Islet Cell Cancer is an umbrella term used to describe a subset of cancers. These cancers are located in the pancreas, and attach themselves to hormone producing cells that produce insulin and glucogon. These cancers are also referred to as pancreatic neuroendocrine tumors and they are extremely rare.
The islet cells referred to in the term are responsible for producing hormones inside the pancreas. Some of the affected cells may still produce hormones, but generally produce more of the hormone than the body can use.
If the tumor is malignant, it can easily spread throughout the body via the bloodstream. Pancreatic cancer is considered to be extremely dangerous, and the prognosis is quite grim from the day of diagnosis. It is very important that patients follow their doctor’s directions, and their treatment plan carefully.
Pancreatic islet cell tumors are also referred to by other names by doctors. These names are:
Islet cell cancerous tumors can be classified into two main categories, functional or nonfunctional. The subtypes are further broken down into the following tumor types:
Rare Functional Tumors
There are a few types of tumors that are considered functional islet cell tumors. However, these are extremely rare, even in comparison to the umbrella term that they are classified under. These rare tumors include:
Somatostatinomas – Releases the hormone somatostatin, which is responsible for determining and controlling the amount of sodium, water, and glucose that leaves the body.
Islet cell tumors can cause a lot of different symptoms, all of which depend on the type of hormone producing cells that it develops from. Usually, the symptoms presented by nonfunctional tumors are created by the tumor metastasizing or growing.
For patients who are experiencing functional tumors, the symptoms produced will be determined by the type of hormone that it is secreting.
Symptoms of Nonfunctional Tumors
Symptoms of Gastrinomas
Symptoms of Insulinomas
The most common treatment for malignant tumors is surgical removal. Many times, surgeons are unable to remove the entire tumor, but they do remove as much as possible so that chemotherapy and radiation are more effective.
Benign tumors are usually left alone, unless they cause severe symptoms or pain. Medications are usually prescribed to control the symptoms the tumor produces. Most functional tumors fall into the category of benign tumors.