Yohimbine (Oral)

Yohimbine is found in a wide number of supplements, and a number of studies have been carried out that demonstrate its effects at achieving its intended purposes.


Yohimbine originates from the Yohimbe tree, which is located in Central Africa. For many years, the Yohimbe tree has been known to local West Africans as the "love tree". That is because its aphrodisiac capabilities have been known of - and widely used - for many years. The first people to start using Yohimbe extract were Bushments, Pygmies, and tribes from Nigeria, Gabon, and Cameroon. It has long been thought to improve your sexual abilities, stamina, pleasure and, of course, your sexual drive. Yohimbe is now available all around the world, because making it no longer requires tearing down Yohimbe trees. Instead, in 1896, researchers took a sample to a lab and were able to synthetically reproduce an alkaloid compound in the bark, which is now known as Yohimbine.

Yohimbine is most commonly used as either a fat burner or as an aphrodisiac. It has been used widely to counter the effects of erectile dysfunction and to improve upon the body's ability to burn fat. Those taking Yohimbine find that consuming food alongside it will negate much of the fat burning effects of it, so will instead take Yohimbine while in a state of fasting. It acts by boosting adrenaline levels, while simultaneously regulating agents in blood cells.

However, there are a number of issues surrounding Yohimbine, not least the fact that most supplements containing it are very poorly labeled, and fail to properly highlight the amount of Yohimbine present. Yohimbine can also have severe psychological effects, especially with regards to individuals who already suffer from anxiety or bipolar disorder. Before taking Yohimbine, always consult a doctor if you are on any other form of medication, or you are predisposed to sensitivity.

Condition(s) treated

  • Erectile dysfunction
  • Fat loss

Type of medicine

  • Capsules

Side Effects

Common side effects of taking Yohimbine can include dizziness, nervousness, abdominal pain or nausea. If patients are predisposed to anxiety, then Yohimbine can have much larger neurological effects, and trigger manic psychosis. For those who suffer from bipolar disorder, it can lead to suicidal tendencies.

For this reason, be sure to consult your doctor before taking Yohimbine if you are at all worried about the adverse psychological effects it could have.


In order to increase your levels of fat burning, here is the recommended dosage based on your weight:

  • 14mg if you are 150lb
  • 18mg if you are 200lb
  • 22mg if you are 250lb

Essentially, a dosage of 0.2mg/kg of body weight have been safely taken to ensure higher levels of fat burning, while not having any negative effects on heart rate or blood pressure.

Here are some other points to bear in mind:

  • Doses should be taken during periods of short-term fasting, or between meals.
  • Yohimbine is a stimulatory agent so, if you are of a large weight, then taking a large dose could affect your cardiovascular system.
  • If you are new to Yohimbine, then start with half a recommended dose to see how your body reacts.
  • Many Yohimbine supplements often incorrectly label the amount of Yohimbine it contains. In fact, the actual dose could be anywhere from 25% to 150% as stated, so start small.
  • If you are taking Yohimbine alongside another supplement, start out with just a half dose on each and work your way up.

If you are at all worried about taking Yohimbine and are not 100% sure that your own medical health is suitable for starting on a course of Yohimbine, then first consult with your doctor. Having done so, never exceed the recommended doses as stated by your doctor. Much of the packaging and online information surrounding Yohimbine is inaccurate, so it should be taken with caution.


  • The fat burning capabilities of Yohimbine are said to be reduced when patients also consume food at the same time. This is why Yohimbine is commonly taken during states of fasting.
  • Yohimbine has been shown to be able to lessen the effects of Nortriptyline.
  • Yohimbine can fail to improve intended gastric emptying if patients are on around 50mg ephedrine.
  • Yohimbine counteracts the effects of other anti-aphrodisiac drugs such as clonidine or naloxone.
  • Yohimbine may be able to induce stress, anxiety and panic attacks. However, some of these effects can be negated by diazepam and clonidine.
  • Yohimbine can improve cognitive arithmetic abilities, though it does also increase errors as well.
  • Yohimbine can decrease cerebral blood flow.
  • Yohimbine, if taken with ephedrine and caffeine, has been found to reduce cardiac work when at rest.
  • Sibutramine is a drug that has now been withdrawn from the market, as it was deemed unsafe and had negative effects on cardiovascular activity. If used in conjunction with Yohimbine, then this can counter the systematic increase in adrenaline levels expected from sibutramine.
  • Yohimbine has been found to increase the effects of viagra on sexual arousal among men. This is said to be true, even if the Yohimbine itself has little effect on negating erectile dysfunction.
  • When used alongside L-Arginine, the erectile dysfunction combating effects of Yohimbine seem to be improved. However, this is more the case for those suffering from mild to moderate erectile dysfunction, rather than severe.
  • Tests were carried out among women to see if a cream version of Yohimbine would be effective in reducing fat levels on thighs. Results came back mixed and largely inconclusive, but found that forskolin or aminophylline worked better.
  • Tests carried out on men have found that the arousing effects of Yohimbine are not associated with an increase in testosterone levels.
  • While Yohimbine seems to have effects on decreasing the levels of fat, it doesn't have an effect on physical performance or the development of lean mass.
  • When used at 5.4mg doses, Yohimbine is found to be a more effective treatment for orthostatic hypotension, rather than 60mg of pyridostigmine. This is because Yohimbine has the effect of increasing blood pressure, which counteracts the lightheadedness associated with a fall in cerebral blood pressure levels.
  • Studies undertaken with groups of football players found that Yohimbine did indeed lead to reduced fat levels, compared to those players just taking placebos. However, they found the effects were enhanced when taken alongside beta-blockers.


  • For individuals predisposed to anxiety, Yohimbine can trigger manic psychosis.
  • For those with bipolar disorder, it can trigger suicidal episodes.
  • It is known to interact with a number of neurological medications, so should not be used alongside these unless recommended by a doctor.

There have been some noted adverse effects on persons taking Yohimbine at 5.4mg three times a day to counter erectile dysfunction. This includes:

  • Nausea
  • Nervousness
  • Dizziness
  • Abdominal pain

Some patients who took higher doses (15-20mg range) have also been found to possibly develop hypertension or tachycardia (an irregular heartbeat).

Studies taken out to analyze the correct labeling of Yohimbine products have found that the actual percentages contained are between 25% to 150% of that stated. Very few labels are found to have correct dosages labeled, and others do not warn of any adverse side-effects of Yohimbine.

Do not take Yohimbine, or at least first consult with a doctor, if you suffer from any of the following:

  • Ulcers in the intestines or stomach
  • Mood disorders
  • Allergies to other ingredients contained alongside Yohimbine
  • Respiratory problems
  • Liver or kidney troubles
  • If on antidepressants or other IMOs
  • If pregnant or planning on becoming pregnant
  • If elderly, as Yohimbine effects may be intensified.


Yohimbine should be stored at room temperature, between 60 and 85 degrees Fahrenheit. It should not be stored in a fridge or freezer and should be kept away from direct sunlight. Avoid areas that are prone to high moisture or humidity, as this can also compromise the integrity of the tablets. Be sure to keep Yohimbine away from children. As with any supplement or medication, once Yohimbine has gone out of date, dispose of it safely and do not continue to use.


There are still those that doubt the effectiveness of Yohimbine in burning fat or in its ability to counter erectile dysfunction. Many who use it may be quick to read the claims on the packaging, rather than look into the medical proof or risks associated with it. In fact, much of the packaging of Yohimbine fails completely to list any of the possible side effects and is usually completely inaccurate in stating the actual percentage of Yohimbine that is present. For this reason, before starting on a course of Yohimbine, it is best to first consult with a medical professional. They will be able to assess whether it is likely to have any adverse effects on you physically or psychologically. If so, it is likely that they will be able to prescribe an alternate form of medication that you may be much better suited to.


Last Reviewed:
December 23, 2017
Last Updated:
April 05, 2018
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