Technetium Tc 99m Tetrofosmin (Injection)

Technetium (99mTc) tetrofosmin is radioactive and potentially toxic, so is only ever administered by a medical professional, qualified in nuclear medicine.

Overview

Technetium (99mTc) tetrofosmin is from the radiopharmaceutical family of medication injected into a patient's body prior to a heart imaging test. A radiopharmaceutical is a radioactive imaging agent, often utilised to diagnose and treat specific diseases or conditions, or to allow a better study of various organs in the patient's body various organs.

A technetium (99mTc) tetrofosmin injection allows your doctor to see clear images of the heart under examination. It enables your doctor to check how well your heart is working under various levels of stress, including when you are at rest and during exercise. It can also allow your doctor to evaluate you appropriately, should he believe you have possible heart failure, or diseases affected the coronary arteries.

Technetium (99mTc) tetrofosmin should only ever be administered by a medical professional, specialized in the administration of nuclear medicine, or under their immediate supervision.

Technetium (99mTc) tetrofosmin is distributed in dosage forms as follows:

  • kit

Conditions Treated

  • administered prior to a heart imaging test

Type of Medicine

  • radiopharmaceutical

Side Effects

Alongside its expected and desired effects, an injection of technetium (99mTc) tetrofosmin might cause some less desirable side effects. While there is no guarantee that all (or even some) of the effects will necessarily occur, should any of them do so, you may need to seek medical attention or treatment.

Should any of these following side effects exhibit themselves following your injection of technetium (99mTc) tetrofosmin, you should consult your prescribing doctor immediately.

  • pain in back, arm, or jaw
  • discomfort or pain in the chest
  • heaviness or tightness in the chest
  • irregular or fast heartbeat
  • sweating
  • nausea
  • difficulty breathing
  • blurred vision
  • feelings of confusion
  • feelings of faintness, dizziness, or light-headedness whilst suddenly standing up from a seated or prone position
  • pounding, racing, irregular, or fast pulse or heartbeat
  • unusual weakness or tiredness
  • coughing
  • problems swallowing
  • itching, skin rash, or hives
  • swelling or puffiness around the eyes, tongue, lips, eyelids, or face

While the above-listed side effects might require medical treatment, there are certain side effects that might occur which tend not to need the immediate attention of a doctor. Such effects may disappear during your course of treatment as the body acclimatizes itself to the medication. Also, your doctor might offer advice that will reduce or prevent a number of the possible side effects. Should any of these effects present themselves in a manner that becomes bothersome, consult with your doctor.

  • stomach or abdominal pain
  • change to your sense of taste or smell
  • feeling of hotness or warmth
  • redness to the upper chest, arms, neck, or face

There may be different side effects which present themselves in certain patients. Should you spot any unusual or unwanted effects following your injection of technetium (99mTc) tetrofosmin be sure to consult your doctor.

Dosage

Technetium (99mTc) tetrofosmin should only ever be administered by a qualified medical professional, trained in the administration of nuclear medicine. As such, the dosage you will receive will be very carefully calculated by the administering health care professional.

Technetium (99mTc) tetrofosmin is administered via a needle inserted into a vein.

You will have to urinate immediately and often following your injection of technetium (99mTc) tetrofosmin , and so you should drink plenty of non-caffeine liquids both before and after your heart test so that your body will be able to expel sufficient urine. Continue to do so as advised by your examining doctor.

Major Drug Interactions

Some medicines should never be used with one another under any circumstances. In other situations, two different forms of medication might be utilised at the same time, even though there is a risk of a known interaction occurring between the two of them. In cases like these, your examining doctor may wish to amend the dose of Technetium (99mTc) tetrofosmin you receive, or may offer advice on other precautions you can take to lessen the effects of the interaction. Be sure to inform your doctor if you happen to be currently taking another kind of medicine, be it one prescribed by your doctor, or a remedy purchased from your pharmacist.

Certain types of medication ought not to be taken at the same time (or close to the same time) as eating particular foods since, due to the risk of an unwanted interaction occurring. Be sure to discuss these things with your doctor, prior to examination, the possible risks of combining technetium (99mTc) tetrofosmin with tobacco products, alcohol, or food.

Warnings

When deciding to use a medicine like technetium (99mTc) tetrofosmin, you must weigh the risks of its administration against the good that it will do. This should be a decision reached between you and your examining doctor, following a full consultation. For technetium (99mTc) tetrofosmin you should consider the following:

It is vital that you inform your doctor, should you have previously exhibited any allergic or otherwise unusual reaction to technetium (99mTc) tetrofosmin, or any other kind of medication, in the past. You should also advise your examining doctor if you suffer from other kinds of allergies, such as an allergic reaction to animals, foods, dyes, or preservatives.

Appropriate studies have yet to be performed regarding any relationship between age and the effects of technetium (99mTc) tetrofosmin and age amongst children. As such, the safety and efficacy of technetium (99mTc) tetrofosmin among the pediatric population have yet to be established.

Such appropriate studies as have been performed to date have yet to demonstrate any specific problems that might inhibit the effectiveness of technetium (99mTc) tetrofosmin injection as a treatment among the elderly.

Animal studies conducted with technetium (99mTc) tetrofosmin have indicated that there is an adverse affect on the fetus in the womb, though there have yet to be adequate studies on the matter amongst pregnant women

Appropriate studies in women breastfeeding have demonstrated a link between using technetium (99mTc) tetrofosmin and harmful effects in infants. If you are breastfeeding at the time of your injection with technetium (99mTc) tetrofosmin then you should either seek an alternative medication, which will allow you to continue breastfeeding, or you should shop breastfeeding whilst utilising this medication. You should speak to your doctor about any concerns you have regarding breastfeeding.

It is essential that you have regular consultations with your doctor whilst using technetium (99mTc) tetrofosmin. This allows your examining doctor the opportunity to determine that your medication is acting as it should, and whether or not you ought to continue with this course of treatment.

Technetium (99mTc) tetrofosmin has been known to prompt a dangerous allergic reaction, such as anaphylaxis. This can be a life-threatening reaction, and one that demands immediate attention from a medical professional. You should consult your examining doctor as a matter of the utmost urgency should develop any of the symptoms of anaphylaxis following your injection of technetium (99mTc) tetrofosmin. These include chest pains, difficulty with breathing, a rash, swelling around the throat, tongue, nose and face, and persistent itching.

When injected with technetium (99mTc) tetrofosmin, it is required to expose you to radiation. If the thought of this concerns you, you need to discuss it with your examining doctor. Be sure to follow any advice and directions offered by your doctor that will lessen the risk of being exposed to radiation.

You must ensure that any doctor, dentist, or other healthcare professional involved in treating you is aware of your usage of technetium (99mTc) tetrofosmin, as it has been demonstrated that it can affect the outcome and results of some specific medical tests and procedures.

There are certain medical conditions, the presence which may affect the administration or efficacy of technetium (99mTc) tetrofosmin. Be sure to inform your examining doctor, or other healthcare professional if you suffer from any other medical complaint, but specifically any listed below:

  • bronchoconstriction, or any other breathing problems
  • hypotension, or low blood pressure
  • a history of strokes

If suffering from any of the above conditions, technetium (99mTc) tetrofosmin should be used with caution, as it might make these ailments worse.

Storage

Technetium (99mTc) tetrofosmin should only ever be administered by a qualified medical professional, with specialized training in the field of nuclear medicine. As such, there are no circumstances in which you will be expected to store technetium (99mTc) tetrofosmin at your own home.

Summary

Technetium (99mTc) tetrofosmin is used during nuclear medicine cardiac imaging in order to diagnose various medical conditions relating to the heart, including reversible ischemia and infarcted tissue. It is a radioactive chemical and should only ever be administered by a suitably qualified medical professional, trained in the application of nuclear medicine. It allows for a better study of a patient's internal organs, specifically the heart, and is an essential treatment route for examination.

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Last Reviewed:
December 23, 2017
Last Updated:
December 22, 2017
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