Tedizolid (Oral)

Tedizolid, also known by the brand name Sivextro, is taken by people who suffer from serious bacterial infections, helping to stop the growth and alleviate symptoms.


Tedizolid is a useful medication taken by people who suffer from serious bacterial infections. It is effective in helping to stop the growth of harmful bacteria and thus alleviate symptoms. In order to embark on a course of treatment using Tedizolid, you should first receive a prescription from your doctor.

There are a number of potential side effects associated with taking Tedizolid (brand name Sivextro), and it is for your own safety that you are made well aware of all such risks beforehand. As well as this, and as is discussed below, Tedizolid can have a number of interactions with other foods and drugs you may be taking. Your medical professional can best advise you if this oral form of Tedizolid is best for you.

Condition(s) treated

  • Skin infections which have been caused by Staphylococcus Aureus bacteria
  • Skin infections which have been caused by Streptococcus Pyogenes bacteria
  • Skin infections which have been caused by Streptococcus Agalactiae bacteria
  • More complicated skin infections which have been caused by Enterococcus Faecalis bacteria
  • More complicated skin infections which have been caused by other bacteria.

Type of medicine

  • Tablet

Side Effects

Below you can find a list of most of the possible side effects caused by taking Tedizolid. Do be aware that it is very hard to know which side effects you may suffer from, if any at all. However, if you do experience any of the following, then immediately stop taking Tedizolid and consult your doctor:

  • Difficulty swallowing or breathing
  • Breathing with exertion
  • Unexpected bleeding or bruising
  • Chills across the body
  • Dizziness
  • Irregular or pounding heartbeat
  • Tenderness of the stomach or abdominals
  • Back pain
  • Chest tightness
  • Unexpected weakness or tiredness
  • Bloody or watery diarrhea
  • Vision blurred
  • Nausea and vomiting
  • Nervousness
  • Pale skin
  • Tightness in the chest
  • Fever
  • Headaches
  • Hives, welts, itching, or skin rash
  • Hoarseness of the voice
  • Joint pain, stiffness, or swelling
  • Ears are pounding
  • Skin redness
  • Severe abdominal or stomach cramps/pain
  • Fast or slow heartbeat
  • Swelling of the lips, hands, eyelids, face or feet

You may also suffer from a number of side effects which, though slightly uncomfortable, will not mean you should stop taking Tedizolid. As your course of treatment is ongoing, these side effects may crop up but then disappear. If they are worrying you at all, then visit your doctor. They may suggest you stop altogether or may be able to alter the dosage to limit or offset the side effects.

  • Painful, burning, tingling or numbness sensations
  • Weakness in the arms, hands, legs, or feet
  • Awkwardness or unsteadiness
  • Diarrhoea

Less common or rare side effects:

  • Changes in vision
  • Redness of the neck, arms, face or upper chest
  • Visions of floating spots before the eyes
  • White patches on your tongue or mouth
  • Sore tongue or mouth
  • Blurred vision
  • Crawling, itching, prickling or "pins and needles" feelings
  • Random feelings of warmth
  • Difficulty sleeping

If you experience anything not found on this list but still believe it is a side effect as a result of taking Tedizolid, then contact your doctor straight away.


Here are some common dosage allowances as prescribed by medical professionals:

  • Adults: To treat skin infections take 200mg once a day
  • Children: To treat skin infections, first consult with your doctor for exact amounts.

However, do be aware that you should only take what has been prescribed to you by your doctor. If the amount prescribed is lower than that above, then still stick to the doctor's dosage as there may be other factors which affect how much you can have. The necessary dosage as prescribed by your doctor should also be available on the labeling following the prescription being issued.

If you miss a dose one day, but then remember, take it as soon as possible. However, this is not the case if you are almost ready to take the next scheduled dose. You should not take 2 doses within 8 hours of each other, so simply skip the missed dose if this is the case. Afterwards, continue with your schedule as normal.

Tedizolid is best taken on a regular schedule, and it doesn't necessarily matter whether or not you have recently eaten, as it can be taken on an empty or full stomach. Once you find that your symptoms are clearing up, don't be tempted to stop taking Tedizolid. Instead, you should follow the full course through as recommended by your doctor. Failure to do so could lead to the bacterial infection coming back and replacing the improvements that have been shown.

This is, of course, as long as you don't start experiencing any of the worrying side effects listed above.


As with all forms of medication, there are chances where two separate prescriptions may interact with one another. This will depend on a number of factors, not limited to all the drugs you currently take, as well as your personal health and situation. For this reason, when being prescribed Tedizolid, be sure to tell your doctor about any other medication you take.

It may be the case that, even if two drugs will cause an interaction, it will be mild and still beneficial to proceed with both. Similarly, your doctor may advise against Tedizolid and instead recommend a different solution which would be better for you. If you currently take a Cholera Vaccine, then be sure to make your doctor well aware of this, as it is the most common vaccine known to cause interactions with Tedizolid.

Other than reacting to certain drugs, there is a chance that Tedizolid may react with certain foods that are in your diet. It could also be affected by certain intakes of alcohol or tobacco. Therefore, as well as what drugs you take, be sure to make your doctor fully aware of your drinking, eating and smoking habits. They can then advise whether or not you need to adjust your diet to compliment the addition of Tedizolid.


  • Be aware that Tedizolid will not be suitable for viral infections like the flu.
  • As with any form of antibiotic, if you are to abuse or misuse it, then its effectiveness will be decreased.
  • There are a number of side effects (as listed above) which can occur whilst taking Tedizolid, so you will need to have regular meetings with your doctor to check your progress. There, they can ascertain whether or not the course of treatment is progressing well, and if there are any unwanted effects that need dealing with.
  • If your symptoms progress at any time to a point where you feel unsure or uncomfortable, then, rather than waiting until your next assessment, seek your doctor's help immediately.
  • Diarrhea is a possible side effect of taking Tedizolid and can occur up to 2 months after you stop taking the medication. You should not take any further medication to treat this diarrhea without first consulting with your doctor. If diarrhea gets worse or is not passing, then again, seek medical advice.
  • If you are already suffering from diarrhea, then make your doctor aware of this. As stated, Tedizolid can cause much more severe cases of this.
  • Be aware that there have been no in-depth studies into the effects of taking Tedizolid for breastfeeding women. This is not to say that there are any major risks. Instead, you and your medical professionals should weigh the potential benefits and risks of taking Tedizolid to check it is worth taking.
  • Similarly, there are very few animal or human trials that have taken place regarding Tedizolid for pregnant women. So again, you will need to discuss this on a case-by-case basis with your doctor to ensure it is suitable for you to proceed.
  • There has been little trials into the effects or usefulness of Tedizolid on pediatric patients. However, it is recommended that children will have a different prescribed daily amount to that of adults, which will be stated upon prescription.


When storing Tedizolid, be sure to keep it away from direct sunlight and away from heat. Instead, it should be kept in a sealed container and stored at room temperature. Do not keep in a location where it may be prone to freezing, or where children can access it. If you go to use your Tedizolid and find that it is no longer in date, then do not use and dispose of it immediately. Similarly, if you are no longer using Tedizolid as you do not require it, then also dispose of it. If you are unsure how to safely and correctly dispose of the medication, then consult your doctor first.


Tedizolid is a potentially very beneficial medication used in the treatment of a number of worrying and serious bacterial skin infections. However, as with most medications, there are a number of risks and precautions you should take when using it. Taking too high dosages, or failing to regularly take the daily dose, will greatly alter the effects and the benefits you receive. Before embarking on a course of Tedizolid, you should first receive a prescription from your doctor.

You should be honest and upfront with them about any other drugs you take, as well as your dietary intake. This is to advise whether or not Tedizolid is the best medicine for you. With certain people on other medication, Tedizolid can pose a number of interactions (listed above) which are potentially harmful or at least worrying. If you have ever used Tedizolid in the past then this doesn't necessarily mean it is the best course of treatment to follow again, so do speak to a medical professional. As with all things regarding your health and wellbeing, exercise care and responsibility.


Last Reviewed:
December 24, 2017
Last Updated:
April 03, 2018
Content Source: