Sacrosidase (Oral)

Patients whose bodies do not naturally produce enough of the enzyme sucrase have found Sacrosidase to be an effective replacement; sucrase is an essential enzyme that helps the body to digest and absorb sucrose.

Overview

Sacrosidase is an effective medication for people whose bodies do not produce enough sucrase enzyme on its own. As this enzyme is key in the digestion and absorption of sucrose, it is important that sufficient levels are maintained in the body. Sacrosidase provides the necessary replacement and is commonly used to treat such conditions.

There is a high likelihood of allergic reaction in those taking Sacrosidase and the initial doses may be administered in your doctor's office in order to monitor your reaction. Your doctor may also require a skin test prior to beginning a course of treatment that includes Sacrosidase.

This medication comes in liquid form and is administered by adding it to milk, water, or baby formula. Do not use warm or hot beverages or fruit juices to deliver this medication as they may cause the Sacrosidase to break down thus making it less effective.

Your doctor will likely prescribe an alternative medication if you suffer from yeast, glycerin, or papain allergies. Patients who suffer from diabetes should take extreme caution when using this medication and alert their doctor if they experience any significant side effects.

This medication will affect your blood sugar as more sucrose is able to be absorbed and digested by your body. Your doctor may advise alterations to your diet, such as the reduction of starchy foods. Any dietary restriction should be followed as closely as possible, and your doctor should be informed of any difficulty you experience with sticking to the new eating plan.

Conditions Treated

  • CSID (Congenital Sucrase-Isomaltase Deficiency)

Type of Medicine

  • Gastrointestinal Agent

Side Effects

This medication has been reported to cause some side effects, and among these, there are several that will require medical advice or attention. If you suffer from any of the side effects that are listed below, it is always best practice to consult with the prescribing doctor to determine if further medical attention is warranted.

Unknown Incidence:

  • Pain in the chest area
  • Swelling in the areas of the face, throat, or tongue
  • Increased heart rate
  • Rapid breathing
  • Nervousness
  • Wheezing
  • Difficulty with breathing
  • Rash
  • Itching

There are other side effects that you may experience but will likely go away on their own. If you have any of the symptoms listed below, they should dissipate after a day or two and do not require further medical attention. However, these symptoms should not linger longer than a few days. If they do last or become worse, it is advised that you speak with your doctor.

Less Likely:

  • Abdominal or stomach pain
  • Confusion
  • Wrinkled skin
  • Inability to sleep
  • Dizziness
  • Thirst
  • Fainting
  • Sleeplessness
  • Increased thirst
  • Dry mouth
  • Nausea and vomiting
  • Lightheadedness
  • Sunken eyes
  • Headache
  • Trouble with sleeping
  • Decreased urination
  • Unusual tiredness or weakness
  • Diarrhea
  • Constipation

In addition to the symptoms listed above, others side effects may occur. If they do not go away on their own or become worse, it is advised that you discuss them with your doctor as they may require further medical attention. If you have any questions on how your body is reacting to the medication or are unsure if your side effects may be problematic, it is always best practice to consult with the prescribing physician.

Dosage

Sacrosidase comes in a liquid form and is administered by adding the solution to milk, baby formula, or water. It is important that the liquid that it is added to is not warm or hot. The heat of any warm beverages such as tea or hot cocoa will cause the medication to break down and become less effective. Do not mix the medication with fruit juices of any type as the acidity of such beverages can cause the Sacrosidase to break down and become less effective.

After checking the dosage guidelines below, you will add the recommended amount to two to four ounces of the cold beverage. Remember that fruit juices are not recommended, and it is advised that you use water, milk, or baby formula to administer Sacrosidase.

Sacrosidase will come with a measuring spoon or scoop that you can use to portion out your medication; the use of drops as a measurement is also possible. Whichever method you choose to implement, be sure to follow the dosage instructions provided by your doctor. Never take more Sacrosidase than what is advised by your doctor, and do not take it more often than what is prescribed.

If you use the measuring spoon or scoop to determine your dose, be sure to rinse and clean it thoroughly following each use.

It is recommended that this medication is taken with food, whether at a meal or accompanying a snack. Take one half of the dose prior to the meal and one half at the conclusion of eating.

Your physician may recommend changes to your diet while you are taking Sacrosidase, such as limiting the number of starches that you eat. If you are given an alternative diet to follow while taking Sacrosidase be sure to follow it as closely as possible and discuss any difficulties with your doctor.

The dosage guidelines below are the typical amounts used, however, be sure to follow any direction provided by your doctor as they may prescribe a different dosage level to you. If you have any questions regarding the dosage or how you should be taking Sacrosidase be sure to discuss with your doctor or pharmacist immediately.

Children who are prescribed Sacrosidase should follow the dosage amounts provided by their doctor or pediatrician as the amount of necessary medication can be determined on a case by case basis.

Older children, teenagers, and adults are recommended to take 2ml with each meal or snack throughout the day. If you are utilizing the drop method to measure your dose, this amount is equivalent to 56 drops.

Interactions

There are currently no known major drug interactions with Sacrosidase but it remains important that you discuss all medications that you are currently taking with your doctor. This includes both prescription and non-prescription strength medications. Also, let them know of any over the counter drugs that you are taking including herbal remedies and vitamin and mineral supplements. If you change the dosage or frequency of any medications while taking Sacrosidase be sure to inform your doctor.

While there are not any reported incidences of major drug interactions in patients who are taking Sacrosidase, there are other medical conditions that can affect how your body reacts to this medication.

  • Diabetes - patients that suffer from this condition need to exercise caution when using Sacrosidase as it has been reported to worsen the condition in some cases.
  • Glycerin - if you have an allergy to this substance be sure to inform your doctor prior to beginning your Sacrosidase course of treatment. They may determine that an alternative medicine is more appropriate.
  • Papain - an allergy to Papain can cause interference in patients taking Sacrosidase and it should be avoided.
  • Yeast Allergy - this ailment can cause unwanted and potentially dangerous effects when Sacrosidase is taken. Do not take Sacrosidase if you have a yeast allergy.

Warnings

This drug has been known to cause serious allergic reactions. In fact, your doctor may require that the first and second doses be administered in their office or at another medical provider location. If you experience a rash or itching or swelling of the face, throat, or tongue you should immediately report such symptoms to your doctor. Follow the same protocol if it becomes difficult for you to breathe or you begin to experience chest pain.

Because of this possibility of an allergic reaction, your doctor may order a skin test prior to prescribing this medication. If you know of anyone in your immediate family who has had an allergic reaction to Sacrosidase be sure to inform your doctor of this information prior to taking this medication.

The impact of the greater level of sucrase absorption can also affect your blood sugar in a significant way. If you suffer from diabetes or low blood sugar, be sure to thoroughly discuss these conditions with your doctor prior to starting your Sacrosidase course of treatment.

Storage

Sacrosidase comes in a liquid form that requires refrigeration. Do not freeze this medication. Keep the liquid in the original packaging and do not transfer to another container.

Keep this and all medications out of the reach of children.

If, at the end of your course of treatment, you have excess medication discuss with your doctor or pharmacist the best option for proper disposal. Do not keep any unused or expired medications.

Summary

Sacrosidase is an effective antidote for people whose body does not produce the sucrase enzyme at sufficient levels. Patients who are prescribed Sacrosidase should follow the instructions of their doctor very carefully and advise them of any changes or concerns that they experience when taking this medication.

There is a possibility of allergic reaction to this medication and your doctor may administer the first and second doses at their office in order to monitor your reaction. They may also administer a skin test prior to prescribing this medication. If you are aware of anyone in your immediate family who has had an allergic reaction to Sacrosidase it is important that you share such information with your physician.

This medication will alter your blood sugar levels as more sucrose is absorbed and digested into the body. If your doctor advises a modified diet such as one low in starch, it is important that you follow their recommendations as closely as possible.

Do not add this medication to warm beverages or fruit juices as those substances can break down the Sacrosidase and make it less effective. It is recommended that Sacrosidase is taken by adding it to milk, water, or baby formula.

If you experience an allergic reaction while taking this medication it is important that you notify your doctor immediately.

 

Resources
Last Reviewed:
January 30, 2018
Last Updated:
April 05, 2018
Content Source: