then you should contact your doctor or pharmacist for details on how to proceed.
This injected is usually administered by a doctor. However, this medicine may sometimes also be used at home.If this is the case, then your doctor will first teach you how to administer the injection and how often. Before leaving the hospital or medical practice, ensure that you fully and properly understand how to give this medicine.
Upon receiving this medicine, you will find a Medication Guide. You should read this fully and address any questions you have to your doctor.
Peginesatide can come in one of three forms:
Peginesatide may be injected either into a vein or as a shot under the skin. You should follow your doctor's prescription regarding with form of injection is best.
Here is some further advice if you will be using this medicine yourself from home.
You may find that you do not use all of the medicine in each syringe or vial. You should still only use the single-use vials and syringes only once. Also, do not use any medicine if you notice that it has particles in it or has changed color.
It is possible that Peginesatide will interact with other medicines you are currently taking. It is often the case that your doctor will want to avoid these interactions, however, in other cases, they may be necessary. If your doctor wishes to avoid the interaction, then they may alter one or both of the interacting drugs. Alternatively, they may need to simply alter the doses of one or both medicines to limit an interaction that is necessary. Either way, you should inform your doctor of all drugs you are currently taking. Directly below is a list of drugs which are known to cause a major interaction if taken with Peginesatide.
The following drugs are known to cause a moderate interaction if taken at the same time as Peginesatide.
The following drugs are known to cause a minor interaction if taken at the same time as Peginesatide.
As well as drugs, it is possible that Peginesatide will interact with certain elements of your dietary intake. Your doctor may, therefore, advise you to make certain adjustments to how much or how frequently you consume certain things. This includes what you smoke, eat, and drink.for example, whilst taking this drug it may be necessary for you to smoke less tobacco or drink less alcohol.
Finally, other medical problems you have now or have had in the past may interact with Peginesatide. You should advise your doctor of your complete medical history. Below is a list of medical problems that are known to interact with this medicine.
Before prescribing you with this medicine, your doctor will first need to decide whether or not it is indeed suitable for you to take. They will weigh a number of different factors when making this decision. As a part of this process, they will need to be aware of any allergies you have.These can be allergies to food, animals, dyes, or preservatives.
As of writing, no efficacy and safety have been established for the use of Peginesatide in pediatric patients. This is because no suitable studies have taken place regarding the use of this drug on younger patients. Your doctor can advise you of any increased risks to your child of taking this medicine, and then decide whether any risks do outweigh the benefits it offers.
As of writing, the studies that have taken place in geriatric patients have not highlighted any issues that would make this drug less suitable for older patients to receive.
As of writing, it is unclear as to whether any studies have taken place on pregnant women taking this medicine. Your doctor is best placed to decide whether it is a safe and suitable drug for you to receive.
Similarly, there are no suitable studies for the use of this drug on breastfeeding women. Your doctor can inform you of any increased risk to you or your infant. Together, you can then weigh these risks against the benefits of receiving the medicine.
Your doctor will need to remain well-informed of your blood pressure whilst you are receiving this medicine. This may mean you need to test it yourself from home or it could mean you need to attend regular hospital visits. If you do notice any changes to your blood pressure at any time, you should inform your doctor straight away.
It is possible that Peginesatide will cause patients to experience some sort of severe allergic reaction. This includes problems like anaphylaxis. Anaphylaxis is life-threatening and requires you to seek emergency medical assistance. If you experience any of the following symptoms whilst taking Peginesatide, you should inform your doctor right away.
It is possible that this medicine will increase your chances of having blood clotting problems, a heart attack, congestive heart failure, or a stroke. If you notice any of the following symptoms, then you should inform your doctor immediately.
It is possible that this medicine will cause you to experience convulsions, especially whilst in the first few months of treating your condition. If you have any concerns about this, then you can discuss this with your doctor.
Many people suffering from kidney problems will need to go on a special diet. Similarly, those with high blood pressure, either as a result of the medicine or the kidney disease, will need a special diet for that as well. Even after anemia has been cured, some patients start eating more than before because they suddenly feel so much better. This may then cause your blood pressure or kidney disease to get worse. In order to avoid such issues occurring, you should closely follow the special diets given to you by your doctor. You should follow these even once you feel better.
As well as this medicine, your body will need vitamins and iron to make red blood cells. You may be told by your doctor to take vitamin or iron supplements. You should follow their instructions carefully if this is the case.
You should be careful to keep this medicine away from children at all times. Once you have finished your treatment, you should dispose of any remaining medicine in a safe and sensible way as instructed by your doctor or pharmacist. The same applies to any medicine that goes out of date. You should store your Peginesatide in a refrigerator, but do not allow it to freeze.
Any unused portions of your medicine that comes in multiple use vials may be stored in the refrigerator, but must be thrown away if not used after 28 days. You should store your medicine in the original packaging until it is time to use it. Be careful not to expose the medicine to light.
If you are suffering from anemia as a result of chronic kidney disease and are on dialysis, then Peginesatide may be a useful drug to help treat your condition. However, it can potentially interact with a range of drugs and other medical problems, so is only suitable for certain patients. In order to reduce the chance of unwanted interactions or side effects, your doctor will give you strict guidelines on how to use this medicine. They may also give you a special diet you should follow in order to best treat your condition. You should follow all guidance as closely as possible. If you have any other questions about your treatment or the use of Peginesatide, you should address these to your healthcare professional.