Tranexamic Acid (Intravenous)

Tranexamic Acid is a medication that helps reduce or prevent bleeding in certain conditions, including heavy menstrual bleeding, dental surgery in patients with inherited blood clotting disorders, nose bleeds, bleeding in the eye, and cervical cancer.


Tranexamic Acid refers to a man-made variety of a protein (amino acid) known as lysine. It prevents the breakdown of blood clots by the body's enzymes.

Cyklokapron helps prevent bleeding in hemophilia patients who need their tooth pulled. This medication is administered just before the procedure, and every day for up to eight days afterwards.

Tranexamic acid can also be taken for other purposes not covered by this piece.

You shouldn't take Tranexamic acid if you have allergies to it, or:

  • You have problems with your eyes' blood vessels
  • You have had stroke previously
  • You have color blindness
  • You've previously bled in your brain
  • You've had a blood clot recently
  • You are prone to forming blood clots
  • You have active blood clotting disorders, such as cerebral thrombosis, pulmonary embolism, and deep vein thrombosis
  • You have blood in your urine

To ensure Tranexamic is safe for your use, inform you physician if you have:

  • Leukemia
  • Kidney disease
  • Kidney or bladder infection

This medicine may damage your eyesight. Be cautious if you drive a vehicle or do any activity that requires you to see clearly.

Some Tranexamic Acid side effects include dizziness, lightheadedness, nausea, rash or mild itching, diarrhea, and vomiting.

Conditions treated

  • Bleeding due to abnormally long/heavy periods
  • Bleeding after an operation
  • Bleeding due to breakdown of fibrin required for clotting

Type of medicine

  • Antifibrinolytic agent

Side effects

Many drugs do bring on side effects. The side effects could be severe or mild, permanent or temporary. The following Tranexamic Acid side effects aren't experienced by everybody who uses this medicine. If these side effects bother you, be sure to discuss the pros and cons of this medicine with your doctor.

Call your doctor/healthcare provider immediately if you suffer the following effects.


  • Chest pain
  • Anxiety
  • Changes in vision
  • Blurred vision
  • Cough
  • Lightheadedness or dizziness
  • Fast heartbeat
  • Confusion
  • Fainting
  • Greatly decreased or increased amount of urine or frequency of urination
  • Increased thirst
  • Vomiting or nausea
  • Loss of appetite
  • Numbness of hands
  • Pain, swelling, or redness in the leg or arm
  • Troubled breathing or sudden shortness of breath

Frequency not known:

  • Seizures or convulsions
  • Trouble seeing
  • Sweating
  • Unusual weakness/tiredness
  • Faintness, lightheadedness, or dizziness when suddenly getting up
  • Puffiness/swelling of eyelids, around eyes, lips, tongue, or face

Some Tranexamic side effects that normally don't require treatment may occur. They may disappear as you adjust to the medication during treatment. In addition, your healthcare giver can help you prevent or ease some of the effects.

Check with your healthcare giver right away if you have any of these side effects and they're bothersome or persistent.

More common:

  • Chills or fever
  • Back or joint pain
  • Runny/stuffy nose
  • Difficulty with moving
  • Severe, throbbing headache
  • Stomach/abdominal pain, tenderness, or discomfort
  • Muscle stiffness/pain

Frequency unknown:

  • Diarrhea
  • Vomiting
  • Nausea
  • Giddiness
  • Hives, redness/itching of skin

Get emergency assistance promptly if any of these overdose symptoms occur:

  • Diarrhea
  • Rash
  • Mental depression
  • Muscle twitching/jerking
  • Unusually vivid dreams or nightmares
  • Rhythmic movement of muscles

Possible serious Tranexamic acid side effects include:

  • Cerebral thrombosis
  • Allergic dermatitis
  • Convulsions
  • Visual impairment
  • Pulmonary embolism

Some people may suffer side effects that are different from the ones listed above. Consult your healthcare provider if you suffer any side effect that bothers you while you're using Tranexamic Acid.


Follow all the instructions on the label of the prescription. Don't use Cyklokapron in smaller or larger quantities or for a longer period than recommended.

Cyklokapron is injected via an IV into a vein just prior to your tooth being pulled. You may have to keep using Cyklokapron for up to eight days afterwards.

Your doctor may show you how an IV is used at home. Never self-inject Cyklokapron before you've fully learnt how to administer the injection and discard used IV tubing, needles, as well as other items used in injecting the medicine.

To ensure Cyklokapron isn't causing adverse effects, you may need to have your vision tested while you're using this medication. Follow your physician's directions.

If you miss your Cyklokapron dose, call your physician for directions.

If you overdose on Cyklokapron, seek emergency treatment or contact your poison control agency at 1-800-222-1222.


While certain drugs shouldn't be taken together in any way, in some cases two separate drugs can be taken together no matter if an interaction may occur. In such cases, your doctor can alter your dose, or give you other precautions.

When you're receiving Cyklokapron, it's vitally important to notify your healthcare provider if you're using any of the medications below.

Taking intravenous Tranexamic acid with any of these drugs isn't recommended. Your healthcare give may opt to treat you using Cyklokapron or change other medicines you use.

  • Rilpivirine
  • Desmopressin
  • Artemether
  • Live Rotavirus Vaccine
  • Praziquantel

Using Cyklokapron with any of these drugs is normally not advisable, but may be necessary in certain cases. If your doctor prescribes both drugs, he or she can change your dose or how frequently you take both or either medication.

  • Alcuronium
  • Amtolmetin Guacil
  • Atracurium
  • Bemiparin
  • Aceclofenac
  • Bosutinib
  • Boceprevir
  • Bromfenac
  • Bufexamac
  • Bupropion
  • Cidofovir
  • Ceritinib
  • Choline Salicylate
  • Cisatracurium
  • Clonixin
  • Celecoxib
  • Aldesleukin
  • Colistimethate Sodium
  • Clarithromycin
  • Conivaptan
  • Daclatasvir
  • Dasatinib
  • Dexibuprofen
  • Desogestrel
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dienogest
  • Dipyrone
  • Darunavir
  • Cobicistat
  • Doxacurium
  • Doxorubicin
  • Drospirenone
  • Doxorubicin Hydrochloride Liposome
  • Efavirenz
  • Elvitegravir
  • Ethacrynic Acid
  • Enzalutamide
  • Estradiol
  • Ethinyl Estradiol
  • Ethynodiol
  • Etodolac
  • Etofenamate
  • Etonogestrel
  • Flurbiprofen
  • Etravirine
  • Fepradinol
  • Droxicam
  • Fosamprenavir
  • Fenoprofen
  • Flufenamic Acid
  • Feprazone
  • Floctafenine
  • Vortioxetine
  • Fazadinium
  • Foscarnet
  • Gallamine
  • Felbinac
  • Etoricoxib
  • Furosemide
  • Hexafluorenium
  • Gestodene
  • Idelalisib
  • Indomethacin
  • Ixabepilone
  • Ketoprofen
  • Ketorolac
  • Lornoxicam
  • Lumiracoxib
  • Loxoprofen
  • Mefenamic Acid
  • Meclofenamate
  • Mestranol
  • Decamethonium
  • Metocurine
  • Meloxicam
  • Morniflumate
  • Mivacurium
  • Nadroparin
  • Nabumetone
  • Nepafenac
  • Naproxen
  • Nevirapine
  • Nilotinib
  • Nifedipine
  • Nimesulide Beta Cyclodextrin
  • Niflumic Acid
  • Norethindrone
  • Nimodipine
  • Levonorgestrel
  • Norgestrel
  • Nimesulide
  • Oxaprozin
  • Norgestimate
  • Pancuronium
  • Olaparib
  • Phenylbutazone
  • Oxyphenbutazone
  • Parecoxib
  • Piperaquine
  • Pipecuronium
  • Pixantrone
  • Pranoprofen
  • Piketoprofen
  • Proglumetacin
  • Piroxicam
  • Ritonavir
  • Propyphenazone
  • Rofecoxib
  • Proquazone
  • Rapacuronium
  • Salsalate
  • Ibuprofen
  • Sorafenib
  • Sodium Salicylate
  • Romidepsin
  • Sunitinib
  • Salicylic Acid
  • Telaprevir
  • Saquinavir
  • Sulindac
  • Tiaprofenic Acid
  • Tacrolimus
  • Tolfenamic Acid
  • Tenoxicam
  • Tubocurarine
  • Thalidomide
  • Valdecoxib
  • Ticagrelor
  • Vecuronium
  • Tolmetin
  • Rocuronium
  • Ulipristal
  • Lapatinib
  • Vincristine Sulfate Liposome

Taking Cyklokapron with any of these medications can increase the risk of some side effects, but taking both drugs may your best option for treatment. If your doctor prescribes both drugs, he/she may change your frequency of using either or both drugs or change your dose.

  • Alcuronium
  • Aprepitant
  • Aspirin
  • Atracurium
  • Bumetanide
  • Caspofungin
  • Fluindione
  • Fosaprepitant
  • Fosphenytoin
  • Gallamine
  • Hexafluorenium
  • Licorice
  • Metocurine
  • Netupitant
  • Ospemifene
  • Pancuronium
  • Phenobarbital
  • Phenytoin
  • Rifampin
  • Rifapentine
  • Saiboku-To
  • Vecuronium
  • Warfarin
  • Aminoglutethimide


Before you start taking any medication, let your healthcare giver know of any allergies or medical disorders you have, any drugs you're using, whether you're breastfeeding or pregnant, as well as any other important information about your health. The following factors can affect how you use Tranexamic Acid.

Birth control

Hormonal birth control methods like birth control pills up the risk of having blood clots. Using Tranexamic Acid alongside birth control can increase your risk for blood clots. If you're using any hormonal birth control, talk to your doctor about how Cyklokapron may impact your medical problem, how your medical problem may affect the dosage and effectiveness of Cyklokapron, and whether you may need any special monitoring.

Blood clots

This medication ups the risk of blood clots forming, causing reduced blood flow to the organs or other areas of the body.

If you're prone to clotting, your risk of suffering blood-clot related issues could be higher. These issues may include a stroke, heart attack, or clots in your leg's deep veins. Talk to your doctor about how Tranexamic Acid may impact your medical problem, how your medical problem may affect the effectiveness and dosage of Tranexamic Acid, and whether you will need any sort of special monitoring.

Drowsiness/reduced alertness

Tranexamic Acid can cause dizziness or drowsiness, impacting your ability to operate machines or drive. Don't do any hazardous jobs until you've established how Tranexamic Acid affects you.

Vision changes

Regular Cyklokapron use can cause vision changes, including changed color recognition, blurred vision, or change in field of vision. Contact your doctor right away if you notice anything unusual about your vision while taking Cyklokapron.


This medicine shouldn't be taken during pregnancy unless it is absolutely necessary. If you get pregnant while taking Tranexamic Acid, contact your doctor as soon as possible.


This medicine gets into human milk in very little amounts. If you're taking Tranexamic Acid and are breastfeeding, it may harm your baby. Consult your doctor to find out whether it's wise to continue breastfeeding.


The efficacy and safety of taking Cyklokapron to treat heavy monthly periods in teenage girls hasn't been established.


Keep Tranexamic Acid solution in a cupboard, far away from direct sunlight, moisture and heat. This medicine should not be stored in the fridge.

Make sure that the medicine is out of the sight and reach of children.

Keep the medication in its original container.

Keep Tranexamic Acid at room temperature.

Don't discard this medication in wastewater, i.e. in the toilet or down the drain, or in household trash. Ask your pharmacist about how to safely discard medicines that have expired or are not needed anymore.


You may be given Tranexamic acid injection for other reasons. Make sure to talk to your physician about this.

Use Cyklokapron as directed by your physician. Read all the information provided. Follow all directions carefully.

Cyklokapron is administered through an IV as an injection into your vein.

If your medical problems or symptoms don't improve or they deteriorate, call your doctor promptly.

Some medicines may come with an additional information leaflet. Find out if your medicine is one of them from your pharmacist. Please consult all your healthcare givers if you have questions about Cyklokapron.

If you want to keep Cyklokapron at home, speak to your doctor, pharmacist, or nurse about how to do it.

If there's a Cyklokapron overdose, seek medical care or contact your poison control agency promptly. Be willing to demonstrate what drug was taken, when it happened, and how much of the drug was taken.

Last Reviewed:
December 24, 2017
Last Updated:
April 03, 2018
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