Terbinafine (Topical)

Terbinafine helps treat skin infections like athlete's foot, ringworm infections, and jock itch, and is available under these brand names: LamISIL and LamISIL AT.


Although many kinds of fungi live innocuously on the skin, some may cause skin diseases. The tinea fungi group is the most common fungi that causes skin infections. For example, athlete's foot (aka tinea pedis) is a common infection of the feet and toes, and fungal groin infection (aka tinea cruris) is a fungal disease which attacks the groin area. Fungal or yeast infections can affect other body parts as well.

Terbinafine is a topical antifungal medicine which is used on the skin as a solution, spray, cream, or gel. It works by eliminating the fungus that causes skin infections. Although Terbinafine is a prescription medicine, you can also get some preparations over the counter at pharmacies as well as other retail outlets.

If your fungal disease is extensive, or it's in a difficult to treat place (e.g. an infection in the nail), it may need treatment with pills prescribed by a physician.

Conditions treated

Type of medicine

  • Antifungal

Side effects

Itching, burning, or irritation can occur at the site of application. If these effects persist or get worse, notify your pharmacist and doctor right away.

If your physician has instructed you to use Terbinafine, keep in mind that he/she has concluded that the medicine is more useful to you than risky. The majority of people using Terbinafine don't suffer serious side effects.

Notify your doctor promptly if you notice any of these rare but severe side effects: oozing/swelling/blistering at the application area.

This drug rarely causes an extreme allergic reaction. However, seek medical attention promptly if you suffer any of these symptoms of a severe allergic reaction: severe dizziness, troubled breathing, rash, and swelling or itching of the throat/tongue/face.

Stop using Terbinafine and contact your physician promptly if you have one or some of these serious side effects: severe blistering, itching, peeling, redness, irritation of skin, or dryness.

Less serious effects are much more likely, but you may not have any.

The above list of Terbinafine side effects is in no way complete. If you have other different side effects, notify your healthcare provider right away.

For medical advice regarding side effects, call your doctor. You can notify the FDA about Terbinafine side effects at 1-800-FDA-1088.


Use Terbinafine only on the skin. Wash and dry the area affected thoroughly. Apply enough Terbinafine to make the skin around and on the area affected wet, usually one or two times a day as instructed by your doctor or on the product pack.

If you need the information on the package explained further, consult your pharmacist and/or physician. If you've been prescribed Terbinafine, then use it as instructed. After applying the medication, wash your hands unless the part being treated includes your hands. Don't bandage, cover, or wrap the area unless your doctor orders you to do so.

Don't use this medication in your eyes, mouth, nose, or vagina. If the medication gets into those areas, please flush with lots of water.

Don't use Terbinafine on the nails or scalp unless otherwise instructed by your physician.

Don't use the spray variety of Terbinafine on your face.

The length of treatment and dosage depends on the kind of condition being treated.

If you're applying gel or cream, apply a thin coat one or two times daily and then gently rub it in. You'll need to apply it on a regular basis for a couple of weeks. Once all symptoms of your disease have disappeared, continue using Terbinafine for two or three more days to prevent the recurrence of your infection.

If you're using a spray, use it one time daily for 1 week and make sure that the spray covers all of the affected area.

If you're applying a solution, use it just once a day. At the same time, treat your feet by applying a layer of solution, ensuring that you use it between the toes, on the sides of the feet, and on soles of the feet. This solution will then dry to create a film. Don't clean your feet for 1 day after applying the solution.

Don't apply the medication more frequently or use it longer than prescribed. This may heighten the chances of suffering side effects.

Use Terbinafine regularly to take full advantage of its benefits. To help you recall when to use, use it at similar intervals every day.

Continue using Terbinafine as instructed until you're through with the full treatment schedule, even if your symptoms go away after a matter of days. Don't stop using this medication too early or your infection may recur.

Your condition can continue to get better after stopping Terbinafine as directed. Notify your physician if your condition deteriorates or doesn't get better after a week of treatment.


When you're taking Terbinafine, it's very important that your doctor or other healthcare provider know if you're using any of the drugs listed below. These interactions have been picked depending on their potential impact and aren't necessarily comprehensive.

Using Terbinafine with any of these medications is normally not recommended. However, you may take Terbinafine with some of these medicines in some instances. If your doctor prescribes Terbinafine with any of these medicines, they may adjust the dose or the frequency of taking either or both medications.

  • Nebivolol
  • Eliglustat
  • Brexpiprazole
  • Fluoxetine
  • Doxorubicin Hydrochloride Liposome
  • Clozapine
  • Donepezil
  • Doxorubicin
  • Metoprolol

Using this medication with the following medications can increase the risk of some effects, but taking both medications can be your best option of treatment. If your physician prescribes both medications, he or she may adjust your dose or how frequently you take one or both drugs.

  • Warfarin
  • Nortriptyline
  • Cyclosporine

It's highly unlikely that other medicines you inject or take orally will affect topically applied Terbinafine.


If you have an allergy to Terbinafine, let your pharmacist or doctor know. Let him/her also know if you have an allergy to allylamine antifungals such as naftifine, or if you've got other allergies. There may be inactive ingredients in Terbinafine, which may lead to allergies or other problems. Have a chat your with pharmacist to get more information.

If you're suffering from any medical conditions, consult with your pharmacist and other healthcare givers before using Terbinafine.

During pregnancy, Terbinafine should only be taken when it's very necessary. Talk about its pros and cons with your doctor.

Other versions of Terbinafine can get into human milk if taken orally. It's not clear whether topical Terbinafine gets into breast milk. Breastfeeding mums should not take this medication. If you're using Terbinafine, talk to your doctor first before breastfeeding.

Terbinafine is to be used only on your skin. If you or someone else accidentally swallows this drug, go to the casualty or emergency room of your nearest health facility. Bring the container along, even if it's empty.

Only you should use this medicine. Never allow someone else or other people to take it even if their problem seems similar to yours.


Store this medication at room temperature (i.e. 20-25 degrees C).

Protect Terbinafine from heat and light, and don't refrigerate Terbinafine.

Make sure your children and pets don't reach this drug. Don't pour Terbinafine into a drain or flush it down your toilet unless your healthcare giver tells you to.

When this medication expires or you no longer need it, properly discard it. If you don't know how to safely discard of this drug, get in touch with your pharmacist or waste disposal firm.


Remember to carefully wash your hands after using this drug as this will prevent your infection from getting to other areas of your body. In addition, use a different towel until your infection goes away.

Fungal infections often develop in moist, warm areas of your body. After showering or bathing, make sure to dry your entire skin well, especially areas like between your toes and skin folds.

Just so you know, athlete's foot usually goes away within 7 days of treatment while infections of the groin area clear up within 14 days of treatment. If you don't see any improvement after these periods, be sure to arrange an appointment with your doctor to get further medical advice.

Don't keep medicines that are out of date or unwanted. Dispose of them safely or hand them over to your nearest pharmacy for disposal.

It you've got several questions about Terbinafine, ask your pharmacist.

Honor all routine lab and medical appointments. Make sure to put on well-ventilated, fitting shoes when treating athlete's foot. In addition, change your socks and shoes at least once every day. If you're treating pityriasis, you may not have your usual skin color back right away. It may take months after completing treatment for your real skin color to return.

Last Reviewed:
December 24, 2017
Last Updated:
April 05, 2018
Content Source: